Isaac George

Summary

Publications

  1. ncbi request reprint Clinical indication for use and outcomes after inhaled nitric oxide therapy
    Isaac George
    Department of Surgery, Division of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Ann Thorac Surg 82:2161-9. 2006
  2. doi request reprint Association of device surface and biomaterials with immunologic sensitization after mechanical support
    Isaac George
    Department of Surgery, Division of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University, New York, NY, USA
    J Thorac Cardiovasc Surg 135:1372-9. 2008
  3. pmc Myostatin activation in patients with advanced heart failure and after mechanical unloading
    Isaac George
    Division of Cardiothoracic Surgery, Department of Surgery, Columbia University College of Physicians and Surgeons, Milstein Hospital Building, 7GN 435, 177 Fort Washington Avenue, New York, NY 10032, USA
    Eur J Heart Fail 12:444-53. 2010
  4. doi request reprint Stentless bioprosthesis in a valved conduit: implications for pulmonary reconstruction
    Isaac George
    Division of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Ann Thorac Surg 88:2022-4. 2009
  5. ncbi request reprint Effect of clenbuterol on cardiac and skeletal muscle function during left ventricular assist device support
    Isaac George
    Department of Surgery, Division of Cardiothoracic Surgery, Columbia College of Physicians and Surgeons, New York, New York 10032, USA
    J Heart Lung Transplant 25:1084-90. 2006
  6. ncbi request reprint The effect of ischemic time on survival after heart transplantation varies by donor age: an analysis of the United Network for Organ Sharing database
    Mark J Russo
    Division of Cardiothoracic Surgery, Department of Surgery, College of Physicians and Surgeons, Columbia University, New York, USA
    J Thorac Cardiovasc Surg 133:554-9. 2007
  7. doi request reprint Clenbuterol increases lean muscle mass but not endurance in patients with chronic heart failure
    Gayathri Kamalakkannan
    Division of Cardiology, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA
    J Heart Lung Transplant 27:457-61. 2008
  8. pmc Long-term effects of B-type natriuretic peptide infusion after acute myocardial infarction in a rat model
    Isaac George
    Department of Surgery, Division of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Cardiovasc Pharmacol 55:14-20. 2010
  9. doi request reprint Predicting paravalvular regurgitation following transcatheter valve replacement: utility of a novel method for three-dimensional echocardiographic measurements of the aortic annulus
    Rebecca T Hahn
    Columbia University Medical Center New York Presbyterian Hospital and the Cardiovascular Research Foundation, New York, NY 10032, USA
    J Am Soc Echocardiogr 26:1043-52. 2013
  10. pmc Prolonged effects of B-type natriuretic peptide infusion on cardiac remodeling after sustained myocardial injury
    Isaac George
    Division of Cardiothoracic Surgery, Department of Surgery, College of Physicians and Surgeons of Columbia University, New York, New York, USA
    Am J Physiol Heart Circ Physiol 297:H708-17. 2009

Detail Information

Publications62

  1. ncbi request reprint Clinical indication for use and outcomes after inhaled nitric oxide therapy
    Isaac George
    Department of Surgery, Division of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Ann Thorac Surg 82:2161-9. 2006
    ..Inhaled nitric oxide (iNO) use is widespread, but the long-term outcomes after therapy in adult patients remain unknown...
  2. doi request reprint Association of device surface and biomaterials with immunologic sensitization after mechanical support
    Isaac George
    Department of Surgery, Division of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University, New York, NY, USA
    J Thorac Cardiovasc Surg 135:1372-9. 2008
    ....
  3. pmc Myostatin activation in patients with advanced heart failure and after mechanical unloading
    Isaac George
    Division of Cardiothoracic Surgery, Department of Surgery, Columbia University College of Physicians and Surgeons, Milstein Hospital Building, 7GN 435, 177 Fort Washington Avenue, New York, NY 10032, USA
    Eur J Heart Fail 12:444-53. 2010
    ..This study sought to characterize myostatin expression and activation in advanced HF before and after LVAD support...
  4. doi request reprint Stentless bioprosthesis in a valved conduit: implications for pulmonary reconstruction
    Isaac George
    Division of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Ann Thorac Surg 88:2022-4. 2009
    ..We report a case of pulmonary valve replacement and right ventricular outflow tract reconstruction using a stentless bioprosthetic aortic valve and polyester graft as a novel approach after radical pulmonary artery sarcoma resection...
