Guy Arnold

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi request reprint Steele-Richardson-Olszewski-syndrome: reduction of dopamine D2 receptor binding relates to the severity of midbrain atrophy in vivo: (123)IBZM SPECT and MRI study
    Guy Arnold
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians Universitat Munchen, Munchen, Germany
    Mov Disord 17:557-62. 2002
  2. ncbi request reprint High doses of pergolide improve clinical global impression in advanced Parkinson's disease:- a preliminary open label study
    Guy Arnold
    Department of Neurology, Charite, University Hospital Berlin, Schumannstrasse 20 21, D 10117 Berlin, Germany
    Arch Gerontol Geriatr 41:239-53. 2005
  3. ncbi request reprint [Inhibition of catechol-O-methyltransferase. Optimizing dopaminergic therapy in idiopathic Parkinson syndrome with entacapone]
    G Arnold
    Neurologische Klinik und Poliklinik, Universitatsklinikum Charite, Humboldt Universitat Berlin
    Nervenarzt 71:78-83. 2000
  4. ncbi request reprint Pergolide versus levodopa monotherapy in early Parkinson's disease patients: The PELMOPET study
    Wolfgang H Oertel
    Department of Neurology, Philipps University, Marburg, Germany
    Mov Disord 21:343-53. 2006
  5. ncbi request reprint Cluster-like headache time-locked to the menstrual cycle
    Gabor C Petzold
    Department of Neurology, Charite Hospital, Humboldt University, Berlin, Germany
    Neurology 60:1049. 2003
  6. ncbi request reprint Deep brain stimulation in dystonia
    Andreas Kupsch
    Dept of Neurology and Neurosurgery, Augustenburger Platz 1, 13353 Berlin, Germany
    J Neurol 250:I47-52. 2003
  7. ncbi request reprint A fluorescence-based method to assess plasma protein extravasation in rat dura mater using confocal laser scanning microscopy
    Sigrid Schuh-Hofer
    Department of Experimental Neurology, Humboldt University Berlin Charité, Campus Mitte, Schumannstr 20 21, 10117, Berlin, Germany
    Brain Res Brain Res Protoc 12:77-82. 2003
  8. ncbi request reprint The effects of frequency in pallidal deep brain stimulation for primary dystonia
    A Kupsch
    Dept of Neurology, Charite, Campus Virchow, Humboldt University Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    J Neurol 250:1201-5. 2003
  9. ncbi request reprint Combined 123I-FP-CIT and 123I-IBZM SPECT for the diagnosis of parkinsonian syndromes: study on 72 patients
    M Plotkin
    Klinik fur Strahlenheilkunde, Campus Virchow Klinikum, Charite Universitatsmedizin, Berlin, Germany
    J Neural Transm 112:677-92. 2005
  10. ncbi request reprint Monozygotic twin sisters suffering from cluster headache and migraine without aura
    S Schuh-Hofer
    Department of Neurology, Humboldt University Berlin Charité, Germany
    Neurology 60:1864-5. 2003

