- Oxymetazoline inhibits and resolves inflammatory reactions in human neutrophilsIngrid Beck-Speier
Helmholtz Center Munich, German Research Center for Environmental Health, Institute of Lung Biology and Disease, Germany
J Pharmacol Sci 110:276-84. 2009..Since LXA(4) is most relevant in returning inflamed tissue to homeostasis, OMZ is postulated to terminate rhinitis-related inflammation, thus contributing to shortening of disease duration...
- Ultrafine particles affect the balance of endogenous pro- and anti-inflammatory lipid mediators in the lung: in-vitro and in-vivo studiesIngrid Beck-Speier
Institute of Allergy Research, Helmholtz Zentrum Technische Universität München, Helmholtz Zentrum Munchen, German
Part Fibre Toxicol 9:27. 2012..Lipid mediators, known to be immediately generated in response to tissue injury, might be strong candidates for priming this particle-triggered change of the inflammatory balance...
- Role of oxidative stress in ultrafine particle-induced exacerbation of allergic lung inflammationFrancesca Alessandrini
Division of Environmental Dermatology and Allergy, Helmholtz Zentrum Technische Universität München, ZAUM Center for Allergy and Environment, Helmholtz Zentrum Munchen, Neuherberg, Germany
Am J Respir Crit Care Med 179:984-91. 2009..The effects of ultrafine particle inhalation on allergic airway inflammation are of growing interest. The mechanisms underlying these effects are currently under investigation...
- Soluble iron modulates iron oxide particle-induced inflammatory responses via prostaglandin E(2 )synthesis: In vitro and in vivo studiesIngrid Beck-Speier
Comprehensive Pneumology Center, Institute of Lung Biology and Disease, German Research Center for Environmental Health, D 85764 Neuherberg, Germany
Part Fibre Toxicol 6:34. 2009..In addition, we exposed male WKY rats to monodispersed Fe(2)O(3 )particles by intratracheal instillation (1.3 or 4.0 mg/kg body weight) to examine in vivo inflammation...