  5. ncbi request reprint Effect of clenbuterol on cardiac and skeletal muscle function during left ventricular assist device support
    Isaac George
    Department of Surgery, Division of Cardiothoracic Surgery, Columbia College of Physicians and Surgeons, New York, New York 10032, USA
    J Heart Lung Transplant 25:1084-90. 2006
    ..High-dose clenbuterol (a selective beta2-adrenergic agonist) has been proposed to promote myocardial recovery during left ventricular assist device (LVAD) support, but its effects on cardiac and skeletal muscle are largely unknown...
  6. ncbi request reprint The effect of ischemic time on survival after heart transplantation varies by donor age: an analysis of the United Network for Organ Sharing database
    Mark J Russo
    Division of Cardiothoracic Surgery, Department of Surgery, College of Physicians and Surgeons, Columbia University, New York, USA
    J Thorac Cardiovasc Surg 133:554-9. 2007
    ..1) To examine the interaction of donor age with ischemic time and their effect on survival and (2) to define ranges of ischemic time associated with differences in survival...
  7. doi request reprint Clenbuterol increases lean muscle mass but not endurance in patients with chronic heart failure
    Gayathri Kamalakkannan
    Division of Cardiology, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA
    J Heart Lung Transplant 27:457-61. 2008
    ..Prior data support combining exercise training with clenbuterol to maximize performance, and on-going studies will evaluate this approach...
  8. pmc Long-term effects of B-type natriuretic peptide infusion after acute myocardial infarction in a rat model
    Isaac George
    Department of Surgery, Division of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Cardiovasc Pharmacol 55:14-20. 2010
    ..We tested the hypothesis that in vivo infusion of BNP would improve cardiac function and affect left ventricular (LV) remodeling in an experimental model of MI...
  9. doi request reprint Predicting paravalvular regurgitation following transcatheter valve replacement: utility of a novel method for three-dimensional echocardiographic measurements of the aortic annulus
    Rebecca T Hahn
    Columbia University Medical Center New York Presbyterian Hospital and the Cardiovascular Research Foundation, New York, NY 10032, USA
    J Am Soc Echocardiogr 26:1043-52. 2013
    ....
  10. pmc Prolonged effects of B-type natriuretic peptide infusion on cardiac remodeling after sustained myocardial injury
    Isaac George
    Division of Cardiothoracic Surgery, Department of Surgery, College of Physicians and Surgeons of Columbia University, New York, New York, USA
    Am J Physiol Heart Circ Physiol 297:H708-17. 2009
    ..Treatment with continuous infusion of BNP preserved LV geometry, improved systolic function, and prevented the progression of systolic HF after persistent ischemic injury...
  11. doi request reprint Erythropoietin derivate improves left ventricular systolic performance and attenuates left ventricular remodeling in rats with myocardial infarct-induced heart failure
    Kai Xu
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    J Cardiovasc Pharmacol 56:506-12. 2010
    ..It is unknown whether EPO alters the left ventricular (LV) remodeling process after ischemic insult. Accordingly, we tested the potential benefits of carbamylated EPO (CEPO) on LV remodeling in rats with myocardial infarction (MI)...
  12. ncbi request reprint Effect of passive cardiac containment on ventricular synchrony and cardiac function in awake dogs
    Isaac George
    Department of Surgery, Division of Cardiothoracic Surgery, Columbia University, College of Physicians and Surgeons, New York, NY, United States
    Eur J Cardiothorac Surg 31:55-64. 2007
    ..The goals of this study were to test whether a left ventricular support device (LVSD) improves LV synchrony and/or affects cardiac performance...
  13. doi request reprint Improving the accuracy of effective orifice area assessment after transcatheter aortic valve replacement: validation of left ventricular outflow tract diameter and pulsed-wave Doppler location and impact of three-dimensional measurements
    Omar K Khalique
    Columbia University Medical Center New York Presbyterian Hospital, New York, New York
    J Am Soc Echocardiogr 28:1283-93. 2015
    ..The aim of this study was to determine the most accurate method for calculating the EOA of the Edwards SAPIEN and SAPIEN XT THVs...
