Genomes and Genes
J F Ernst
Affiliation: Heinrich Heine University
- O-glycosylationJ F Ernst
Institut fur Mikrobiologie, Heinnch Heine Universität Düsseldorf, Germany
Med Mycol 39:67-74. 2001..Thus, O-glycosylation processes directly and/or indirectly affect several virulence traits of C. albicans and can be considered as potential antifungal targets...
- Sec20p-interacting proteins (Tip20p, Ufe1p) in the retrograde secretory pathway of the fungal pathogen Candida albicansY Weber
Institut fur Mikrobiologie, Heinrich Heine Universitat, Universitatsstrasse 1, Geb 26 12, 40225 Dusseldorf, Germany
Mol Genet Genomics 268:468-76. 2002..Thus, although the sequences of some components of the ER-tSNARE complex have diverged considerably during evolution, it appears that they have retained similar functions in C. albicans and S. cerevisiae...
- Protein-O-mannosyltransferases in virulence and developmentK B Lengeler
Institut fur Mikrobiologie, Molekulare Mykologie, Heinrich Heine Universitat Dusseldorf, Universitätsstr 1 26 12, 40225, Dusseldorf, Germany
Cell Mol Life Sci 65:528-44. 2008..The susceptibility of human cells to certain viruses may also depend on O-mannosyl chains. This review focuses on the various roles of Pmt proteins in cellular differentiation, development and virulence...
- Flavin mononucleotide-based fluorescent protein as an oxygen-independent reporter in Candida albicans and Saccharomyces cerevisiaeD Tielker
Institut fur Mikrobiologie, Forschungszentrum Julich, Heinrich Heine Universitat Dusseldorf, Dusseldorf, Germany
Eukaryot Cell 8:913-5. 2009..Both species produced CaFbFP and fluoresced even during hypoxia, suggesting that oxygen-independent CaFbFP is a useful, novel tool for monitoring hypoxic gene expression in fungi...
- A potential phosphorylation site for an A-type kinase in the Efg1 regulator protein contributes to hyphal morphogenesis of Candida albicansD P Bockmühl
Institut fur Mikrobiologie, Heinrich Heine Universitat, 40225 Dusseldorf, Germany
Genetics 157:1523-30. 2001..Threonine-206 of Efg1p is essential as a putative phosphorylation target to promote hyphal induction by a subset of environmental cues...
- Review: the Cct eukaryotic chaperonin subunits of Saccharomyces cerevisiae and other yeastsV Stoldt
Heinrich Heine Universitat, Institut fur Mikrobiologie, Dusseldorf, Germany
Yeast 12:523-9. 1996..Cct8p from C. albicans, the only other completely sequenced Cct protein from a fungal species other than S. cerevisiae, is 72% and 61% similar to the S. cerevisiae and mouse Cct8 proteins, respectively...
- Divergence of eukaryotic secretory components: the Candida albicans homolog of the Saccharomyces cerevisiae ++Sec20 protein is N terminally truncated, and its levels determine antifungal drug resistance and growthY Weber
Institut fur Mikrobiologie, Heinrich Heine Universitat, D 40225 Dusseldorf, Germany
J Bacteriol 183:46-54. 2001..cerevisiae, but the lack of the N-terminal domain and the apparent absence of a close TIP20 homolog in the C. albicans genome also indicate a considerable diversity in mechanisms of retrograde vesicle traffic in eukaryotes...