Steffen Desch

Summary

Country: Germany

Publications

  1. doi request reprint Low vs. higher-dose dark chocolate and blood pressure in cardiovascular high-risk patients
    Steffen Desch
    Department of Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    Am J Hypertens 23:694-700. 2010
  2. doi request reprint Randomized sham-controlled trial of renal sympathetic denervation in mild resistant hypertension
    Steffen Desch
    From the Medical Clinic II Department of Cardiology, Angiology and Intensive Care Medicine, University Heart Center Lübeck, University of Lubeck, Lubeck, Germany S D, I E, H T and Department of Internal Medicine Cardiology, Heart Center, University of Leipzig, Leipzig, Germany S D, T O, D H, K K, K R, M S, M P, U M, G S, I E, H T, P L
    Hypertension 65:1202-8. 2015
  3. doi request reprint Bypass surgery versus percutaneous coronary intervention for the treatment of unprotected left main disease. A meta-analysis of randomized controlled trials
    S Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Strumpellstrasse 39, Leipzig, Germany
    Herz 38:48-56. 2013
  4. doi request reprint Reliability of myocardial salvage assessment by cardiac magnetic resonance imaging in acute reperfused myocardial infarction
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Strümpellstr 39, 04289 Leipzig, Germany
    Int J Cardiovasc Imaging 28:263-72. 2012
  5. doi request reprint Effect of coronary collaterals on microvascular obstruction as assessed by magnetic resonance imaging in patients with acute ST-elevation myocardial infarction treated by primary coronary intervention
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Germany
    Am J Cardiol 104:1204-9. 2009
  6. doi request reprint Randomized comparison of a polymer-free sirolimus-eluting stent versus a polymer-based paclitaxel-eluting stent in patients with diabetes mellitus: the LIPSIA Yukon trial
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig, Heart Center, Leipzig, Germany
    JACC Cardiovasc Interv 4:452-9. 2011
  7. ncbi request reprint Prevalence and clinical impact of left coronary dominance in patients with aortic stenosis
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    J Heart Valve Dis 20:23-8. 2011
  8. doi request reprint Platelet inhibition and GP IIb/IIIa receptor occupancy by intracoronary versus intravenous bolus administration of abciximab in patients with ST-elevation myocardial infarction
    Steffen Desch
    Department of Internal Medicine Cardiology, Heart Center, University of Leipzig, Strümpellstr 39, 04289, Leipzig, Germany
    Clin Res Cardiol 101:117-24. 2012
  9. pmc Cardiac magnetic resonance imaging parameters as surrogate endpoints in clinical trials of acute myocardial infarction
    Steffen Desch
    University of Leipzig Heart Center, Department of Internal Medicine Cardiology, Leipzig, Germany
    Trials 12:204. 2011
  10. doi request reprint Effect of coronary collaterals on long-term prognosis in patients undergoing primary angioplasty for acute ST-elevation myocardial infarction
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Germany
    Am J Cardiol 106:605-11. 2010

Detail Information

Publications71

  1. doi request reprint Low vs. higher-dose dark chocolate and blood pressure in cardiovascular high-risk patients
    Steffen Desch
    Department of Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    Am J Hypertens 23:694-700. 2010
    ..higher doses of dark chocolate over the course of 3 months...
  2. doi request reprint Randomized sham-controlled trial of renal sympathetic denervation in mild resistant hypertension
    Steffen Desch
    From the Medical Clinic II Department of Cardiology, Angiology and Intensive Care Medicine, University Heart Center Lübeck, University of Lubeck, Lubeck, Germany S D, I E, H T and Department of Internal Medicine Cardiology, Heart Center, University of Leipzig, Leipzig, Germany S D, T O, D H, K K, K R, M S, M P, U M, G S, I E, H T, P L
    Hypertension 65:1202-8. 2015
    ..042). In patients with mild resistant hypertension, renal sympathetic denervation failed to show a significant reduction in the primary end point of 24-hour systolic BP at 6 months between groups in the intention to treat analysis...
  3. doi request reprint Bypass surgery versus percutaneous coronary intervention for the treatment of unprotected left main disease. A meta-analysis of randomized controlled trials
    S Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Strumpellstrasse 39, Leipzig, Germany
    Herz 38:48-56. 2013
    ..We performed a meta-analysis of randomized controlled trials to compare coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) for the treatment of de novo unprotected left main disease...
