Jurgen Gallinat

Summary

Country: Germany

Publications

  1. ncbi request reprint Frontal and temporal dysfunction of auditory stimulus processing in schizophrenia
    Jurgen Gallinat
    Department of Psychiatry, Free University, Berlin, Germany
    Neuroimage 17:110-27. 2002
  2. doi request reprint Switching schizophrenia patients from typical neuroleptics to aripiprazole: effects on working memory dependent functional activation
    Florian Schlagenhauf
    Department of Psychiatry, Charite Universitaetsmedizin Berlin, Campus Mitte, Germany
    Schizophr Res 118:189-200. 2010
  3. doi request reprint Reduction of auditory event-related P300 amplitude in subjects with at-risk mental state for schizophrenia
    Seza Ozgurdal
    Department of Psychiatry, Ruhr University Bochum, LWL University Hospital, Germany
    Schizophr Res 105:272-8. 2008
  4. ncbi request reprint Dysfunction of ventral striatal reward prediction in schizophrenic patients treated with typical, not atypical, neuroleptics
    Georg Juckel
    Department of Psychiatry, Charite University Medical Center, Campus Charité Mitte CCM, Schumannstr 20 21, Berlin 10117, Germany
    Psychopharmacology (Berl) 187:222-8. 2006
  5. doi request reprint Neurocognitive impairments in non-deprived smokers--results from a population-based multi-center study on smoking-related behavior
    Michael Wagner
    Department of Psychiatry, University of Bonn, Germany
    Addict Biol 18:752-61. 2013
  6. doi request reprint Met carriers of BDNF Val66Met genotype show increased N-acetylaspartate concentration in the anterior cingulate cortex
    Jurgen Gallinat
    Department of Psychiatry and Psychotherapy, Charite, University Medicine Berlin, Campus Mitte, Berlin, Germany
    Neuroimage 49:767-71. 2010
  7. ncbi request reprint Cortical hypoactivation during resting EEG in schizophrenics but not in depressives and schizotypal subjects as revealed by low resolution electromagnetic tomography (LORETA)
    Susanne Mientus
    Department of Psychiatry, Free University of Berlin, Berlin, Germany
    Psychiatry Res 116:95-111. 2002
  8. doi request reprint Common structural correlates of trait impulsiveness and perceptual reasoning in adolescence
    Christina Schilling
    Department of Psychiatry and Psychotherapy, Charité University Medicine Campus Mitte, Berlin, Germany
    Hum Brain Mapp 34:374-83. 2013
  9. ncbi request reprint Association of human hippocampal neurochemistry, serotonin transporter genetic variation, and anxiety
    Jurgen Gallinat
    Clinic for Psychiatry and Psychotherapy, Charite University Medicine, Berlin, Germany
    Neuroimage 26:123-31. 2005
  10. ncbi request reprint No association of a functional polymorphism in the serotonin transporter gene promoter and anxiety-related personality traits
    Undine E Lang
    Department of Psychiatry, Benjamin Franklin Medical School, Free University of Berlin, Germany
    Neuropsychobiology 49:182-4. 2004

Detail Information

Publications75

  1. ncbi request reprint Frontal and temporal dysfunction of auditory stimulus processing in schizophrenia
    Jurgen Gallinat
    Department of Psychiatry, Free University, Berlin, Germany
    Neuroimage 17:110-27. 2002
    ..This would be in line with the notion that attention deficits in schizophrenia involve an extended cortical network...
  2. doi request reprint Switching schizophrenia patients from typical neuroleptics to aripiprazole: effects on working memory dependent functional activation
    Florian Schlagenhauf
    Department of Psychiatry, Charite Universitaetsmedizin Berlin, Campus Mitte, Germany
    Schizophr Res 118:189-200. 2010
    ..However, little is known about specific medication effects on the modulation of frontal activation during WM performance...
  3. doi request reprint Reduction of auditory event-related P300 amplitude in subjects with at-risk mental state for schizophrenia
    Seza Ozgurdal
    Department of Psychiatry, Ruhr University Bochum, LWL University Hospital, Germany
    Schizophr Res 105:272-8. 2008
    ..e. before a manifestation of full-blown psychosis, and that these changes seem to have a progressive course from prodromal to chronic state of schizophrenia as assumed in this cross-sectional study...
