Jurgen Popp

Summary

Affiliation: Friedrich Schiller University
Country: Germany

Publications

  1. doi request reprint Molecular self-healing mechanisms between C60-fullerene and anthracene unveiled by Raman and two-dimensional correlation spectroscopy
    R Geitner
    Institute for Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743, Jena, Germany
    Phys Chem Chem Phys 18:17973-82. 2016
  2. doi request reprint Characterization of carotenoids in soil bacteria and investigation of their photodegradation by UVA radiation via resonance Raman spectroscopy
    Vinay Kumar B N
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University of Jena, Helmholtzweg 4, D 07743 Jena, Germany
    Analyst 140:4584-93. 2015
  3. doi request reprint Multimodal Imaging Spectroscopy of Tissue
    Nadine Vogler
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, 07743 Jena, Germany email
    Annu Rev Anal Chem (Palo Alto Calif) 8:359-87. 2015
  4. pmc A study of Docetaxel-induced effects in MCF-7 cells by means of Raman microspectroscopy
    Katharina Hartmann
    Institute of Physical Chemistry and Abbe Center of Photonics, University of Jena, Helmholtzweg 4, 07743, Jena, Germany
    Anal Bioanal Chem 403:745-53. 2012
  5. pmc Raman spectroscopic detection of anthrax endospores in powder samples
    S Stöckel
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Jena, Germany
    Angew Chem Int Ed Engl 51:5339-42. 2012
  6. doi request reprint A new calibration concept for a reproducible quantitative detection based on SERS measurements in a microfluidic device demonstrated on the model analyte adenine
    Evelyn Kämmer
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University, Helmholtzweg 4, 07743 Jena, Germany
    Phys Chem Chem Phys 16:9056-63. 2014
  7. pmc Chemotaxonomic identification of single bacteria by micro-Raman spectroscopy: application to clean-room-relevant biological contaminations
    Petra Rosch
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Helmholtzweg 4, D 07743 Jena, Germany
    Appl Environ Microbiol 71:1626-37. 2005
  8. doi request reprint Hyperspectral unmixing of Raman micro-images for assessment of morphological and chemical parameters in non-dried brain tumor specimens
    Norbert Bergner
    Institute of Photonic Technology, Albert Einstein Straße 9, 07745, Jena, Germany
    Anal Bioanal Chem 405:8719-28. 2013
  9. ncbi request reprint On the way to nanometer-sized information of the bacterial surface by tip-enhanced Raman spectroscopy
    Ute Neugebauer
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, 07743 Jena, Germany
    Chemphyschem 7:1428-30. 2006
  10. ncbi request reprint The excited-state chemistry of protochlorophyllide a: a time-resolved fluorescence study
    Benjamin Dietzek
    Institut fur Physikalische Chemie, Bayerische Julius Maximilians Universität Würzburg, Am Hubland, 97074 Wurzburg, Germany
    Chemphyschem 7:1727-33. 2006

Detail Information

Publications121 found, 100 shown here

  1. doi request reprint Molecular self-healing mechanisms between C60-fullerene and anthracene unveiled by Raman and two-dimensional correlation spectroscopy
    R Geitner
    Institute for Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743, Jena, Germany
    Phys Chem Chem Phys 18:17973-82. 2016
    ....
  2. doi request reprint Characterization of carotenoids in soil bacteria and investigation of their photodegradation by UVA radiation via resonance Raman spectroscopy
    Vinay Kumar B N
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University of Jena, Helmholtzweg 4, D 07743 Jena, Germany
    Analyst 140:4584-93. 2015
    ..We also shed light on the influence of the structure of the carotenoid on its photodegradation which can be exploited for use in the characterization of carotenoids via resonance Raman spectroscopy. ..
  3. doi request reprint Multimodal Imaging Spectroscopy of Tissue
    Nadine Vogler
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, 07743 Jena, Germany email
    Annu Rev Anal Chem (Palo Alto Calif) 8:359-87. 2015
    ..We also discuss the advantages and potential limitations of the imaging methods and outline opportunities for future developments. ..
  4. pmc A study of Docetaxel-induced effects in MCF-7 cells by means of Raman microspectroscopy
    Katharina Hartmann
    Institute of Physical Chemistry and Abbe Center of Photonics, University of Jena, Helmholtzweg 4, 07743, Jena, Germany
    Anal Bioanal Chem 403:745-53. 2012
    ..Thereby we were able to differentiate treated from untreated MCF-7 cells and to quantify the cell-drug response by utilizing linear discriminant analysis models...
  5. pmc Raman spectroscopic detection of anthrax endospores in powder samples
    S Stöckel
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Jena, Germany
    Angew Chem Int Ed Engl 51:5339-42. 2012
  6. doi request reprint A new calibration concept for a reproducible quantitative detection based on SERS measurements in a microfluidic device demonstrated on the model analyte adenine
    Evelyn Kämmer
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University, Helmholtzweg 4, 07743 Jena, Germany
    Phys Chem Chem Phys 16:9056-63. 2014
    ..In doing so, a vast improvement in the quantification using SERS, especially in view of the comparability, reproducibility and repeatability, is demonstrated. ..
  7. pmc Chemotaxonomic identification of single bacteria by micro-Raman spectroscopy: application to clean-room-relevant biological contaminations
    Petra Rosch
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Helmholtzweg 4, D 07743 Jena, Germany
    Appl Environ Microbiol 71:1626-37. 2005
    ....
