Bernd Hohenstein

Summary

Country: Germany

Publications

  1. doi request reprint Peritubular capillaries: an important piece of the puzzle
    Bernd Hohenstein
    Division of Nephrology, Department of Internal Medicine III, Technische Universitaet Dresden, Dresden, Germany Electronic address
    Kidney Int 91:9-11. 2017
  2. doi request reprint Abstracts
    Bernd Hohenstein
    Endowed Chair for Extracorporal Treatments and Lipoprotein Apheresis, Professor of Medicine, Consultant Nephrologist, Head Extracorporeal Treatment and Lipoprotein Apheresis Center, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technischen Universitaet Dresden, Dresden, Germany
    Ther Apher Dial 20:540-546. 2016
  3. doi request reprint Immunoadsorption with regenerating systems in neurological disorders --A single center experience
    Bernd Hohenstein
    Extracorporeal Treatment and Apheresis Center, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Germany Division of Nephrology, Department of Internal Medicine III, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Germany Electronic address
    Atheroscler Suppl 18:119-23. 2015
  4. doi request reprint Immunoadsorption for connective tissue disease
    B Hohenstein
    Department of Internal Medicine III, University Hospital Carl Gustav Carus, Fetscherstr 74, 01307 Dresden, Germany
    Atheroscler Suppl 14:185-9. 2013
  5. pmc Enhanced progenitor cell recruitment and endothelial repair after selective endothelial injury of the mouse kidney
    Bernd Hohenstein
    Division of Nephrology, Department of Internal Medicine III, University of Technology Dresden, Germany
    Am J Physiol Renal Physiol 298:F1504-14. 2010
  6. doi request reprint Autocrine VEGF-VEGF-R loop on podocytes during glomerulonephritis in humans
    Bernd Hohenstein
    Division of Nephrology, Medical Clinic III, University of Dresden, Dresden, Germany
    Nephrol Dial Transplant 25:3170-80. 2010
  7. doi request reprint Platelets are not critical effector cells for the time course of murine passive crescentic glomerulonephritis
    Bernd Hohenstein
    Division of Nephrology, Department of Internal Medicine III, University of Technology, Dresden, Germany
    Platelets 24:267-74. 2013
  8. doi request reprint Acetylation of asymmetric and symmetric dimethylarginine: an undercharacterized pathway of metabolism of endogenous methylarginines
    Roman N Rodionov
    University Center for Vascular Medicine and Division of Angiology, Department of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Fetscherstraße 74, 01307 Dresden, Germany
    Nephrol Dial Transplant 31:57-63. 2016
  9. ncbi request reprint Vasodilator-stimulated phosphoprotein-deficient mice demonstrate increased platelet activation but improved renal endothelial preservation and regeneration in passive nephrotoxic nephritis
    Bernd Hohenstein
    Division of Nephrology, University Erlangen Nuremberg, Loschgestrasse 8, Erlangen 91054, Germany
    J Am Soc Nephrol 16:986-96. 2005
  10. pmc Extrarenal Progenitor Cells Do Not Contribute to Renal Endothelial Repair
    Jan Sradnick
    Division of Nephrology, Department of Internal Medicine III, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany and
    J Am Soc Nephrol 27:1714-26. 2016

