Roland Hetzer

Summary

Affiliation: Deutsches Herzzentrum Berlin
Country: Germany

Publications

  1. pmc Cryopreservation of human vascular umbilical cord cells under good manufacturing practice conditions for future cell banks
    Bianca Polchow
    German Heart Institute Berlin, Department of Cardiothoracic and Vascular Surgery, Laboratory for Tissue Engineering, Augustenburger Platz 1, 13353 Berlin, Germany
    J Transl Med 10:98. 2012
  2. pmc Urine hepcidin has additive value in ruling out cardiopulmonary bypass-associated acute kidney injury: an observational cohort study
    Anja Haase-Fielitz
    Department of Nephrology and Hypertension and Endocrinology and Metabolic Diseases, Otto von Guericke University, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    Crit Care 15:R186. 2011
  3. pmc Sex-specific modification of progesterone receptor expression by 17β-oestradiol in human cardiac tissues
    Georgios Kararigas
    Institute of Gender in Medicine, Charité Medical University, Hessische Strasse 3 4, 10115 Berlin, Germany
    Biol Sex Differ 1:2. 2010
  4. pmc Preamplification techniques for real-time RT-PCR analyses of endomyocardial biopsies
    Michel Noutsias
    Department of Cardiology and Pneumonology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, 12200 Berlin, Germany
    BMC Mol Biol 9:3. 2008
  5. ncbi request reprint Technology insight: Use of ventricular assist devices in children
    Roland Hetzer
    Department of Thoracic and Cardiovascular Surgery, Deutsches Herzzentrum Berlin, Germany
    Nat Clin Pract Cardiovasc Med 3:377-86. 2006
  6. ncbi request reprint Implantation of MicroMed DeBakey VAD through left thoracotomy after previous median sternotomy operations
    Roland Hetzer
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    Ann Thorac Surg 77:347-50. 2004
  7. ncbi request reprint [Heart assist systems--current status]
    Roland Hetzer
    Abteilung für Herz, Thorax und Gefasschirurgie, Deutsches Herzzentrum Berlin
    Herz 27:407-17. 2002
  8. doi request reprint Single-center experience with treatment of cardiogenic shock in children by pediatric ventricular assist devices
    Roland Hetzer
    Deutsches Herzzentrum, Berlin, Germany
    J Thorac Cardiovasc Surg 141:616-23, 623.e1. 2011
  9. ncbi request reprint First experiences with a novel magnetically suspended axial flow left ventricular assist device
    Roland Hetzer
    Department of Cardiothoracic and Vascular Surgery, Augustenburger Platz 1, Deutsches Herzzentrum Berlin, 13353 Berlin, Germany
    Eur J Cardiothorac Surg 25:964-70. 2004
  10. doi request reprint Remodeling of aortic root by annular reconstruction and plication of sinuses of Valsalva
    Roland Hetzer
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    J Card Surg 23:49-51. 2008

Collaborators

Detail Information

Publications210 found, 100 shown here

  1. pmc Cryopreservation of human vascular umbilical cord cells under good manufacturing practice conditions for future cell banks
    Bianca Polchow
    German Heart Institute Berlin, Department of Cardiothoracic and Vascular Surgery, Laboratory for Tissue Engineering, Augustenburger Platz 1, 13353 Berlin, Germany
    J Transl Med 10:98. 2012
    ..Therefore, the establishment of a future human vascular cell bank conforming to good manufacturing practice (GMP) conditions is desirable for therapeutic applications such as tissue engineered cardiovascular constructs...
  2. pmc Urine hepcidin has additive value in ruling out cardiopulmonary bypass-associated acute kidney injury: an observational cohort study
    Anja Haase-Fielitz
    Department of Nephrology and Hypertension and Endocrinology and Metabolic Diseases, Otto von Guericke University, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    Crit Care 15:R186. 2011
    ..Recently, interest has focused on hepcidin, a regulator of iron homeostasis, as a unique renal biomarker...
  3. pmc Sex-specific modification of progesterone receptor expression by 17β-oestradiol in human cardiac tissues
    Georgios Kararigas
    Institute of Gender in Medicine, Charité Medical University, Hessische Strasse 3 4, 10115 Berlin, Germany
    Biol Sex Differ 1:2. 2010
    ..We selected the progesterone receptor as a well studied 17β-oestradiol target that may be pathologically linked to cardiac remodelling...
  4. pmc Preamplification techniques for real-time RT-PCR analyses of endomyocardial biopsies
    Michel Noutsias
    Department of Cardiology and Pneumonology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, 12200 Berlin, Germany
    BMC Mol Biol 9:3. 2008
    ..We applied two preamplification techniques, the TaqMan(R) PreAmp Master Mix (T-PreAmp) and a multiplex preamplification following a sequence specific reverse transcription (SSRT-PreAmp)...
  5. ncbi request reprint Technology insight: Use of ventricular assist devices in children
    Roland Hetzer
    Department of Thoracic and Cardiovascular Surgery, Deutsches Herzzentrum Berlin, Germany
    Nat Clin Pract Cardiovasc Med 3:377-86. 2006
    ..In this review we present current VAD experience in children in the light of improvements in decision making, device technology, implantation techniques, and in coagulation monitoring and anticoagulation...