  8. doi request reprint Hyperspectral unmixing of Raman micro-images for assessment of morphological and chemical parameters in non-dried brain tumor specimens
    Norbert Bergner
    Institute of Photonic Technology, Albert Einstein Straße 9, 07745, Jena, Germany
    Anal Bioanal Chem 405:8719-28. 2013
    ..The role of non-linear Raman modalities to speed-up image acquisition is discussed. ..
  9. ncbi request reprint On the way to nanometer-sized information of the bacterial surface by tip-enhanced Raman spectroscopy
    Ute Neugebauer
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, 07743 Jena, Germany
    Chemphyschem 7:1428-30. 2006
  10. ncbi request reprint The excited-state chemistry of protochlorophyllide a: a time-resolved fluorescence study
    Benjamin Dietzek
    Institut fur Physikalische Chemie, Bayerische Julius Maximilians Universität Würzburg, Am Hubland, 97074 Wurzburg, Germany
    Chemphyschem 7:1727-33. 2006
    ....
  11. doi request reprint Widely tuneable fiber optical parametric amplifier for coherent anti-Stokes Raman scattering microscopy
    Mario Chemnitz
    Institute for Applied Physics, Abbe Center of Photonics, Friedrich Schiller Universtity Jena, Jena, Germany
    Opt Express 20:26583-95. 2012
    ..CARS spectroscopy and microscopy is demonstrated, probing different molecular vibrational modes within the accessible region between 1200cm(-1) and 3800cm(-1)...
  12. doi request reprint Expanding multimodal microscopy by high spectral resolution coherent anti-Stokes Raman scattering imaging for clinical disease diagnostics
    Tobias Meyer
    Institute of Photonic Technology Jena, Jena, Germany
    Anal Chem 85:6703-15. 2013
    ..Transfer of this highly precise but compact and simple to use imaging approach into clinical settings is expected in the near future. ..
  13. doi request reprint Light-induced dynamics in conjugated bis(terpyridine) ligands--a case study toward photoactive coordination polymers
    Ronald Siebert
    Institute for Physical Chemistry IPC, Friedrich Schiller University of Jena, Helmholtzweg 4, 07743 Jena, Germany
    Macromol Rapid Commun 33:481-97. 2012
    ....
  14. doi request reprint Isolation and enrichment of pathogens with a surface-modified aluminium chip for Raman spectroscopic applications
    Susanne Pahlow
    Spectroscopy and Imaging, Institute of Photonic Technology, Albert Einstein Str 9, 07745 Jena Germany, Fax 49 0 3641 206 399 Institute of Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena Germany
    Chemphyschem 14:3600-5. 2013
    ..Subsequent identification is done by recording Raman spectra of the bacteria. Further, it is shown that classification with chemometric methods is possible. ..
  15. doi request reprint Extremophile microbiomes in acidic and hypersaline river sediments of Western Australia
    Shipeng Lu
    Chair of Aquatic Geomicrobiology, Friedrich Schiller University Jena, Jena, Germany
    Environ Microbiol Rep 8:58-67. 2016
    ..The detection of Aplasma group as potential Fe(II) oxidizers and the inhibited Fe(III)-reducing capacity of Acidiphilium contributes to our understanding of the microbial ecology of acidic hypersaline environments. ..
  16. doi request reprint Single particle analysis of herpes simplex virus: comparing the dimensions of one and the same virions via atomic force and scanning electron microscopy
    Evelyn Kämmer
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743, Jena, Germany
    Anal Bioanal Chem 408:4035-41. 2016
    ..Graphical abstract The herpes simplex virus is investigated with scanning electron and atomic force microscopy in view of varying dimensions. ..
  17. doi request reprint Multimodal nonlinear microscopy of head and neck carcinoma - toward surgery assisting frozen section analysis
    Sandro Heuke
    Leibniz Institute of Photonic Technology, Jena, Germany
    Head Neck 38:1545-52. 2016
    ..Treatment of early cancer stages is deeply connected to a good prognosis, a moderate reduction of the quality of life, and comparably low treatment costs...
  18. doi request reprint Models for the active site in [FeFe] hydrogenase with iron-bound ligands derived from bis-, tris-, and tetrakis(mercaptomethyl)silanes
    Ulf Peter Apfel
    Institut für Anorganische und Analytische Chemie, Friedrich Schiller Universität Jena, August Bebel Strasse 2, D 07743 Jena, Germany
    Inorg Chem 49:10117-32. 2010
    ..This dinuclear complex, however, is slowly transformed into the tetranuclear species [Fe(4){μ-MeSi(CH(2)S)(3)}(2)(CO)(8)]...
  19. doi request reprint A manual and an automatic TERS based virus discrimination
    Konstanze Olschewski
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University, Helmholtzweg 4, 07743 Jena, Germany
    Nanoscale 7:4545-52. 2015
    ....
  20. doi request reprint Characterization of atherosclerotic plaque depositions by Raman and FTIR imaging
    Annika Lattermann
    University Hospital Friedrich Schiller University of Jena, Clinic for Internal Medicine I, Jena, Germany
    J Biophotonics 6:110-21. 2013
    ..These results correlate well with histopathology. The described method is a promising tool for easy and fast molecular imaging of atherosclerosis...
  21. doi request reprint Analysis of single blood cells for CSF diagnostics via a combination of fluorescence staining and micro-Raman spectroscopy
    Michaela Harz
    Institute of Physical Chemistry, Friedrich Schiller Universitat Jena, Helmholtzweg 4, D 07743 Jena, Germany
    Analyst 133:1416-23. 2008
    ..This capability with the possibility of accurate and rapid blood cell identification in cerebrospinal fluid is extremely promising for implementation in clinical diagnostics...
