Peter Dechent

Summary

Country: Germany

Publications

  1. pmc Basal cerebral blood volume during the poststimulation undershoot in BOLD MRI of the human brain
    Peter Dechent
    MR Research in Neurology and Psychiatry, Georg August Universitat, Gottingen, Germany
    J Cereb Blood Flow Metab 31:82-9. 2011
  2. pmc Changed processing of visual sexual stimuli under GnRH-therapy--a single case study in pedophilia using eye tracking and fMRI
    Kirsten Jordan
    Department of Forensic Psychiatry and Psychotherapy, Georg August University Gottingen, Rosdorfer Weg 70, Göttingen 37081, Germany
    BMC Psychiatry 14:142. 2014
  3. pmc Normal response inhibition in boys with Tourette syndrome
    Veit Roessner
    Department of Child and Adolescent Psychiatry, University of Goettingen, Germany
    Behav Brain Funct 4:29. 2008
  4. ncbi request reprint Is the human primary motor cortex involved in motor imagery?
    Peter Dechent
    Biomedizinische NMR Forschungs GmbH am Max Planck Institut für biophysikalische Chemie, 37070 Gottingen, Germany
    Brain Res Cogn Brain Res 19:138-44. 2004
  5. ncbi request reprint Functional somatotopy of finger representations in human primary motor cortex
    Peter Dechent
    Biomedizinische NMR Forschungs GmbH am Max Planck Institut für biophysikalische Chemie, Gottingen, Germany
    Hum Brain Mapp 18:272-83. 2003
  6. ncbi request reprint Characterization of the human visual V6 complex by functional magnetic resonance imaging
    Peter Dechent
    Biomedizinische NMR Forschungs GmbH am Max Planck Institut für biophysikalische Chemie, 37070 Gottingen, Germany
    Eur J Neurosci 17:2201-11. 2003
  7. doi request reprint Neural correlates of fear of movement in high and low fear-avoidant chronic low back pain patients: an event-related fMRI study
    Antonia Barke
    Department of Clinical Psychology and Psychotherapy, University of Gottingen, Gottingen, Germany
    Pain 153:540-52. 2012
  8. doi request reprint High-resolution maps of magnetization transfer with inherent correction for RF inhomogeneity and T1 relaxation obtained from 3D FLASH MRI
    Gunther Helms
    MR Forschung in der Neurologie und Psychiatrie, Universitatsmedizin Gottingen, Gottingen, Germany
    Magn Reson Med 60:1396-407. 2008
  9. doi request reprint Transcranial direct current stimulation over the primary motor cortex during fMRI
    Andrea Antal
    Department of Clinical Neurophysiology, Georg August University of Gottingen, Gottingen, Germany
    Neuroimage 55:590-6. 2011
  10. doi request reprint Effects of spatial frequency and location of fearful faces on human amygdala activity
    Carmen Morawetz
    MR Research in Neurology and Psychiatry, Georg August University Goettingen, Goettingen, Germany
    Brain Res 1371:87-99. 2011

Detail Information

Publications47

  1. pmc Basal cerebral blood volume during the poststimulation undershoot in BOLD MRI of the human brain
    Peter Dechent
    MR Research in Neurology and Psychiatry, Georg August Universitat, Gottingen, Germany
    J Cereb Blood Flow Metab 31:82-9. 2011
    ..With the assumption of normalized cerebral blood flow after stimulus cessation, a normalized CBV lends support to the idea that the BOLD MRI undershoot reflects a prolonged elevation of oxidative metabolism...
  2. pmc Changed processing of visual sexual stimuli under GnRH-therapy--a single case study in pedophilia using eye tracking and fMRI
    Kirsten Jordan
    Department of Forensic Psychiatry and Psychotherapy, Georg August University Gottingen, Rosdorfer Weg 70, Göttingen 37081, Germany
    BMC Psychiatry 14:142. 2014
    ..Yet the therapeutic success of antiandrogens is uncertain especially regarding recidivism. Meta-analyses and reviews report only moderate and often mutually inconsistent effects...