  4. doi request reprint Reliability of myocardial salvage assessment by cardiac magnetic resonance imaging in acute reperfused myocardial infarction
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Strümpellstr 39, 04289 Leipzig, Germany
    Int J Cardiovasc Imaging 28:263-72. 2012
    ..Further validation studies and trials showing the prognostic value of myocardial salvage by CMRI are needed before routine implementation as a surrogate endpoint in STEMI trials...
  5. doi request reprint Effect of coronary collaterals on microvascular obstruction as assessed by magnetic resonance imaging in patients with acute ST-elevation myocardial infarction treated by primary coronary intervention
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Germany
    Am J Cardiol 104:1204-9. 2009
    ..5% vs 12.2%, p = 0.07). In conclusion, well-developed collaterals before reperfusion by PCI in patients with STEMI are associated with a protective effect on coronary microcirculation...
  6. doi request reprint Randomized comparison of a polymer-free sirolimus-eluting stent versus a polymer-based paclitaxel-eluting stent in patients with diabetes mellitus: the LIPSIA Yukon trial
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig, Heart Center, Leipzig, Germany
    JACC Cardiovasc Interv 4:452-9. 2011
    ....
  7. ncbi request reprint Prevalence and clinical impact of left coronary dominance in patients with aortic stenosis
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    J Heart Valve Dis 20:23-8. 2011
    ....
  8. doi request reprint Platelet inhibition and GP IIb/IIIa receptor occupancy by intracoronary versus intravenous bolus administration of abciximab in patients with ST-elevation myocardial infarction
    Steffen Desch
    Department of Internal Medicine Cardiology, Heart Center, University of Leipzig, Strümpellstr 39, 04289, Leipzig, Germany
    Clin Res Cardiol 101:117-24. 2012
    ....
  9. pmc Cardiac magnetic resonance imaging parameters as surrogate endpoints in clinical trials of acute myocardial infarction
    Steffen Desch
    University of Leipzig Heart Center, Department of Internal Medicine Cardiology, Leipzig, Germany
    Trials 12:204. 2011
    ..Randomized controlled trials of acute myocardial infarction which have used CMR parameters as a primary endpoint are presented...
  10. doi request reprint Effect of coronary collaterals on long-term prognosis in patients undergoing primary angioplasty for acute ST-elevation myocardial infarction
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Germany
    Am J Cardiol 106:605-11. 2010
    ..In conclusion, the presence of a well-developed collateral network before mechanical reperfusion in patients with STEMI is associated with improved long-term survival and lower major adverse cardiovascular event rates...
  11. doi request reprint Effect of cocoa products on blood pressure: systematic review and meta-analysis
    Steffen Desch
    Department of Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    Am J Hypertens 23:97-103. 2010
    ..Cocoa products such as dark chocolate and cocoa beverages may have blood pressure (BP)-lowering properties due to their high content of plant-derived flavanols...
  12. doi request reprint Myocardium at risk in ST-segment elevation myocardial infarction comparison of T2-weighted edema imaging with the MR-assessed endocardial surface area and validation against angiographic scoring
    Georg Fuernau
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    JACC Cardiovasc Imaging 4:967-76. 2011
    ....
  13. doi request reprint Right ventricular injury in ST-elevation myocardial infarction: risk stratification by visualization of wall motion, edema, and delayed-enhancement cardiac magnetic resonance
    Matthias Grothoff
    Department of Radiology, University of Leipzig Heart Center, Leipzig, Germany
    Circ Cardiovasc Imaging 5:60-8. 2012
    ..Aims were to determine the predictors and the prognostic significance of RVI assessed by wall motion abnormalities, edema, myocardial salvage index, and delayed enhancement in acute reperfused STEMI...
  14. doi request reprint Sex differences in myocardial salvage and clinical outcome in patients with acute reperfused ST-elevation myocardial infarction: advances in cardiovascular imaging
    Ingo Eitel
    University of Leipzig, Heart Center, Department of Internal Medicine Cardiology, Leipzig, Germany
    Circ Cardiovasc Imaging 5:119-26. 2012
    ....