  22. doi request reprint Ultrafast plasmon dynamics and evanescent field distribution of reproducible surface-enhanced Raman-scattering substrates
    Dana Cialla
    Institute of Physical Chemistry, Friedrich Schiller University Jena Jenaer Biochip Initiative, Helmholtzweg 4, 07743, Jena, Germany
    Anal Bioanal Chem 394:1811-8. 2009
    ....
  23. doi request reprint A concept to tailor electron delocalization: applying QTAIM analysis to phenyl-terpyridine compounds
    Martin Presselt
    Institute of Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07743, Jena, Germany
    J Phys Chem A 114:13163-74. 2010
    ..Furthermore, the ellipticity in the BCP of the py-ph bond is related to the corresponding geometrical properties (e.g., bond length and dihedral angle) and to the DFT-calculated HOMO and LUMO energies...
  24. doi request reprint Fiber probe for nonlinear imaging applications
    Aleksandar Lukić
    Friedrich Schiller University of Jena, Institute of Physical Chemistry and Abbe Center of Photonics, Helmholtzweg 4, 07743, Jena, Germany
    J Biophotonics 9:138-43. 2016
    ..Therefore the scanning procedure can be shifted from the distal to the proximal end of the fiber probe and no moving parts or driving current are required to realize in-vivo CARS endoscopy...
  25. doi request reprint CORM-EDE1: A Highly Water-Soluble and Nontoxic Manganese-Based photoCORM with a Biogenic Ligand Sphere
    Ralf Mede
    Institute of Inorganic and Analytical Chemistry, Friedrich Schiller University Jena, Humboldtstraße, 8, D 07743 Jena, Germany
    Inorg Chem 55:104-13. 2016
    ..After CO liberation, the formation of MnHPO4 in aqueous buffer solution can be verified. ..
  26. doi request reprint Hepatic Vitamin A Content Investigation Using Coherent Anti-Stokes Raman Scattering Microscopy
    Fisseha Bekele Legesse
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743, Jena, Germany
    Chemphyschem 17:4043-4051. 2016
    ..The results obtained envisage the good prospect of the technique for in vivo studies assessing vitamin A distribution heterogeneity and how it is affected by the progression of hepatic diseases...
  27. doi request reprint Synthesis and solution stability of water-soluble κ2N,κO-bis(3,5-dimethylpyrazolyl)ethanol manganese(i) tricarbonyl bromide (CORM-ONN1)
    Ralf Mede
    Institute of Inorganic and Analytical Chemistry, Friedrich Schiller University FSU, Humboldstraße 8, D 07743 Jena, Germany
    Dalton Trans . 2017
    ....
  28. doi request reprint Quantitative SERS studies by combining LOC-SERS with the standard addition method
    Evelyn Kämmer
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743, Jena, Germany
    Anal Bioanal Chem 407:8925-9. 2015
    ..Due to the developed approach, a direct detection out of the sample and in the presence of an interfering substance was possible. ..
  29. doi request reprint Self-healing mechanism of metallopolymers investigated by QM/MM simulations and Raman spectroscopy
    Stephan Kupfer
    Institute for Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07743, Jena, Germany
    Phys Chem Chem Phys 16:12422-32. 2014
    ..However, such calculations on model clusters revealed relatively strong binding of the clusters, which renders reversible cluster breaking and reformation upon temperature cycling in the range up to 100 °C unlikely...
  30. doi request reprint Synthesis and characterization of regioselective substituted tetrapyridophenazine ligands and their Ru(II) complexes
    Michael Karnahl
    Institute of Inorganic and Analytical Chemistry, Friedrich Schiller University Jena, August Bebel Strasse 2, 07743, Jena, Germany
    Dalton Trans 39:2359-70. 2010
    ..A clear influence caused by the electronic effects of the different type and position of the substituents of tpphz on the photophysical behavior was observed...
  31. doi request reprint Resonance-Raman spectro-electrochemistry of intermediates in molecular artificial photosynthesis of bimetallic complexes
    Linda Zedler
    Institute of Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany
    Chem Commun (Camb) 50:5227-9. 2014
    ....
  32. doi request reprint Online-calibration for reliable and robust lab-on-a-chip surface enhanced Raman spectroscopy measurement in a liquid/liquid segmented flow
    Anne März
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Jena, Germany
    Anal Chem 83:8337-40. 2011
    ..In this contribution, we present a new approach to achieve reliable and robust measurements based on segmented flow LOC-SERS via online-wavenumber calibration...
  33. doi request reprint Alignment-free, all-spliced fiber laser source for CARS microscopy based on four-wave-mixing
    Martin Baumgartl
    Institute of Applied Physics, Abbe Center of Photonics, Friedrich Schiller Universitat Jena, Albert Einstein Str 15, 07745 Jena, Germany
    Opt Express 20:21010-8. 2012
    ..Due to its simplicity, compactness, maintenance-free operation, and ease-of-use the presented low-cost laser is an ideal source for bio-medical applications outside laser laboratories and in particular inside clinics...
  34. doi request reprint Quartz microfluidic chip for tumour cell identification by Raman spectroscopy in combination with optical traps
    Sebastian Dochow
    Institute of Photonic Technology, Jena, Germany
    Anal Bioanal Chem 405:2743-6. 2013
    ..Mean sensitivity and specificity determined by iterated 10-fold cross validation were 96 and 99 %, respectively, for the distinction of leucocytes extracted from blood, breast cancer cells BT-20 and MCF-7, and leukaemia cells OCI-AML3...