  6. ncbi request reprint Implantation of MicroMed DeBakey VAD through left thoracotomy after previous median sternotomy operations
    Roland Hetzer
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    Ann Thorac Surg 77:347-50. 2004
    ..This approach avoids reopening the chest through a median sternotomy and reduces the risk of bleeding and subsequent complications...
  7. ncbi request reprint [Heart assist systems--current status]
    Roland Hetzer
    Abteilung für Herz, Thorax und Gefasschirurgie, Deutsches Herzzentrum Berlin
    Herz 27:407-17. 2002
    ..While heart transplantation has proven to provide excellent long-term results with 10-year survival rates at 50%, it will remain a casuistic therapy, limited by the comparatively small number of procedures which can be performed...
  8. doi request reprint Single-center experience with treatment of cardiogenic shock in children by pediatric ventricular assist devices
    Roland Hetzer
    Deutsches Herzzentrum, Berlin, Germany
    J Thorac Cardiovasc Surg 141:616-23, 623.e1. 2011
    ..We present our nearly 20-year experience with pediatric ventricular assist devices...
  9. ncbi request reprint First experiences with a novel magnetically suspended axial flow left ventricular assist device
    Roland Hetzer
    Department of Cardiothoracic and Vascular Surgery, Augustenburger Platz 1, Deutsches Herzzentrum Berlin, 13353 Berlin, Germany
    Eur J Cardiothorac Surg 25:964-70. 2004
    ..The present report summarizes the clinical experience with patients treated for severe cardiogenic shock for the first time with a newly developed axial flow pump with magnetically levitated bearings...
  10. doi request reprint Remodeling of aortic root by annular reconstruction and plication of sinuses of Valsalva
    Roland Hetzer
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    J Card Surg 23:49-51. 2008
    ..The aortic root is wrapped with the Valsalva vascular graft, the distal aortic root is sutured to the vascular graft, and the aortic annulus is thus stabilized at the sinotubular junction...
  11. ncbi request reprint Improvement in survival after mechanical circulatory support with pneumatic pulsatile ventricular assist devices in pediatric patients
    Roland Hetzer
    Deutsches Herzzentrum Berlin, Berlin, Germany
    Ann Thorac Surg 82:917-24; discussion 924-5. 2006
    ....
  12. ncbi request reprint Bridging-to-recovery
    R Hetzer
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum, Berlin, Germany
    Ann Thorac Surg 71:S109-13; discussion S114-5. 2001
    ..In a subgroup of selected patients, some hearts recovered considerable function. In these patients the device was removed and cardiac transplantation was no longer necessary. We report our long-term experience with these weaned patients...
  13. ncbi request reprint Midterm follow-up of patients who underwent removal of a left ventricular assist device after cardiac recovery from end-stage dilated cardiomyopathy
    R Hetzer
    Deutsches Herzzentrum, Berlin, Germany
    J Thorac Cardiovasc Surg 120:843-53. 2000
    ..We report the case histories of patients who underwent removal of the device more than 4 years ago...
  14. ncbi request reprint Daily noninvasive rejection monitoring improves long-term survival in pediatric heart transplantation
    R Hetzer
    Department of Cardiac, Thoracic and Vascular Surgery, Congenital Heart Diseases, Deutsches Herzzentrum Berlin, Germany
    Ann Thorac Surg 66:1343-9. 1998
    ..Day-by-day surveillance of the heart and prompt treatment of any rejection may yield improved long-term survival...
  15. ncbi request reprint Circulatory support with pneumatic paracorporeal ventricular assist device in infants and children
    R Hetzer
    Department of Cardiac, Thoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Germany
    Ann Thorac Surg 66:1498-506. 1998
    ..Since 1994 the blood-contacting surfaces of the device system have been heparin-coated. In this report the experiences with VAD support in 28 children are presented...
  16. doi request reprint Regional differences in tissue oxygenation during cardiopulmonary bypass for correction of congenital heart disease in neonates and small infants: relevance of near-infrared spectroscopy
    Mathias Redlin
    Department of Anesthesia, Deutsches Herzzentrum Berlin, Berlin, Germany
    J Thorac Cardiovasc Surg 136:962-7. 2008
    ..Moreover, we evaluated potential benefits of near-infrared spectroscopic monitoring of regional tissue oxygenation...
  17. doi request reprint Is bridge to recovery more likely with pulsatile left ventricular assist devices than with nonpulsatile-flow systems?
    Thomas Krabatsch
    German Heart Institute Berlin, Berlin, Germany
    Ann Thorac Surg 91:1335-40. 2011
    ..With the broad application of continuous-flow pumps, we observed a decrease in the numbers of possible LVAD explanations due to myocardial recovery in these particular patients. We investigated this phenomenon and its causes...
  18. doi request reprint New 29-mm balloon-expandable prosthesis for transcatheter aortic valve implantation in large annuli
    Axel Unbehaun
    Deutsches Herzzentrum Berlin, Berlin, Germany
    Ann Thorac Surg 95:1982-90. 2013
    ..This study sought to define ranges of safe applicability in terms of device landing zone geometry. A second purpose was to determine performance of the prosthesis and clinical outcome...
  19. doi request reprint Extracorporeal membrane oxygenation for intraoperative cardiac support in children with congenital heart disease
    Eva Maria Delmo Walter
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    Interact Cardiovasc Thorac Surg 10:753-8. 2010
    ..We report our experience in pediatric patients supported by ECMO for intraoperative cardiac failure between November 1991 and December 2006...