  15. ncbi request reprint Optimal timing of invasive angiography in stable non-ST-elevation myocardial infarction: the Leipzig Immediate versus early and late PercutaneouS coronary Intervention triAl in NSTEMI (LIPSIA-NSTEMI Trial)
    Holger Thiele
    Department of Internal Medicine Cardiology, Heart Center, University of Leipzig, Strümpellstr 39, 04289 Leipzig, Germany
    Eur Heart J 33:2035-43. 2012
    ..The aim of this multicentre trial was to assess whether an immediate invasive approach is superior to an early invasive or a selective invasive approach with respect to reduction of large infarction...
  16. doi request reprint Relationship and prognostic value of microvascular obstruction and infarct size in ST-elevation myocardial infarction as visualized by magnetic resonance imaging
    Suzanne de Waha
    Department of Internal Medicine, Cardiology, University of Leipzig Heart Center, Strümpellstr 39, Leipzig, 04289, Germany
    Clin Res Cardiol 101:487-95. 2012
    ..We hypothesized that a ratio of MO and infarct size (MO/infarct size) might be an even stronger predictor for outcome after STEMI, which has not been investigated yet...
  17. doi request reprint Prognostic significance and determinants of myocardial salvage assessed by cardiovascular magnetic resonance in acute reperfused myocardial infarction
    Ingo Eitel
    Heart Center, Department of Internal Medicine Cardiology, University of Leipzig, Leipzig, Germany
    J Am Coll Cardiol 55:2470-9. 2010
    ..The aim of the study was to determine the prognostic significance and determinants of myocardial salvage assessed by cardiovascular magnetic resonance (CMR) in reperfused ST-segment elevation myocardial infarction...
  18. doi request reprint Prognostic value and determinants of a hypointense infarct core in T2-weighted cardiac magnetic resonance in acute reperfused ST-elevation-myocardial infarction
    Ingo Eitel
    University of Leipzig Heart Center, Department of Internal Medicine Cardiology, Leipzig, Germany
    Circ Cardiovasc Imaging 4:354-62. 2011
    ..The aim of this study was to evaluate determinants and prognostic impact of a hypointense infarct core in T2-weighted CMR images, studied in patients after acute, reperfused ST-elevation-myocardial infarction...
  19. doi request reprint Impact of N-acetylcysteine on contrast-induced nephropathy defined by cystatin C in patients with ST-elevation myocardial infarction undergoing primary angioplasty
    Michal Droppa
    Department of Internal Medicine Cardiology, University of Leipzig, Heart Center, Leipzig, Germany
    Clin Res Cardiol 100:1037-43. 2011
    ....
  20. doi request reprint Incidence and distribution of occluded culprit arteries and impact of coronary collaterals on outcome in patients with non-ST-segment elevation myocardial infarction and early invasive treatment strategy
    Philipp Bahrmann
    Department of Internal Medicine Cardiology, University of Leipzig, Heart Center, 04289, Leipzig, Germany
    Clin Res Cardiol 100:457-67. 2011
    ..In addition, coronary collaterals may have beneficial effects in patients with OCA...
  21. doi request reprint Long-term prognostic value of myocardial salvage assessed by cardiovascular magnetic resonance in acute reperfused myocardial infarction
    Ingo Eitel
    Department of Internal Medicine, University of Leipzig, Heart Center, Leipzig, Germany
    Heart 97:2038-45. 2011
    ....
  22. doi request reprint Relation of circulating MicroRNA-133a concentrations with myocardial damage and clinical prognosis in ST-elevation myocardial infarction
    Ingo Eitel
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    Am Heart J 164:706-14. 2012
    ..The aims of this study were (1) to assess the relation between miR-133a and myocardial damage assessed by cardiovascular magnetic resonance (CMR) imaging and (2) to evaluate the prognostic value of miR-133a in reperfused STEMI...
  23. doi request reprint Diagnostic performance of CMR imaging compared with EMB in patients with suspected myocarditis
    Philipp Lurz
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    JACC Cardiovasc Imaging 5:513-24. 2012
    ..The goal of this study was to assess the diagnostic performance of cardiac magnetic resonance (CMR) compared with endomyocardial biopsy in patients with suspected acute myocarditis (AMC) and chronic myocarditis (CMC)...