  14. ncbi request reprint Ventricular assist device use for the treatment of acute viral myocarditis
    Veli K Topkara
    Columbia University College of Physicians and Surgeons, Department of Cardiothoracic Surgery, New York, NY 10032, USA
    J Thorac Cardiovasc Surg 131:1190-1. 2006
  15. pmc Matching high-risk recipients with marginal donor hearts is a clinically effective strategy
    Mark J Russo
    Division of Cardiothoracic Surgery, Department of Surgery, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Ann Thorac Surg 87:1066-70; discussion 1071. 2009
    ....
  16. doi request reprint Reversibility of chronic kidney disease and outcomes following aortic valve replacement†
    Marc Najjar
    Division of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University New York Presbyterian Hospital, New York, NY, USA
    Interact Cardiovasc Thorac Surg 21:499-505. 2015
    ..We sought to evaluate the impact of AVR on estimated glomerular filtration rate (eGFR) levels and determine the impact of reversibility of CKD on postoperative outcomes...
  17. doi request reprint Residual Tricuspid Regurgitation following Tricuspid Valve Repair during Concomitant Valve Surgery Worsens Late Survival
    Robert A Sorabella
    Division of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons, New York Presbyterian Hospital, New York, NY
    Heart Surg Forum 18:E226-31. 2015
    ..The impact of residual post-repair TR on late outcomes remains unclear...
  18. doi request reprint Feasibility and Early Safety of Single-Stage Hybrid Coronary Intervention and Valvular Cardiac Surgery
    Isaac George
    Division of Cardiothoracic Surgery, New York Presbyterian Hospital, Columbia University College of Physicians and Surgeons, New York, New York Interventional Cardiology, New York Presbyterian Hospital, Columbia University College of Physicians and Surgeons, New York, New York Electronic address
    Ann Thorac Surg 99:2032-7. 2015
    ..We report the outcomes of a single-stage hybrid strategy in valvular cardiac surgery and explore its effects on operative risk and bleeding...
  19. doi request reprint Transthoracic access for transcatheter aortic valve replacement: technique using the Edwards Sapien Retroflex delivery system
    Isaac George
    Division of Cardiothoracic Surgery, Columbia College of Physicians and Surgeons, New York Presbyterian Hospital, New York, New York Electronic address
    Ann Thorac Surg 98:347-9. 2014
    ....
  20. doi request reprint Management of significant left main coronary disease before and after trans-apical transcatheter aortic valve replacement in a patient with severe and complex arterial disease
    Jean Michel Paradis
    Columbia University Medical Center, New York, New York Cardiovascular Research Foundation, New York, New York
    Catheter Cardiovasc Interv 82:E262-5. 2013
    ..This multifaceted case clearly underlines the importance of a well functioning heart team including the interventional cardiologist, the cardiovascular surgeon, and the echocardiographer...
  21. ncbi request reprint Direct left ventricle-to-coronary artery stent restores perfusion to chronic ischemic swine myocardium
    Geng Hua Yi
    Department of Surgery, Division of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Heart Surg Forum 9:E744-9. 2006
    ..The goal of this study was to examine quantitative changes in myocardial perfusion and possible mechanisms of revascularization with an LV-to-coronary shunt...
  22. ncbi request reprint Discharge to home rates are significantly lower for octogenarians undergoing coronary artery bypass graft surgery
    Hasmet Bardakci
    Division of Cardiothoracic Surgery, College of Physicians and Surgeons, Columbia University New York Presbyterian Hospital, New York, New York 10032, USA
    Ann Thorac Surg 83:483-9. 2007
    ..We sought to evaluate clinical outcomes of octogenarians undergoing CABG using an audited state-wide mandatory database...
  23. pmc Very low intravenous contrast volume protocol for computed tomography angiography providing comprehensive cardiac and vascular assessment prior to transcatheter aortic valve replacement in patients with chronic kidney disease
    Todd C Pulerwitz
    Department of Medicine, Division of Cardiology, Columbia University Medical Center and New York Presbyterian Hospital, New York, NY, USA
    J Cardiovasc Comput Tomogr 10:316-21. 2016
    ..The prevalence of chronic kidney disease (CKD) is high in this population, and thus a very low contrast volume (VLCV) computed tomography angiography (CTA) protocol providing comprehensive cardiac and vascular imaging would be valuable...
  24. doi request reprint Practical considerations for optimizing cardiac computed tomography protocols for comprehensive acquisition prior to transcatheter aortic valve replacement
    Omar K Khalique
    Columbia University Medical Center New York Presbyterian Hospital, New York, NY, USA Electronic address
    J Cardiovasc Comput Tomogr 10:364-74. 2016
    ....