  35. doi request reprint STXM and NanoSIMS investigations on EPS fractions before and after adsorption to goethite
    Xinran Liu
    Institut fur Geowissenschaften, Friedrich Schiller Universitat Jena, Germany
    Environ Sci Technol 47:3158-66. 2013
    ..e., of two materials which will strongly differ in their reactive sites. This will finally affect further adsorption, the particle mobility and eventually also colloidal stability...
  36. doi request reprint Morphology-sensitive Raman modes of the malaria pigment hemozoin
    Torsten Frosch
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Helmholtzweg 4, D 07743 Jena, Germany
    Analyst 134:1126-32. 2009
    ..830 nm. In conclusion, resonance Raman micro-spectroscopy with lambda(exc.) = 647 nm was shown to have great potential as an analytical tool to probe the morphology of hematin samples...
  37. doi request reprint UV cross-linking of unmodified DNA on glass surfaces
    Thomas Schüler
    Jenaer Biochip Initiative, Institute of Physical Chemistry, Friedrich Schiller University, Helmholtzweg 4, 07743 Jena, Germany
    Anal Bioanal Chem 395:1097-105. 2009
    ..However, higher binding rates can be achieved when using amino-modified oligonucleotides on an epoxy surface. The limit of detection for the used settings was 5 pM...
  38. doi request reprint Analysis of the cytochrome distribution via linear and nonlinear Raman spectroscopy
    Angela Walter
    Institute of Physical Chemistry, Friedrich Schiller University, Helmholtzweg 4, 07743 Jena, Germany
    Analyst 135:908-17. 2010
    ..commune or other basidiomycetous fungi, by means of resonance Raman microspectroscopy and CARS microscopy. These Raman methods bear the potential of label-free in vivo mitochondria localization and investigation...
  39. doi request reprint Protein-induced excited-state dynamics of protochlorophyllide
    Robert Hanf
    Institute for Physical Chemistry and Abbe Centre of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, D 07743 Jena, Germany
    J Phys Chem A 115:7873-81. 2011
    ..The possible relevance of this result for the catalytic reaction in the enzyme POR is discussed...
  40. pmc Towards multiple readout application of plasmonic arrays
    Dana Cialla
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany
    Beilstein J Nanotechnol 2:501-8. 2011
    ..The results shown open the way to more flexible use of plasmonic arrays in bioanalytics...
  41. doi request reprint Ruthenium polypyridine complexes of tris-(2-pyridyl)-1,3,5-triazine-unusual building blocks for the synthesis of photochemical molecular devices
    Matthias Schwalbe
    Institute for Inorganic and Analytical Chemistry, Friedrich Schiller University Jena, August Bebel Str, 2, 07743 Jena, Germany
    Dalton Trans . 2009
    ..Preliminary investigations show that the dinuclear ruthenium-palladium and -platinum complexes are not active catalysts in the light-driven hydrogen production...
  42. doi request reprint Raman spectroscopic imaging for the real-time detection of chemical changes associated with docetaxel exposure
    Katharina Bräutigam
    Institute of Physical Chemistry and Abbe Center of Photonics, University of Jena, Helmholtzweg 4, 07743 Jena, Germany
    Chemphyschem 14:550-3. 2013
    ..The work presented paves the way for establishing Raman spectroscopy as a monitoring tool of the effectiveness of a chemotherapy treatment and can therefore be seen as a step towards personalized therapy...
  43. doi request reprint Schwertmannite formation at cell junctions by a new filament-forming Fe(II)-oxidizing isolate affiliated with the novel genus Acidithrix
    Jiro F Mori
    1 Aquatic Geomicrobiology, Friedrich Schiller University Jena, Jena, Germany
    Microbiology 162:62-71. 2016
    ..Thus, strain C25 appeared to have ecological relevance for both the formation and transformation of the pelagic iron-rich aggregates at oxic/anoxic transition zones in the acidic lignite mine lake...
  44. doi request reprint Systematic evaluation of the biological variance within the Raman based colorectal tissue diagnostics
    Nadine Vogler
    Leibniz Institute of Photonic Technology, 07745, Jena, Germany
    J Biophotonics 9:533-41. 2016
    ..Furthermore, the transfer of a model from tissue to biopsy specimen is demonstrated. ..
  45. doi request reprint A comparative Raman and CARS imaging study of colon tissue
    Christoph Krafft
    Institute of Photonic Technology, Germany, Albert Einstein Str 9, 07745 Jena, Germany
    J Biophotonics 2:303-12. 2009
    ..This first comparison establishes the foundation for further development of the CARS technology to assess tissue...
  46. doi request reprint Trapped in imidazole: how to accumulate multiple photoelectrons on a black-absorbing ruthenium complex
    Linda Zedler
    Institute of Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena Germany, Fax 49 3641 948302
    Chemistry 20:3793-9. 2014
    ..Thereby, an efficient two-electron pathway to the 4H-imidazole electron-accepting ligand is identified. ..
  47. doi request reprint Novel workflow for combining Raman spectroscopy and MALDI-MSI for tissue based studies
    Thomas Bocklitz
    Institute of Physical Chemistry and Abbe Center of Photonics, University of Jena, Helmholtzweg 4, 07743, Jena, Germany
    Anal Bioanal Chem 407:7865-73. 2015
    ..Further investigations with the help of MALDI spectra yield a better characterization of variable epithelial differentiation and a better understanding of ongoing dysplastic alterations. ..
