Dorothea Gadzicki

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. pmc Genetic testing for familial/hereditary breast cancer-comparison of guidelines and recommendations from the UK, France, the Netherlands and Germany
    Dorothea Gadzicki
    Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany
    J Community Genet 2:53-69. 2011
  2. pmc Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers
    Antonis C Antoniou
    Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Worts Causeway, Cambridge CB1 8RN, UK
    Breast Cancer Res 14:R33. 2012
  3. pmc Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2
    Anna Marie Mulligan
    Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, 2 Worts Causeway, Cambridge, CB1 8RN, UK
    Breast Cancer Res 13:R110. 2011
  4. doi request reprint Histopathological criteria and selection algorithms for BRCA1 genetic testing
    Dorothea Gadzicki
    Institute of Cell and Molecular Pathology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Cancer Genet Cytogenet 189:105-11. 2009
  5. ncbi request reprint Jacobsen syndrome and Beckwith-Wiedemann syndrome caused by a parental pericentric inversion inv(11)(p15q24)
    D Gadzicki
    Institute of Cell and Molecular Pathology, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Ann Hum Genet 70:958-64. 2006
  6. ncbi request reprint Fluorescence in situ hybridization reveals closely correlated results in cytological and histological specimens of hematological neoplasias compared to conventional cytogenetics
    Heidrun Gerr
    Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany
    Pathobiology 73:271-9. 2006
  7. doi request reprint Recurrent involvement of heterochromatic regions in multiple myeloma-a multicolor FISH study
    Kathrin Lange
    Institute of Cell and Molecular Pathology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Leuk Res 34:1002-6. 2010
  8. ncbi request reprint Standardised fluorescence in situ hybridisation in cytological and histological specimens
    Ludwig Wilkens
    Institute of Cell and Molecular Pathology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Virchows Arch 447:586-92. 2005
  9. doi request reprint No evidence for breast cancer susceptibility associated with variants of BRD7, a component of p53 and BRCA1 pathways
    Judith Penkert
    Institute of Cell and Molecular Pathology, Hannover Medical School, Carl Neuberg Strasse 1, Hannover, Germany
    Fam Cancer 11:601-6. 2012
  10. ncbi request reprint BCR-ABL gene amplification and overexpression in a patient with chronic myeloid leukemia treated with imatinib
    Dorothea Gadzicki
    Institute of Cell and Molecular Pathology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Cancer Genet Cytogenet 159:164-7. 2005