Collaborators

Detail Information

Publications18

  1. doi request reprint Peritubular capillaries: an important piece of the puzzle
    Bernd Hohenstein
    Division of Nephrology, Department of Internal Medicine III, Technische Universitaet Dresden, Dresden, Germany Electronic address
    Kidney Int 91:9-11. 2017
    ....
  2. doi request reprint Abstracts
    Bernd Hohenstein
    Endowed Chair for Extracorporal Treatments and Lipoprotein Apheresis, Professor of Medicine, Consultant Nephrologist, Head Extracorporeal Treatment and Lipoprotein Apheresis Center, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technischen Universitaet Dresden, Dresden, Germany
    Ther Apher Dial 20:540-546. 2016
    ..Overall, more than 70 individual contributions helped to keep up a lively discussion and interaction of all participants. This issue publishes a selection of submitted abstracts...
  3. doi request reprint Immunoadsorption with regenerating systems in neurological disorders --A single center experience
    Bernd Hohenstein
    Extracorporeal Treatment and Apheresis Center, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Germany Division of Nephrology, Department of Internal Medicine III, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Germany Electronic address
    Atheroscler Suppl 18:119-23. 2015
    ..Regenerating systems offer the perspective to provide a more efficacious long term treatment perspective for such patients. ..
  4. doi request reprint Immunoadsorption for connective tissue disease
    B Hohenstein
    Department of Internal Medicine III, University Hospital Carl Gustav Carus, Fetscherstr 74, 01307 Dresden, Germany
    Atheroscler Suppl 14:185-9. 2013
    ..Despite the presence of a large number of case series and few controlled trials using IAS, there is a need for further prospective randomized trials to clearly define the role of IAS in these CTD's...
  5. pmc Enhanced progenitor cell recruitment and endothelial repair after selective endothelial injury of the mouse kidney
    Bernd Hohenstein
    Division of Nephrology, Department of Internal Medicine III, University of Technology Dresden, Germany
    Am J Physiol Renal Physiol 298:F1504-14. 2010
    ..Injection of a high dose of erythropoietin 2 h after disease induction markedly attenuated vascular injury through nonhemodynamic mechanisms, possibly involving vascular endothelial growth factor release...
  6. doi request reprint Autocrine VEGF-VEGF-R loop on podocytes during glomerulonephritis in humans
    Bernd Hohenstein
    Division of Nephrology, Medical Clinic III, University of Dresden, Dresden, Germany
    Nephrol Dial Transplant 25:3170-80. 2010
    ..Its activity is critical for capillary/glomerular preservation and repair, and recent studies have also demonstrated its relevance for the preservation of podocytes...
  7. doi request reprint Platelets are not critical effector cells for the time course of murine passive crescentic glomerulonephritis
    Bernd Hohenstein
    Division of Nephrology, Department of Internal Medicine III, University of Technology, Dresden, Germany
    Platelets 24:267-74. 2013
    ..These data indicate that platelets play a minor role during the time course of this disease model in the mouse...
  8. doi request reprint Acetylation of asymmetric and symmetric dimethylarginine: an undercharacterized pathway of metabolism of endogenous methylarginines
    Roman N Rodionov
    University Center for Vascular Medicine and Division of Angiology, Department of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Fetscherstraße 74, 01307 Dresden, Germany
    Nephrol Dial Transplant 31:57-63. 2016
    ..We and others have shown that both ADMA and SDMA can be Nα-acetylated to form asymmetric and symmetric Nα-acetyldimethylarginine (Ac-ADMA and Ac-SDMA). The current study further investigated this undercharacterized metabolic pathway...
  9. ncbi request reprint Vasodilator-stimulated phosphoprotein-deficient mice demonstrate increased platelet activation but improved renal endothelial preservation and regeneration in passive nephrotoxic nephritis
    Bernd Hohenstein
    Division of Nephrology, University Erlangen Nuremberg, Loschgestrasse 8, Erlangen 91054, Germany
    J Am Soc Nephrol 16:986-96. 2005
    ..Despite an enhanced injury response early on, VASP -/- mice are protected from long-term progression of nephrotoxic nephritis, which is associated with improved renal endothelial cell preservation and regeneration...
