Traute Demirakca

Summary

Affiliation: Central Institute of Mental Health
Country: Germany

Publications

  1. doi request reprint Effects of alcoholism and continued abstinence on brain volumes in both genders
    Traute Demirakca
    Department of Neuroimaging, Central Institute of Mental Health, Mannheim, Germany
    Alcohol Clin Exp Res 35:1678-85. 2011
  2. doi request reprint Loss of control of alcohol use and severity of alcohol dependence in non-treatment-seeking heavy drinkers are related to lower glutamate in frontal white matter
    Gabriele Ende
    Department Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
    Alcohol Clin Exp Res 37:1643-9. 2013
  3. ncbi request reprint Alcohol consumption significantly influences the MR signal of frontal choline-containing compounds
    Gabriele Ende
    Department of Neuroimaging and Department of Addictive Behaviour and Addiction Medicine, Central Institute of Mental Health, PO Box 12 21 20, D 68072 Mannheim, Germany
    Neuroimage 32:740-6. 2006
  4. doi request reprint Does body shaping influence brain shape? Habitual physical activity is linked to brain morphology independent of age
    Traute Demirakca
    Department of Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim University of Heidelberg, Mannheim, Germany
    World J Biol Psychiatry 15:387-96. 2014
  5. doi request reprint Women with borderline personality disorder do not show altered BOLD responses during response inhibition
    Julia van Eijk
    Department of Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim Heidelberg University, Germany
    Psychiatry Res 234:378-89. 2015
  6. doi request reprint (31) P RINEPT MRSI and VBM reveal alterations in brain aging associated with major depression
    Sarah V Biedermann
    Department Neuroimaging, Central Institute of Mental Health Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
    Magn Reson Med 73:spcone. 2015
  7. doi request reprint Effects of normal aging and SCN1A risk-gene expression on brain metabolites: evidence for an association between SCN1A and myo-inositol
    Nuran Tunc-Skarka
    Department of Neuroimaging, Central Institute of Mental Health, Medical Faculty of Mannheim Heidelberg University, Germany
    NMR Biomed 27:228-34. 2014
  8. ncbi request reprint Subcortical and medial temporal MR-detectable metabolite abnormalities in unipolar major depression
    Gabriele Ende
    Division Neuroimaging, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
    Eur Arch Psychiatry Clin Neurosci 257:36-9. 2007
  9. doi request reprint Longitudinal Mapping of Gyral and Sulcal Patterns of Cortical Thickness and Brain Volume Regain during Early Alcohol Abstinence
    Guo Ying Wang
    Department of Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim Heidelberg University, Mannheim, Germany
    Eur Addict Res 22:80-9. 2016
  10. doi request reprint Impulsivity and Aggression in Female BPD and ADHD Patients: Association with ACC Glutamate and GABA Concentrations
    Gabriele Ende
    Department of Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim Heidelberg University, Mannheim, Germany
    Neuropsychopharmacology 41:410-8. 2016