  25. doi request reprint Short-term outcomes in adult cardiac surgery in the use of del Nido cardioplegia solution
    Takeyoshi Ota
    Department of Surgery, Division of Cardiothoracic Surgery, Columbia University, New York, NY, USA Department of Surgery, Section of Cardiac and Thoracic Surgery, The University of Chicago, Chicago, IL, USA
    Perfusion 31:27-33. 2016
    ..We retrospectively assessed the short-term (in-hospital) clinical outcomes of patients undergoing aortic valve replacement (AVR) using del Nido cardioplegia solution, comparing it to conventional multi-dose whole blood cardioplegia...
  26. pmc Attenuation of the unfolded protein response and endoplasmic reticulum stress after mechanical unloading in dilated cardiomyopathy
    Estibaliz Castillero
    Division of Cardiothoracic Surgery, New York Presbyterian Hospital College of Physicians and Surgeons of Columbia University, New York, New York
    Am J Physiol Heart Circ Physiol 309:H459-70. 2015
    ..UPR activation and apoptosis are reduced after mechanical unloading, which may be mediated by the improvement of Ca(2+) handling in patients with advanced HF. These changes may impact the potential for myocardial recovery. ..
  27. doi request reprint Age alone should not preclude surgery: contemporary outcomes after aortic valve replacement in nonagenarians
    Isaac George
    Division of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons, New York Presbyterian Hospital, New York, NY Electronic address
    J Thorac Cardiovasc Surg 148:1360-1369.e1. 2014
    ..We, therefore, evaluated the outcomes after surgical aortic valve replacement (SAVR) in nonagenarians (age, >90 years) at our institution during an 11-year period...
  28. doi request reprint Impact of major bleeding on long-term mortality in anemic versus nonanemic patients undergoing percutaneous coronary intervention using bivalirudin
    Ziad A Ali
    Cardiac Catheterization Laboratory, Cardiovascular Institute, Division of Cardiology, Mount Sinai Hospital and School of Medicine, New York, New York Center for Interventional Vascular Therapy, Columbia University, New York, New York Cardiovascular Research Foundation, New York, New York Electronic address
    Am J Cardiol 113:1481-6. 2014
    ..25, 95% CI 0.52 to 3.03, p = 0.62). In patients who underwent PCI with bivalirudin therapy, major bleeding is associated with early and long-term mortality, which is more pronounced in patients with baseline anemia. ..
  29. doi request reprint Aortic root and right ventricular outflow tract reconstruction using composite biological valved conduits after failed Ross procedure
    Mark J Russo
    Department of Surgery, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Ann Thorac Surg 91:e87-9. 2011
    ..We describe a novel approach to this complication using composite biological valved conduits comprised of stentless bioprosthetic valves and polyester grafts...
  30. doi request reprint β-adrenergic receptor blockade reduces endoplasmic reticulum stress and normalizes calcium handling in a coronary embolization model of heart failure in canines
    Isaac George
    Division of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University, New York, NY, USA
    Cardiovasc Res 91:447-55. 2011
    ..However, the role of ER stress in β-blocker therapy for congestive heart failure (CHF) has not been studied. This study examined ER stress in CHF and evaluated its role in β-blocker therapy in a canine model of ischaemic CHF...
  31. doi request reprint Injuries to the Aorta, Aortic Annulus, and Left Ventricle During Transcatheter Aortic Valve Replacement: Management and Outcomes
    Nathaniel B Langer
    From the Division of Cardiothoracic Surgery N B L, D L, I G and Division of Cardiology N B H, T M N, O K K, T P V, J W, J T, R H, R T H, M L, S K, I G, Columbia University College of Physicians and Surgeons, New York, NY
    Circ Cardiovasc Interv 10:. 2017
    ..The goal of this article is to provide an overview of current management and prevention strategies for major complications involving the aorta, aortic valve annulus, and left ventricle...
  32. doi request reprint Bicuspid aortic valve increases risk of permanent pacemaker implant following aortic root replacement
    Laura Guglielmetti
    Division of Cardiothoracic Surgery, New York Presbyterian Hospital Columbia University College of Physicians and Surgeons, New York, NY, USA
    Eur J Cardiothorac Surg 50:497-503. 2016
    ..We aimed to assess the incidence and possible differences in postoperative conduction delay after aortic root replacement (ARR) in bicuspid aortic valve (BAV) patients compared with a tricuspid aortic valve (TAV)...