Collaborators

Detail Information

Publications31

  1. ncbi request reprint Steele-Richardson-Olszewski-syndrome: reduction of dopamine D2 receptor binding relates to the severity of midbrain atrophy in vivo: (123)IBZM SPECT and MRI study
    Guy Arnold
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians Universitat Munchen, Munchen, Germany
    Mov Disord 17:557-62. 2002
    ..010) either in all 13 patients or in those without striatal or white matter lesions (P = 0.015). We suggest that technical investigations, mainly MRI, are able to corroborate the in vivo diagnosis, if PSP is clinically suspected...
  2. ncbi request reprint High doses of pergolide improve clinical global impression in advanced Parkinson's disease:- a preliminary open label study
    Guy Arnold
    Department of Neurology, Charite, University Hospital Berlin, Schumannstrasse 20 21, D 10117 Berlin, Germany
    Arch Gerontol Geriatr 41:239-53. 2005
    ..A possible relationship to the study medication was assumed for two serious adverse events reporting psychosis. We conclude that high doses of pergolide are efficacious in advanced stages of PD if given in appropriate regimens...
  3. ncbi request reprint [Inhibition of catechol-O-methyltransferase. Optimizing dopaminergic therapy in idiopathic Parkinson syndrome with entacapone]
    G Arnold
    Neurologische Klinik und Poliklinik, Universitatsklinikum Charite, Humboldt Universitat Berlin
    Nervenarzt 71:78-83. 2000
    ..We review data, especially on the remaining COMT inhibitor, entacapone, with regard to pre-clinical and clinical efficacy and safety...
  4. ncbi request reprint Pergolide versus levodopa monotherapy in early Parkinson's disease patients: The PELMOPET study
    Wolfgang H Oertel
    Department of Neurology, Philipps University, Marburg, Germany
    Mov Disord 21:343-53. 2006
    ..In principle, both levodopa and a dopamine agonist such as pergolide seem to be suitable options as initial PD therapy. The choice remains with the treating physician based on the different efficacy and adverse event profiles...
  5. ncbi request reprint Cluster-like headache time-locked to the menstrual cycle
    Gabor C Petzold
    Department of Neurology, Charite Hospital, Humboldt University, Berlin, Germany
    Neurology 60:1049. 2003
  6. ncbi request reprint Deep brain stimulation in dystonia
    Andreas Kupsch
    Dept of Neurology and Neurosurgery, Augustenburger Platz 1, 13353 Berlin, Germany
    J Neurol 250:I47-52. 2003
    ..Furthermore, the optimal target for different dystonic disorders remains to be determined, although the globus pallidus internus has currently emerged as the most promising target for dystonia...
  7. ncbi request reprint A fluorescence-based method to assess plasma protein extravasation in rat dura mater using confocal laser scanning microscopy
    Sigrid Schuh-Hofer
    Department of Experimental Neurology, Humboldt University Berlin Charité, Campus Mitte, Schumannstr 20 21, 10117, Berlin, Germany
    Brain Res Brain Res Protoc 12:77-82. 2003
    ..Our results are in accordance with previous reports in the literature using the radioactive approach. We conclude that CLSM is a safe, sensitive, and reliable method to assess PPE in rat meninges in an experimental migaine model...
  8. ncbi request reprint The effects of frequency in pallidal deep brain stimulation for primary dystonia
    A Kupsch
    Dept of Neurology, Charite, Campus Virchow, Humboldt University Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    J Neurol 250:1201-5. 2003
    ..Compared with 130 Hz a significant further clinical improvement was observed at frequencies of 180 and 250 Hz, which contrasted with a significant deterioration at lower frequencies (5, 50 Hz) compared to 130 Hz...
  9. ncbi request reprint Combined 123I-FP-CIT and 123I-IBZM SPECT for the diagnosis of parkinsonian syndromes: study on 72 patients
    M Plotkin
    Klinik fur Strahlenheilkunde, Campus Virchow Klinikum, Charite Universitatsmedizin, Berlin, Germany
    J Neural Transm 112:677-92. 2005
    ..IBZM SPECT is useful to approve the diagnosis of PSP and MSA although a normal finding cannot exclude an atypical PS. IBZM SPECT seems to be of restricted value in CBD...
  10. ncbi request reprint Monozygotic twin sisters suffering from cluster headache and migraine without aura
    S Schuh-Hofer
    Department of Neurology, Humboldt University Berlin Charité, Germany
    Neurology 60:1864-5. 2003
  11. ncbi request reprint Sympathetic activation due to deep brain stimulation in the region of the STN
    A Lipp
    Department of Neurology, Medical Faculty of the Charite, Berlin, Germany
    Neurology 65:774-5. 2005
  12. pmc Ischaemia triggered by spreading neuronal activation is inhibited by vasodilators in rats
    J P Dreier
    Department of Experimental Neurology, Humboldt University, Berlin, Germany
    J Physiol 531:515-26. 2001
    ..Speculatively, this pathogenetic process could be involved in migraine-induced stroke...
  13. ncbi request reprint The interrelations of migraine, vertigo, and migrainous vertigo
    H Neuhauser
    Neurologische Klinik, Charite, Humboldt Universitat, Berlin, Germany
    Neurology 56:436-41. 2001
    ..To assess the prevalence of migrainous vertigo in patients with migraine and in patients with vertigo according to explicit diagnostic criteria that are presented for discussion...
  14. ncbi request reprint Relative quantification of signal on T2-weighted images in the basal ganglia: limited value in differential diagnosis of patients with parkinsonism
    J Schwarz
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    Neuroradiology 41:124-8. 1999
    ..However, this method does not exclude idiopathic parkinsonism in a given patient...
  15. ncbi request reprint The use of radiolabelled human serum albumin and SPECT/MRI co-registration to study inflammation in the cavernous sinus of cluster headache patients
    S Schuh-Hofer
    Department of Neurology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Cephalalgia 26:1115-22. 2006
    ..There was no evidence for 99mTc-HSA extravasation in the cavernous sinus during the active episode as compared with the remission phase. Our results do not support the hypothesis of an inflammation in the cavernous sinus...
  16. ncbi request reprint [Migrainous vertigo]