  24. doi request reprint Time-dependency, predictors and clinical impact of infarct transmurality assessed by magnetic resonance imaging in patients with ST-elevation myocardial infarction reperfused by primary coronary percutaneous intervention
    Suzanne de Waha
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Strümpellstr 39, 04289, Leipzig, Germany
    Clin Res Cardiol 101:191-200. 2012
    ..However, transmural infarction was not predictive of death and congestive heart failure...
  25. doi request reprint Osteoprotegerin in ST-elevation myocardial infarction: prognostic impact and association with markers of myocardial damage by magnetic resonance imaging
    Georg Fuernau
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig Germany
    Int J Cardiol 167:2134-9. 2013
    ..In acute ST-elevation myocardial infarction (STEMI) data on the correlation to myocardial damage by cardiac magnetic resonance imaging (CMR) or clinical outcome are lacking...
  26. doi request reprint Comparison of bare-metal stenting with minimally invasive bypass surgery for stenosis of the left anterior descending coronary artery: 10-year follow-up of a randomized trial
    Stephan Blazek
    Department of Internal Medicine, Cardiology, University of Leipzig Heart Center, Strumpellstrasse 39, Leipzig, Germany
    JACC Cardiovasc Interv 6:20-6. 2013
    ....
  27. doi request reprint Prognostic impact of hyperglycemia in nondiabetic and diabetic patients with ST-elevation myocardial infarction: insights from contrast-enhanced magnetic resonance imaging
    Ingo Eitel
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    Circ Cardiovasc Imaging 5:708-18. 2012
    ....
  28. doi request reprint Intraaortic balloon support for myocardial infarction with cardiogenic shock
    Holger Thiele
    University of Leipzig Heart Center, Department of Internal Medicine Cardiology, Leipzig, Germany
    N Engl J Med 367:1287-96. 2012
    ..However, evidence is based mainly on registry data, and there is a paucity of randomized clinical trials...
  29. doi request reprint Impact of high-dose N-acetylcysteine versus placebo on contrast-induced nephropathy and myocardial reperfusion injury in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. The LIPSIA-
    Holger Thiele
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    J Am Coll Cardiol 55:2201-9. 2010
    ....
  30. doi request reprint Intracoronary versus intravenous bolus abciximab application in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: 6-month effects on infarct size and left ventricular function. The randomised Leipzig I
    Ingo Eitel
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Strümpellstr 39, 04289, Leipzig, Germany
    Clin Res Cardiol 100:425-32. 2011
    ..Aim of this study was to investigate whether the early benefits of an IC abciximab administration in STEMI patients undergoing PCI are sustained at 6 months...
  31. doi request reprint Impact of early vs. late microvascular obstruction assessed by magnetic resonance imaging on long-term outcome after ST-elevation myocardial infarction: a comparison with traditional prognostic markers
    Suzanne de Waha
    Department of Internal Medicine Cardiology, University of Leipzig Heart Centre, Leipzig, Germany
    Eur Heart J 31:2660-8. 2010
    ..Furthermore, it is unclear whether the assessment of MO by MRI adds incremental prognostic information independent of traditional outcome markers...
  32. doi request reprint Effect of aspiration thrombectomy on microvascular obstruction in NSTEMI patients: the TATORT-NSTEMI trial
    Holger Thiele
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany Medical Clinic II, University Hospital Schleswig Holstein, University of Lubeck, Lubeck, Germany Electronic address
    J Am Coll Cardiol 64:1117-24. 2014
    ..There are no trials assessing thrombectomy in non-ST-segment elevation myocardial infarction (NSTEMI) patients...
  33. doi request reprint Growth-differentiation factor 15 as predictor of mortality in acute reperfused ST-elevation myocardial infarction: insights from cardiovascular magnetic resonance
    Ingo Eitel
    Department of Internal Medicine Cardiology, University of Leipzig, Heart Center, Strumpellstrasse 39, Leipzig 04289, Germany
    Heart 97:632-40. 2011
    ....
  34. doi request reprint Randomized comparison of pre-hospital-initiated facilitated percutaneous coronary intervention versus primary percutaneous coronary intervention in acute myocardial infarction very early after symptom onset: the LIPSIA-STEMI trial (Leipzig immediate preho
    Holger Thiele
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    JACC Cardiovasc Interv 4:605-14. 2011
    ....