  20. doi request reprint Biomarker responses during mid-term mechanical cardiac support in children
    Grit Heise
    Department of Congenital Heart Disease, Deutsches Herzzentrum Berlin, Berlin, Germany
    J Heart Lung Transplant 27:150-7. 2008
    ..The purpose of this study was to determine the effect of mid-term mechanical circulatory support on the natriuretic hormone system in children and to assess whether such changes are associated with myocardial recovery...
  21. doi request reprint Transapical aortic valve implantation: learning curve with reduced operating time and radiation exposure
    Giuseppe D'Ancona
    Deutsches Herzzentrum Berlin, Berlin, Germany
    Ann Thorac Surg 97:43-7. 2014
    ..The purpose of this study was to test whether, and in which terms, the cumulative institutional experience in the field of transapical transcatheter aortic valve implantation (TAVI) might impact upon operative time and radiation exposure...
  22. doi request reprint Simultaneous aortic valve replacement in left ventricular assist device recipients: single-center experience
    Nikolay Dranishnikov
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    Int J Artif Organs 35:489-94. 2012
    ..We analyzed our recent experience with left ventricular assist device implantation and concomitant aortic valve replacement...
  23. ncbi request reprint Surgical treatment of right-sided active infective endocarditis with or without involvement of the left heart: 20-year single center experience
    Michele Musci
    Deutsches Herzzentrum Berlin, Department of Cardiothoracic and Vascular Surgery, Berlin, Germany
    Eur J Cardiothorac Surg 32:118-25. 2007
    ....
  24. doi request reprint Surgical therapy in patients with active infective endocarditis: seven-year single centre experience in a subgroup of 255 patients treated with the Shelhigh stentless bioprosthesis
    Michele Musci
    Deutsches Herzzentrum Berlin, Department of Cardiothoracic and Vascular Surgery, Augustenburger Platz 1, Berlin, Germany
    Eur J Cardiothorac Surg 34:410-7. 2008
    ..We aimed to identify independent risk factors for early mortality...
  25. doi request reprint High-dose aprotinin effectively reduces blood loss during on-pump coronary artery bypass grafting with bivalirudin anticoagulation
    Andreas Koster
    Department of Anesthesia, Deutsches Herzzentrum, Berlin, Germany
    J Thorac Cardiovasc Surg 135:685-7. 2008
  26. doi request reprint Further experience with the "no-react" bioprosthesis in patients with active infective endocarditis: 11-year single center results in 402 patients
    Michele Musci
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    Thorac Cardiovasc Surg 61:398-408. 2013
    ..1%). Mean follow-up was 2.8 ± 3.2 years (1 month to 11.4 years) with 1,124 patient years, completed in 97.1%. This retrospective study analyzes both prospectively updated data (n = 255) and patients recently operated upon (n = 147)...
  27. doi request reprint Salvage therapy for relapsed posttransplant lymphoproliferative disorders (PTLD) with a second progression of PTLD after Upfront chemotherapy: the role of single-agent rituximab
    Ralf U Trappe
    Department of Hematology and Oncology, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany
    Transplantation 84:1708-12. 2007
    ..Single-agent rituximab salvage therapy is an effective treatment option in this setting of intensively pretreated patients, with virtually no therapy-associated toxicity...
  28. doi request reprint Patient-prosthesis mismatch after transapical aortic valve implantation: incidence and impact on survival
    Marian Kukucka
    Deutsches Herzzentrum Berlin, Charite Campus Benjamin Franklin, Berlin, Germany
    J Thorac Cardiovasc Surg 145:391-7. 2013
    ..The objective of our study was to evaluate P-PM incidence and its impact on survival in a large cohort of patients treated with TAVI...
  29. doi request reprint Repair of anomalous origin of the left coronary artery from the pulmonary artery in infants and children
    Vladimir Alexi-Meskishvili
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    J Thorac Cardiovasc Surg 142:868-74. 2011
    ..Although mortality after direct aortic reimplantation for anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) has significantly decreased, many questions remain unanswered...
  30. ncbi request reprint Bivalirudin during cardiopulmonary bypass in patients with previous or acute heparin-induced thrombocytopenia and heparin antibodies: results of the CHOOSE-ON trial
    Andreas Koster
    Department of Anesthesia, Deutsches Herzzentrum Berlin, Germany
    Ann Thorac Surg 83:572-7. 2007
    ....
  31. ncbi request reprint Aortic root abscess and secondary infective mitral valve disease: results of surgical endocarditis treatment
    Henryk Siniawski
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Eur J Cardiothorac Surg 27:434-40. 2005
    ..Among them were 53 (25.5% of all patients) who were diagnosed as having secondary infective mitral valve disease (SMVD). Mean age was 53+/-14.2 years; there were 37 men and 16 women...
  32. doi request reprint Body mass index and outcome after ventricular assist device placement
    Michele Musci
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Germany
    Ann Thorac Surg 86:1236-42. 2008
    ..Many patients with congestive heart failure develop cardiac cachexia. In this study the association between BMI and outcomes after VAD implantation was investigated...
  33. doi request reprint Transcatheter aortic valve implantation into a stentless prosthetic valve with a low position of the left main coronary artery
    Giuseppe D'Ancona
    Deutsches Herzzentrum Berlin, Berlin, Germany
    Heart Surg Forum 15:E268-71. 2012
    ..It was difficult to decide whether to perform atypical TAVI or to convert to conventional redo aortic valve surgery in an extremely high-risk patient with a degenerated stentless aortic bioprosthesis...