  3. pmc Normal response inhibition in boys with Tourette syndrome
    Veit Roessner
    Department of Child and Adolescent Psychiatry, University of Goettingen, Germany
    Behav Brain Funct 4:29. 2008
    ..Inhibitory deficits are often a matter of debate in the pathophysiology of Tourette syndrome (TS). Previous neuropsychological studies on behavioral inhibition revealed equivocal results...
  4. ncbi request reprint Is the human primary motor cortex involved in motor imagery?
    Peter Dechent
    Biomedizinische NMR Forschungs GmbH am Max Planck Institut für biophysikalische Chemie, 37070 Gottingen, Germany
    Brain Res Cogn Brain Res 19:138-44. 2004
    ..This novel finding of a transient response reflecting the onset of imagination which does not lead to sustained M1 activation may explain previous contradictory reports...
  5. ncbi request reprint Functional somatotopy of finger representations in human primary motor cortex
    Peter Dechent
    Biomedizinische NMR Forschungs GmbH am Max Planck Institut für biophysikalische Chemie, Gottingen, Germany
    Hum Brain Mapp 18:272-83. 2003
    ..These results confirm previous concepts that finger somatotopy in the human M1 hand area emerges as a functional predominance of individual digit representations sharing common areas in a distributed though ordered network...
  6. ncbi request reprint Characterization of the human visual V6 complex by functional magnetic resonance imaging
    Peter Dechent
    Biomedizinische NMR Forschungs GmbH am Max Planck Institut für biophysikalische Chemie, 37070 Gottingen, Germany
    Eur J Neurosci 17:2201-11. 2003
    ..Further analyses of the functional coding of the human visual area V6 complex require functional magnetic resonance imaging at even higher spatial resolution...
  7. doi request reprint Neural correlates of fear of movement in high and low fear-avoidant chronic low back pain patients: an event-related fMRI study
    Antonia Barke
    Department of Clinical Psychology and Psychotherapy, University of Gottingen, Gottingen, Germany
    Pain 153:540-52. 2012
    ..Our findings do not support the fear component of the fear avoidance model...
  8. doi request reprint High-resolution maps of magnetization transfer with inherent correction for RF inhomogeneity and T1 relaxation obtained from 3D FLASH MRI
    Gunther Helms
    MR Forschung in der Neurologie und Psychiatrie, Universitatsmedizin Gottingen, Gottingen, Germany
    Magn Reson Med 60:1396-407. 2008
    ..It is inherently compensated for inhomogeneities of receive and transmit RF fields. The MT saturation appeared to be a sensitive parameter to depict MS lesions and alterations of normal-appearing white matter...
  9. doi request reprint Transcranial direct current stimulation over the primary motor cortex during fMRI
    Andrea Antal
    Department of Clinical Neurophysiology, Georg August University of Gottingen, Gottingen, Germany
    Neuroimage 55:590-6. 2011
    ..The MEP amplitude reflects changes in transsynaptic excitability of large pyramidal neurons while the BOLD signal is a measure of net synaptic activity of all cortical neurons...
  10. doi request reprint Effects of spatial frequency and location of fearful faces on human amygdala activity
    Carmen Morawetz
    MR Research in Neurology and Psychiatry, Georg August University Goettingen, Goettingen, Germany
    Brain Res 1371:87-99. 2011
    ..Our findings argue against the view that LSF information plays a crucial role in the processing of facial expressions in the amygdala and of a higher sensitivity to affective stimuli in the periphery...
  11. ncbi request reprint Split of attentional resources in human visual cortex
    Carmen Morawetz
    MR Research in Neurology and Psychiatry, Medical Faculty, Georg August University, Goettingen, Germany
    Vis Neurosci 24:817-26. 2007
    ..However, depending on the exact location and width of the attentional spotlights, resulting activation maps might reveal merged activation patterns even in the presence of distinct attentional spotlights...
  12. doi request reprint Differential activation of the middle-temporal complex to visual stimulation in migraineurs
    Andrea Antal
    Georg August University of Gottingen, Robert Koch Straße 40, Gottingen, Germany
    Cephalalgia 31:338-45. 2011
    ....
