Albrecht Bufe

Summary

Country: Germany

Publications

  1. pmc EAACI: A European Declaration on Immunotherapy. Designing the future of allergen specific immunotherapy
    Moises A Calderon
    Section of Allergy and Clinical Immunology, Imperial College, National Heart and Lung Institute, Dovehouse Street, London, SW3 6LY, UK
    Clin Transl Allergy 2:20. 2012
  2. pmc Relevance of human metapneumovirus in exacerbations of COPD
    G Rohde
    Department of Internal Medicine III, Pneumology, Allergology and Sleep Medicine, University Hospital Bergmannsheil, D 44789 Bochum, Germany
    Respir Res 6:150. 2005
  3. pmc Evaluation of the toll-like receptor 6 Ser249Pro polymorphism in patients with asthma, atopic dermatitis and chronic obstructive pulmonary disease
    Sabine Hoffjan
    Department of Human Genetics, Ruhr University Bochum, Germany
    BMC Med Genet 6:34. 2005
  4. doi request reprint Specific immunotherapy in children
    A Bufe
    Department of Experimental Pneumology, Ruhr University Bochum, Bochum, Germany
    Clin Exp Allergy 41:1256-62. 2011
  5. doi request reprint Safety and efficacy in children of an SQ-standardized grass allergen tablet for sublingual immunotherapy
    Albrecht Bufe
    Experimental Pneumonology, Ruhr University Bochum, Bergmannsheil University Clinics, Bochum, Germany
    J Allergy Clin Immunol 123:167-173.e7. 2009
  6. doi request reprint Arabinogalactan isolated from cowshed dust extract protects mice from allergic airway inflammation and sensitization
    Marcus Peters
    Department of Experimental Pneumology, Ruhr University Bochum, Bochum, Germany
    J Allergy Clin Immunol 126:648-56.e1-4. 2010
  7. doi request reprint Proteolytic activity in cowshed dust extracts induces C5a release in murine bronchoalveolar lavage fluids which may account for its protective properties in allergic airway inflammation
    Matthias Stiehm
    Department of Experimental Pneumology, Ruhr University Bochum, Bochum, Germany
    Thorax 68:31-8. 2013
  8. doi request reprint T-cell polarization depends on concentration of the danger signal used to activate dendritic cells
    Marcus Peters
    Department of Experimental Pneumology, Ruhr University Bochum, Bochum, Germany
    Immunol Cell Biol 88:537-44. 2010
  9. ncbi request reprint Synergistically upregulated interleukin-10 production in cocultures of monocytes and T cells after stimulation with respiratory syncytial virus
    Marion Kauth
    Department of Experimental Pneumology, Ruhr University Bochum, Bochum, Germany
    Int Arch Allergy Immunol 142:116-26. 2007
  10. ncbi request reprint Lysine as a critical amino acid for IgE binding in Phl p 5b C terminus
    Kirsten Gehlhar
    Department of Experimental Pneumology, Ruhr University Bochum, Bochum, Germany
    Int Arch Allergy Immunol 140:285-94. 2006