  34. doi request reprint Pediatric heart transplantation: 23-year single-center experience
    Michael Huebler
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    Eur J Cardiothorac Surg 39:e83-9. 2011
    ..Nevertheless early and late morbidity and mortality are influenced by acute rejection, cardiac allograft vasculopathy (CAV), malignancy, renal failure, and graft failure...
  35. doi request reprint Rupture of the device landing zone during transcatheter aortic valve implantation: a life-threatening but treatable complication
    Miralem Pasic
    Deutsches Herzzentrum Berlin, Berlin, Germany
    Circ Cardiovasc Interv 5:424-32. 2012
    ..It is mostly considered difficult to treat or even untreatable...
  36. ncbi request reprint In vitro fabrication of a tissue engineered human cardiovascular patch for future use in cardiovascular surgery
    Chao Yang
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Germany
    Ann Thorac Surg 81:57-63. 2006
    ..In this experiment, we developed a pulsatile flow system that provides biochemical and biomechanical signals in order to regulate autologous, human patch-tissue development in vitro...
  37. doi request reprint Minimizing intraoperative hemodilution by use of a very low priming volume cardiopulmonary bypass in neonates with transposition of the great arteries
    Matthias Redlin
    Department of Anesthesiology, German Heart Institute, Berlin, Germany
    J Thorac Cardiovasc Surg 142:875-81. 2011
    ....
  38. doi request reprint [Technical possibilities and limitations of mechanical circulatory support]
    Thomas Krabatsch
    Klinik für Herz Thorax und Gefäßchirurgie, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13353 Berlin
    Anasthesiol Intensivmed Notfallmed Schmerzther 46:414-21; quiz 422. 2011
    ..Although there are different devices available, patient selection, preoperative and intraoperative management, and the timing of VAD implantation are the elements critical to successful circulatory support...
  39. doi request reprint Elective femoro-femoral cardiopulmonary bypass during transcatheter aortic valve implantation: a useful tool
    Thorsten Drews
    Deutsches Herzzentrum Berlin, Berlin, Germany
    J Thorac Cardiovasc Surg 145:757-63. 2013
    ..Nevertheless, this new procedure has some potential risks, especially during the phases of rapid pacing (valvuloplasty and valve deployment). The use of cardiopulmonary bypass allows the perioperative risk to be reduced...
  40. ncbi request reprint Pre-explant stability of unloading-promoted cardiac improvement predicts outcome after weaning from ventricular assist devices
    Michael Dandel
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Germany
    Circulation 126:S9-19. 2012
    ..However, some patients with LVEF >45 before VAD explantation show early recurrence of heart failure (HF). We aimed to find out if unstable improvement can be recognized before VAD explantation...
  41. doi request reprint Transapical aortic valve implantation: incidence and predictors of paravalvular leakage and transvalvular regurgitation in a series of 358 patients
    Axel Unbehaun
    Deutsches Herzzentrum Berlin, Augustenburger Platz 1, Berlin, Germany
    J Am Coll Cardiol 59:211-21. 2012
    ..The aim of this study was to evaluate the results when the surgical concept of not accepting intraprocedural paravalvular leakage was applied for transcatheter aortic valve implantation (TAVI)...
  42. pmc Transapical transcatheter aortic valve replacement in patients with cardiogenic shock
    Giuseppe D'Ancona
    German Heart Institute Berlin, Berlin, Germany
    Interact Cardiovasc Thorac Surg 14:426-30. 2012
    ..02; P = 0.04). TAVI in patients who are in cardiogenic shock is feasible. Although the early and late outcomes are encouraging, a structured strategy should be developed and further experience is needed...
  43. ncbi request reprint Pneumatic pulsatile ventricular assist devices in children under 1 year of age
    Brigitte Stiller
    Department of Pediatric Cardiology, Deutsches Herzzentrum Berlin, 13353 Berlin, Germany
    Eur J Cardiothorac Surg 28:234-9. 2005
    ..Miniaturized devices and innovative modalities need to be optimized. We report on our experience...
  44. ncbi request reprint Successful use of bivalirudin as anticoagulant for ECMO in a patient with acute HIT
    Andreas Koster
    Department of Anesthesia, Deutsches Herzzentrum Berlin, Berlin, Germany
    Ann Thorac Surg 83:1865-7. 2007
    ..Surgery was successfully performed with moderate intraoperative and postoperative blood loss and transfusion requirements...
  45. doi request reprint Transapical aortic valve implantation in 175 consecutive patients: excellent outcome in very high-risk patients
    Miralem Pasic
    Deutsches Herzzentrum Berlin, Berlin, Germany
    J Am Coll Cardiol 56:813-20. 2010
    ..The aim of this study was to evaluate the outcome of transapical aortic valve implantation in a single center with expanded procedural experience and to compare it with predicted risk for conventional aortic valve surgery...
  46. doi request reprint Trans-apical aortic valve implantation in patients with severe calcification of the ascending aorta
    Semih Buz
    Deutsches Herzzentrum Berlin, Berlin, Germany
    Eur J Cardiothorac Surg 40:463-8. 2011
    ..We evaluate the outcome of trans-apical aortic valve implantation in patients with severely calcified ascending aorta in a single center with expanded procedural experience...
  47. doi request reprint Transapical aortic valve implantation after previous heart surgery
    Thorsten Drews
    Deutsches Herzzentrum Berlin, Berlin, Germany
    Eur J Cardiothorac Surg 39:625-30. 2011
    ....