  13. doi request reprint Behavioral correlates of negative BOLD signal changes in the primary somatosensory cortex
    Andreas Kastrup
    Department of Neurology, University of Gottingen, Gottingen, Germany
    Neuroimage 41:1364-71. 2008
    ....
  14. doi request reprint The post-stimulation undershoot in BOLD fMRI of human brain is not caused by elevated cerebral blood volume
    Jens Frahm
    Biomedizinische NMR Forschungs GmbH am Max Planck Institut für biophysikalische Chemie, 37070 Gottingen, Germany
    Neuroimage 40:473-81. 2008
    ..7+/-7.2%). This finding renders a CBV contribution to the BOLD MRI undershoot unlikely and--in conjunction with a rapid post-stimulation return of CBF to baseline--supports the idea of a prolonged elevation of oxidative metabolism...
  15. pmc Reduced amygdalar and hippocampal size in adults with generalized social phobia
    Eva Irle
    Department of Psychiatry and Psychotherapy, University of Gottingen, Gottingen, Germany
    J Psychiatry Neurosci 35:126-31. 2010
    ..Structural and functional brain imaging studies suggest abnormalities of the amygdala and hippocampus in posttraumatic stress disorder and major depressive disorder. However, structural brain imaging studies in social phobia are lacking...
  16. pmc Identification of signal bias in the variable flip angle method by linear display of the algebraic Ernst equation
    Gunther Helms
    MR Research in Neurology and Psychiatry, University Medical Centre, Gottingen, Germany
    Magn Reson Med 66:669-77. 2011
    ..Signal bias, like due to slice-selective excitation or imperfect spoiling, can be readily identified by systematic deviations from the linear plot. The method is illustrated and validated by 3T experiments on phantoms and human brain...
  17. ncbi request reprint Magnetic resonance imaging and proton magnetic resonance spectroscopy of megalencephaly and dilated Virchow-Robin spaces
    Samuel Groeschel
    Department of Pediatrics and Neuropediatrics, Georg August Universitat, Gottingen, Germany
    Pediatr Neurol 34:35-40. 2006
    ..These data indicate that the dilatation of Virchow-Robin spaces reflects an underlying brain pathology causing neuroaxonal damage. Possible differential diagnoses are discussed...
  18. doi request reprint Pharmacokinetics of the MRI contrast agent gadobutrol in common marmoset monkeys (Callithrix jacchus)
    Gunther Helms
    Department of Cognitive Neurology, Göttingen University Medical Center, Gottingen, Germany
    J Med Primatol . 2016
    ..This study determined the pharmacokinetics of the contrast agent gadobutrol in marmosets by quantitative MRI to derive guidelines for neuroimaging protocols...
  19. doi request reprint Structural and quantitative neuroimaging of the common marmoset monkey using a clinical MRI system
    Gunther Helms
    Göttingen University Medical Center, Department of Cognitive Neurology, Gottingen, Germany
    J Neurosci Methods 215:121-31. 2013
    ..High-resolution MRI of common marmosets proved feasible using clinical MRI hardware. A rapid 3D examination protocol was established for screening under injection anesthesia, thus avoiding the adverse effects of inhalation anesthesia...
  20. doi request reprint Modeling the influence of TR and excitation flip angle on the magnetization transfer ratio (MTR) in human brain obtained from 3D spoiled gradient echo MRI
    Gunther Helms
    MR Research in Neurology and Psychiatry, University Medical Centre, Gottingen, Germany
    Magn Reson Med 64:177-85. 2010
    ..Optimal contrast is obtained around an MTR of 50%, and noise progression is reduced when a high reference signal is obtained...
  21. doi request reprint Increased SNR and reduced distortions by averaging multiple gradient echo signals in 3D FLASH imaging of the human brain at 3T
    Gunther Helms
    MR Research in Neurology and Psychiatry, Faculty of Medicine, Gottingen University, Gottingen, Germany
    J Magn Reson Imaging 29:198-204. 2009
    ..To demonstrate how averaging of multiple gradient echoes can improve high-resolution FLASH (fast low angle shot) magnetic resonance imaging (MRI) of the human brain...