Collaborators

Detail Information

Publications14

  1. pmc Genetic testing for familial/hereditary breast cancer-comparison of guidelines and recommendations from the UK, France, the Netherlands and Germany
    Dorothea Gadzicki
    Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany
    J Community Genet 2:53-69. 2011
    ..New evidence is usually slowly integrated into the guidelines. An exchange process towards the harmonization of the guidelines will ensure high quality health care across Europe...
  2. pmc Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers
    Antonis C Antoniou
    Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Worts Causeway, Cambridge CB1 8RN, UK
    Breast Cancer Res 14:R33. 2012
    ..2)...
  3. pmc Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2
    Anna Marie Mulligan
    Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, 2 Worts Causeway, Cambridge, CB1 8RN, UK
    Breast Cancer Res 13:R110. 2011
    ..It is currently unknown how these alleles are associated with different breast cancer subtypes in BRCA1 and BRCA2 mutation carriers defined by estrogen (ER) or progesterone receptor (PR) status of the tumour...
  4. doi request reprint Histopathological criteria and selection algorithms for BRCA1 genetic testing
    Dorothea Gadzicki
    Institute of Cell and Molecular Pathology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Cancer Genet Cytogenet 189:105-11. 2009
    ..001 for G3), ER negativity (P = 0.0075), Ki67 > or = 65% (P = 0.0039), and triple negativity (i.e., ER(-), PR(-), Her2/neu(-)) (P = 0.0019) between tumors of mutation carriers and noncarriers...
  5. ncbi request reprint Jacobsen syndrome and Beckwith-Wiedemann syndrome caused by a parental pericentric inversion inv(11)(p15q24)
    D Gadzicki
    Institute of Cell and Molecular Pathology, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Ann Hum Genet 70:958-64. 2006
    ....
  6. ncbi request reprint Fluorescence in situ hybridization reveals closely correlated results in cytological and histological specimens of hematological neoplasias compared to conventional cytogenetics
    Heidrun Gerr
    Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany
    Pathobiology 73:271-9. 2006
    ..However, up to now, there has been no study comparing two main sources of diagnostic material, i.e. bone marrow aspirates and trephine biopsies. We therefore analyzed these materials by FISH in comparison with CBA...
  7. doi request reprint Recurrent involvement of heterochromatic regions in multiple myeloma-a multicolor FISH study
    Kathrin Lange
    Institute of Cell and Molecular Pathology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Leuk Res 34:1002-6. 2010
    ..These chromosome aberrations were generated by breaks in heterochromatic regions indicating an increased breakage of these regions, which may predispose to the generation of chromosome aberrations in multiple myeloma...
  8. ncbi request reprint Standardised fluorescence in situ hybridisation in cytological and histological specimens
    Ludwig Wilkens
    Institute of Cell and Molecular Pathology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Virchows Arch 447:586-92. 2005
    ..The protocol shown here is easy to perform and can be used with cytological and histological specimens. Moreover, with "hands on" time of less than 2 h, FISH can also be used for daily routine purposes...
  9. doi request reprint No evidence for breast cancer susceptibility associated with variants of BRD7, a component of p53 and BRCA1 pathways
    Judith Penkert
    Institute of Cell and Molecular Pathology, Hannover Medical School, Carl Neuberg Strasse 1, Hannover, Germany
    Fam Cancer 11:601-6. 2012
    ..However, further analyses in larger cohorts of women with hereditary breast cancer should clarify the role of BRD7 in breast cancer predisposition...
  10. ncbi request reprint BCR-ABL gene amplification and overexpression in a patient with chronic myeloid leukemia treated with imatinib
    Dorothea Gadzicki
    Institute of Cell and Molecular Pathology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Cancer Genet Cytogenet 159:164-7. 2005
    ..We give further evidence that the genomic BCR-ABL amplification results in an increased level of BCR-ABL transcript linking two potent mechanisms of resistance against imatinib treatment...
  11. doi request reprint Comprehensive genetic and functional characterization of IPH-926: a novel CDH1-null tumour cell line from human lobular breast cancer
    Matthias Christgen
    Institute of Pathology, Hannover Medical School, 30625 Hannover, Germany
    J Pathol 217:620-32. 2009
    ..In summary, IPH-926 significantly extends the biological spectrum of the established breast cancer cell lines and will facilitate functional analyses of genuine human ILBC cells in vitro and in vivo...
  12. pmc Breast cancer susceptibility: current knowledge and implications for genetic counselling
    Tim Ripperger
    Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany
    Eur J Hum Genet 17:722-31. 2009
    ....
  13. doi request reprint Novel CHD7 mutations contributing to the mutation spectrum in patients with CHARGE syndrome
    Kathrin Wessels
    Institute of Human Genetics, Hannover Medical School, Hannover, Germany
    Eur J Med Genet 53:280-5. 2010
    ..The mutation detection rate in this study was 44.4% in patients with a clinically established or suspected diagnosis of CHARGE syndrome...
  14. ncbi request reprint Tourette syndrome is not caused by mutations in the central cannabinoid receptor (CNR1) gene
    Dorothea Gadzicki
    Institute of Human Genetics, Hannover Medical School, Hannover, Germany
    Am J Med Genet B Neuropsychiatr Genet 127:97-103. 2004
    ..We conclude that genetic variations of the CNR1 gene are not a plausible explanation for the clinically observed relation between the cannabinoid system and TS...