  4. ncbi request reprint Dysfunction of ventral striatal reward prediction in schizophrenic patients treated with typical, not atypical, neuroleptics
    Georg Juckel
    Department of Psychiatry, Charite University Medical Center, Campus Charité Mitte CCM, Schumannstr 20 21, Berlin 10117, Germany
    Psychopharmacology (Berl) 187:222-8. 2006
    ..Dysfunction of the dopaminergic reward system may contribute to negative symptoms in schizophrenia...
  5. doi request reprint Neurocognitive impairments in non-deprived smokers--results from a population-based multi-center study on smoking-related behavior
    Michael Wagner
    Department of Psychiatry, University of Bonn, Germany
    Addict Biol 18:752-61. 2013
    ..The independence of these deficits from consumption intensity may argue for an a priori deficit of some cognitive abilities in smokers. These specific deficits may constitute intermediate phenotypes for genetic research on nicotine use...
  6. doi request reprint Met carriers of BDNF Val66Met genotype show increased N-acetylaspartate concentration in the anterior cingulate cortex
    Jurgen Gallinat
    Department of Psychiatry and Psychotherapy, Charite, University Medicine Berlin, Campus Mitte, Berlin, Germany
    Neuroimage 49:767-71. 2010
    ..We hypothesize that higher NAA levels in the ACC might contribute to the protection of Met allele carriers against major psychiatric disorders as schizophrenia and bipolar disorder...
  7. ncbi request reprint Cortical hypoactivation during resting EEG in schizophrenics but not in depressives and schizotypal subjects as revealed by low resolution electromagnetic tomography (LORETA)
    Susanne Mientus
    Department of Psychiatry, Free University of Berlin, Berlin, Germany
    Psychiatry Res 116:95-111. 2002
    ..The results are discussed within a neurophysiological and methodological framework...
  8. doi request reprint Common structural correlates of trait impulsiveness and perceptual reasoning in adolescence
    Christina Schilling
    Department of Psychiatry and Psychotherapy, Charité University Medicine Campus Mitte, Berlin, Germany
    Hum Brain Mapp 34:374-83. 2013
    ..This study investigates whether there are common structural cerebral correlates of trait impulsiveness and cognitive functioning in a large sample of healthy adolescents from the IMAGEN project...
  9. ncbi request reprint Association of human hippocampal neurochemistry, serotonin transporter genetic variation, and anxiety
    Jurgen Gallinat
    Clinic for Psychiatry and Psychotherapy, Charite University Medicine, Berlin, Germany
    Neuroimage 26:123-31. 2005
    ....
  10. ncbi request reprint No association of a functional polymorphism in the serotonin transporter gene promoter and anxiety-related personality traits
    Undine E Lang
    Department of Psychiatry, Benjamin Franklin Medical School, Free University of Berlin, Germany
    Neuropsychobiology 49:182-4. 2004
    ..f. = 2) in all subjects. Given the small effect of this 5-HTT polymorphism on behaviour in previous studies, a lack of significant genotype differences in these tests could be due to considerable individual variability in these measures...
  11. doi request reprint Effects of acute oral Delta9-tetrahydrocannabinol and standardized cannabis extract on the auditory P300 event-related potential in healthy volunteers
    Patrik Roser
    Department of Psychiatry, Ruhr University Bochum, Bochum, Germany
    Eur Neuropsychopharmacol 18:569-77. 2008
    ..It can be speculated whether the lack of effect of CBD may be due to an insufficient dose used or to an involvement of neurotransmitter systems in P300 generation which are not influenced by CBD...
  12. doi request reprint Catechol-O-methyltransferase val158met genotype influences neural processing of reward anticipation
    Katharina Schmack
    Department of Psychiatry, Charite University Medicine, Chariteplatz 1, 10117 Berlin, Germany
    Neuroimage 42:1631-8. 2008
    ..Current evidence and our results are compatible with an interpretation that construes this effect of COMT genotype on striatal reactivity as a result of a cortico-striatal interaction...
  13. doi request reprint Psychomotor performance in relation to acute oral administration of Delta9-tetrahydrocannabinol and standardized cannabis extract in healthy human subjects
    Patrik Roser
    Department of Psychiatry, Ruhr University Bochum, Bochum, Germany
    Eur Arch Psychiatry Clin Neurosci 259:284-92. 2009
    ..This result may be due to functional changes involving GABAergic and glutamatergic neurotransmission within the corpus callosum...
  14. doi request reprint The German multi-centre study on smoking-related behavior-description of a population-based case-control study
    Annette Lindenberg
    Department of Psychiatry, Heinrich Heine University Dusseldorf, Germany
    Addict Biol 16:638-53. 2011
    ..Study design and major population characteristics with emphasis on risk prediction of smoking status were presented in this paper...