  22. doi request reprint Untreated glioblastoma multiforme: increased myo-inositol and glutamine levels in the contralateral cerebral hemisphere at proton MR spectroscopy
    Kai Kallenberg
    MR Research in Neurology and Psychiatry, Department of Neuroradiology, Universitymedicine, Georg August Universitat Gottingen, Robert Koch Strasse 40, 37099 Gottingen, Germany
    Radiology 253:805-12. 2009
    ....
  23. doi request reprint Quantitative FLASH MRI at 3T using a rational approximation of the Ernst equation
    Gunther Helms
    MR Forschung in der Neurologie und Psychiatrie, Universitatsmedizin, Gottingen, Germany
    Magn Reson Med 59:667-72. 2008
    ..Local deviations from the nominal flip angles strongly affected the relaxation estimates and caused considerable blurring of the T1 histograms...
  24. doi request reprint Early reduction of total N-acetyl-aspartate-compounds in patients with classical vanishing white matter disease. A long-term follow-up MRS study
    Steffi F Dreha-Kulaczewski
    Department of Pediatrics and Pediatric Neurology, Georg August University, 37075 Gottingen, Germany
    Pediatr Res 63:444-9. 2008
    ..These early stages are followed by a complete cellular loss in cerebral WM...
  25. doi request reprint No advantage of time-of-flight magnetic resonance angiography at 3 Tesla compared to 1.5 Tesla in the follow-up after endovascular treatment of cerebral aneurysms
    Jan Hendrik Buhk
    Department of Neuroradiology, University of Gottingen, Robert Koch Str 40, 37075, Goettingen, Germany
    Neuroradiology 50:855-61. 2008
    ..Most centers perform one digital subtraction angiography (DSA) on follow-up continuing with time-of-flight magnetic resonance angiography (TOF-MRA). This study explores the diagnostic value of TOF-MRA at 1.5 T versus 3 T compared to DSA...
  26. pmc Serial proton MR spectroscopy and diffusion tensor imaging in infantile Balo's concentric sclerosis
    Steffi F Dreha-Kulaczewski
    Department of Pediatrics and Pediatric Neurology, Georg August University, Gottingen, Germany
    Neuroradiology 51:113-21. 2009
    ..The purpose was to elucidate biochemical and microstructural changes in Balo's concentric sclerosis lesions and to correlate the findings with the clinical course...
  27. pmc Diverting attention suppresses human amygdala responses to faces
    Carmen Morawetz
    MR Research in Neurology and Psychiatry, Georg August University Goettingen Goettingen, Germany
    Front Hum Neurosci 4:226. 2010
    ....
  28. doi request reprint Increased putamen and callosal motor subregion in treatment-naïve boys with Tourette syndrome indicates changes in the bihemispheric motor network
    Veit Roessner
    Department of Child and Adolescent Psychiatry, University Medical Centre, Dresden, Germany
    J Child Psychol Psychiatry 52:306-14. 2011
    ..In the present study, these confounders were excluded to identify differences in basal ganglia and corpus callosum size that can be ascribed more probably to Tourette syndrome per se...
  29. pmc Brain Metabolite Changes in Patients with Relapsing-Remitting and Secondary Progressive Multiple Sclerosis: A Two-Year Follow-Up Study
    Dorothea Obert
    Department of Neurology, University Medical Center Gottingen, Gottingen, Germany
    PLoS ONE 11:e0162583. 2016
    ..Analyzing correlations between MRS metabolites in the NAWM and patients clinical status we found the positive correlation of Ins/tNAA with disability in patients with RRMS. In SPMS positive correlation of Cho with disability was found. ..
  30. pmc Neurocognitive functions and brain atrophy after proven neuroborreliosis: a case-control study
    Holger Schmidt
    University Medical Centre Göttingen, Department of Neurology, Robert Koch Str 40, Gottingen, 37075, Germany
    BMC Neurol 15:139. 2015
    ..Patients often report neurocognitive difficulties after neuroborreliosis (NB). The frequency and extent of cognitive problems in European patients have been studied incompletely...
