Hana Valenta

Summary

Affiliation: Federal Agricultural Research Centre
Country: Germany

Publications

  1. ncbi request reprint Study on the transmission of deoxynivalenol and de-epoxy-deoxynivalenol into eggs of laying hens using a high-performance liquid chromatography-ultraviolet method with clean-up by immunoaffinity columns
    Hana Valenta
    Institute of Animal Nutrition, Federal Agricultural Research Centre FAL, Braunschweig, Germany
    Mol Nutr Food Res 49:779-85. 2005
  2. doi request reprint Humic substances failed to prevent the systemic absorption of deoxynivalenol (DON) and its adverse effects on piglets
    Sven Dänicke
    Federal Research Institute for Animal Health, Bundesallee 50, 38116, Braunschweig, Germany
    Mycotoxin Res 28:253-60. 2012
  3. ncbi request reprint Carry-over of Fusarium toxins (deoxynivalenol and zearalenone) from naturally contaminated wheat to pigs
    Tanja Goyarts
    Institute of Animal Nutrition, Federal Agricultural Research Centre, Braunschweig, Germany
    Food Addit Contam 24:369-80. 2007
  4. doi request reprint Inactivation of deoxynivalenol-contaminated cereal grains with sodium metabisulfite: a review of procedures and toxicological aspects
    Sven Dänicke
    Federal Research Institute for Animal Health, Bundesallee 50, 38116, Braunschweig, Germany
    Mycotoxin Res 28:199-218. 2012
  5. doi request reprint Investigations on the kinetics of the concentration of deoxynivalenol (DON) and on spoilage by moulds and yeasts of wheat grain preserved with sodium metabisulfite (Na2S2O5, SBS) and propionic acid at various moisture contents
    Sven Dänicke
    Institute of Animal Nutrition, Friedrich Loeffler Institute FLI, Federal Research Institute for Animal Health, Braunschweig, Germany
    Arch Anim Nutr 64:190-203. 2010
  6. doi request reprint Effects of a Fusarium toxin-contaminated triticale, either untreated or treated with sodium metabisulphite (Na2S2O5, SBS), on weaned piglets with a special focus on liver function as determined by the 13C-methacetin breath test
    Sven Dänicke
    Institute of Animal Nutrition, Friedrich Loeffler lnstitute FLI, Federal Research Institute for Animal Health, Braunschweig, Germany
    Arch Anim Nutr 62:263-86. 2008
  7. ncbi request reprint Influence of a Fusarium culmorum inoculation of wheat on the progression of mycotoxin accumulation, ingredient concentrations and ruminal in sacco dry matter degradation of wheat residues
    Ute Brinkmeyer
    Institute of Animal Nutrition, Federal Agricultural Research Centre FAL Braunschweig, Germany
    Arch Anim Nutr 60:141-57. 2006
  8. doi request reprint Bioavailability of the Fusarium toxin deoxynivalenol (DON) from wheat straw and chaff in pigs
    Dirk Rohweder
    Institute of Animal Nutrition, Friedrich Loeffler Institute, Federal Research Institute for Animal Health, Braunschweig, Germany
    Arch Anim Nutr 67:37-47. 2013
  9. doi request reprint Residues of deoxynivalenol (DON) in pig tissue after feeding mash or pellet diets containing low concentrations
    Susanne Doll
    Institute of Animal Nutrition, Friedrich Loeffler Institute, Federal Research Institute for Animal Health, Braunschweig, Germany
    Mol Nutr Food Res 52:727-34. 2008
  10. doi request reprint Lipopolysaccharides (LPS) modulate the metabolism of deoxynivalenol (DON) in the pig
    Sven Dänicke
    Institute of Animal Nutrition, Friedrich Loeffler Institute FLI, Federal Research Institute for Animal Health, Bundesallee 50, 38116, Braunschweig, Germany
    Mycotoxin Res 30:161-70. 2014

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Study on the transmission of deoxynivalenol and de-epoxy-deoxynivalenol into eggs of laying hens using a high-performance liquid chromatography-ultraviolet method with clean-up by immunoaffinity columns
    Hana Valenta
    Institute of Animal Nutrition, Federal Agricultural Research Centre FAL, Braunschweig, Germany
    Mol Nutr Food Res 49:779-85. 2005
    ..Neither DON nor de-epoxy-DON or glucuronide conjugates of both substances could be detected in any of the samples. These results indicate that eggs do not contribute significantly to the dietary DON intake of humans...