  15. ncbi request reprint P300 subcomponents in obsessive-compulsive disorder
    Paraskevi Mavrogiorgou
    Department of Psychiatry, Section of Clinical Neurophysiology and Outpatient Clinic for Obsessive Compulsive Disorder, Ludwig Maximilians University Munich, Germany
    J Psychiatr Res 36:399-406. 2002
    ....
  16. ncbi request reprint Persistent dysfunctional frontal lobe activation in former smokers
    Andres Neuhaus
    Department of Psychiatry and Psychotherapy, Charite University Medicine, Campus Benjamin Franklin, Berlin, Germany
    Psychopharmacology (Berl) 186:191-200. 2006
    ..However, it is largely unknown if cerebral dysfunctions are reversible or persist during long term abstinence...
  17. ncbi request reprint Is the loudness dependence of auditory evoked potentials modulated by the selective serotonin reuptake inhibitor citalopram in healthy subjects?
    Idun Uhl
    Department of Psychiatry and Psychotherapy, Charite, Campus Mitte, Berlin, Germany
    Hum Psychopharmacol 21:463-71. 2006
    ..The result underlines that the acceptance of LDAEP as a marker of central serotonergic function still needs further discussion...
  18. doi request reprint Serotonin transporter promoter polymorphism and dopaminergic sensitivity in alcoholics
    Henning Budde
    Department of Movement and Training Science, Institute of Sport Science, Humboldt University, Philippstrasse 13, 10115, Berlin, Germany
    J Neural Transm (Vienna) 117:133-8. 2010
    ..It is hypothesized that the reduction of sensitivity of the central DA receptors in alcoholics with the L/L genotype might be due to their higher vulnerability to the neurotoxic effects of chronic alcohol consumption than the S carriers...
  19. doi request reprint COMT Val108/158Met genotype modulates human sensory gating
    Tomislav Majic
    Clinic for Psychiatry and Psychotherapy, Charite University Medicine, Campus Mitte, Berlin, Germany
    Neuroimage 55:818-24. 2011
    ..It is however unclear if COMT genotype as a predictor of prefrontal efficiency modulates sensory gating on the level of the auditory cortex, i.e. the gating of the auditory evoked P50 and N100 components...
  20. doi request reprint Serotonergic dysfunction in the prodromal, first-episode and chronic course of schizophrenia as assessed by the loudness dependence of auditory evoked activity
    Yehonala Gudlowski
    Department of Psychiatry and Psychotherapy, Charite, University Medicine of Berlin, Campus Mitte, Berlin, Germany
    Schizophr Res 109:141-7. 2009
    ..A weak LDAEP may therefore represent a vulnerability marker rather than an expression of illness progression...
  21. ncbi request reprint Polymorphisms in the N-methyl-D-aspartate receptor 1 and 2B subunits are associated with alcoholism-related traits
    Catrin Wernicke
    Department of Clinical Neurobiology, University Hospital Benjamin Franklin, Free University of Berlin, Berlin, Germany
    Biol Psychiatry 54:922-8. 2003
    ..This study examined the hypothesis that allelic variants of the ionotropic glutamatergic N-methyl-D-aspartate receptor (NMDAR) are associated with vulnerability to alcoholism and some related traits...
  22. ncbi request reprint Loudness dependence of auditory evoked potentials is not associated with polymorphisms or haplotypes in the serotonin transporter gene in a community-based sample of German healthy volunteers
    Georg Juckel
    Department of Psychiatry, Ruhr University Bochum, Germany
    Psychiatry Res 153:183-7. 2007
    ..We speculate that the LD endophenotype depends more on genetic variations in components of the serotonergic system controlling release than on those controlling the uptake mechanism...
  23. doi request reprint Brain grey matter deficits in smokers: focus on the cerebellum
    Simone Kühn
    Charite University Medicine, St Hedwig Krankenhaus, Clinic for Psychiatry and Psychotherapy, Berlin, Germany
    Brain Struct Funct 217:517-22. 2012
    ..Of note, the dependence-related magnitude of the volume deficit may support the notion that the cerebellum is substantially involved in core mechanisms of drug dependence...
  24. doi request reprint Switching schizophrenia patients from typical neuroleptics to olanzapine: effects on BOLD response during attention and working memory
    Florian Schlagenhauf
    Department of Psychiatry, Charite Universitaetsmedizin Berlin, Campus Mitte, Germany
    Eur Neuropsychopharmacol 18:589-99. 2008
    ..However, medication status had influences on the activation during attentional task (0-back), emphasizing the importance of baseline selection in pharmacological fMRI studies...