  31. doi request reprint Assessment of myelination in hypomyelinating disorders by quantitative MRI
    Steffi F Dreha-Kulaczewski
    Department of Pediatrics and Pediatric Neurology, University Medical Center Gottingen, Germany Department of Cognitive Neurology, MR Research in Neurology and Psychiatry, University Medical Center Gottingen, Germany
    J Magn Reson Imaging 36:spcone. 2012
    ..To apply myelin-sensitive quantitative magnetic resonance imaging (MRI) techniques in defined hypomyelinating conditions and to identify spatial patterns of myelination as criteria for characterization of undefined disorders...
  32. doi request reprint Assessment of myelination in hypomyelinating disorders by quantitative MRI
    Steffi F Dreha-Kulaczewski
    Department of Pediatrics and Pediatric Neurology, University Medical Center Gottingen, Germany
    J Magn Reson Imaging 36:1329-38. 2012
    ..To apply myelin-sensitive quantitative magnetic resonance imaging (MRI) techniques in defined hypomyelinating conditions and to identify spatial patterns of myelination as criteria for characterization of undefined disorders...
  33. pmc Folate receptor alpha defect causes cerebral folate transport deficiency: a treatable neurodegenerative disorder associated with disturbed myelin metabolism
    Robert Steinfeld
    Department of Pediatrics and Pediatric Neurology, Georg August University Gottingen, Gottingen, Germany
    Am J Hum Genet 85:354-63. 2009
    ..Our studies not only characterize a previously unknown and treatable disorder of early childhood, but also provide new insights into the folate metabolic pathways involved in postnatal myelination and brain development...
  34. ncbi request reprint Contrast-driven approach to intracranial segmentation using a combination of T2- and T1-weighted 3D MRI data sets
    Gunther Helms
    MR Forschung, Bereich Humanmedizin, Universitat Gottingen, Gottingen, Germany
    J Magn Reson Imaging 24:790-5. 2006
    ..To develop a strategy for structural brain imaging when using FSL software for segmentation and subsequent volumetry...
  35. doi request reprint Individual voxel-based subtype prediction can differentiate progressive supranuclear palsy from idiopathic Parkinson syndrome and healthy controls
    Niels K Focke
    Department of Clinical Neurophysiology, Georg August University, Gottingen, Germany
    Hum Brain Mapp 32:1905-15. 2011
    ..In summary, a voxel-based SVM analysis allows for a reliable classification of individual cases in PSP that can be directly clinically useful. For patients with MSA and IPS, further developments like quantitative MRI are needed...
  36. doi request reprint Optimized high-resolution mapping of magnetization transfer (MT) at 3 Tesla for direct visualization of substructures of the human thalamus in clinically feasible measurement time
    Tabea Gringel
    MR Forschung in der Neurologie und Psychiatrie, Universitatsmedizin, MRT4, TL190, Gottingen, Germany
    J Magn Reson Imaging 29:1285-92. 2009
    ..To optimize contrast-to-noise and spatial resolution of a FLASH-based magnetization transfer (MT) protocol for visualization of substructures in human thalamus...
  37. ncbi request reprint Improved functional mapping of the human amygdala using a standard functional magnetic resonance imaging sequence with simple modifications
    Carmen Morawetz
    MR Research in Neurology and Psychiatry, Medical Faculty, Georg August University Gottingen, 37099 Gottingen, Germany
    Magn Reson Imaging 26:45-53. 2008
    ..e., the reduction of section thickness) is sufficient to improve the detectability of amygdala activation...
  38. pmc Rapid radiofrequency field mapping in vivo using single-shot STEAM MRI
    Gunther Helms
    Faculty of Medicine, MR Research in Neurology and Psychiatry, University of Gottingen, Gottingen, Germany
    Magn Reson Med 60:739-43. 2008
    ..Flip angles between 75% and 125% of the nominal value were measured in line with other methods...
