Genomes and Genes
Affiliation: Hannover Medical School
- Genome-wide transcriptional profiling of mononuclear phagocytes recruited to mouse lungs in response to alveolar challenge with the TLR2 agonist Pam3CSK4Maciej Cabanski
Dept of Internal Medicine, Division of Pulmonary and Critical Care Medicine and Infectious Diseases, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
Am J Physiol Lung Cell Mol Physiol 297:L608-18. 2009..Collectively, our in vivo study identifies genetic programs by which alveolar recruited mononuclear phagocytes may contribute to the development and termination of pneumonia caused by gram-positive bacteria...
- PKR regulates TLR2/TLR4-dependent signaling in murine alveolar macrophagesMaciej Cabanski
University of Giessen Lung Center, Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine and Infectious Diseases, Justus Liebig University, Klinikstrasse 36, Giessen 35392, Germany
Am J Respir Cell Mol Biol 38:26-31. 2008..Collectively, these results indicate that functional PKR is critically involved in inflammatory responses of primary AM to gram-positive as well as gram-negative bacterial cell wall components...
- Monocyte/macrophage lineage commitment and distribution are affected by the lack of regulatory T cells in scurfy miceJelena Skuljec
Department of Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany
Eur J Immunol 46:1656-68. 2016..Our findings illustrate that deregulated myelopoiesis in Sf mice is mainly caused by the inflammatory reaction resulting from the lack of Treg cells. ..
- Enforced expression of miR-125b affects myelopoiesis by targeting multiple signaling pathwaysEwa Surdziel
Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
Blood 117:4338-48. 2011..These data demonstrate coordinated regulation of several signaling pathways by miR-125b linked to distinct phenotypes in myeloid cells...