  25. doi request reprint Oxytocin and oxytocin receptor gene polymorphisms and risk for schizophrenia: a case-control study
    Christiane Montag
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Mitte, Berlin, Germany
    World J Biol Psychiatry 14:500-8. 2013
    ..This study aims to determine a possible contribution of OXT and OXTR genetic variations to schizophrenia susceptibility...
  26. doi request reprint Effects of age and sex on the concentrations of glutamate and glutamine in the human brain
    Sven Hädel
    Department of Psychiatry and Psychotherapy, Psychiatric University Hospital St Hedwig, Charite University Medicine Berlin, Campus Mitte, Berlin, Germany
    J Magn Reson Imaging 38:1480-7. 2013
    ..Exploratory examinations of other brain metabolites were also conducted...
  27. doi request reprint Neural correlates of impaired volitional action control in schizophrenia patients
    Julia Bender
    Department of Psychology, Humboldt Universitat zu Berlin, Berlin, Germany
    Psychophysiology 50:872-84. 2013
    ....
  28. ncbi request reprint Reduced oscillatory gamma-band responses in unmedicated schizophrenic patients indicate impaired frontal network processing
    Jurgen Gallinat
    Clinic for Psychiatry and Psychotherapy, Humboldt University, Berlin, Germany
    Clin Neurophysiol 115:1863-74. 2004
    ..This is the first investigation of oscillatory activations in the gamma-band in an auditory oddball paradigm in unmedicated schizophrenic patients...
  29. doi request reprint Reduction of cerebellar grey matter in Crus I and II in schizophrenia
    Simone Kühn
    Clinic for Psychiatry and Psychotherapy, St Hedwig Krankenhaus, Charite University Medicine, Campus Mitte, Berlin, Germany
    Brain Struct Funct 217:523-9. 2012
    ..The failure of conventional VBM to detect such effects suggests that previous studies might have underestimated the importance of cerebellar structural deficits in schizophrenia...
  30. ncbi request reprint Association of the dopamine D2 receptor gene with alcohol dependence: haplotypes and subgroups of alcoholics as key factors for understanding receptor function
    Adrian Kraschewski
    Charite Universitatsmedizin Berlin, Klinik für Psychiatrie and Psychotherapie, Campus Benjamin Franklin, Berlin, Germany
    Pharmacogenet Genomics 19:513-27. 2009
    ..We examined the hypothesis that haplotypes composed of polymorphisms, associated with reduced receptor expression, are more frequent in alcoholics compared with healthy individuals...
  31. doi request reprint Association between a cannabinoid receptor gene (CNR1) polymorphism and cannabinoid-induced alterations of the auditory event-related P300 potential
    Andreas M Stadelmann
    Department of Psychiatry and Psychotherapy, Charite University Hospital Berlin, Berlin, Germany
    Neurosci Lett 496:60-4. 2011
    ..Moreover, it appears that variations within CNR1 may differentially alter the sensitivity to the acute effects of cannabinoids on P300 generation in healthy subjects...
  32. ncbi request reprint Abnormal hippocampal neurochemistry in smokers: evidence from proton magnetic resonance spectroscopy at 3 T
    Jurgen Gallinat
    Klinik fur Psychiatrie und Psychotherapie, Charite Universitatsmedizin, Campus Mitte PUK Charité SHK, Berlin, Germany
    J Clin Psychopharmacol 27:80-4. 2007
    ..In this study, proton magnetic resonance spectroscopy was used to assess the effects of chronic smoking on neuronal integrity of the hippocampus and anterior cingulate cortex (ACC)...
  33. ncbi request reprint Pharmacogenetic insights to monoaminergic dysfunction in alcohol dependence
    Andreas Heinz
    Department of Psychiatry, Campus Charite Mitte, Charite University Medicine Berlin, Schumannstrasse 20 21, 10117 Berlin, Germany
    Psychopharmacology (Berl) 174:561-70. 2004
    ..The severity and time-course of recovery of these neuroadaptive changes may depend on the genetic constitution of monoamine transporters and receptors and contribute to the relapse risk of alcoholics...