  48. doi request reprint Rapid Identification of Pseudomonas spp. via Raman Spectroscopy Using Pyoverdine as Capture Probe
    Susanne Pahlow
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany
    Anal Chem 88:1570-7. 2016
    ..aeruginosa and P. fluorescens from tap water samples, which are both opportunistic pathogens and can pose a threat for immunocompromised patients. ..
  49. doi request reprint Culture independent Raman spectroscopic identification of urinary tract infection pathogens: a proof of principle study
    Sandra Kloss
    Institute of Physical Chemistry and Abbe Center of Photonics, University of Jena, Helmholtzweg 4, D 07743 Jena, Germany
    Anal Chem 85:9610-6. 2013
    ..These results demonstrate that Raman microspectroscopy in combination with support vector machines allow an identification of important UTI bacteria within two hours without the need of a culture step. ..
  50. doi request reprint Towards a quantitative SERS approach--online monitoring of analytes in a microfluidic system with isotope-edited internal standards
    Anne März
    Institute of Physical Chemistry, Friedrich Schiller University Jena, Jena, Germany
    J Biophotonics 2:232-42. 2009
    ..To the best of our knowledge these are the first measurements combining the above mentioned concepts in order to correct for differences in the enhancement behaviour of the respective colloid...
  51. doi request reprint The switch that wouldn't switch--unexpected luminescence from a ruthenium(II)-dppz-complex in water
    Matthias Schwalbe
    Institute of Inorganic and Analytical Chemistry, August Bebel Str 2, 07743 Jena, Germany
    Dalton Trans 39:2768-71. 2010
    ..The complex [(dmcb)(2)Ru(dppz)](PF(6))(2) shows unexpected luminescence in water implying fundamentally different excited state relaxation pathways than are typically observed for complexes of this kind...
  52. doi request reprint Tumour cell identification by means of Raman spectroscopy in combination with optical traps and microfluidic environments
    Sebastian Dochow
    Institute of Photonic Technology, Jena, Germany
    Lab Chip 11:1484-90. 2011
    ..Implementation into microfluidic environments enables a high degree of automation that is required to improve the throughput of the approach for Raman activated cell sorting...
  53. doi request reprint From bulk to single-cell classification of the filamentous growing Streptomyces bacteria by means of Raman spectroscopy
    Angela Walter
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat, Helmholtzweg 4, 07743 Jena, Germany
    Appl Spectrosc 65:1116-25. 2011
    ..The classification utilizing a tree-like classifier is also applied to the Streptomyces single-cell spectra, resulting in classification accuracies between 80 and 93% for the investigated Streptomyces species...
  54. doi request reprint Towards automated segmentation of cells and cell nuclei in nonlinear optical microscopy
    Anna Medyukhina
    Institute of Photonic Technology IPHT Jena eV, Jena, Germany
    J Biophotonics 5:878-88. 2012
    ..The results are important for the development of NLO microscopy into a clinically relevant diagnostic tool...
  55. doi request reprint Toward improving fine needle aspiration cytology by applying Raman microspectroscopy
    Melanie Becker-Putsche
    University of Jena, Institute of Physical Chemistry and Abbe Center of Photonics, Helmholtzweg 4, 07743 Jena, Germany
    J Biomed Opt 18:047001. 2013
    ..This work shows the applicability of Raman spectroscopy and statistical data handling in analyzing cancer-relevant biochemical information for advanced medical diagnosis on the single-cell level...
  56. doi request reprint Raman spectroscopy-an innovative and versatile tool to follow the respirational activity and carbonate biomineralization of important cave bacteria
    Robert Keiner
    Institute of Photonic Technology, Institute for Physical Chemistry, Institute of Ecology, and Abbe School of Photonics, Friedrich Schiller University, Jena, Germany
    Anal Chem 85:8708-14. 2013
    ....
  57. doi request reprint Microarray-based detection of dye-labeled DNA by SERRS using particles formed by enzymatic silver deposition
    Katharina Konstanze Hering
    Jenaer Biochip Initiative, Institute of Physical Chemistry, Friedrich Schiller Universitat Jena, Helmholtzweg 4, 07745 Jena, Germany
    Chemphyschem 9:867-72. 2008
    ..The nanoparticles are characterized and their ability for use as SERS- and SERRS-active substrate is estimated. Three different Raman-active dyes are investigated for their potential for involvement in sequence specific DNA analysis...
  58. doi request reprint SERS as tool for the analysis of DNA-chips in a microfluidic platform
    Katharina K Strelau
    Jenaer Biochip Initiative, Institute of Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07745 Jena, Germany
    Anal Bioanal Chem 396:1381-4. 2010
    ..With this setup, we are able to distinguish between different complementary and non-complementary target sequences in one sample solution...
  59. doi request reprint Raman spectroscopic detection of physiology changes in plasmid-bearing Escherichia coli with and without antibiotic treatment
    Angela Walter
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat, Jena, Germany
    Anal Bioanal Chem 400:2763-73. 2011
    ..Independent cultural replicates of either ampicillin-challenged or non-challenged cultures are successfully identified with identification rates of over 90%...
  60. pmc Comparing Raman and fluorescence lifetime spectroscopy from human atherosclerotic lesions using a bimodal probe
    Sebastian Dochow
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743, Jena, Germany
    J Biophotonics 9:958-66. 2016
    ..Both modalities demonstrate unique strengths and weaknesses and these will be discussed in comparison to histologic analyses from the two coronary arteries imaged. ..