  10. pmc Extrarenal Progenitor Cells Do Not Contribute to Renal Endothelial Repair
    Jan Sradnick
    Division of Nephrology, Department of Internal Medicine III, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany and
    J Am Soc Nephrol 27:1714-26. 2016
    ..Overall, extrarenal cells did not substitute for any intrinsic ECs. These results demonstrate that endothelial repair in mouse kidneys with acute endothelial lesions depends exclusively on local mechanisms. ..
  11. pmc Platelets are relevant mediators of renal injury induced by primary endothelial lesions
    Claudia Schwarzenberger
    Division of Nephrology, Department of Internal Medicine III, Technische Universitaet Dresden, Dresden, Germany
    Am J Physiol Renal Physiol 308:F1238-46. 2015
    ..While strategies to prevent platelet-endothelial interactions have shown protective effects, the contribution of platelets during renal regeneration remains unknown. ..
  12. doi request reprint Treatment of antibody-mediated rejection including immunoadsorption during first year after renal transplantation--Clinical results and regulation of endothelial progenitor cells
    Mirian Opgenoorth
    University Hospital Carl Gustav Carus at the Technische Universität Dresden, Department of Internal Medicine III, Division of Nephrology, Fetscherstraße 74, 01307 Dresden, Germany
    Atheroscler Suppl 18:67-73. 2015
    ..Yet, other mechanisms contributing to the beneficial effect of apheresis besides the removal of antibodies are under consideration...
  13. pmc Renin lineage cells repopulate the glomerular mesangium after injury
    Charlotte Starke
    Division of Nephrology, Department of Internal Medicine III, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany
    J Am Soc Nephrol 26:48-54. 2015
    ..These data demonstrate that extraglomerular renin lineage cells represent a major source of repopulating cells for reconstitution of the intraglomerular mesangium after injury. ..
  14. doi request reprint The SGLT2 inhibitor empagliflozin ameliorates early features of diabetic nephropathy in BTBR ob/ob type 2 diabetic mice with and without hypertension
    Florian Gembardt
    Division of Nephrology, Department of Internal Medicine III, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany and
    Am J Physiol Renal Physiol 307:F317-25. 2014
    ..In summary, empagliflozin demonstrated significant antihyperglycemic effects, differentially ameliorating early features of diabetic nephropathy in BTBR ob/ob mice with and without hypertension...
  15. doi request reprint Role of alanine:glyoxylate aminotransferase 2 in metabolism of asymmetric dimethylarginine in the settings of asymmetric dimethylarginine overload and bilateral nephrectomy
    Roman N Rodionov
    University Center for Vascular Medicine, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Dresden, Germany
    Nephrol Dial Transplant 29:2035-42. 2014
    ..The goal of our study was to test the hypothesis that AGXT2 is compensatory upregulated in the settings of ADMA overload and bilateral nephrectomy...
  16. pmc Neutrophil Extracellular Trap-Related Extracellular Histones Cause Vascular Necrosis in Severe GN
    Santhosh V R Kumar
    Division of Nephrology, Department of Internal Medicine IV, Ludwig Maximilians University of Munich, Munich, Germany
    J Am Soc Nephrol 26:2399-413. 2015
    ..Together, these results indicate that NET-related histone release during GN elicits cytotoxic and immunostimulatory effects. Furthermore, neutralizing extracellular histones is still therapeutic when initiated in established GN. ..
  17. doi request reprint Increasing plasma lysophosphatidylcholine levels in patients with regular dextran sulfate lipoprotein apheresis
    Juergen Graessler
    Department of Internal Medicine III, University Hospital Carl Gustav Carus, Dresden, TU Dresden, Germany Electronic address
    Atheroscler Suppl 18:170-5. 2015
    ..Therefore, the aim of the present study was to analyze long-term modifications of the plasma lipidomic profile in patients with repeated DSA apheresis...
  18. pmc A new apparatus for standardized rat kidney biopsy
    Holger Schirutschke
    Division of Nephrology, Department of Internal Medicine III, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany
    PLoS ONE 9:e115368. 2014
    ..In summary, our apparatus offers a safe method to perform repetitive kidney biopsies with minimal trauma and sufficient sample size and quality even in experimental disease models restricted to one single kidney. ..