  34. ncbi request reprint Examining the gateway to the limbic system with diffusion tensor imaging: the perforant pathway in dementia
    Peter Kalus
    Department of Psychiatry, Charite University Medicine, Campus Mitte, Berlin, Germany
    Neuroimage 30:713-20. 2006
    ..DTI of medial temporal brain regions is a promising non-invasive tool for the in vivo diagnosis of the early/preclinical stages of AD...
  35. ncbi request reprint Serotonergic dysfunction in schizophrenia assessed by the loudness dependence measure of primary auditory cortex evoked activity
    Georg Juckel
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Schizophr Res 64:115-24. 2003
    ..These results suggest that the loudness dependence of primary auditory cortex evoked activity is well suitable to assess serotonergic dysfunction in schizophrenia...
  36. ncbi request reprint Acute effects of Delta9-tetrahydrocannabinol and standardized cannabis extract on the auditory evoked mismatch negativity
    Georg Juckel
    Department of Psychiatry, University Hospital Charite, Berlin, Germany
    Schizophr Res 97:109-17. 2007
    ..This effect may be relevant for auditory cortex activity in particular because only MMN amplitudes at the central, but not at the frontal electrodes were enhanced under cannabis...
  37. ncbi request reprint Allelic variants of the functional promoter polymorphism of the human serotonin transporter gene is associated with auditory cortical stimulus processing
    Jurgen Gallinat
    Department of Psychiatry, Free University of Berlin, Eschenallee 3, 14050 Berlin, Germany
    Neuropsychopharmacology 28:530-2. 2003
    ..The LD may serve as endophenotype in human serotonin research...
  38. doi request reprint Frontal glutamate and reward processing in adolescence and adulthood
    Tobias Gleich
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Brain Struct Funct 220:3087-99. 2015
    ..This fronto-limbic coupling may represent a vulnerability factor for psychiatric disorders starting in adolescence but not in adulthood. ..
  39. doi request reprint Automatic approach bias towards smoking cues is present in smokers but not in ex-smokers
    Corinde E Wiers
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Berlin, Germany
    Psychopharmacology (Berl) 229:187-97. 2013
    ..Drug-addicted individuals show automatic approach tendencies towards drug-related cues, i.e., an approach bias (ApB). Nevertheless, little is known about ApB in tobacco smokers and about the presence of ApB after smoking abstinence...
  40. pmc Association between oxytocin receptor gene polymorphisms and self-rated 'empathic concern' in schizophrenia
    Christiane Montag
    Department of Psychiatry and Psychotherapy, Charite Campus Mitte, Charité University Medicine Berlin Charité Universitätsmedizin Berlin, Berlin, Germany
    PLoS ONE 7:e51882. 2012
    ..Our preliminary findings support hypotheses about an involvement of OXTR rs2254298 in emotional empathy in schizophrenic and healthy individuals, warranting independent replication...
  41. doi request reprint Interaction of hippocampal volume and N-acetylaspartate concentration deficits in schizophrenia: a combined MRI and 1H-MRS study
    Andreas Arthur Klär
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Mitte, Berlin, Germany
    Neuroimage 53:51-7. 2010
    ..However, the possible interaction between regional NAA reduction and volume deficits has been targeted only marginally in previous investigations...
  42. ncbi request reprint Association of the G1947A COMT (Val(108/158)Met) gene polymorphism with prefrontal P300 during information processing
    Jurgen Gallinat
    Laboratory for Clinical Psychophysiology, Department of Psychiatry, Free University, Berlin, Germany and National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    Biol Psychiatry 54:40-8. 2003
    ..It was predicted that homozygous Met allele carriers have a lower frontal P300 amplitude...
  43. ncbi request reprint The relationship between reaction time, error rate and anterior cingulate cortex activity
    Christoph Mulert
    Laboratory for Clinical Psychophysiology, Department of Psychiatry, Free University, Berlin, Germany
    Int J Psychophysiol 47:175-83. 2003
    ..This finding suggests that increased ACC activity is associated with a gain in reaction speed at the expense of correctness and is discussed in the context of current concepts about the role of the ACC in cognitive functions...
  44. pmc Regional patterns and clinical correlates of basal ganglia morphology in non-medicated schizophrenia
    Martina Ballmaier
    Department of Psychiatry and Psychotherapy, Charite University Medicine, Berlin, Germany
    Schizophr Res 106:140-7. 2008
    ....
  45. doi request reprint Heroin or conventional opioid maintenance? The patients' perspective
    Lena Karoline Bald
    From the Department of Psychiatry and Psychotherapy, Universitätspsych iatrie der Charité im St Hedwig Krankenhaus, Berlin, Germany
    J Addict Med 7:401-4. 2013
    ..This study focused on the question whether patients with conventional opioid maintenance treatment (COMT) would prefer a switch to heroin maintenance treatment (HMT)...