  2. doi request reprint Humic substances failed to prevent the systemic absorption of deoxynivalenol (DON) and its adverse effects on piglets
    Sven Dänicke
    Federal Research Institute for Animal Health, Bundesallee 50, 38116, Braunschweig, Germany
    Mycotoxin Res 28:253-60. 2012
    ..1 and 20.2% for groups FUS and FUS-HS, respectively. In conclusion, the tested HS preparation cannot be recommended as a DON inactivating feed supplement for pigs...
  3. ncbi request reprint Carry-over of Fusarium toxins (deoxynivalenol and zearalenone) from naturally contaminated wheat to pigs
    Tanja Goyarts
    Institute of Animal Nutrition, Federal Agricultural Research Centre, Braunschweig, Germany
    Food Addit Contam 24:369-80. 2007
    ..However, the exposure risk to humans by consumption of edible tissues of animals exposed to Fusarium toxins is negligible compared to the direct consumption of grain-based food...
  4. doi request reprint Inactivation of deoxynivalenol-contaminated cereal grains with sodium metabisulfite: a review of procedures and toxicological aspects
    Sven Dänicke
    Federal Research Institute for Animal Health, Bundesallee 50, 38116, Braunschweig, Germany
    Mycotoxin Res 28:199-218. 2012
    ....
  5. doi request reprint Investigations on the kinetics of the concentration of deoxynivalenol (DON) and on spoilage by moulds and yeasts of wheat grain preserved with sodium metabisulfite (Na2S2O5, SBS) and propionic acid at various moisture contents
    Sven Dänicke
    Institute of Animal Nutrition, Friedrich Loeffler Institute FLI, Federal Research Institute for Animal Health, Braunschweig, Germany
    Arch Anim Nutr 64:190-203. 2010
    ..In conclusion, for the conditions examined, the wet preservation of DON-contaminated wheat with SBS seems to be promising as an on-farm detoxification measure...
  6. doi request reprint Effects of a Fusarium toxin-contaminated triticale, either untreated or treated with sodium metabisulphite (Na2S2O5, SBS), on weaned piglets with a special focus on liver function as determined by the 13C-methacetin breath test
    Sven Dänicke
    Institute of Animal Nutrition, Friedrich Loeffler lnstitute FLI, Federal Research Institute for Animal Health, Braunschweig, Germany
    Arch Anim Nutr 62:263-86. 2008
    ....
  7. ncbi request reprint Influence of a Fusarium culmorum inoculation of wheat on the progression of mycotoxin accumulation, ingredient concentrations and ruminal in sacco dry matter degradation of wheat residues
    Ute Brinkmeyer
    Institute of Animal Nutrition, Federal Agricultural Research Centre FAL Braunschweig, Germany
    Arch Anim Nutr 60:141-57. 2006
    ..culmorum of wheat involves an increased risk of mycotoxin contamination in straw. Also, a Fusarium infection may have an impact on chemical composition and may result in Fusarium growth-related modifications of host cell wall components...
  8. doi request reprint Bioavailability of the Fusarium toxin deoxynivalenol (DON) from wheat straw and chaff in pigs
    Dirk Rohweder
    Institute of Animal Nutrition, Friedrich Loeffler Institute, Federal Research Institute for Animal Health, Braunschweig, Germany
    Arch Anim Nutr 67:37-47. 2013
    ..9, 87.3 and 109.8% for straw, grain and chaff, respectively, without significant differences. Thus, the uptake of DON from straw may contribute comparably to the overall exposure of animals...
  9. doi request reprint Residues of deoxynivalenol (DON) in pig tissue after feeding mash or pellet diets containing low concentrations
    Susanne Doll
    Institute of Animal Nutrition, Friedrich Loeffler Institute, Federal Research Institute for Animal Health, Braunschweig, Germany
    Mol Nutr Food Res 52:727-34. 2008
    ..9 mg DON/kg, and those fed diets containing 137% of this concentration. The different feed forms did not affect residue concentrations in any of the investigated specimens...
  10. doi request reprint Lipopolysaccharides (LPS) modulate the metabolism of deoxynivalenol (DON) in the pig
    Sven Dänicke
    Institute of Animal Nutrition, Friedrich Loeffler Institute FLI, Federal Research Institute for Animal Health, Bundesallee 50, 38116, Braunschweig, Germany
    Mycotoxin Res 30:161-70. 2014
    ..The conjugation degree for DON in blood and bile was not influenced by treatments. In conclusion, endotoxemic pigs are characterized by higher DON residue levels in blood, liver, and kidney, probably by a compromised elimination. ..