  48. pmc Combined elective percutaneous coronary intervention and transapical transcatheter aortic valve implantation
    Miralem Pasic
    German Heart Center, Berlin, Germany
    Interact Cardiovasc Thorac Surg 14:463-8. 2012
    ..3%, respectively. The results showed that the single-stage approach with combined elective PCI and TAVI is feasible and safe. It has become our primary choice for treatment of high-risk patients with severe aortic valve stenosis and CAD...
  49. doi request reprint Transapical aortic valve implantation in patients with severely depressed left ventricular function
    Axel Unbehaun
    Deutsches Herzzentrum Berlin, Berlin, Germany
    J Thorac Cardiovasc Surg 143:1356-63. 2012
    ..Transapical aortic valve implantation significantly reduces operative risk in elderly patients with aortic valve stenosis and comorbidities. However, it is unknown whether this procedure is feasible in patients with advanced heart failure...
  50. doi request reprint Repair for active infective atrioventricular valve endocarditis: 23-year single center experience
    Michele Musci
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    Clin Res Cardiol 100:993-1002. 2011
    ..We retrospectively compared early and long-term results of mitral (MV) and tricuspid valve (TV) repair in patients with isolated active infective atrioventricular valve (AV) endocarditis over a period of 23 years...
  51. ncbi request reprint Cardiopulmonary bypass for complex cardiac surgery using bivalirudin anticoagulation in a patient with heparin antibodies
    Michael Huebler
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herssentrum Berlin, Germany
    J Card Surg 21:286-8. 2006
    ..Experience in complicated cases requiring extended cardiopulmonary bypass is limited, however. We report the successful use of bivalirudin in a patient who underwent complex cardiac surgery...
  52. doi request reprint Monitoring of bivalirudin anticoagulation during and after cardiopulmonary bypass using an ecarin-activated TEG system
    Andreas Koster
    Department of Anesthesia, Deutsches Herzzentrum, Berlin, Germany
    J Card Surg 23:321-3. 2008
  53. ncbi request reprint Consumption of blood products during mechanical circulatory support in children: comparison between ECMO and a pulsatile ventricular assist device
    Brigitte Stiller
    Department of Pediatric Cardiology, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Intensive Care Med 30:1814-20. 2004
    ..We compared the coagulation disorders and the need for blood products in children treated either with extracorporeal membrane oxygenation (ECMO) or with the Berlin Heart pulsatile pneumatic ventricular assist device...
  54. ncbi request reprint Repair of ALCAPA in a 4-kg patient followed by successful weaning and "off-pump" explantation of an apical venting pulsatile LVAD
    Michael Huebler
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Germany
    J Card Surg 20:261-3. 2005
    ..The present case demonstrates successful weaning and complete removal of an apical venting pulsatile LVAD in a 4-kg infant without the employment of CPB...
  55. doi request reprint Effect of modified ultrafiltration on bivalirudin elimination and postoperative blood loss after on-pump coronary artery bypass grafting: assessment of different filtration strategies
    Andreas Koster
    Department of Anesthesia, Deutsches Herzzentrum, Berlin, Germany
    J Card Surg 23:655-8. 2008
    ..We assessed the effect of four different strategies of modified ultrafiltration after cardiopulmonary bypass on the bivalirudin elimination and postoperative blood loss...
  56. doi request reprint Prediction of cardiac stability after weaning from left ventricular assist devices in patients with idiopathic dilated cardiomyopathy
    Michael Dandel
    Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Circulation 118:S94-105. 2008
    ..During ventricular assist device (VAD) unloading, cardiac recovery is possible even in patients with chronic heart failure (HF). We sought parameters predictive of cardiac stability after VAD removal...
  57. ncbi request reprint Rheumatic mitral valve repair: 22-year clinical results
    Charles A Yankah
    Deutsches Herzzentrum Berlin, Berlin, Germany
    J Heart Valve Dis 20:257-64. 2011
    ..Comprehensive reproducible repair techniques of the anatomic units in individual patients are required to restore the normal mitral valve anatomy and function...
  58. doi request reprint Transapical aortic valve implantation after previous aortic valve replacement: clinical proof of the "valve-in-valve" concept
    Miralem Pasic
    Deutsches Herzzentrum Berlin, Berlin, Germany
    J Thorac Cardiovasc Surg 142:270-7. 2011
    ..We report the single-center outcome of transapical implantation of aortic valves into degenerated biological aortic valve prostheses ("valve-in-valve") in very high-risk patients...
  59. doi request reprint Analysis of arrhythmias after correction of partial anomalous pulmonary venous connection
    Semih Buz
    Department of Thoracic and Cardiovascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    Ann Thorac Surg 87:580-3. 2009
    ..In this retrospective study, we attempted to determine the incidence of arrhythmias after use of two different techniques for repair of partial anomalous pulmonary venous connection...
  60. doi request reprint Tricuspid incompetence and geometry of the right ventricle as predictors of right ventricular function after implantation of a left ventricular assist device
    Evgenij V Potapov
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    J Heart Lung Transplant 27:1275-81. 2008
    ..Right ventricular (RV) dysfunction develops in 20% to 50% of patients after LVAD implantation, leading to prolonged ICU stay and elevated mortality. However, the prediction of RV failure remains difficult...