  46. doi request reprint Comparison of midlatency auditory sensory gating at short and long interstimulus intervals
    Johannes Rentzsch
    Campus Mitte, Department of Psychiatry, Charite Universitatsmedizin Berlin, Berlin, Germany
    Neuropsychobiology 58:11-8. 2008
    ..The aim of the study was to investigate whether a simple modified dual-click protocol with short interstimulus intervals elicts similar sensory gating ratios compared to the classic protocol...
  47. doi request reprint Serotonin transporter gene and adverse life events in adult ADHD
    Daniel J Muller
    Department of Psychiatry, Charite University Medicine Berlin, Campus Mitte, Berlin, Germany
    Am J Med Genet B Neuropsychiatr Genet 147:1461-9. 2008
    ..In conclusion, our data support the role of environmental factors in adult ADHD symptomatology. SERTPR may be involved in some features of the illness and act as a moderator of environmental influences in ADHD...
  48. ncbi request reprint Motorcortical excitability after electroconvulsive therapy in patients with major depressive disorder
    Malek Bajbouj
    Department of Psychiatry, Charite University Medicine Berlin, Campus Benjamin Franklin, Eschenallee 3, 14050 Berlin, Germany
    Suppl Clin Neurophysiol 56:433-40. 2003
  49. ncbi request reprint Neurophysiological effects of cannabinoids: implications for psychosis research
    Jurgen Gallinat
    Department of Psychiatry, Charite University Medicine Berlin, Campus Charite Mitte, Berlin, Germany
    Curr Pharm Des 18:4938-49. 2012
    ....
  50. doi request reprint Different aspects of theory of mind in paranoid schizophrenia: evidence from a video-based assessment
    Christiane Montag
    Charite University Medicine Berlin, Department of Psychiatry and Psychotherapy, Campus Mitte, Berlin, Germany
    Psychiatry Res 186:203-9. 2011
    ..In schizophrenic patients, negative symptoms were associated with a lack of a mental state concept, while positive symptoms like delusions were associated with 'overmentalizing', supporting respective etiological concepts of delusions...
  51. ncbi request reprint Test-retest reliability of P50, N100 and P200 auditory sensory gating in healthy subjects
    Johannes Rentzsch
    Department of Psychiatry, Charite Universitatsmedizin Berlin, Germany
    Int J Psychophysiol 67:81-90. 2008
    ..However, most studies only show a low reliability for P50 sensory gating and neither N100 nor P200 sensory gating have been sufficiently tested...
  52. pmc Prefrontal cortex glutamate correlates with mental perspective-taking
    Christiane Montag
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Mitte, Berlin, Germany
    PLoS ONE 3:e3890. 2008
    ..However, the role of the glutamate system for different dimensions of empathy has not been investigated so far...
  53. doi request reprint Gray matter abnormalities in subjects at ultra-high risk for schizophrenia and first-episode schizophrenic patients compared to healthy controls
    Henning Witthaus
    Early Recognition and Therapy Centre for Psychoses Bochum BoFit, Department of Psychiatry, Psychotherapy and Psychosomatic Medicine, Ruhr University of Bochum, Alexandrinenstrasse 1, 44791, Germany
    Psychiatry Res 173:163-9. 2009
    ..This study provides further evidence that gray matter brain volume, especially in the anterior cingulate cortex, is already reduced in the prodromal state of schizophrenia...
  54. doi request reprint P50 sensory gating and smoking in the general population
    Jürgen Brinkmeyer
    Department of Psychiatry, Heinrich Heine University Dusseldorf, Bergische Landstrasse 2, Dusseldorf, Germany
    Addict Biol 16:485-98. 2011
    ..The suitability and application of sensory P50 gating as functional biomarker with regard to genetic and pharmacological studies is discussed...
  55. doi request reprint Attentional dysfunction in abstinent long-term cannabis users with and without schizophrenia
    Johannes Rentzsch
    Charite Universitatsmedizin Berlin, Campus Mitte, Chariteplatz 1, 10117, Berlin, Germany
    Eur Arch Psychiatry Clin Neurosci 266:409-21. 2016
    ..However, cannabis use may lead to different cognitive sequelae in patients with schizophrenia and in healthy controls, possibly reflecting preexisting alterations in the endocannabinoid system in schizophrenia. ..