    M von Brevern
    Neurologische Klinik, Campus Virchow Klinkum der Charité Berlin
    Schmerz 18:411-4. 2004
    ..We propose that the diagnosis of definite migrainous vertigo can be made in a patient with migraine according to the IHS with at least two attacks of vestibular vertigo accompanied by migrainous symptoms when other causes are excluded...
  17. ncbi request reprint Effect of hyperoxia on neurogenic plasma protein extravasation in the rat dura mater
    Sigrid Schuh-Hofer
    Department of Neurology, Charite Universitatsmedizin, Berlin, Germany
    Headache 46:1545-51. 2006
    ..We aimed to study the effect of normobaric hyperoxia on neurogenic inflammation of the rat dura mater...
  18. ncbi request reprint 3H-spiperone binding to lymphocytes fails in the differential diagnosis of de novo Parkinson syndromes
    G Arnold
    Department of Neurology, Ludwig Maximilians Universitat Munchen, Federal Republic of Germany
    J Neural Transm Park Dis Dement Sect 5:107-16. 1993
    ..It is concluded that at present 3H-spiperone binding gives no further information in the differential diagnosis of de novo Parkinson's disease...
  19. ncbi request reprint Subthalamic stimulation differentially modulates declarative and nondeclarative memory
    Thomas D Hälbig
    Department of Neurology, Charite University Medicine Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, D 13353 Berlin, Germany
    Neuroreport 15:539-43. 2004
    ....
  20. ncbi request reprint Egocentric and allocentric spatial memory in idiopathic cervical dystonia
    Christoph J Ploner
    Klinik fur Neurologie, Charite, Berlin, Germany
    Neurology 64:1733-8. 2005
    ..To investigate whether impaired spatial memory contributes to cognitive deficits in idiopathic cervical dystonia (ICD)...
  21. ncbi request reprint A randomized trial of botulinum toxin A for treatment of drooling
    A Lipp
    Department of Neurology, Medical Faculty of the Charite, Humboldt University, Berlin, Germany
    Neurology 61:1279-81. 2003
    ..The primary endpoint was achieved with 75 MU BTX-A without treatment-related adverse events, suggesting BTX-A is a safe and effective treatment for patients with sialorrhea...
  22. ncbi request reprint Perivascular nerves contribute to cortical spreading depression-associated hyperemia in rats
    U Reuter
    Department of Neurology, Charite Hospital, Humboldt University, 10098 Berlin, Germany
    Am J Physiol 274:H1979-87. 1998
    ..We conclude that CSD-associated hyperperfusion is mediated in part by a depolarization of trigeminal sensory and parasympathetic nerve fibers, resulting in a release of vasoactive trigeminal and parasympathetic neurotransmitters...
  23. pmc Preventive antibacterial therapy in acute ischemic stroke: a randomized controlled trial
    Hendrik Harms
    Department of Neurology, Charite Universitaetsmedizin Berlin, Berlin, Germany
    PLoS ONE 3:e2158. 2008
    ..In this study we investigate whether this approach is effective in stroke patients...
  24. ncbi request reprint Migraine with aura shows gadolinium enhancement which is reversed following prophylactic treatment
    G Arnold
    Department of Neurology, Humboldt Universitat, Charite, Berlin, Germany
    Cephalalgia 18:644-6. 1998
    ..The migraine attacks and Gd-DTPA enhancement were reversible during prophylactic treatment with flunarizine...
  25. ncbi request reprint Neurostimulation of the ventral intermediate thalamic nucleus in inherited myoclonus-dystonia syndrome
    T Trottenberg
    Department of Neurology, Humboldt-University, , Berlin, Germany
    Mov Disord 16:769-71. 2001
    ..This suggests that neurostimulation of the VIM may be an effective treatment for myoclonus in pharmacologically intractable IMDS...
  26. ncbi request reprint Osmosensitive mechanisms contribute to the water drinking-induced pressor response in humans
    A Lipp
    Department of Neurology, Medical University Charité, Berlin, Germany
    Neurology 65:905-7. 2005
    ..We reasoned that gastrointestinal distention, hyposomotic stimulation, or both contribute to the water-induced pressor response...
  27. ncbi request reprint CGRP release and c-fos expression within trigeminal nucleus caudalis of the rat following glyceryltrinitrate infusion
    N Offenhauser
    Department of Neurology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Cephalalgia 25:225-36. 2005
    ..Both GTN and L-NAME reduced capsaicin-induced c-fos LI. This is most likely due to a feedback inhibition of nitric oxide synthases, which indicates that the c-fos response to capsaicin within TNC is mediated by NO dependent mechanisms...
  28. pmc Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFE
    Hans Christoph Diener
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Lancet Neurol 7:875-84. 2008
    ..The putative neuroprotective effects of antiplatelet compounds and the angiotensin II receptor antagonist telmisartan were investigated in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial...
  29. ncbi request reprint Increased serotonin transporter availability in the brainstem of migraineurs
    Sigrid Schuh-Hofer
    Dept of Neurology, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Neurol 254:789-96. 2007
    ..It remains to be elucidated whether the altered SERT-availability is causally related to migraine pathophysiology or whether it reflects secondary pathophysiological mechanisms...
  30. ncbi request reprint Effects of parecoxib on plasma protein extravasation and c-fos expression in the rat
    Sigrid Schuh-Hofer
    Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Headache 46:276-85. 2006
    ..Background.-Recent reports about the efficacy of COX-2 inhibitors in migraine treatment suggest the involvement of COX-2 in migraine pathophysiology. So far, studies on the role of COX-2 in animal models of migraine are lacking...
  31. ncbi request reprint Treatment of acute cluster headache with 20 mg sumatriptan nasal spray--an open pilot study
    Sigrid Schuh-Hofer
    Dept of Neurology, Charite, Berlin, Germany
    J Neurol 249:94-9. 2002
    ..We conclude that 20 mg sumatriptan nasal spray might be an alternative therapy for the treatment of cluster headache attacks, but double-blind studies are needed to further evaluate its efficacy...