  35. doi request reprint Shock Index as a Predictor of Myocardial Damage and Clinical Outcome in ST-Elevation Myocardial Infarction
    Sebastian J Reinstadler
    University Heart Center Lübeck, Medical Clinic II, Department of Cardiology, Angiology and Intensive Care Medicine, University of Lubeck
    Circ J 80:924-30. 2016
    ..Furthermore, the relationship of the shock index with myocardial damage is unknown. The aim of this study was to evaluate the association of the shock index with markers of myocardial damage and clinical outcome in patients with STEMI...
  36. doi request reprint Thrombus Aspiration in Patients With ST-Segment Elevation Myocardial Infarction Presenting Late After Symptom Onset
    Steffen Desch
    University Heart Center Lübeck, Medical Clinic II Cardiology Angiology Intensive Care Medicine, University Hospital Schleswig Holstein, Lubeck, Germany German Center for Cardiovascular Research DZHK, partner site Hamburg Kiel Lübeck, Lubeck, Germany Electronic address
    JACC Cardiovasc Interv 9:113-22. 2016
    ....
  37. doi request reprint Angiopoietin-2 in acute myocardial infarction complicated by cardiogenic shock-a biomarker substudy of the IABP-SHOCK II-Trial
    Janine Pöss
    Medical Clinic II Cardiology Angiology Intensive Care Medicine, University Heart Centre Lübeck, University Hospital Schleswig Holstein UKSH, Ratzeburger Allee 160, 23538, Lubeck, Germany
    Eur J Heart Fail 17:1152-60. 2015
    ....
  38. pmc Prognosis after ST-elevation myocardial infarction: a study on cardiac magnetic resonance imaging versus clinical routine
    Suzanne de Waha
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Strümpellstr, 39, 04289 Leipzig, Germany
    Trials 15:249. 2014
    ....
  39. doi request reprint Gender differences in patients with cardiogenic shock complicating myocardial infarction: a substudy of the IABP-SHOCK II-trial
    Karl Fengler
    Department of Internal Medicine, Cardiology, University of Leipzig, Heart Center, Strümpellstraße 39, 04289, Leipzig, Germany
    Clin Res Cardiol 104:71-8. 2015
    ..Aim of this study was therefore to investigate gender-specific differences in a large cohort of AMI patients with CS undergoing contemporary treatment...
  40. doi request reprint Comparison of sirolimus-eluting stenting with minimally invasive bypass surgery for stenosis of the left anterior descending coronary artery: 7-year follow-up of a randomized trial
    Stephan Blazek
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    JACC Cardiovasc Interv 8:30-8. 2015
    ....
  41. pmc Thrombus Aspiration in ThrOmbus containing culpRiT lesions in Non-ST-Elevation Myocardial Infarction (TATORT-NSTEMI): study protocol for a randomized controlled trial
    Suzanne de Waha
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Struempellstr 39, Leipzig 04289, Germany
    Trials 14:110. 2013
    ..Current guidelines recommend thrombus aspiration in patients with ST-elevation myocardial infarction (STEMI); however, there are insufficient data to unequivocally support thrombectomy in patients with non-STEMI (NSTEMI)...
  42. doi request reprint What is the evidence for IABP in STEMI with and without cardiogenic shock?
    Suzanne de Waha
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Strumpellstrasse 39, 04289 Leipzig, Germany
    Ther Adv Cardiovasc Dis 6:123-32. 2012
    ..Although recent meta-analyses challenge current AHA/ACC/ESC guidelines, adequately powered randomized studies are needed to elucidate the role of IABP in patients with acute myocardial infarction complicated by cardiogenic shock...
  43. doi request reprint Timing of invasive treatment after fibrinolysis in ST elevation myocardial infarction--a meta-analysis of immediate or early routine versus deferred or ischemia-guided randomised controlled trials
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Centre, Strümpellstr 39, Leipzig 04289, Germany
    Heart 96:1695-702. 2010
    ..Controversy remains over the optimal timing of percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI) who have initially been treated with fibrinolytic agents...