Collaborators

Detail Information

Publications21

  1. pmc EAACI: A European Declaration on Immunotherapy. Designing the future of allergen specific immunotherapy
    Moises A Calderon
    Section of Allergy and Clinical Immunology, Imperial College, National Heart and Lung Institute, Dovehouse Street, London, SW3 6LY, UK
    Clin Transl Allergy 2:20. 2012
    ....
  2. pmc Relevance of human metapneumovirus in exacerbations of COPD
    G Rohde
    Department of Internal Medicine III, Pneumology, Allergology and Sleep Medicine, University Hospital Bergmannsheil, D 44789 Bochum, Germany
    Respir Res 6:150. 2005
    ....
  3. pmc Evaluation of the toll-like receptor 6 Ser249Pro polymorphism in patients with asthma, atopic dermatitis and chronic obstructive pulmonary disease
    Sabine Hoffjan
    Department of Human Genetics, Ruhr University Bochum, Germany
    BMC Med Genet 6:34. 2005
    ..We evaluated here the role of a coding variation, Ser249Pro, in the TLR6 gene in the pathogenesis of asthma, atopic dermatitis (AD) and chronic obstructive pulmonary disease (COPD)...
  4. doi request reprint Specific immunotherapy in children
    A Bufe
    Department of Experimental Pneumology, Ruhr University Bochum, Bochum, Germany
    Clin Exp Allergy 41:1256-62. 2011
    ..In these patients, symptoms and use of anti-inflammatory therapy can be reduced by SIT...
  5. doi request reprint Safety and efficacy in children of an SQ-standardized grass allergen tablet for sublingual immunotherapy
    Albrecht Bufe
    Experimental Pneumonology, Ruhr University Bochum, Bergmannsheil University Clinics, Bochum, Germany
    J Allergy Clin Immunol 123:167-173.e7. 2009
    ..Allergic asthma and rhinoconjunctivitis are closely linked, and a strategy combining treatment of the upper and lower airways is recommended...
  6. doi request reprint Arabinogalactan isolated from cowshed dust extract protects mice from allergic airway inflammation and sensitization
    Marcus Peters
    Department of Experimental Pneumology, Ruhr University Bochum, Bochum, Germany
    J Allergy Clin Immunol 126:648-56.e1-4. 2010
    ..Extract from cowshed dust (CDE) is a source of immunomodulating substances. We have previously shown that such substances protect from experimental allergic disorders in a mouse model of asthma...
  7. doi request reprint Proteolytic activity in cowshed dust extracts induces C5a release in murine bronchoalveolar lavage fluids which may account for its protective properties in allergic airway inflammation
    Matthias Stiehm
    Department of Experimental Pneumology, Ruhr University Bochum, Bochum, Germany
    Thorax 68:31-8. 2013
    ..Thus we investigated whether CDE can activate the complement system to release biologically active C5a in the lung...
  8. doi request reprint T-cell polarization depends on concentration of the danger signal used to activate dendritic cells
    Marcus Peters
    Department of Experimental Pneumology, Ruhr University Bochum, Bochum, Germany
    Immunol Cell Biol 88:537-44. 2010
    ..Further activation of BMDCs is required to prime mice for allergic immune response. In this study, we show that LPS is a suitable stimulus. However, when cells were activated with high dose LPS they tended to induce a Th17 response...
  9. ncbi request reprint Synergistically upregulated interleukin-10 production in cocultures of monocytes and T cells after stimulation with respiratory syncytial virus
    Marion Kauth
    Department of Experimental Pneumology, Ruhr University Bochum, Bochum, Germany
    Int Arch Allergy Immunol 142:116-26. 2007
    ..Here, we investigated the potential direct interaction between RSV and T cells and its impact on cytokine response...
  10. ncbi request reprint Lysine as a critical amino acid for IgE binding in Phl p 5b C terminus
    Kirsten Gehlhar
    Department of Experimental Pneumology, Ruhr University Bochum, Bochum, Germany
    Int Arch Allergy Immunol 140:285-94. 2006
    ..Nevertheless, these studies are hampered by limited significance due to the often conformational nature of IgE epitopes. This prompted us to study the role of lysines in the context of an intact 3-dimensional model...
  11. doi request reprint Stepwise isolation of human peripheral erythrocytes, T lymphocytes, and monocytes for blood cell proteomics