  56. doi request reprint Interactions between glutamate, dopamine, and the neuronal signature of response inhibition in the human striatum
    Robert C Lorenz
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Hum Brain Mapp 36:4031-40. 2015
    ..This finding stresses the importance of the dopamine-glutamate interaction for behavior and may facilitate the understanding of psychiatric disorders characterized by impaired response inhibition...
  57. doi request reprint Plasticity of hippocampal subfield volume cornu ammonis 2+3 over the course of withdrawal in patients with alcohol dependence
    Simone Kühn
    Max Planck Institute for Human Development, Center for Lifespan Psychology, Berlin, Germany
    JAMA Psychiatry 71:806-11. 2014
    ..Chronic alcoholism is associated with decreased plasticity and reduced whole hippocampal volume that could contribute to neuropsychiatric characteristics and outcome of the disease...
  58. doi request reprint Why do patients stay in opioid maintenance treatment?
    Stefan Gutwinski
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin, Berlin, Germany
    Subst Use Misuse 49:694-9. 2014
    ..We conclude that besides reduced mortality, these subjective factors may contribute to a growing number of patients in OMT. No financial or material support was received in any phase of the study. ..
  59. doi request reprint Impaired sleep quality and sleep duration in smokers-results from the German Multicenter Study on Nicotine Dependence
    Stefan Cohrs
    Department of Sleep Medicine, St Hedwig Clinic Berlin, Berlin, Germany Institute of Physiology, Sleepresearch and Clinical Chronobiology, Charite, Berlin, Germany Department of Psychiatry and Psychotherapy, Georg August University Gottingen, Gottingen, Germany
    Addict Biol 19:486-96. 2014
    ..It appears likely that smoking is a behaviourally modifiable risk factor for the occurrence of impaired SQ and short sleep duration. ..
  60. pmc Positive association of video game playing with left frontal cortical thickness in adolescents
    Simone Kühn
    Ghent University, Faculty of Psychology and Educational Sciences, Department of Experimental Psychology and Ghent Institute for Functional and Metabolic Imaging, Ghent, Belgium Clinic for Psychiatry and Psychotherapy, Charite University Medicine, St Hedwig Krankenhaus, Campus Mitte, Berlin, Germany Physikalisch Technische Bundesanstalt PTB, Berlin and Braunschweig, Germany
    PLoS ONE 9:e91506. 2014
    ..Whether or not these results represent a-priori characteristics or consequences of video gaming should be studied in future longitudinal investigations. ..
  61. doi request reprint Volitional saccades and attentional mechanisms in schizophrenia patients and healthy control subjects
    Benedikt Reuter
    Institut fur Psychologie, Humboldt Universitat zu Berlin, Berlin, Germany
    Psychophysiology 48:1333-9. 2011
    ..Unexpectedly, SZ patients had normal saccade latencies. Presumably, the expected deficit was compensated by decreased fixation-related neural activity, which was induced by the disappearance of fixation stimuli...
  62. ncbi request reprint Association of attentional network function with exon 5 variations of the CHRNA4 gene
    Georg Winterer
    Department of Psychiatry, Henirich Heine University, Duesseldorf, Germany
    Hum Mol Genet 16:2165-74. 2007
    ..If confirmed, future studies need to address what 'functional' polymorphisms are causative for the observed effects...
  63. ncbi request reprint BDNF serum concentrations in healthy volunteers are associated with depression-related personality traits
    Undine E Lang
    Clinic for Psychiatry and Psychotherapy, Charité Medicine Berlin, Campus Benjamin Franklin, Germany
    Neuropsychopharmacology 29:795-8. 2004
    ..These results provide further support for the hypothesis that BDNF may be central to the development of depressive mood states...
  64. ncbi request reprint Evidence for the importance of the human dopamine transporter gene for withdrawal symptomatology of alcoholics in a German population
    Catrin Wernicke
    Department of Clinical Neurobiology, Benjamin Franklin Medical School, Free University of Berlin, Ulmenallee 32, D 14050 Berlin, Germany
    Neurosci Lett 333:45-8. 2002
    ..032, OR = 4.707), and with an alcoholic mother (P = 0.021, OR = 5.250), compared to homozygote 10/10 controls. Our findings provide further evidence that the 3'UTR of the DAT1 gene affects vulnerability to severe alcohol withdrawal...