  44. doi request reprint Prognostic impact of established and novel renal function biomarkers in myocardial infarction with cardiogenic shock: A biomarker substudy of the IABP-SHOCK II-trial
    Georg Fuernau
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany Electronic address
    Int J Cardiol 191:159-66. 2015
    ..However, in high-risk CS patients their role for assessing renal injury has not yet been investigated in comparison to the most widely used serum creatinine...
  45. doi request reprint Cardioprotection by combined intrahospital remote ischaemic perconditioning and postconditioning in ST-elevation myocardial infarction: the randomized LIPSIA CONDITIONING trial
    Ingo Eitel
    University Heart Center Lübeck, Medical Clinic II Cardiology Angiology Intensive Care Medicine, University Hospital Schleswig Holstein, Ratzeburger Allee 160, 23538 Lubeck, Germany German Centre for Cardiovascular Research DZHK, partner site Hamburg Kiel Lübeck, Lubeck, Germany
    Eur Heart J 36:3049-57. 2015
    ..The aim of this study was to evaluate if the co-application of intrahospital RIC and PostC has a more powerful effect on myocardial salvage compared with either PostC alone or control...
  46. doi request reprint Outcome in patients with left-sided native-valve infective endocarditis and isolated large vegetations
    Steffen Desch
    Department of Internal Medicine Cardiology, Angiology, Intensive Care Medicine, University of Luebeck, Luebeck, Germany
    Clin Cardiol 37:626-33. 2014
    ..However, the value of surgery in this patient subset has never been systematically studied...
  47. doi request reprint Comprehensive prognosis assessment by CMR imaging after ST-segment elevation myocardial infarction
    Ingo Eitel
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany Department of Cardiology, Angiology, Intensive Care Medicine, University of Lubeck, Medical Clinic II, Lubeck, Germany Electronic address
    J Am Coll Cardiol 64:1217-26. 2014
    ....
  48. doi request reprint Impact of long-term statin pretreatment on myocardial damage in ST elevation myocardial infarction (from the AIDA STEMI CMR Substudy)
    Georg Fuernau
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany Electronic address
    Am J Cardiol 114:503-9. 2014
    ..Furthermore, no differences in short- and long-term outcomes could be observed. In conclusion, in this CMR study, statin pretreatment in patients with STEMI was not associated with lesser myocardial damage. ..
  49. doi request reprint Growth-differentiation factor 15 and osteoprotegerin in acute myocardial infarction complicated by cardiogenic shock: a biomarker substudy of the IABP-SHOCK II-trial
    Georg Fuernau
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    Eur J Heart Fail 16:880-7. 2014
    ..OPG and GDF-15 may have additional prognostic impact on early prognosis assessment, being potentially useful for decision-making in CS...
  50. doi request reprint Reprint of "Intra-aortic balloon counterpulsation--basic principles and clinical evidence"
    Suzanne de Waha
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany Electronic address
    Vascul Pharmacol 61:30-4. 2014
    ..Current evidence, however, does not fully support routine use of IABP in these settings. This review focuses on the basic principles of IABP and discusses current evidence. ..
  51. doi request reprint Five-year clinical follow-up of a randomized comparison of a polymer-free sirolimus-eluting stent versus a polymer-based paclitaxel-eluting stent in patients with diabetes mellitus (LIPSIA Yukon trial)
    Thomas Stiermaier
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    Catheter Cardiovasc Interv 83:418-24. 2014
    ..At 9 months, the Yukon Choice stent failed to show non-inferiority in terms of the primary end point late lumen loss, while no significant difference in clinical outcome was detected...
  52. doi request reprint Endothelin-1 release in acute myocardial infarction as a predictor of long-term prognosis and no-reflow assessed by contrast-enhanced magnetic resonance imaging
    Ingo Eitel
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Germany
    Am Heart J 159:882-90. 2010
    ..The aim of our study was to assess the relationship between systemic ET-1 levels and the occurrence of no-reflow as well as to evaluate the prognostic value of ET-1 in a high-risk STEMI population...
  53. doi request reprint Long-term prognosis after extracorporeal life support in refractory cardiogenic shock: results from a real-world cohort
    Suzanne de Waha
    University Heart Centre Lübeck, University Hospital Schleswig Holstein, Medical Clinic II, Lubeck, Germany
    EuroIntervention 11:1363-71. 2016
    ....