  61. ncbi request reprint Hepatic cirrhosis and recovery as reflected by Raman spectroscopy: information revealed by statistical analysis might lead to a prognostic biomarker
    Kerstin Galler
    Leibniz Institute of Photonic Technology, Albert Einstein Str 9, 07745, Jena, Germany
    Anal Bioanal Chem 408:8053-8063. 2016
    ....
  62. doi request reprint Raman spectroscopic identification of Mycobacterium tuberculosis
    Stephan Stöckel
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University of Jena, Helmholtzweg 4, 07743, Jena, Germany
    J Biophotonics . 2016
    ....
  63. doi request reprint Raman spectroscopic differentiation of planktonic bacteria and biofilms
    Dragana Kusić
    Institut für Physikalische Chemie and Abbe Center of Photonics, Friedrich Schiller Universitat Jena, Helmholtzweg 4, 07743, Jena, Germany
    Anal Bioanal Chem 407:6803-13. 2015
    ..Our results provide valuable data for the development of fast and reliable analytic methods based on Raman microspectroscopy, which can be applied to the analysis of tap water-adapted microorganisms without any cultivation step...
  64. doi request reprint Pinus sylvestris switches respiration substrates under shading but not during drought
    Sarah Fischer
    Max Planck Institute for Biogeochemistry, Hans Knöll Str 10, 07745, Jena, Germany
    New Phytol 207:542-50. 2015
    ..Thus, respiratory substrate shift cannot provide an efficient means to counterbalance C limitation under natural drought. ..
  65. doi request reprint Isolation and identification of bacteria by means of Raman spectroscopy
    Susanne Pahlow
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743, Germany InfectoGnostics Research Campus Jena, Center for Applied Research, Philosophenweg 7, 07743 Jena, Germany
    Adv Drug Deliv Rev 89:105-20. 2015
    ..Here, an overview of the limitations and possibilities of these methods is provided. Furthermore, the utilization of Raman spectroscopy for diagnostic purposes, food safety and environmental issues is discussed under a critical view. ..
  66. doi request reprint How to pre-process Raman spectra for reliable and stable models?
    Thomas Bocklitz
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University, Jena, Germany
    Anal Chim Acta 704:47-56. 2011
    ..The suggested GA procedure results in models, which have a higher precision and are more stable against corrupting effects...
  67. doi request reprint Raman spectroscopic detection and identification of Burkholderia mallei and Burkholderia pseudomallei in feedstuff
    Stephan Stöckel
    Institute of Physical Chemistry and Abbe School of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743, Jena, Germany
    Anal Bioanal Chem 407:787-94. 2015
    ..9 and 98.7%. The sample analysis itself requires no biomass enrichment step prior to the analysis and can be performed under biosafety level 1 (BSL 1) conditions after inactivating the bacteria with formaldehyde...
  68. doi request reprint Single virus detection by means of atomic force microscopy in combination with advanced image analysis
    Thomas Bocklitz
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany InfectoGnostics Forschungscampus Jena e V, Zentrum für Angewandte Forschung, Philosophenweg 7, 07743 Jena, Germany Leibniz Institute of Photonic Technology, Albert Einstein Strasse 9, 07745 Jena, Germany Electronic address
    J Struct Biol 188:30-8. 2014
    ..Due to the application of advanced image analysis the morphology could be quantified and used for further analysis. Here, an automatic recognition by means of a classification model could be achieved in a reliable and objective manner. ..
  69. doi request reprint Identification of meat-associated pathogens via Raman microspectroscopy
    Susann Meisel
    Institute of Physical Chemistry and Abbe Center of Photonics, University of Jena, Helmholtzweg 4, D 07743 Jena, Germany
    Food Microbiol 38:36-43. 2014
    ..The test samples were correctly assigned to their genus and for the most part down to the species-level i.e. a differentiation from closely-related non-pathogenic members was achieved. ..
  70. ncbi request reprint Excited-state annihilation in a homodinuclear ruthenium complex
    Christian Kuhnt
    Institute for Physical Chemistry, Friedrich Schiller University Jena, Jena Center of Soft Matter and Abbe Center of Photonics, Helmhotzweg 4, 07743 Jena, Germany
    Chem Commun (Camb) 47:3820-1. 2011
    ..The observation of pump-intensity dependent triplet-triplet annihilation highlights the importance of considering various loss mechanisms in the design of artificial photosynthetic assemblies...
  71. doi request reprint Detection of thiopurine methyltransferase activity in lysed red blood cells by means of lab-on-a-chip surface enhanced Raman spectroscopy (LOC-SERS)
    Anne März
    Institute of Physical Chemisty, Friedrich Schiller University, Jena, Germany
    Anal Bioanal Chem 400:2755-61. 2011
    ..Being able to determine the TPMT activity before starting a treatment using 6-mercaptopurine, an optimized dosage can be applied to each patient and serious toxicity appearing within thiopurine treatment will be prevented...
  72. doi request reprint Metal-mediated reaction modeled on nature: the activation of isothiocyanates initiated by zinc thiolate complexes
    Wilhelm A Eger
    Institut fur Organische Chemie und Makromolekulare Chemie, Friedrich Schiller Universitat Jena, Humboldtstrasse 10, 07743 Jena, Germany
    Inorg Chem 50:3223-33. 2011
    ..In addition, the presented synthetic pathways can offer a completely new access to a variety of dithiocarbamates...