  65. pmc Auditory mismatch negativity and repetition suppression deficits in schizophrenia explained by irregular computation of prediction error
    Johannes Rentzsch
    Department of Psychiatry, Charite University Medicine, Berlin, Germany
    PLoS ONE 10:e0126775. 2015
    ..Both mismatch negativity (MMN) and repetition suppression (RS) measures are considered a prediction error correlates based on error detection and error minimization, respectively...
  66. doi request reprint Reduced thickness of anterior cingulate cortex in obsessive-compulsive disorder
    Simone Kühn
    Ghent University, Faculty of Psychology and Educational Sciences, Department of Experimental Psychology, Ghent Institute for Functional and Metabolic Imaging, Gent, Belgium
    Cortex 49:2178-85. 2013
    ..Structural alterations in OCD have been discussed but analysis tools focussing on specific morphometric aspects such as cortical thickness have rarely been employed...
  67. ncbi request reprint The amygdala in schizophrenia: a trimodal magnetic resonance imaging study
    Peter Kalus
    Clinic for Psychiatry and Psychotherapy, Charite University Medicine, Campus Mitte, Psychiatrische Universitätsklinik der Charité im St Hedwig Krankenhaus, Turmstrasse 21, D 10559, Berlin, Germany
    Neurosci Lett 375:151-6. 2005
    ....
  68. doi request reprint Pretreatment anterior cingulate activity predicts antidepressant treatment response in major depressive episodes
    Johannes Rentzsch
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Chariteplatz 1, 10117, Berlin, Germany
    Eur Arch Psychiatry Clin Neurosci 264:213-23. 2014
    ..This technique is advantageous due to its low individual and socioeconomic burden. The benefits of combining both, a clinically and a biologically based predictor, should be further evaluated using larger sample sizes...
  69. pmc Take home maintenance medication in opiate dependence
    Stefan Gutwinski
    Psychiatric University Hospital Charité, St Hedwig Hospital, Berlin, Germany
    Dtsch Arztebl Int 110:405-12. 2013
    ....
  70. pmc Does taste matter? How anticipation of cola brands influences gustatory processing in the brain
    Simone Kühn
    Clinic for Psychiatry and Psychotherapy, St Hedwig Krankenhaus, Charite University Medicine, Berlin, Germany
    PLoS ONE 8:e61569. 2013
    ..The present results reveal strong effects of brand labels on neural responses signalling reward...
  71. doi request reprint Manual dexterity correlating with right lobule VI volume in right-handed 14-year-olds
    Simone Kühn
    Department of Psychiatry and Psychotherapy, Charité University Medicine Campus Mitte, Berlin, Germany
    Neuroimage 59:1615-21. 2012
    ..Although neuronal cerebellar structures mediate dexterity, classical whole brain voxel-based morphometry (VBM) has not identified structural correlates of dexterity in the cerebellum...
  72. ncbi request reprint Association of EEG coherence and an exonic GABA(B)R1 gene polymorphism
    Georg Winterer
    Department of Psychiatry, University Hospital Benjamin Franklin, Free University of Berlin, Berlin, Germany
    Am J Med Genet B Neuropsychiatr Genet 117:51-6. 2003
    ..Since variations of EEG coherence have been described for several neuropsychiatric disorders, the present association should be tested in clinical samples using EEG coherence as an intermediate phenotype...
  73. ncbi request reprint Differential impact of heavy cannabis use on sensory gating in schizophrenic patients and otherwise healthy controls
    Johannes Rentzsch
    Department of Psychiatry, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Exp Neurol 205:241-9. 2007
    ..Our data provide some evidence that chronic cannabis abuse may affect sensory cortical circuits even after prolonged abstinence and they point to a possible differential effect in schizophrenic and otherwise healthy users...
  74. doi request reprint Gray matter correlates of posttraumatic stress disorder: a quantitative meta-analysis
    Simone Kühn
    Max Planck Institute for Human Development, Center for Lifespan Psychology, Berlin, Germany
    Biol Psychiatry 73:70-4. 2013
    ..Cerebral gray matter reductions have been suggested to be a crucial pathobiological marker of PTSD. However, a quantitative meta-analysis of whole-brain voxel-based morphometry studies is lacking...
  75. ncbi request reprint Nerve growth factor serum concentrations in healthy human volunteers: physiological variance and stability
    Undine E Lang
    Department of Psychiatry, Free University of Berlin, Eschenallee 3, 14050 Berlin, Germany
    Neurosci Lett 344:13-6. 2003
    ..This stability of our repetitive measurements over 4 weeks suggests that this neurotrophin may be an intraindividually solid marker at least in human serum...