  54. doi request reprint The challenges and impact of microvascular injury in ST-elevation myocardial infarction
    Sebastian Johannes Reinstadler
    a University Heart Center Lübeck, Medical Clinic II, Department of Cardiology, Angiology and Intensive Care Medicine, University of Lubeck, Lubeck, Germany
    Expert Rev Cardiovasc Ther 14:431-43. 2016
    ..This review provides an overview on the main pathophysiological mechanisms of MVI and its diagnostic approaches. Moreover, it will discuss its clinical consequences and current strategies of prevention and treatment. ..
  55. doi request reprint Intravenous morphine administration and reperfusion success in ST-elevation myocardial infarction: insights from cardiac magnetic resonance imaging
    Suzanne de Waha
    University Heart Centre, Medical Clinic II, Department of Cardiology Angiology Intensive Care Medicine, University of Schleswig Holstein, Campus Lubeck, Ratzeburger Allee 160, 23538, Lubeck, Germany
    Clin Res Cardiol 104:727-34. 2015
    ..Thus, we thought to analyse the impact of IV morphine on ischemic injury and salvaged myocardium assessed by cardiac magnetic resonance imaging (CMR) in patients with STEMI reperfused by primary coronary intervention (PCI)...
  56. doi request reprint Incidence, characteristics and functional implications of cerebral embolic lesions after the MitraClip procedure
    Stephan Blazek
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    EuroIntervention 10:1195-203. 2015
    ..This study aimed to assess the incidence and impact of cerebral embolic events after the MitraClip procedure...
  57. doi request reprint The potential additional diagnostic value of assessing for pericardial effusion on cardiac magnetic resonance imaging in patients with suspected myocarditis
    Philipp Lurz
    Department of Internal Medicine Cardiology, Heart Center of the University Leipzig, Struempellstr 39, 04289 Leipzig, Germany
    Eur Heart J Cardiovasc Imaging 15:643-50. 2014
    ..However, the incremental value of assessing for PE in addition to comprehensive cardiac magnetic resonance (CMR) imaging remains unclear...
  58. doi request reprint Intra-aortic balloon counterpulsation - basic principles and clinical evidence
    Suzanne de Waha
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany Electronic address
    Vascul Pharmacol 60:52-6. 2014
    ..Current evidence, however, does not fully support routine use of IABP in these settings. This review focuses on the basic principles of IABP and discusses current evidence. ..
  59. doi request reprint Association of upstream clopidogrel administration and myocardial reperfusion assessed by cardiac magnetic resonance imaging in patients with ST-elevation myocardial infarction
    Suzanne de Waha
    University of Leipzig, Leipzig, Germany
    Eur Heart J Acute Cardiovasc Care 3:110-7. 2014
    ..Aim of this study was to investigate the impact of upstream clopidogrel on infarct size and microvascular obstruction (MO) assessed by cardiac magnetic resonance imaging (CMR) in STEMI patients...
  60. doi request reprint Intracoronary compared with intravenous bolus abciximab application during primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: cardiac magnetic resonance substudy of the AIDA STEMI trial
    Ingo Eitel
    Heart Center, Department of Internal Medicine, Cardiology, University of Leipzig, Leipzig, Germany
    J Am Coll Cardiol 61:1447-54. 2013
    ....
  61. doi request reprint Aborted myocardial infarction in intracoronary compared with standard intravenous abciximab administration in patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction
    Ingo Eitel
    University of Leipzig, Heart Center, Department of Internal Medicine, Cardiology, Leipzig Germany
    Int J Cardiol 153:21-5. 2011
    ..So far the occurrence of aborted MI, a new therapeutic target of effective treatment in STEMI, has not been evaluated in IC versus IV abciximab administration in STEMI patients undergoing primary PCI...
  62. doi request reprint Intracoronary versus intravenous bolus abciximab during primary percutaneous coronary intervention in patients with acute ST-elevation myocardial infarction: a randomised trial
    Holger Thiele
    Universität Leipzig Heart Centre, Department of Internal Medicine Cardiology, Leipzig, Germany
    Lancet 379:923-31. 2012
    ..However, the safety and efficacy of intracoronary versus standard intravenous bolus application in patients with ST-elevation myocardial infarction (STEMI) undergoing this intervention has not been tested in a large-scale clinical trial...