Detail Information

Publications23

  1. doi request reprint Effects of alcoholism and continued abstinence on brain volumes in both genders
    Traute Demirakca
    Department of Neuroimaging, Central Institute of Mental Health, Mannheim, Germany
    Alcohol Clin Exp Res 35:1678-85. 2011
    ....
  2. doi request reprint Loss of control of alcohol use and severity of alcohol dependence in non-treatment-seeking heavy drinkers are related to lower glutamate in frontal white matter
    Gabriele Ende
    Department Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
    Alcohol Clin Exp Res 37:1643-9. 2013
    ..This study investigated magnetic resonance spectroscopy (MRS)-detectable Glu levels in frontal WM of non-treatment-seeking heavy drinkers and its associations with AUD symptoms...
  3. ncbi request reprint Alcohol consumption significantly influences the MR signal of frontal choline-containing compounds
    Gabriele Ende
    Department of Neuroimaging and Department of Addictive Behaviour and Addiction Medicine, Central Institute of Mental Health, PO Box 12 21 20, D 68072 Mannheim, Germany
    Neuroimage 32:740-6. 2006
    ....
  4. doi request reprint Does body shaping influence brain shape? Habitual physical activity is linked to brain morphology independent of age
    Traute Demirakca
    Department of Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim University of Heidelberg, Mannheim, Germany
    World J Biol Psychiatry 15:387-96. 2014
    ..However, the impact of PA on brain morphology was mainly demonstrated in seniors. We investigated healthy individuals across a broad age range for the relation between habitual PA and brain morphology...
  5. doi request reprint Women with borderline personality disorder do not show altered BOLD responses during response inhibition
    Julia van Eijk
    Department of Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim Heidelberg University, Germany
    Psychiatry Res 234:378-89. 2015
    ..Our results provide evidence that under emotionally neutral conditions response inhibition is not impaired in patients with BPD without co-occurring ADHD. ..
  6. doi request reprint (31) P RINEPT MRSI and VBM reveal alterations in brain aging associated with major depression
    Sarah V Biedermann
    Department Neuroimaging, Central Institute of Mental Health Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
    Magn Reson Med 73:spcone. 2015
    ..Thus, combining MR phosphorous spectroscopy and volumetry in depressed patients seems to be a promising approach to detect underlying pathomechanisms...
  7. doi request reprint Effects of normal aging and SCN1A risk-gene expression on brain metabolites: evidence for an association between SCN1A and myo-inositol
    Nuran Tunc-Skarka
    Department of Neuroimaging, Central Institute of Mental Health, Medical Faculty of Mannheim Heidelberg University, Germany
    NMR Biomed 27:228-34. 2014
    ..Our results corroborated the age-related changes in metabolite concentrations, and found evidence for a link between SCN1A and frontal white matter mI in healthy subjects...
  8. ncbi request reprint Subcortical and medial temporal MR-detectable metabolite abnormalities in unipolar major depression
    Gabriele Ende
    Division Neuroimaging, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
    Eur Arch Psychiatry Clin Neurosci 257:36-9. 2007
    ..Abnormal levels of choline-containing compounds most likely reflect altered membrane phospholipid metabolism. A reduced level in the hippocampus and an increased level in the putamen suggest regionally opponent membrane abnormalities...
  9. doi request reprint Longitudinal Mapping of Gyral and Sulcal Patterns of Cortical Thickness and Brain Volume Regain during Early Alcohol Abstinence
    Guo Ying Wang
    Department of Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim Heidelberg University, Mannheim, Germany
    Eur Addict Res 22:80-9. 2016
    ..During the initial 2 weeks of abstinence no subcortical volume regain was observed. Either the time span was too short or the lower subcortical volume could represent a predisposing trait marker...
  10. doi request reprint Impulsivity and Aggression in Female BPD and ADHD Patients: Association with ACC Glutamate and GABA Concentrations
    Gabriele Ende
    Department of Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim Heidelberg University, Mannheim, Germany
    Neuropsychopharmacology 41:410-8. 2016
    ..If distinct associations of Glu/tCr and GABA for BPD and ADHD can be confirmed in future studies, this might yield implications for more specific pharmacological treatments. ..
  11. doi request reprint Diminished gray matter in the hippocampus of cannabis users: possible protective effects of cannabidiol
    Traute Demirakca
    Department of Neuroimaging, Central Institute of Mental Health, Mannheim, Germany
    Drug Alcohol Depend 114:242-5. 2011
    ..Chronic cannabis use has been associated with memory deficits and a volume reduction of the hippocampus, but none of the studies accounted for different effects of tetrahydrocannabinol (THC) and cannabidiol (CBD)...
  12. doi request reprint Abnormal amygdala activation profile in pedophilia
    Alexander Sartorius