  11. doi request reprint Ascaridia galli infection affects pullets differently when feed is contaminated with the Fusarium toxin deoxynivalenol (DON)
    S Danicke
    Institute of Animal Nutrition, Friedrich Loeffler Institute FLI, Federal Research Institute for Animal Health, Braunschweig, Germany Electronic address
    Vet Parasitol 198:351-63. 2013
    ..galli might increase the susceptibility towards DON as indicated by an increased DON absorption rate and a compromised antibody formation. The effects of DON on fecundity and worm morphology require further examination...
  12. doi request reprint Hydrothermal treatment of naturally contaminated maize in the presence of sodium metabisulfite, methylamine and calcium hydroxide; effects on the concentration of zearalenone and deoxynivalenol
    Inga Rempe
    Institute of Animal Nutrition, Friedrich Loeffler Institute FLI, Federal Research Institute for Animal Health, Braunschweig, Germany
    Mycotoxin Res 29:169-75. 2013
    ....
  13. doi request reprint The plasma clearance of the Fusarium toxin deoxynivalenol (DON) is decreased in endotoxemic pigs
    Sven Dänicke
    Institute of Animal Nutrition, Friedrich Loeffler Institute FLI, Federal Research Institute for Animal Health, Braunschweig, Germany
    Food Chem Toxicol 50:4405-11. 2012
    ..Whether the higher plasma DON concentrations in endotoxemic pigs are due to a hemodynamically associated longer persistence of the DON glucuronide or because of an altered glucuronidation activity needs to be examined further...
  14. ncbi request reprint On the specific and unspecific effects of a polymeric glucomannan mycotoxin adsorbent on piglets when fed with uncontaminated or with Fusarium toxins contaminated diets
    Sven Dänicke
    Institute of Animal Nutrition, Federal Agricultural Research Centre FAL, Braunschweig, Germany
    Arch Anim Nutr 61:266-75. 2007
    ....
  15. doi request reprint No carry over of unmetabolised deoxynivalenol in milk of dairy cows fed high concentrate proportions
    Christina Keese
    Institute of Animal Nutrition, Friedrich Loeffler Institute FLI, Federal Research Institute for Animal Health, Braunschweig, Germany
    Mol Nutr Food Res 52:1514-29. 2008
    ..0001 and 0.0011) but significantly higher in Group Myco-30 than in Group Myco-60. This effect may result from an altered bioavailability of DON from maize silage which made up a higher proportion of the daily ration...
  16. doi request reprint Effect of different storage conditions on the mycotoxin contamination of Fusarium culmorum-infected and non-infected wheat straw
    Dirk Rohweder
    Institute of Animal Nutrition, Friedrich Loeffler Institute FLI Federal Research Institute for Animal Health, Bundesallee 50, 38116, Braunschweig, Germany
    Mycotoxin Res 27:145-53. 2011
    ....
  17. doi request reprint Effects of increasing concentrations of sodium metabisulphite (Na2S 2O 5, SBS) on deoxynivalenol (DON) concentration and microbial spoilage of triticale kernels preserved without and with propionic acid at various moisture contents
    Sven Dänicke
    Institute of Animal Nutrition, Friedrich Loeffler Institute FLI, Federal Research Institute for Animal Health, Bundesallee 50, 38116, Braunschweig, Germany
    Mycotoxin Res 25:215-23. 2009
    ....
  18. doi request reprint Systemic and local effects of the Fusarium toxin deoxynivalenol (DON) are not alleviated by dietary supplementation of humic substances (HS)
    Sven Dänicke
    Institute of Animal Nutrition, Friedrich Loeffler Institute FLI, Federal Research Institute for Animal Health, Braunschweig, Germany
    Food Chem Toxicol 50:979-88. 2012
    ..These changes had no consequences for nutrient digestibility or LPS levels in systemic blood (0.02-0.08 EU/mL). As portal LPS levels were not measured, FUS effects on intestinal LPS translocation cannot be excluded...
  19. doi request reprint Diagnosis of intoxications of piglets fed with Fusarium toxin-contaminated maize by the analysis of mycotoxin residues in serum, liquor and urine with LC-MS/MS
    Ulrike Brezina
    a Institute of Animal Nutrition, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Braunschweig, Germany
    Arch Anim Nutr 68:425-47. 2014
    ..Effects of the duration of toxin exposure within the feeding groups were observed for ZEN, DON and de-DON in all specimens as well as for α-ZEL, β-ZEL and ZAN in urine...
