Edgar Holznagel

Summary

Country: Germany

Publications

  1. ncbi request reprint Immunological changes in simian immunodeficiency virus (SIV(agm))-infected African green monkeys (AGM): expanded cytotoxic T lymphocyte, natural killer and B cell subsets in the natural host of SIV(agm)
    Edgar Holznagel
    Paul Ehrlich Institute, Paul Ehrlich Str 51 59, 63225 Langen, Germany
    J Gen Virol 83:631-40. 2002
  2. pmc Foodborne transmission of bovine spongiform encephalopathy to nonhuman primates
    Edgar Holznagel
    Paul Ehrlich Institut, Langen, Germany
    Emerg Infect Dis 19:712-20. 2013
  3. doi request reprint Increase in CD230 (cellular prion protein) fluorescence on blood lymphocytes in bovine spongiform encephalopathy-infected nonhuman primates
    Edgar Holznagel
    Paul Ehrlich Institut, Federal Agency for Vaccines and Biomedicines, Langen, Germany
    Transfusion 50:452-66. 2010
  4. pmc Dominance of highly divergent feline leukemia virus A progeny variants in a cat with recurrent viremia and fatal lymphoma
    A Katrin Helfer-Hungerbuehler
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    Retrovirology 7:14. 2010
  5. ncbi request reprint Time-course studies of 14-3-3 protein isoforms in cerebrospinal fluid and brain of primates after oral or intracerebral infection with bovine spongiform encephalopathy agent
    Barbara Yutzy
    Paul Ehrlich Institut, Langen, Germany
    J Gen Virol 88:3469-78. 2007
  6. pmc Engineered CD4- and CXCR4-using simian immunodeficiency virus from African green monkeys is neutralization sensitive and replicates in nonstimulated lymphocytes
    Renate R König
    Department of Medical Biotechnology, Paul Ehrlich Institut, 63225 Langen, Germany
    J Virol 76:10627-36. 2002
  7. doi request reprint Foodborne-Transmitted Prions From the Brain of Cows With Bovine Spongiform Encephalopathy Ascend in Afferent Neurons to the Simian Central Nervous System and Spread to Tonsils and Spleen at a Late Stage of the Incubation Period
    Edgar Holznagel
    Paul Ehrlich Institut, Federal Institute for Vaccines and Biomedicines, Langen
    J Infect Dis 212:1459-68. 2015
  8. doi request reprint Squalene-containing licensed adjuvants enhance strain-specific antibody responses against the influenza hemagglutinin and induce subtype-specific antibodies against the neuraminidase
    Rebecca Schmidt
    Veterinary Medicine, Paul Ehrlich Institut, Federal Institute for Vaccines and Biomedicines, 63225 Langen, Germany
    Vaccine 34:5329-5335. 2016

Collaborators

  • Cheick Coulibaly
  • Britta Neumann
  • Michael Beekes
  • Egbert Flory
  • Rebecca Schmidt
  • A Katrin Helfer-Hungerbuehler
  • Barbara Yutzy
  • Veronika von Messling
  • Ralf Wagner
  • Carina Kruip
  • Nina Alex
  • Theresa Enkirch
  • Kristin Pfeffermann
  • Bevan Sawatsky
  • Renate R König
  • Manfred Henrich
  • Regina Hofmann-Lehmann
  • Hans Lutz
  • Manfred Reinacher
  • Eva Bauer
  • Paula Grest
  • Felicitas S Boretti
  • Eva Niederer
  • Pete Ossent
  • Valentino Cattori
  • Kim Bauer-Pham
  • Gerhard Hunsmann
  • Jean Philippe Deslys
  • Uwe Hahmann
  • Johannes Lower
  • Andreas Stuke
  • Stefanie Steidl
  • Klaus Cichutek
  • Silke Holzammer
  • Stephen Norley
  • Jeanette Neumann

Detail Information

Publications8

  1. ncbi request reprint Immunological changes in simian immunodeficiency virus (SIV(agm))-infected African green monkeys (AGM): expanded cytotoxic T lymphocyte, natural killer and B cell subsets in the natural host of SIV(agm)
    Edgar Holznagel
    Paul Ehrlich Institute, Paul Ehrlich Str 51 59, 63225 Langen, Germany
    J Gen Virol 83:631-40. 2002
    ....
  2. pmc Foodborne transmission of bovine spongiform encephalopathy to nonhuman primates
    Edgar Holznagel
    Paul Ehrlich Institut, Langen, Germany
    Emerg Infect Dis 19:712-20. 2013
    ..This finding could affect diagnosis of variant Creutzfeldt-Jakob disease in humans and might be relevant for retrospective studies of positive tonsillectomy or appendectomy specimens because time of infection is unknown...
  3. doi request reprint Increase in CD230 (cellular prion protein) fluorescence on blood lymphocytes in bovine spongiform encephalopathy-infected nonhuman primates
    Edgar Holznagel
    Paul Ehrlich Institut, Federal Agency for Vaccines and Biomedicines, Langen, Germany
    Transfusion 50:452-66. 2010
    ..This disease can be transmitted by blood transfusion. However, the exact kinetics of blood infectivity and the blood fraction carrying infectivity have not yet been identified...
  4. pmc Dominance of highly divergent feline leukemia virus A progeny variants in a cat with recurrent viremia and fatal lymphoma
    A Katrin Helfer-Hungerbuehler
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    Retrovirology 7:14. 2010
    ..5 years after the initial experimental exposure to FeLV-A/Glasgow-1. The goals of the present study were to investigate this FeLV reoccurrence and molecularly characterize the progeny viruses...
  5. ncbi request reprint Time-course studies of 14-3-3 protein isoforms in cerebrospinal fluid and brain of primates after oral or intracerebral infection with bovine spongiform encephalopathy agent
    Barbara Yutzy
    Paul Ehrlich Institut, Langen, Germany
    J Gen Virol 88:3469-78. 2007
    ..However, there are differences in the clinical course between orally and intracerebrally infected animals that may influence the detection of other biomarkers...
  6. pmc Engineered CD4- and CXCR4-using simian immunodeficiency virus from African green monkeys is neutralization sensitive and replicates in nonstimulated lymphocytes
    Renate R König
    Department of Medical Biotechnology, Paul Ehrlich Institut, 63225 Langen, Germany
    J Virol 76:10627-36. 2002
    ..Our study describes for the first time a successful exchange of a V3 loop in nonpathogenic SIVagm resulting in CD4 and CXCR4 usage and modulation of virus replication in nonstimulated PBMCs as well as sensitivity toward neutralization...
  7. doi request reprint Foodborne-Transmitted Prions From the Brain of Cows With Bovine Spongiform Encephalopathy Ascend in Afferent Neurons to the Simian Central Nervous System and Spread to Tonsils and Spleen at a Late Stage of the Incubation Period
    Edgar Holznagel
    Paul Ehrlich Institut, Federal Institute for Vaccines and Biomedicines, Langen
    J Infect Dis 212:1459-68. 2015
    ..However, the temporal sequence of prion spread in the human body is still not known. We therefore traced the temporal-spatial pattern of PrP(res) accumulation in the body of a simian vCJD model...
  8. doi request reprint Squalene-containing licensed adjuvants enhance strain-specific antibody responses against the influenza hemagglutinin and induce subtype-specific antibodies against the neuraminidase
    Rebecca Schmidt
    Veterinary Medicine, Paul Ehrlich Institut, Federal Institute for Vaccines and Biomedicines, 63225 Langen, Germany
    Vaccine 34:5329-5335. 2016
    ....