    Frederic Brosseron
    Abteilung für Funktionelle Proteomik, Medizinisches Proteom Center, Ruhr University Bochum, Bochum, Germany
    Proteomics Clin Appl 6:497-501. 2012
    ..In this article, we give detailed description of a stepwise application of these methods as one isolation strategy for enrichment of different cell types from one blood sample...
  12. ncbi request reprint A bioassay for determination of lipopolysaccharide in environmental samples
    Marcus Peters
    Department of Experimental Pneumology, Ruhr University Bochum, Bochum, Germany
    Innate Immun 18:694-9. 2012
    ....
  13. doi request reprint Comparison of metabolites in exhaled breath and bronchoalveolar lavage fluid samples in a mouse model of asthma
    Stephanie Neuhaus
    Department of Experimental Pneumology, Ruhr University Bochum, Bochum, Germany
    J Appl Physiol (1985) 111:1088-95. 2011
    ..The possibility of measuring the exhaled breath of mice was evaluated previously. The aim of the present study was to reveal whether mice affected by airway inflammation can be identified via MCC/IMS...
  14. doi request reprint Anti-inflammatory modulation of immune response by probiotic Escherichia coli Nissle 1917 in human blood mononuclear cells
    Anne Katrin Güttsches
    Department of Experimental Pneumology, Ruhr University Bochum, Germany
    Innate Immun 18:204-16. 2012
    ..Both effects may contribute to the probiotic properties of EcN...
  15. doi request reprint Modulation of dendritic cell function by cowshed dust extract
    Leonid Gorelik
    Department of Experimental Pneumology, Ruhr University Bochum, Bochum, Germany
    Innate Immun 14:345-55. 2008
    ..Furthermore, we present evidence that an autocrine IL-10 dependent mechanism seems to be involved in down-regulation of dendritic cell function due to stimulation with CDE...
  16. ncbi request reprint Anti-BDCA-4 (neuropilin-1) antibody can suppress virus-induced IFN-alpha production of plasmacytoid dendritic cells
    Evelin Grage-Griebenow
    Experimental Pneumology, Ruhr University Bochum, Bochum, Germany
    Immunol Cell Biol 85:383-90. 2007
    ..In conclusion, data suggest an immunoregulatory role for BDCA-4 on PDC as demonstrated for IFN-alpha response to virus...
  17. doi request reprint Influence of an Allergen-Specific Th17 Response on Remodeling of the Airways
    Marcus Peters
    Department of Experimental Pneumology, Ruhr University Bochum, Bochum, Germany
    Am J Respir Cell Mol Biol 54:350-8. 2016
    ..Furthermore, we revealed that increased remodeling is not only based on neutrophilic inflammation, but also on the direct impact of IL-17A on airway structural cells. ..
  18. doi request reprint Allergy-Protective Arabinogalactan Modulates Human Dendritic Cells via C-Type Lectins and Inhibition of NF-κB
    Marcus Peters
    Department of Experimental Pneumology, Ruhr University Bochum, 44801 Bochum, Germany
    J Immunol 196:1626-35. 2016
    ..We conclude that AG dampens the activation of human DCs by LPS via binding to DC-SIGN and MMR-1, leading to attenuated TLR signaling. This results in a reduced T cell activation capacity of DCs. ..
  19. doi request reprint Viral colonization in intubated patients: initial pathogen pattern and follow-up
    Barbara Monika Hauptmeier
    Medical Clinic III, University Hospital Bergmannsheil, Bochum, Germany
    Clin Respir J 4:139-46. 2010
    ..Colonization of the lower respiratory tract is an independent risk factor for ventilator-associated pneumonia. Little is known about the frequency of viral colonization on intubation and during mechanical ventilation...
  20. ncbi request reprint Characterization of modified allergen extracts by in vitro beta-hexosaminidase release from rat basophils
    Kirsten Gehlhar
    Experimental Pneumology, Ruhr University Bochum, Bochum, Germany
    Int Arch Allergy Immunol 136:311-9. 2005
    ....
  21. ncbi request reprint Atopic phenotype in children is associated with decreased virus-induced interferon-alpha release
    Albrecht Bufe
    Department of Experimental Pneumology, Ruhr University Bochum, Bochum, Germany
    Int Arch Allergy Immunol 127:82-8. 2002
    ..Little is known about the role of IFN-alpha in allergic disease...