  33. pmc The Use of Hypothermic Circulatory Arrest During Heart Transplantation Does Not Worsen Posttransplant Survival
    Robert A Sorabella
    Division of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons, New York Presbyterian Hospital, New York, New York
    Ann Thorac Surg 102:1260-5. 2016
    ..The aim of this study is to determine the impact of HCA during heart transplantation on posttransplant outcomes...
  34. pmc Feasibility and safety of continuous retrograde administration of Del Nido cardioplegia: a case series
    Marc Najjar
    Department of Surgery, Division of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University, New York Presbyterian Hospital, MHB 7GN 435, 177 Fort Washington Ave, New York, 10032, NY, USA
    J Cardiothorac Surg 10:176. 2015
    ..We specifically report the outcomes of patients undergoing reoperative cardiac surgery after previous coronary artery bypass grafting with a patent internal mammary artery (IMA)...
  35. doi request reprint Acute kidney injury following surgical aortic valve replacement
    Marc Najjar
    New York Presbyterian Hospital College of Physicians and Surgeons of Columbia University, New York, New York
    J Card Surg 30:631-9. 2015
    ..Acute kidney injury (AKI) is a significant complication of surgical aortic valve replacement (SAVR). This study sought to describe AKI following SAVR, its risk factors, predictors and effect on long-term survival...
  36. doi request reprint Aortic Root Replacement in Octogenarians Offers Acceptable Perioperative and Late Outcomes
    Robert A Sorabella
    Division of Cardiothoracic Surgery, New York Presbyterian Hospital, Columbia University College of Physicians and Surgeons, New York, New York
    Ann Thorac Surg 101:967-72. 2016
    ..The aim of this study is to evaluate the perioperative and late outcomes of octogenarians undergoing aortic root replacement in comparison with younger patients...
  37. doi request reprint Aortic stenosis and coronary artery disease: what do we know? What don't we know? A comprehensive review of the literature with proposed treatment algorithms
    Jean Michel Paradis
    Columbia University Medical Center, New York, NY, USA Cardiovascular Research Foundation, New York, NY, USA Quebec Heart and Lung Institute, Quebec, Canada
    Eur Heart J 35:2069-82. 2014
    ..This article includes a comprehensive review of the literature and seeks to describe the actual knowledge on the topic of aortic stenosis and concomitant coronary artery disease. ..
  38. doi request reprint Stent exteriorization facilitates surgical repair for large-bore sheath complications
    Isaac George
    Divisions of Cardiothoracic Surgery and Cardiology, College of Physicians and Surgeons of Columbia University, New York, New York Center for Interventional Vascular Therapeutics, College of Physicians and Surgeons of Columbia University, New York, New York
    Catheter Cardiovasc Interv 82:E257-61. 2013
    ..We describe a patient with a complex, post-dissection, descending aortic aneurysm who required TEVAR and had a vascular access complication repaired with stent exteriorization with open repair...
  39. doi request reprint Efficacy and safety of postdilatation to reduce paravalvular regurgitation during balloon-expandable transcatheter aortic valve replacement
    Benoit Daneault
    Columbia University Medical Center New York Presbyterian Hospital and the Cardiovascular Research Foundation, New York, NY 10032, USA
    Circ Cardiovasc Interv 6:85-91. 2013
    ..Postdilatation (PD) has been proposed to treat PVR without being formally studied. We performed a study to evaluate the safety and efficacy of PD after balloon expandable TAVR...
  40. ncbi request reprint Adult-age donors offer acceptable long-term survival to pediatric heart transplant recipients: an analysis of the United Network of Organ Sharing database
    Mark J Russo
    Division of Cardiothoracic Surgery, Department of Surgery, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    J Thorac Cardiovasc Surg 132:1208-12. 2006
    ....
  41. ncbi request reprint A polymerized bovine hemoglobin oxygen carrier preserves regional myocardial function and reduces infarct size after acute myocardial ischemia
    Isaac George
    Department of Surgery, Division of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons, New York, NY, and The Jack H Skirball Center for Cardiovascular Research, Cardiovascular Research Foundation, Orangeburg, NY 10962, USA
    Am J Physiol Heart Circ Physiol 291:H1126-37. 2006
    ..05) and 49% after Phe (P=not significant). HBOC-201 administration after induction of severe myocardial ischemia by acute coronary stenosis reduces infarct size and improves myocardial viability...