  73. doi request reprint Protonation effects on the resonance Raman properties of a novel (terpyridine)Ru(4H-imidazole) complex: an experimental and theoretical case study
    Stephan Kupfer
    Institute for Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07743, Jena, Germany
    Phys Chem Chem Phys 13:15580-8. 2011
    ..Finally, the examination of the molecular orbitals and of the RR spectra for the MLCT state shows that protonation favors a charge transfer excitation to the 4H-imidazole ligand...
  74. ncbi request reprint Catalytic efficiency of a photoenzyme-an adaptation to natural light conditions
    Robert Hanf
    Friedrich Schiller Universitat Jena, Institut fur Physikalische Chemie, Helmholtzweg 4, 07743 Jena Germany, Fax 49 3641 948302
    Chemphyschem 13:2013-5. 2012
    ..It becomes evident that "red" photons are more efficiently utilized in enzyme catalysis than "blue" photons. This shows an adaptation of the enzyme activity to the natural light conditions...
  75. doi request reprint Multimodal nonlinear microscopic investigations on head and neck squamous cell carcinoma: toward intraoperative imaging
    Tobias Meyer
    Institute of Photonic Technology, Jena, Germany
    Head Neck 35:E280-7. 2013
    ..A promising noninvasive alternative is nonlinear optical imaging, which is capable of in vivo tissue visualization for tumor typing and grading...
  76. doi request reprint Sample size planning for classification models
    Claudia Beleites
    Department of Spectroscopy and Imaging, Institute of Photonic Technology, Jena, Germany
    Anal Chim Acta 760:25-33. 2013
    ....
  77. doi request reprint Towards a fast, high specific and reliable discrimination of bacteria on strain level by means of SERS in a microfluidic device
    Angela Walter
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Jena, Germany
    Lab Chip 11:1013-21. 2011
    ..Within this contribution the potential of our approach of bacterial identification for future application is discussed, focusing on the time-benefit and the combination with other microfluidic applications...
  78. doi request reprint Toward a spectroscopic hemogram: Raman spectroscopic differentiation of the two most abundant leukocytes from peripheral blood
    Anuradha Ramoji
    Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany
    Anal Chem 84:5335-42. 2012
    ..This marks a promising step toward automated Raman spectroscopic blood analysis which holds the potential not only to assign the numbers of the cells but also to yield important biochemical information...
  79. doi request reprint Ru dye functionalized Au-SiO2@TiO2 and Au/Pt-SiO2@TiO2 nanoassemblies for surface-plasmon-induced visible light photocatalysis
    Frank Theil
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, Jena, Germany Leibniz Institute of Photonic Technology IPHT Jena e V, Albert Einstein Str 9, Jena, Germany
    J Colloid Interface Sci 421:114-21. 2014
    ..The photocatalytic activity of the nanostructures shows up to 52% higher first order rate constants compared to the corresponding nanostructures without further dye functionalization. ..
  80. ncbi request reprint On-line monitoring and identification of bioaerosols
    Petra Rosch
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Helmholtzweg 4, D 07743 Jena, Germany
    Anal Chem 78:2163-70. 2006
    ..Since only the biotic particles are of interest, the analysis time can be minimized due to reduction of the data set. The biotic particles are then analyzed further with Raman spectroscopy and identified with a support vector machine...
  81. ncbi request reprint SERS: a versatile tool in chemical and biochemical diagnostics
    Katharina Hering
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Helmholtzweg 4, 07743, Jena, Germany
    Anal Bioanal Chem 390:113-24. 2008
    ..Here, rough coin metal surfaces enhance the Raman signal by a factor of 10(4)-10(15), depending on the applied method. In this review we discuss recent developments in SERS spectroscopy and their impact on different research fields...
  82. ncbi request reprint Quantitative online detection of low-concentrated drugs via a SERS microfluidic system
    Katrin R Ackermann
    Institute of Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany
    Chemphyschem 8:2665-70. 2007
    ....
  83. doi request reprint Probing innovative microfabricated substrates for their reproducible SERS activity
    Dana Cialla
    Friedrich Schiller University Jena, Department of Physical Chemistry, Jenaer Biochip Initiative JBCI, Helmholtzweg 4, 07743 Jena, Germany
    Chemphyschem 9:758-62. 2008
    ..To test the SERS activity of these nanostar and nanodiamond arrays, a monolayer of the dye crystal violet is used. Enhancement factors are estimated to be at least 130 for the nanodiamond and 310 for the nanostar arrays...
  84. doi request reprint A disposable and cost efficient microfluidic device for the rapid chip-based electrical detection of DNA
    Thomas Schüler
    Jenaer Biochip Initiative, Friedrich Schiller University, Institute of Physical Chemistry, Helmholtzweg 4, Jena, Germany
    Biosens Bioelectron 25:15-21. 2009
    ..These first steps of automation and integration will help to realize a laboratory-independent bioanalytical tool, for the use outside of specialized laboratories for fast analysis of different chemical and biological applications...
  85. doi request reprint Fluorescence dye as novel label molecule for quantitative SERS investigations of an antibiotic
    Anne März
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany
    Anal Bioanal Chem 402:2625-31. 2012
    ..With the new concept of binding the label molecule directly to the analyte molecule, the application of linkage compounds like antibodies or any other recognition molecules becomes dispensable...
  86. pmc Raman spectroscopy as a potential tool for detection of Brucella spp. in milk
    Susann Meisel
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Jena, Germany
    Appl Environ Microbiol 78:5575-83. 2012
    ..The measurements we performed at the single-cell level thus allow fast identification within a few hours without a demanding process for sample preparation...
