Affiliation: GSF-National Research Center for Environment and Health
- Genomewide scans of complex human diseases: true linkage is hard to findJ Altmuller
Institute of Epidemiology, GSF corrected National Research Center for Environment and Health, Neuherberg, Germany
Am J Hum Genet 69:936-50. 2001..Positional cloning based on whole-genome screens in complex human disease has proved more difficult than originally had been envisioned; detection of linkage and positional cloning of specific disease-susceptibility loci remains elusive...
- Single nucleotide polymorphism screening and association analysis--exclusion of integrin beta 7 and vitamin D receptor (chromosome 12q) as candidate genes for asthmaC Vollmert
Institute of Epidemiology, GSF National Research Center for Environment and Health, 85764 Neuherberg, Germany
Clin Exp Allergy 34:1841-50. 2004....
- Asthma is associated with single-nucleotide polymorphisms in ADAM33M Werner
Institute of Epidemiology, GSF National Research Center for Environment and Health, Ingolstaedter Landstrasse, Neuherberg, Germany
Clin Exp Allergy 34:26-31. 2004..The ADAM33 gene has recently been associated with asthma and bronchial hyper-reactivity. It codes for a disintegrin and metalloproteinase that triggers intra- and extracellular signalling by protein shedding...