  42. ncbi request reprint Predictors and outcomes of continuous veno-venous hemodialysis use after implantation of a left ventricular assist device
    Veli K Topkara
    Department of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Heart Lung Transplant 25:404-8. 2006
    ..Post-operative renal failure is a common complication after left ventricular assist device (LVAD) implantation. This study was designed to evaluate predictors and outcomes of acute renal failure after LVAD insertion...
  43. doi request reprint Vascular inflammation and abnormal aortic histomorphometry in patients after pulsatile- and continuous-flow left ventricular assist device placement
    Mike Lee
    Department of Medicine, Division of Cardiology, Columbia University Medical Center, New York, New York
    J Heart Lung Transplant 35:1085-91. 2016
    ..We aimed to identify histomorphometric, structural and inflammatory changes after pulsatile- and continuous-flow left ventricular assist device placement...
  44. doi request reprint Bridging Anticoagulation After Mechanical Aortic Heart Valve Replacement: A Questionable Routine
    Laura C Guglielmetti
    Division of Cardiothoracic Surgery, New York Presbyterian Hospital, Columbia University College of Physicians and Surgeons, New York, New York
    Ann Thorac Surg 102:48-54. 2016
    ....
  45. pmc Dynamics and prognostic role of galectin-3 in patients with advanced heart failure, during left ventricular assist device support and following heart transplantation
    Ellie Coromilas
    Department of Medicine, Division of Cardiology, Columbia University Medical Center, 166 Fort Washington Avenue, New York, NY, 10032, USA
    BMC Cardiovasc Disord 16:138. 2016
    ..We examined the utility of galectin-3 as a marker of the severity of HF, the response of galectin-3 levels to ventricular assist device (LVAD) implantation or heart transplantation (HTx), and its use as a prognostic indicator...
  46. doi request reprint Transcatheter Valve Implantation in Failed Surgically Inserted Bioprosthesis: Review and Practical Guide to Echocardiographic Imaging in Valve-in-Valve Procedures
    Nadira B Hamid
    Columbia University Medical Center, New York Presbyterian Hospital, New York, New York
    JACC Cardiovasc Imaging 8:960-79. 2015
    ..In this review, we summarize key echocardiographic requirements for optimal patient selection, procedural guidance, and immediate post-procedural assessment for VIV procedures. ..
  47. doi request reprint Quantity and location of aortic valve complex calcification predicts severity and location of paravalvular regurgitation and frequency of post-dilation after balloon-expandable transcatheter aortic valve replacement
    Omar K Khalique
    Columbia University Medical Center New York Presbyterian Hospital, New York, New York
    JACC Cardiovasc Interv 7:885-94. 2014
    ..This study sought to determine the impact of quantity and location of aortic valve calcification (AVC) on paravalvular regurgitation (PVR) and rates of post-dilation (PD) immediately after transcatheter aortic valve replacement (TAVR)...
  48. doi request reprint Transcatheter valve-in-valve implantation for early prosthetic valve degeneration in aortic and mitral positions
    Kentaro Yamane
    Division of Cardiothoracic Surgery, Department of Surgery, Columbia University College of Physicians and Surgeons, New York, New York
    Ann Thorac Surg 98:318-21. 2014
    ..Here we report a case of early structural valve degeneration in the aortic and mitral position in a patient with chronic hemodialysis successfully treated with transthoracic transcatheter valve-in-valve implantation. ..
  49. pmc Deep RNA sequencing reveals dynamic regulation of myocardial noncoding RNAs in failing human heart and remodeling with mechanical circulatory support
    Kai Chien Yang
    Department of Developmental Biology K C Y, J M N and Center for Cardiovascular Research, Division of Cardiology, Department of Internal Medicine K A Y, A Y P, V K T, G A E, D L M, Washington University Medical School, St Louis, MO Division of Cardiothoracic Surgery, New York Presbyterian Hospital, Columbia University College of Physicians and Surgeons, New York, NY I G and Department of Surgery, University of Maryland School of Medicine, Baltimore F H C Dr Yang s current affiliation is the Department of Pharmacology, National Taiwan University School of Medicine, Taipei, Taiwan
    Circulation 129:1009-21. 2014
    ....