  39. doi request reprint Cortical sensorimotor control in vocalization: a functional magnetic resonance imaging study
    Arno Olthoff
    Department of Phoniatrics and Pedaudiology, University of Gottingen, Gottingen, Germany
    Laryngoscope 118:2091-6. 2008
    ..Verbal communication is a human feature and volitional vocalization is its basis. However, little is known regarding the cortical areas involved in human vocalization...
  40. doi request reprint Image-guided intracranial endosonography
    Naureen Keric
    Department of Neurosurgery, Georg August University of Gottingen, Gottingen, Germany
    J Neurosurg Anesthesiol 25:317-23. 2013
    ..The present study was designed to investigate the suitability of an image-guided intracranial endosonography (IGIE) catheter for intracranial ultrasound imaging in an ex vivo phantom model and in a large animal model...
  41. ncbi request reprint Succinate in dystrophic white matter: a proton magnetic resonance spectroscopy finding characteristic for complex II deficiency
    Knut Brockmann
    Department of Pediatrics and Neuropediatrics, Children s Hospital, University of Gottingen, Gottingen, Germany
    Ann Neurol 52:38-46. 2002
    ..Magnetic resonance spectroscopy provides a characteristic pattern in succinate dehydrogenase deficiency...
  42. ncbi request reprint Cerebral proton magnetic resonance spectroscopy of a patient with giant axonal neuropathy
    Knut Brockmann
    Department of Pediatrics and Neuropediatrics, Georg August Universitat, Children s Hospital, Robert Koch Strasse 40, 37075 Goettingen, Germany
    Brain Dev 25:45-50. 2003
    ....
  43. ncbi request reprint The neural basis of the egocentric and allocentric spatial frame of reference
    Tino Zaehle
    Department of Psychology, Division Neuropsychology, University of Zurich, Binzmuhlestrasse 14, CH 8050 Zurich, Switzerland
    Brain Res 1137:92-103. 2007
    ..These data suggest that a hierarchically organized processing system exists in which the egocentric spatial coding requires only a subsystem of the processing resources of the allocentric condition...
  44. ncbi request reprint Quantitative proton MRS of cerebral metabolites in laminin alpha2 chain deficiency
    Knut Brockmann
    Department of Paediatrics and Paediatric Neurology, Georg August University, 37075 Gottingen, Germany
    Brain Dev 29:357-64. 2007
    ..This interpretation is in line with the hypothesis that laminin alpha2 deficiency results in leakage of fluids across the blood-brain barrier and a histopathological report of astrocytic proliferation in CMD...
  45. ncbi request reprint Cerebral proton magnetic resonance spectroscopy in infantile Alexander disease
    Knut Brockmann
    Dept of Paediatrics and Neuropaediatrics, Children s Hospital, Robert Koch Str 40, 37075 Gottingen, Germany
    J Neurol 250:300-6. 2003
    ..The accumulation of lactate in affected white matter is in line with infiltrating macrophages. Metabolic alterations demonstrated by in vivo proton MRS are in excellent agreement with known neuropathological features of AD...
  46. ncbi request reprint Imaging the brain activity changes underlying impaired visuospatial judgments: simultaneous FMRI, TMS, and behavioral studies
    Alexander T Sack
    Department of Cognitive Neuroscience, Faculty of Psychology, Maastricht University, 6200 MD Maastricht, The Netherlands
    Cereb Cortex 17:2841-52. 2007
    ....
  47. ncbi request reprint Cerebral metabolic and structural alterations in hereditary spastic paraplegia with thin corpus callosum assessed by MRS and DTI
    Steffi Dreha-Kulaczewski
    Department of Pediatrics and Pediatric Neurology, Faculty of Medicine, Georg August University, Robert Koch Str 40, 37075 Gottingen, Germany
    Neuroradiology 48:893-8. 2006
    ..Characteristic clinical features comprise progressive spastic gait, cognitive impairment, and ataxia. Diagnostic MRI findings include thinning of the corpus callosum and non-progressive white matter (WM) alterations...