  63. doi request reprint Prognostic significance and magnetic resonance imaging findings in aborted myocardial infarction after primary angioplasty
    Ingo Eitel
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Germany
    Am Heart J 158:806-13. 2009
    ..So far, the prognostic significance and magnetic resonance imaging (MRI) findings of an aborted MI after primary angioplasty have not been evaluated appropriately...
  64. doi request reprint Impairment of the endothelial glycocalyx in cardiogenic shock and its prognostic relevance
    Christian Jung
    Clinic of Internal Medicine I, Friedrich Schiller University, Jena, Germany Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany and Medical Clinic II, Cardiology Angiology Intensive Care Medicine, University Hospital Schleswig Holstein, University Heart Center Luebeck, Luebeck, Germany
    Shock 43:450-5. 2015
    ..003) together with serum lactate, age, and ejection fraction. Increased levels of S1 are an independent predictor of short-term mortality in patients with acute myocardial infarction and CS.ClinicalTrials.gov Identifier: NCT00491036. ..
  65. doi request reprint Frequency and significance of myocardial bridging and recurrent segment of the left anterior descending coronary artery in patients with takotsubo cardiomyopathy
    Thomas Stiermaier
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    Am J Cardiol 114:1204-9. 2014
    ..28). In conclusion, the prevalence of myocardial bridging in patients with TC is low and comparable with that in a matched control group. In contrast, LAD recurrent segments are significantly more frequent in patients with TC...
  66. doi request reprint Randomized comparison of percutaneous coronary intervention with sirolimus-eluting stents versus coronary artery bypass grafting in unprotected left main stem stenosis
    Enno Boudriot
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Germany
    J Am Coll Cardiol 57:538-45. 2011
    ..The purpose of this randomized study was to compare sirolimus-eluting stenting with coronary artery bypass grafting (CABG) for patients with unprotected left main (ULM) coronary artery disease...
  67. doi request reprint Intraaortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock: design and rationale of the Intraaortic Balloon Pump in Cardiogenic Shock II (IABP-SHOCK II) trial
    Holger Thiele
    University of Leipzig Heart Center, Leipzig, Germany
    Am Heart J 163:938-45. 2012
    ..The hypothesis of this trial is that IABP in addition to early revascularization by either percutaneous coronary intervention or coronary artery bypass grafting will improve clinical outcome of patients in cardiogenic shock...
  68. doi request reprint Clinical characteristics and cardiovascular magnetic resonance findings in stress (takotsubo) cardiomyopathy
    Ingo Eitel
    University of Leipzig Heart Center, Department of Internal Medicine Cardiology, Strumpellstrasse 39, 04289 Leipzig, Germany
    JAMA 306:277-86. 2011
    ..Various aspects of its clinical profile have been described in small single-center populations, but larger, multicenter data sets have been lacking so far. Furthermore, it remains difficult to quickly establish diagnosis on admission...
  69. pmc The relation between hypointense core, microvascular obstruction and intramyocardial haemorrhage in acute reperfused myocardial infarction assessed by cardiac magnetic resonance imaging
    Diana Kandler
    Department of Diagnostic and Interventional Radiology, University Leipzig Heart Centre, Strümpellstraße 39, 04289, Leipzig, Germany
    Eur Radiol 24:3277-88. 2014
    ..We aimed to distinguish between IMH and MVO by using T2 (*)-weighted cardiovascular magnetic resonance imaging (CMR) and analysed influencing factors for IMH development...
  70. doi request reprint Effect of carotid artery stenting on the release of S-100B and neurone-specific enolase
    Christiane Mattusch
    University of Leipzig Heart Center, Department of Internal Medicine Cardiology, Germany
    Angiology 62:376-80. 2011
    ..Neither patients with CAS nor those undergoing diagnostic angiography displayed any significant changes in serial NSE levels...
  71. doi request reprint Invasive versus non-invasive cooling after in- and out-of-hospital cardiac arrest: a randomized trial
    Undine Pittl
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Strümpellstr 39, 04289, Leipzig, Germany
    Clin Res Cardiol 102:607-14. 2013
    ..In this study, we compared the efficacy of two different cooling devices for temperature management in SCA survivors...