  87. ncbi request reprint Surface-enhanced Raman spectroscopy (SERS): progress and trends
    Dana Cialla
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Jena, Germany
    Anal Bioanal Chem 403:27-54. 2012
    ..To benefit from synergies, SERS is combined with other methods, such as scanning probe microscopy and microfluidics, which illustrates the broad applications of this powerful technique...
  88. doi request reprint Non-invasive depth profile imaging of the stratum corneum using confocal Raman microscopy: first insights into the method
    Mukul Ashtikar
    Friedrich Schiller Universitat Jena, Institut fur Pharmazie, Lehrstuhl für Pharmazeutische Technologie, Lessingstraße 8, 07743 Jena, Germany Electronic address
    Eur J Pharm Sci 50:601-8. 2013
    ..We present Raman images of untreated skin and diffusion patterns for deuterated water and beta-carotene after Franz-cell diffusion experiment. ..
  89. doi request reprint In vivo characterization of atherosclerotic plaque depositions by Raman-probe spectroscopy and in vitro coherent anti-stokes Raman scattering microscopic imaging on a rabbit model
    Christian Matthäus
    Institute of Photonic Technology, Jena, Germany
    Anal Chem 84:7845-51. 2012
    ..In order to further characterize the plaque depositions visually, coherent anti-Stokes Raman scattering (CARS) microscopy images have been acquired and are compared with the Raman-probe results...
  90. doi request reprint Quantitative assessment of the degree of lipid unsaturation in intact Mortierella by Raman microspectroscopy
    Ute Münchberg
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743, Jena, Germany
    Anal Bioanal Chem 407:3303-11. 2015
    ..We find Raman microspectroscopy a suitable tool to determine the IV reliably, fast, and easily inside intact hyphae without extensive sample handling or treatment. The method can also be transferred to other microscopic samples. ..
  91. doi request reprint Characterizing cytochrome c states--TERS studies of whole mitochondria
    René Böhme
    Institute of Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany
    Chem Commun (Camb) 47:11453-5. 2011
    ..Protein structures (cytochrome c) were visualized by TERS measurements on whole mitochondria referring to specific spectral features describing the electronic state of the heme moiety...
  92. doi request reprint Self-healing polymer coatings based on crosslinked metallosupramolecular copolymers
    Stefan Bode
    Laboratory of Organic and Macromolecular Chemistry IOMC, Friedrich Schiller University Jena, Jena, Germany
    Adv Mater 25:1634-8. 2013
    ..Moreover, the influence of the comonomers on the thermal properties is studied in detail...
  93. ncbi request reprint Quality control of commercially available essential oils by means of Raman spectroscopy
    Katrin R Strehle
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Helmholtzweg 4, D 07743 Jena, Germany
    J Agric Food Chem 54:7020-6. 2006
    ..In addition, cross-sections of anise seeds were analyzed applying the Raman mapping technique to localize and investigate the distribution of the oil in situ...
  94. ncbi request reprint In situ localization and structural analysis of the malaria pigment hemozoin
    Torsten Frosch
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Helmholtzweg 4, D 07743 Jena, Germany
    J Phys Chem B 111:11047-56. 2007
    ....
  95. ncbi request reprint UV Raman spectroscopy--a technique for biological and mineralogical in situ planetary studies
    Nicolae Tarcea
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Helmholtzweg 4, D 07743 Jena, Germany
    Spectrochim Acta A Mol Biomol Spectrosc 68:1029-35. 2007
    ..Making use of the resonance effects, spectra of microorganisms were recorded with a high S/N ratio, allowing afterwards a very precise identification and classification (to the strain level) of the measured samples...
  96. doi request reprint Localizing and identifying living bacteria in an abiotic environment by a combination of Raman and fluorescence microscopy
    Mario Krause
    Institute for Physical Chemistry, University of Jena, Helmholtzweg 4, 07743 Jena, Germany
    Anal Chem 80:8568-75. 2008
    ..The living cells were identified by means of Raman spectroscopy in combination with a support vector machine. Furthermore, the localization of bacterial cells in a mix of abiotic particles is demonstrated...
  97. doi request reprint Direct analysis of clinical relevant single bacterial cells from cerebrospinal fluid during bacterial meningitis by means of micro-Raman spectroscopy
    Michaela Harz
    Institute of Physical Chemistry, Friedrich Schiller Universitat Jena, Helmholtzweg 4, Jena, Germany
    J Biophotonics 2:70-80. 2009
    ..meningitidis cells from patients with bacterial meningitis could be achieved...
  98. doi request reprint Raman spectroscopic determination of norbixin and tartrazine in sugar
    Ute Uhlemann
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller Universitat, Jena, Germany
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 29:1244-55. 2012
    ..A detection limit of 250 ng g⁻¹ for norbixin and 989 ng g⁻¹ for tartrazine in solid sugar samples could be reached by logistic regression...
  99. doi request reprint Dual emission from highly conjugated 2,2':6':2″-terpyridine complexes-a potential route to white emitters
    Ronald Siebert
    Institute for Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany
    Macromol Rapid Commun 31:883-8. 2010
    ..Thus, by structurally tuning the electronic coupling of the ππ* and the MLCT states a new synthetic route toward white emitters, which can subsequently be incorporated into polymers, is opened...
  100. ncbi request reprint Droplet formation via flow-through microdevices in Raman and surface enhanced Raman spectroscopy--concepts and applications
    Anne März
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany
    Lab Chip 11:3584-92. 2011
    ..Within this contribution, previous reported applications on droplet-based flow-through Raman and SERS approaches and the additional benefit with regard to the importance in the field of analytics are considered...