  20. doi request reprint Development of a liquid chromatography tandem mass spectrometry method for the simultaneous determination of zearalenone, deoxynivalenol and their metabolites in pig serum
    Ulrike Brezina
    Institute of Animal Nutrition, Federal Research Institute for Animal Health, Friedrich Loeffler Institut, Braunschweig, Germany
    Mycotoxin Res 30:171-86. 2014
    ..This method is precise and reproducible and can be used as a multi-biomarker method to assess animal exposure to these mycotoxins and for diagnosis of intoxications. ..
  21. doi request reprint UV-induced cis-trans isomerization of zearalenone in contaminated maize
    Ulrike Brezina
    Institute of Animal Nutrition, Friedrich Loeffler Institut FLI, Federal Research Institute for Animal Health, Bundesallee 50, 38116, Braunschweig, Germany
    Mycotoxin Res 29:221-7. 2013
    ..The consequence of this finding for practical liquid feeding systems for pigs requires further investigation. Additionally, an improvement of the analytical method for cis-ZEN determination is needed. ..
  22. doi request reprint Determination of very low stable isotope enrichments of [(2)H(5)]-phenylalanine in chicken liver using liquid chromatography-tandem mass spectrometry (LC-MS/MS)
    Katrin Wilkerling
    Institute of Animal Nutrition, Friedrich Loeffler Institut FLI, Federal Research Institute for Animal Health, Bundesallee 50, 38116 Braunschweig, Germany
    J Chromatogr B Analyt Technol Biomed Life Sci 911:147-53. 2012
    ..Compared to GC-MS, the main advantages of the LC-MS/MS method are its higher selectivity as well as the elimination of the need to convert and derivatize the samples prior to measuring...
  23. doi request reprint Residues of deoxynivalenol (DON) and its metabolite de-epoxy-DON in eggs, plasma and bile of laying hens of different genetic backgrounds
    Mohammad Ebrahem
    a Institute of Animal Nutrition, Friedrich Loeffler Institute FLI, Federal Research Institute for Animal Health, Braunschweig, Germany
    Arch Anim Nutr 68:412-22. 2014
    ..These results show that very low levels of DON were transferred into eggs and indicate that although eggs could contribute to human exposure to DON, the levels are very low and insignificant...
  24. doi request reprint Effects of feeding deoxynivalenol (DON)-contaminated wheat to laying hens and roosters of different genetic background on the reproductive performance and health of the newly hatched chicks
    Mohammad Ebrahem
    Institute of Animal Nutrition, Friedrich Loeffler Institute FLI, Federal Research Institute for Animal Health, Bundesallee 50, 38116, Brunswick, Germany
    Mycotoxin Res 30:131-40. 2014
    ....
  25. doi request reprint On the effects of the Fusarium toxin deoxynivalenol (DON) administered per os or intraperitoneal infusion to sows during days 63 to 70 of gestation
    Tanja Goyarts
    Institute of Animal Nutrition, Friedrich Loeffler Institute FLI, Federal Research Institute for Animal Health, Bundesallee 50, 38116, Braunschweig, Germany
    Mycotoxin Res 26:119-31. 2010
    ....
  26. ncbi request reprint On the effects of graded levels of Fusarium toxin contaminated wheat in diets for gilts on feed intake, growth performance and metabolism of deoxynivalenol and zearalenone
    Sven Dänicke
    Institute of Animal Nutrition, Federal Agricultural Research Centre Braunschweig, Bundesallee 50, D 38116 Braunschweig, Germany
    Mol Nutr Food Res 49:932-43. 2005
    ..The maximum ratio between DON concentration in liver and diet was 0.0013, and suggests that a possible contamination of pig liver with DON is negligible and does not contribute significantly to human DON exposure...
  27. doi request reprint Determination of T-2 toxin, HT-2 toxin, and three other type A trichothecenes in layer feed by high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS)--comparison of two sample preparation methods
    Katrin Bernhardt
    Institute of Animal Nutrition, Friedrich Loeffler Institute FLI, Federal Research Institute for Animal Health, Bundesallee 50, 38116, Braunschweig, Germany
    Mycotoxin Res 32:89-97. 2016
    ....
  28. doi request reprint Development of a multi-toxin method for investigating the carryover of zearalenone, deoxynivalenol and their metabolites into milk of dairy cows
    Janine Winkler
    a Institute of Animal Nutrition, Friedrich Loeffler Institute FLI, Federal Research Institute for Animal Health, Braunschweig, Germany
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 32:371-80. 2015
    ..0017 for DON independent of exposure. It can be concluded that dietary toxin concentrations in the feed below or close to the current guidance values do not pose a risk for consumers due to negligible carryover rates...