Twan Lammers

Summary

Affiliation: German Cancer Research Center
Country: Germany

Publications

  1. ncbi request reprint Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers
    Twan Lammers
    Department of Innovative Cancer Diagnosis and Therapy, Clinical Cooperation Unit Radiotherapeutic Oncology, German Cancer Research Center, Heidelberg
    J Control Release 110:103-18. 2005
  2. ncbi request reprint Synthesis and characterization of HE-24.8: a polymeric contrast agent for magnetic resonance angiography
    Fabian Kiessling
    Division of Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Germany
    Bioconjug Chem 17:42-51. 2006
  3. ncbi request reprint Effect of radiotherapy and hyperthermia on the tumor accumulation of HPMA copolymer-based drug delivery systems
    Twan Lammers
    Department of Innovative Cancer Diagnosis and Therapy, Clinical Cooperation Unit Radiotherapeutic Oncology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    J Control Release 117:333-41. 2007
  4. doi request reprint Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers
    Twan Lammers
    Department of Innovative Cancer Diagnosis and Therapy, DKFZ Heidelberg, German Cancer Research Center, Germany
    Biomaterials 30:3466-75. 2009
  5. pmc Image-guided and passively tumour-targeted polymeric nanomedicines for radiochemotherapy
    T Lammers
    Department of Innovative Cancer Diagnosis and Therapy, Clinical Cooperation Unit Radiotherapeutic Oncology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Br J Cancer 99:900-10. 2008
  6. ncbi request reprint Role of type 2C protein phosphatases in growth regulation and in cellular stress signaling
    Twan Lammers
    Department of Innovative Cancer Diagnosis and Therapy, German Cancer Research Center, Heidelberg, Germany
    Crit Rev Biochem Mol Biol 42:437-61. 2007
  7. pmc Role of PP2Calpha in cell growth, in radio- and chemosensitivity, and in tumorigenicity
    Twan Lammers
    Department of Innovative Cancer Diagnosis and Therapy, Clinical Cooperation Unit Radiotherapeutic Oncology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Mol Cancer 6:65. 2007
  8. pmc Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymer-based drug delivery systems
    Twan Lammers
    Clinical Cooperation Unit Radiotherapeutic Oncology, Department of Innovative Cancer Diagnosis and Therapy, German Cancer Research Center, Heidelberg 69120, Germany
    Neoplasia 8:788-95. 2006
  9. ncbi request reprint Specific targeting of tumor angiogenesis by RGD-conjugated ultrasmall superparamagnetic iron oxide particles using a clinical 1.5-T magnetic resonance scanner
    Chunfu Zhang
    Junior Group Molecular Imaging, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Cancer Res 67:1555-62. 2007
  10. pmc BioShuttle mobility in living cells studied with high-resolution FCS & CLSM methodologies
    Klaus Braun
    Dept of Imaging and Radiooncology, German Cancer Research Center, Im Neuenheimer Feld 280, Heidelberg, Germany
    Int J Med Sci 9:339-52. 2012

Detail Information

Publications11

  1. ncbi request reprint Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers
    Twan Lammers
    Department of Innovative Cancer Diagnosis and Therapy, Clinical Cooperation Unit Radiotherapeutic Oncology, German Cancer Research Center, Heidelberg
    J Control Release 110:103-18. 2005
    ....
  2. ncbi request reprint Synthesis and characterization of HE-24.8: a polymeric contrast agent for magnetic resonance angiography
    Fabian Kiessling
    Division of Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Germany
    Bioconjug Chem 17:42-51. 2006
    ..8; however, contrast of vessels was higher in HE-24.8-enhanced scans. HE-24.8 is considered a macromolecular contrast agent highly suited for experimental MR studies...
  3. ncbi request reprint Effect of radiotherapy and hyperthermia on the tumor accumulation of HPMA copolymer-based drug delivery systems
    Twan Lammers
    Department of Innovative Cancer Diagnosis and Therapy, Clinical Cooperation Unit Radiotherapeutic Oncology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    J Control Release 117:333-41. 2007
    ....
  4. doi request reprint Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers
    Twan Lammers
    Department of Innovative Cancer Diagnosis and Therapy, DKFZ Heidelberg, German Cancer Research Center, Germany
    Biomaterials 30:3466-75. 2009
    ....
  5. pmc Image-guided and passively tumour-targeted polymeric nanomedicines for radiochemotherapy
    T Lammers
    Department of Innovative Cancer Diagnosis and Therapy, Clinical Cooperation Unit Radiotherapeutic Oncology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Br J Cancer 99:900-10. 2008
    ..Based on these findings, and on the fact that its principles are likely broadly applicable, we propose carrier-based radiochemotherapy as a novel concept for treating advanced solid malignancies...
  6. ncbi request reprint Role of type 2C protein phosphatases in growth regulation and in cellular stress signaling
    Twan Lammers
    Department of Innovative Cancer Diagnosis and Therapy, German Cancer Research Center, Heidelberg, Germany
    Crit Rev Biochem Mol Biol 42:437-61. 2007
    ..Based on the vast amount of experimental evidence obtained thus far, it therefore seems justified to conclude that type 2C protein phosphatases are important physiological regulators of cell growth and of cellular stress signaling...
  7. pmc Role of PP2Calpha in cell growth, in radio- and chemosensitivity, and in tumorigenicity
    Twan Lammers
    Department of Innovative Cancer Diagnosis and Therapy, Clinical Cooperation Unit Radiotherapeutic Oncology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Mol Cancer 6:65. 2007
    ..By comparing the growth of tumors established from both types of cells, we also evaluated the involvement of PP2Calpha in tumorigenesis...
  8. pmc Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymer-based drug delivery systems
    Twan Lammers
    Clinical Cooperation Unit Radiotherapeutic Oncology, Department of Innovative Cancer Diagnosis and Therapy, German Cancer Research Center, Heidelberg 69120, Germany
    Neoplasia 8:788-95. 2006
    ..Based on these findings, we propose intratumorally injected carrier-based chemotherapy as an interesting alternative to routinely used chemotherapy regimens and routes of administration...
  9. ncbi request reprint Specific targeting of tumor angiogenesis by RGD-conjugated ultrasmall superparamagnetic iron oxide particles using a clinical 1.5-T magnetic resonance scanner
    Chunfu Zhang
    Junior Group Molecular Imaging, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Cancer Res 67:1555-62. 2007
    ..Furthermore, these molecular MR imaging probes are capable of distinguishing tumors differing in the degree of alpha(v)beta(3) integrin expression and in their angiogenesis profile even when using a clinical 1.5-T MR scanner...
  10. pmc BioShuttle mobility in living cells studied with high-resolution FCS & CLSM methodologies
    Klaus Braun
    Dept of Imaging and Radiooncology, German Cancer Research Center, Im Neuenheimer Feld 280, Heidelberg, Germany
    Int J Med Sci 9:339-52. 2012
    ..The modular design of BioShuttle-based formulations results in a multi-faceted field of applications, also as a theranostic tool...
  11. doi request reprint Riboflavin carrier protein-targeted fluorescent USPIO for the assessment of vascular metabolism in tumors
    Jabadurai Jayapaul
    Department of Experimental Molecular Imaging, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany
    Biomaterials 33:8822-9. 2012
    ....