  61. pmc Integrated analysis of atrioventricular interactions in tetralogy of Fallot
    Eugénie Riesenkampff
    Deutsches Herzzentrum Berlin, Dept of Congenital Heart Disease and Pediatric Cardiology, Augustenburger Platz 1, Berlin D 13353, Germany
    Am J Physiol Heart Circ Physiol 299:H364-71. 2010
    ..05). In TOF patients, moderate systolic and diastolic right ventricular dysfunction is associated with clearly impaired right atrial function. The left atrium is affected to a lesser extent...
  62. ncbi request reprint Coronary atherosclerosis of the donor heart--impact on early graft failure
    Onnen Grauhan
    Department of Cardiothoracic and Vascular Surgery, German Heart Institute, Augustenburger Platz 1, 13353 Berlin, Germany
    Eur J Cardiothorac Surg 32:634-8. 2007
    ..This study evaluated whether and to what degree pre-existing coronary atherosclerosis may be acceptable...
  63. doi request reprint Transcatheter aortic valve implantation in very high-risk patients with EuroSCORE of more than 40%
    Thorsten Drews
    Deutsches Herzzentrum Berlin, Berlin, Germany
    Ann Thorac Surg 95:85-93. 2013
    ..We analyzed the results of TAVI patients with a EuroSCORE of over 40%...
  64. doi request reprint Effects of a comprehensive blood-sparing approach using body weight-adjusted miniaturized cardiopulmonary bypass circuits on transfusion requirements in pediatric cardiac surgery
    Matthias Redlin
    Department of Anesthesiology, German Heart Institute, Berlin, Germany
    J Thorac Cardiovasc Surg 144:493-9. 2012
    ..We analyzed the effects of this approach on transfusion requirements and risk factors predisposing for blood transfusion...
  65. doi request reprint Preexisting mitral valve prosthesis in patients undergoing left ventricular assist device implantation
    Martin Schweiger
    Deutsches Herzzentrum Berlin, Berlin, Germany
    Artif Organs 36:49-53. 2012
    ..No severe adverse events were observed when the prosthesis was left in place. Attention should be paid to the anticoagulation regime...
  66. ncbi request reprint Changes in exercise capacity, ventilation, and body weight following heart transplantation
    Dirk Habedank
    Division of Applied Cachexia Research, Department of Cardiology, Charite Campus Virchow Klinikum, Berlin, Germany
    Eur J Heart Fail 9:310-6. 2007
    ..Our study prospectively examined changes in these parameters over 24 months following heart transplantation (HTx) and evaluated the potentially confounding effects of weight gain...
  67. pmc Transfusion-free cardiac reoperation in an 11-kg Jehovah's Witness child by use of a minimized cardiopulmonary bypass circuit
    Michael Huebler
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum, D 13353 Berlin, Germany
    Tex Heart Inst J 34:108-11. 2007
    ..The goal of safe, transfusion-free surgery was achieved chiefly by minimizing the priming volume of the cardiopulmonary bypass circuit to 200 mL while providing adequate flow and standard safety features...
  68. ncbi request reprint Homograft reconstruction of the aortic root for endocarditis with periannular abscess: a 17-year study
    Abraham Charles Yankah
    Deutsches Herzzentrum Berlin, Germany
    Eur J Cardiothorac Surg 28:69-75. 2005
    ....
  69. ncbi request reprint Assessment of hemostatic activation during cardiopulmonary bypass for coronary artery bypass grafting with bivalirudin: results of a pilot study
    Andreas Koster
    Department of Anesthesia, Deutsches Herzzentrum Berlin, Berlin, Germany
    J Thorac Cardiovasc Surg 129:1391-4. 2005
    ..This study was conducted to assess the effects of the currently suggested protocol for bivalirudin on hemostatic activation during cardiopulmonary bypass with and without cardiotomy suction...
  70. ncbi request reprint Observational study with everolimus (Certican) in combination with low-dose cyclosporine in de novo heart transplant recipients
    Hans B Lehmkuhl
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    J Heart Lung Transplant 26:700-4. 2007
    ..This observational study reports on immunosuppression with cyclosporine (CsA) in 38 de novo heart transplant recipients receiving everolimus compared with 14 patients receiving mycophenolate mofetil (MMF)...
  71. ncbi request reprint Factors influencing the results of double-valve surgery in patients with fulminant endocarditis: the importance of valve selection
    Henryk Siniawski
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    Heart Surg Forum 7:E405-10. 2004
    ..Extension of infection below the aortic valve is a serious complication, especially with mitral valve involvement. Mortality is substantial and reinfection can strongly influence outcome...
  72. doi request reprint Right-to-left ventricular end-diastolic diameter ratio and prediction of right ventricular failure with continuous-flow left ventricular assist devices
    Marian Kukucka
    Department of Anaesthesiology, Deutsches Herzzentrum, Berlin, Germany
    J Heart Lung Transplant 30:64-9. 2011
    ..This study sought to identify echocardiography parameters to select patients with high risk of RVF after LVAD implantation...
  73. doi request reprint Predictors of early mortality in patients with active infective native or prosthetic aortic root endocarditis undergoing homograft aortic root replacement
    Michele Musci
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    Clin Res Cardiol 98:443-50. 2009
    ..We compared early results of homograft aortic root replacement (ARR) in native (NVE) and prosthetic (PVE) aortic valve endocarditis in order to identify predictors for early mortality (<30 days)...
