A Hinney

Summary

Country: Germany

Publications

  1. ncbi No evidence for involvement of polymorphisms of the dopamine D4 receptor gene in anorexia nervosa, underweight, and obesity
    A Hinney
    Department of Child and Adolescent Psychiatry, Clinical Research Group, University of Marburg, Germany e
    Am J Med Genet 88:594-7. 1999
  2. ncbi No evidence for involvement of alleles of the 825-C/T polymorphism of the G-protein subunit beta 3 in body weight regulation
    A Hinney
    Clinical Research Group, Department of Child and Adolescent Psychiatry, Philipps University of Marburg, Germany
    Exp Clin Endocrinol Diabetes 109:402-5. 2001
  3. ncbi No evidence for involvement of the promoter polymorphism -866 G/A of the UCP2 gene in childhood-onset obesity in humans
    N Schäuble
    Clinical Research Group, Department of Child and Adolescent Psychiatry, Philipps University of Marburg, Marburg, Germany
    Exp Clin Endocrinol Diabetes 111:73-6. 2003
  4. ncbi Several mutations in the melanocortin-4 receptor gene including a nonsense and a frameshift mutation associated with dominantly inherited obesity in humans
    A Hinney
    Clinical Research Group, Department of Child and Adolescent Psychiatry, University of Marburg, FRG
    J Clin Endocrinol Metab 84:1483-6. 1999
  5. ncbi Independent confirmation of a major locus for obesity on chromosome 10
    A Hinney
    Department of Child and Adolescent Psychiatry, University of Marburg, FRG
    J Clin Endocrinol Metab 85:2962-5. 2000
  6. ncbi Perspectives: molecular genetic research in human obesity
    J Hebebrand
    Clinical Research Group, Department of Child and Adolescent Psychiatry, Philipps University of Marburg, Germany
    Obes Rev 4:139-46. 2003
  7. ncbi Systematic mutation screening of the pro-opiomelanocortin gene: identification of several genetic variants including three different insertions, one nonsense and two missense point mutations in probands of different weight extremes
    A Hinney
    Department of Child and Adolescent Psychiatry, University of Marburg, FRG
    J Clin Endocrinol Metab 83:3737-41. 1998
  8. ncbi Candidate gene polymorphisms in eating disorders
    A Hinney
    Clinical Research Group, Department of Child and Adolescent Psychiatry, Philipps University of Marburg, Hans Sachs Str 6, D 35033, Marburg, Germany
    Eur J Pharmacol 410:147-159. 2000

Collaborators

Detail Information

Publications8

  1. ncbi No evidence for involvement of polymorphisms of the dopamine D4 receptor gene in anorexia nervosa, underweight, and obesity
    A Hinney
    Department of Child and Adolescent Psychiatry, Clinical Research Group, University of Marburg, Germany e
    Am J Med Genet 88:594-7. 1999
    ..1. An influence of alleles of the DRD4 on the development of AN, underweight, or extreme early onset obesity was not detected. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 88:594-597, 1999...
  2. ncbi No evidence for involvement of alleles of the 825-C/T polymorphism of the G-protein subunit beta 3 in body weight regulation
    A Hinney
    Clinical Research Group, Department of Child and Adolescent Psychiatry, Philipps University of Marburg, Germany
    Exp Clin Endocrinol Diabetes 109:402-5. 2001
    ..35; underweight: 0.32). Similarly, genotype frequencies did not differ between the groups. We concluded that the 825-T allele of the GNB3 does not play a major role in weight regulation in German children, adolescents and young adults...
  3. ncbi No evidence for involvement of the promoter polymorphism -866 G/A of the UCP2 gene in childhood-onset obesity in humans
    N Schäuble
    Clinical Research Group, Department of Child and Adolescent Psychiatry, Philipps University of Marburg, Marburg, Germany
    Exp Clin Endocrinol Diabetes 111:73-6. 2003
    ..Allele and genotype frequencies did not differ between the extremely obese and never-obese subjects. In conclusion, we cannot confirm the results of ) in our young sample...
  4. ncbi Several mutations in the melanocortin-4 receptor gene including a nonsense and a frameshift mutation associated with dominantly inherited obesity in humans
    A Hinney
    Clinical Research Group, Department of Child and Adolescent Psychiatry, University of Marburg, FRG
    J Clin Endocrinol Metab 84:1483-6. 1999
    ..Whereas our data support the evidence for dominantly inherited obesity as revealed by the three obese probands with haplo-insufficiency, the functional significance of the missense mutations remains to be determined...
  5. ncbi Independent confirmation of a major locus for obesity on chromosome 10
    A Hinney
    Department of Child and Adolescent Psychiatry, University of Marburg, FRG
    J Clin Endocrinol Metab 85:2962-5. 2000
    ..05. The linkage results confirm the presence of a major susceptibility locus for obesity in a region near the centromere on chromosome 10...
  6. ncbi Perspectives: molecular genetic research in human obesity
    J Hebebrand
    Clinical Research Group, Department of Child and Adolescent Psychiatry, Philipps University of Marburg, Germany
    Obes Rev 4:139-46. 2003
    ..We recommend that the procedure via which a consensus is reached as to what constitutes a true positive association finding requires formalization...
  7. ncbi Systematic mutation screening of the pro-opiomelanocortin gene: identification of several genetic variants including three different insertions, one nonsense and two missense point mutations in probands of different weight extremes
    A Hinney
    Department of Child and Adolescent Psychiatry, University of Marburg, FRG
    J Clin Endocrinol Metab 83:3737-41. 1998
    ..We conclude that the POMC gene harbors several different polymorphisms and mutations, none of which can readily be associated with the phenotypes under study...
  8. ncbi Candidate gene polymorphisms in eating disorders
    A Hinney
    Clinical Research Group, Department of Child and Adolescent Psychiatry, Philipps University of Marburg, Hans Sachs Str 6, D 35033, Marburg, Germany
    Eur J Pharmacol 410:147-159. 2000
    ..This kind of approach has already been initiated for anorexia nervosa. Genetic research on eating disorders will hopefully lead to new pharmacological treatment strategies...