    Central Institute of Mental Health, J5, 68159, Mannheim, Germany
    Eur Arch Psychiatry Clin Neurosci 258:271-7. 2008
    ..More extensive research in this field would be of benefit for both the victims and the offenders...
  13. doi request reprint 31P RINEPT MRSI and VBM reveal alterations in brain aging associated with major depression
    Sarah V Biedermann
    Department Neuroimaging, Central Institute of Mental Health Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
    Magn Reson Med 73:1390-400. 2015
    ..Thus, combining MR phosphorous spectroscopy and volumetry in depressed patients seems to be a promising approach to detect underlying pathomechanisms...
  14. doi request reprint Rapid partial regeneration of brain volume during the first 14 days of abstinence from alcohol
    Julia van Eijk
    Department of Neuroimaging, Central Institute for Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
    Alcohol Clin Exp Res 37:67-74. 2013
    ..The aim of this study was to investigate whether volumetric amelioration takes place already within the first 2 weeks of abstinence...
  15. ncbi request reprint The biochemistry of dysfunctional emotions: proton MR spectroscopic findings in major depressive disorder
    Gabriele Ende
    NMR Research in Psychiatry, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
    Prog Brain Res 156:481-501. 2006
    ..This review summarizes the literature about biochemical changes quantified via 1H MRS in MDD patients in brain regions that play an important role for the communication and processing of emotions...
  16. ncbi request reprint Disturbance in the neural circuitry underlying positive emotional processing in post-traumatic stress disorder (PTSD). An fMRI study
    Alexander Jatzko
    Central Institute of Mental Health ZI NMR Research, 122120, 68072, Mannheim, Germany
    Eur Arch Psychiatry Clin Neurosci 256:112-4. 2006
    ..This pilot study is the first to reveal alterations in the processing of positive emotions in PTSD possibly reflecting a neuronal correlate of the symptom of emotional numbness in PTSD...
  17. doi request reprint SCN1A affects brain structure and the neural activity of the aging brain
    Sandra Meier
    Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Heidelberg, Germany
    Biol Psychiatry 72:677-83. 2012
    ..rs10930201 was further observed to be related to differences in neural activity during a working memory task...
  18. doi request reprint In vivo voxel based morphometry: detection of increased hippocampal volume and decreased glutamate levels in exercising mice
    Sarah Biedermann
    Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim University of Heidelberg, Mannheim, Germany
    Neuroimage 61:1206-12. 2012
    ..An inverse correlation of hippocampal gray matter volume and glutamate concentration indicates a possible implication of the glutamatergic system for hippocampal volume...
  19. ncbi request reprint Differential effects of long-term treatment with clozapine or haloperidol on GABAA receptor binding and GAD67 expression
    Mathias Zink
    Central Institute of Mental Health, P O Box 12 21 20, D 68072 Mannheim, Germany
    Schizophr Res 66:151-7. 2004
    ..However, the reduced GAD67 expression seen in postmortem brains does not appear to reflect drug effects, since our animal model demonstrated increased gene expression...
  20. doi request reprint Electroconvulsive therapy increases temporal gray matter volume and cortical thickness
    Alexander Sartorius
    Research Group Translational Imaging, Department of Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany Electronic address
    Eur Neuropsychopharmacol 26:506-17. 2016
    ..Our data widely exclude white matter loss as an indirect cause of GM growth. Our data add further evidence to the hypothesis that ECT enables plasticity falsifying older ideas of ECT induced "brain damaging". ..
  21. pmc The Exercising Brain: Changes in Functional Connectivity Induced by an Integrated Multimodal Cognitive and Whole-Body Coordination Training
    Traute Demirakca
    Department of Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, J5, 68159 Mannheim, Germany
    Neural Plast 2016:8240894. 2016
    ....
  22. pmc Voxel-based morphometry in women with borderline personality disorder with and without comorbid posttraumatic stress disorder
    Inga Niedtfeld
    Department of Psychosomatic Medicine, Central Institute of Mental Health Mannheim, Medical Faculty Mannheim Heidelberg University, Mannheim, Germany
    PLoS ONE 8:e65824. 2013
    ..We could replicate earlier findings of diminished limbic GMV in patients with BPD and additionally show that patients with co-morbid PTSD feature increased GMV in prefrontal regions associated with cognitive control...
  23. ncbi request reprint Functioning and neuronal viability of the anterior cingulate neurons following antipsychotic treatment: MR-spectroscopic imaging in chronic schizophrenia
    Dieter F Braus
    NMR Research and Clinic for Psychiatry and Psychotherapy, Central Institute of Mental Health, J5, D 68159 Mannheim, Germany
    Eur Neuropsychopharmacol 12:145-52. 2002
    ..These results suggest that atypical antipsychotics modify the function of anterior cingulate neurons in a specific manner...