  74. doi request reprint Surgical treatment for active infective prosthetic valve endocarditis: 22-year single-centre experience
    Michele Musci
    Deutsches Herzzentrum Berlin, Department of Cardiothoracic and Vascular Surgery, Augustenburger Platz 1, 13353 Berlin, Germany
    Eur J Cardiothorac Surg 38:528-38. 2010
    ..We retrospectively analysed the profile and outcome of surgically treated patients with active infective prosthetic valve endocarditis (PVE) over a period of 22 years...
  75. doi request reprint Prediction of survival in patients with cardiogenic shock and multiorgan failure treated with biventricular assist device
    Evgenij V Potapov
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    ASAIO J 56:273-8. 2010
    ..Acidosis and high MODS score predict unfavorable outcome. However, the prediction of clinical outcome in patients in severe cardiogenic shock supported by BVAD is possible in extreme situations only...
  76. doi request reprint Left ventricular assist device or heart transplantation: impact of transpulmonary gradient and pulmonary vascular resistance on decision making
    Elisa Mikus
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    Eur J Cardiothorac Surg 39:310-6. 2011
    ..The aim of the study was to investigate the optimal parameters for treatment decisions and the time course of their potential reversal to normal values during preoperative inotropic support...
  77. doi request reprint Two-dimensional speckle tracking strain analysis for efficacy assessment of myocardial cell therapy
    Boris A Nasseri
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    Cell Transplant 18:361-70. 2009
    ..Thus, 2DSE may be a useful tool for the further development of clinical cardiac cell therapy...
  78. doi request reprint Quilty in biopsy is associated with poor prognosis after heart transplantation
    Nicola Erika Hiemann
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Transpl Immunol 19:209-14. 2008
    ..28-0.77). Quilty is associated with graft loss and poor outcome post HTx. Index biopsy during the first post-transplant year is a useful tool to identify patients at risk and is recommended during routine post-transplant management...
  79. doi request reprint Homograft aortic root replacement in native or prosthetic active infective endocarditis: twenty-year single-center experience
    Michele Musci
    Deutsches Herzzentrum Berlin, Department of Cardiothoracic and Vascular Surgery, Augustenburger Platz1, 13353 Berlin, Germany
    J Thorac Cardiovasc Surg 139:665-73. 2010
    ..We compared early and long-term results of cryopreserved homograft aortic root replacement in native valve endocarditis or prosthetic valve endocarditis associated with periannular abscess...
  80. doi request reprint Regression of myocardial hypertrophy after aortic valve replacement: faster in women?
    George Petrov
    Deutsches Herzzentrum Berlin, Berlin, Germany
    Circulation 122:S23-8. 2010
    ..Female sex and estrogens influence cardiac remodeling and fibrosis in animal models and in men. Sex differences and their molecular mechanisms in hypertrophy regression after aortic valve replacement have not yet been studied...
  81. doi request reprint Transapical aortic valve implantation after previous mitral valve surgery
    Thorsten Drews
    Deutsches Herzzentrum Berlin, Berlin, Germany
    J Thorac Cardiovasc Surg 142:84-8. 2011
    ....
  82. doi request reprint Transapical aortic valve implantation in 194 patients: problems, complications, and solutions
    Miralem Pasic
    Deutsches Herzzentrum Berlin, Berlin, Germany
    Ann Thorac Surg 90:1463-9; discussion 1469-70. 2010
    ..We report our experience during the learning curve for establishing this new method...
  83. ncbi request reprint Intramyocardial delivery of bone marrow mononuclear cells and mechanical assist device implantation in patients with end-stage cardiomyopathy
    Boris A Nasseri
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    Cell Transplant 16:941-9. 2007
    ..Other cell-based strategies should be pursued to harness the potential of cell therapy in LVAD patients...
  84. doi request reprint Quilty indicates increased risk for microvasculopathy and poor survival after heart transplantation
    Nicola E Hiemann
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    J Heart Lung Transplant 27:289-96. 2008
    ..The impact of Quilty (sub-endocardial infiltration of lymphocytes) on the development of stenotic microvasculopathy and outcome after heart transplantation has not yet been evaluated...
  85. doi request reprint A decade of percutaneous coronary interventions in cardiac transplant recipients: a monocentric study in 160 patients
    Ernst Wellnhofer
    Department of Internal Medicine Cardiology, Deutsches Herzzentrum Berlin, Berlin, Germany
    J Heart Lung Transplant 27:17-25. 2008
    ..Percutaneous transluminal coronary angioplasty (PCI) is a method of choice for local revascularization that is also increasingly used in heart transplant patients...
  86. ncbi request reprint Detection of left ventricular asynchrony in patients with right bundle branch block after repair of tetralogy of Fallot using tissue-Doppler imaging-derived strain
    Mohamed Y Abd El Rahman
    Department of Congenital Heart Disease, Deutsches Herzzentrum, Berlin, Germany
    J Am Coll Cardiol 45:915-21. 2005
    ..We aimed to investigate whether patients after tetralogy of Fallot (TOF) repair with right bundle branch block have left ventricular (LV) asynchrony and to assess the influence of ventricular asynchrony on regional and global LV function...
  87. ncbi request reprint Surgical management of acute aortic root endocarditis with viable homograft: 13-year experience
    A C Yankah
    Department of Cardiothoracic and Vascular Surgery, Humboldt University Berlin, Deutsches Herzzentrum Berlin, Augustenburger Platz 1 D 13353 Berlin, Germany
    Eur J Cardiothorac Surg 21:260-7. 2002
    ..The long-term clinical results of geometric mismatched homografts are not well defined and addressed...
  88. ncbi request reprint Shear stress and vascular remodeling: study of cardiac allograft coronary artery disease as a model of diffuse atherosclerosis
    Ernst Wellnhofer
    Departments of Internal Medicine Cardiology, Deutsches Herzzentrum Berlin, Berlin, Germany
    J Heart Lung Transplant 21:405-16. 2002
    ..Flow-dependent remodeling is regulated by shear stress. Thus, normal levels of shear stress at baseline flow reflect adequate regulation and provide a functional assessment of flow-dependent remodeling...
  89. ncbi request reprint Nitric oxide inhalation modulates endothelin-1 plasma concentration gradients following left ventricular assist device implantation
    Frank Wagner
    Deutsches Herzzentrum Berlin, Germany
    J Cardiovasc Pharmacol 44:S89-91. 2004
    ..This provides further evidence that intermittent iNO therapy may modulate ET-1 after LVAD implantation...
  90. ncbi request reprint [Levosimendan-long-term inodilation in an infant with myocardial infarction]
    Y C Luther
    Abteilung für Angeborene Herzfehler, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Z Kardiol 93:234-9. 2004
    ..This case may suggest the use of Levosimendan as a long-term inotropic agent and pulmonary vasodilator in children with depressed cardiac function...
  91. ncbi request reprint Uric acid and survival in chronic heart failure: validation and application in metabolic, functional, and hemodynamic staging
    Stefan D Anker
    Applied Cachexia Research Unit, Charite, Campus Virchow Klinikum, Berlin, Germany
    Circulation 107:1991-7. 2003
    ..Serum uric acid (UA) could be a valid prognostic marker and useful for metabolic, hemodynamic, and functional (MFH) staging in chronic heart failure (CHF)...
  92. ncbi request reprint Arterial switch procedure for D-transposition of the great arteries: quantitative midterm evaluation of hemodynamic changes with cine MR imaging and phase-shift velocity mapping-initial experience
    M Gutberlet
    Department of Radiology, Charite, Campus Virchow Klinikum, Medizinische Fakultät der Humboldt Universität, Augustenburger Platz 1, 13353 Berlin, Germany
    Radiology 214:467-75. 2000
    ....
  93. doi request reprint Genetic deletion of arginine 14 in phospholamban causes dilated cardiomyopathy with attenuated electrocardiographic R amplitudes
    Maximilian G Posch
    Experimental and Clinical Research Center ECRC, Berlin, Germany
    Heart Rhythm 6:480-6. 2009
    ..Thus, identification of disease-causing mutations is a challenging and time-consuming task. Genotype-phenotype associations may alleviate identification of the underlying mutation...
  94. ncbi request reprint Tissue engineering of autologous human heart valves using cryopreserved vascular umbilical cord cells
    Ralf Sodian
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Germany
    Ann Thorac Surg 81:2207-16. 2006
    ....
  95. ncbi request reprint Initial experience with miniature axial flow ventricular assist devices for postcardiotomy heart failure
    Michael J Jurmann
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    Ann Thorac Surg 77:1642-7. 2004
    ....
  96. ncbi request reprint Outpatients on mechanical circulatory support
    Thorsten N H Drews
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    Ann Thorac Surg 75:780-5; discussion 785. 2003
    ..Anticipating increased long-term MCS, a policy to discharge patients home has been instituted. This study compares the results of outpatient on MCS to a group of patients remaining hospitalized...
  97. ncbi request reprint Unusual tumor in the left ventricular outflow tract
    Aref Amiri
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
    Ann Thorac Surg 85:315-7. 2008
    ..We report an unusual case of a pseudocyst in the left ventricular outflow tract in a 58-year-old woman. The cyst was successfully resected by a transatrial approach...
  98. ncbi request reprint Coagulation management in pediatric mechanical circulatory support
    Thorsten Drews
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Germany
    ASAIO J 53:640-5. 2007
    ..003). Embolic and bleeding complications were seen in both groups, but the incidence was lower in group B. Since, however, thrombogenicity of the systems continues to be their main problem, further improvement of treatment is required...
  99. ncbi request reprint Images in cardiovascular medicine. Intramural dissecting hemorrhage of the myocardium
    Cosima Jahnke
    Department of Internal Medicine Cardiology, German Heart Institute Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Circulation 115:e457-9. 2007
  100. doi request reprint Procalcitonin in patients undergoing cardiopulmonary bypass in open heart surgery-first results of the Procalcitonin in Heart Surgery study (ProHearts)
    M Loebe
    Department of Thoracic and Cardiovascular Surgery, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, D 13353 Berlin, Germany
    Intensive Care Med 26:S193-8. 2000
    ..To investigate procalcitonin (PCT) levels in patients undergoing cardiopulmonary bypass (CPB) in order to assess the prevalence and prognostic capacity of elevated PCT levels following CPB in open heart surgery...
  101. ncbi request reprint Reversibility of cardiac cachexia after heart transplantation
    Dirk Habedank
    Division of Applied Cachexia Research, Department of Cardiology, Charite Campus Virchow Klinikum, Berlin, Germany
    J Heart Lung Transplant 24:1757-62. 2005
    ..We aimed to determine whether cardiac cachexia is reversible after HTx, and investigated differences specific to gender...