  50. doi request reprint A stepwise progression in the treatment of cardiogenic shock
    Ari Pollack
    Department of Medicine, New York Presbyterian Hospital Columbia University Medical Center, New York, New York, USA
    Heart Lung 41:500-4. 2012
    ..We also review the literature with regard to the use of percutaneous left ventricular assist devices in the setting of cardiogenic shock...
  51. pmc Myocardial function improved by electromagnetic field induction of stress protein hsp70
    Isaac George
    Department of Surgery, Division of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Cell Physiol 216:816-23. 2008
    ..In conclusion, non-invasive EMF induction of hsp70 preserved myocardial function and has the potential to improve tolerance to ischemic injury...
  52. doi request reprint Mitraclip Followed by Surgical Aortic Valve Replacement: Hybrid Techniques for Regurgitant Aortic and Mitral Valve Disease
    Kyle Eudailey
    Division of Cardiothoracic Surgery, New York Presbyterian Hospital Columbia College of Physicians and Surgeons, New York Presbyterian Hospital, New York, New York
    Ann Thorac Surg 102:e83-5. 2016
    ..We expect these techniques to play an increasingly larger role in the treatment algorithm for high-risk multivalve disease. ..
  53. doi request reprint Cardiogenic Shock From Coronary Compression: A Difficult Diagnosis But Easy Fix
    Nathaniel B Langer
    Division of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons, New York, New York
    Ann Thorac Surg 101:e111-3. 2016
    ..Although both patients' cardiac function was initially severely impaired, neither patient had permanent cardiac damage and both were successfully discharged home...
  54. doi request reprint Transcatheter mitral valve replacement: design implications, potential pitfalls and outcomes assessment
    Gilbert H L Tang
    From the Section of Cardiothoracic Surgery, Westchester Medical Center, New York Medical College, Valhalla, NY Division of Cardiothoracic Surgery, Division of Cardiology, New York Presbyterian Hospital, College of Physicians and Surgeons of Columbia University, New York, NY Department of Cardiothoracic Surgery, St Thomas Hospital, London, United Kingdom and Division of Cardiovascular Surgery, University of Pennsylvania Medical Center, Philadelphia, PA
    Cardiol Rev 23:290-6. 2015
    ..This review aims to critically evaluate design implications in TMVR in the context of mitral valve disease, imaging prerequisites, procedural approaches, potential complications, and outcomes assessment. ..
  55. pmc Early Operation for Endocarditis Complicated by Preoperative Cerebral Emboli Is Not Associated With Worsened Outcomes
    Robert A Sorabella
    Division of Cardiothoracic Surgery, New York Presbyterian Hospital, Columbia University College of Physicians and Surgeons, New York, New York
    Ann Thorac Surg 100:501-8. 2015
    ..Our aim was to compare outcomes of IE patients who undergo surgical intervention early after diagnosis of septic cerebral emboli with outcomes of patients without preoperative emboli...
  56. pmc Neutrophil gelatinase-associated lipocalin and cystatin C for the prediction of clinical events in patients with advanced heart failure and after ventricular assist device placement
    Katherine B Pronschinske
    Department of Medicine, Division of Cardiology, Columbia University Medical Center, New York, New York
    J Heart Lung Transplant 33:1215-22. 2014
    ..We evaluated neutrophil gelatinase-associated lipocalin (NGAL) and cystatin C compared with established markers of renal function in patients with heart failure (HF) because they might improve prognostic assessment of patients with HF...
  57. pmc Cardiac myostatin upregulation occurs immediately after myocardial ischemia and is involved in skeletal muscle activation of atrophy
    Estibaliz Castillero
    Division of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University, New York, NY, United States
    Biochem Biophys Res Commun 457:106-11. 2015
    ....
  58. pmc Myocardial protection using del nido cardioplegia solution in adult reoperative aortic valve surgery
    Robert A Sorabella
    Division of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University, New York Presbyterian Hospital, New York, New York
    J Card Surg 29:445-9. 2014
    ..Our aim in this study is to determine if this solution can be used safely and effectively in an adult, reoperative population...
  59. pmc Rat model of veno-arterial extracorporeal membrane oxygenation
    Ayyaz A Ali
    Center for Interventional Vascular Therapy, Division of Cardiology, New York Presbyterian Hospital and Columbia University, 161 Fort Washington Avenue, Herbert Irving Pavilion, 6th Floor, New York, NY 10032, USA
    J Transl Med 12:37. 2014
    ..We aim to develop a rat model of veno-arterial extracorporeal membrane oxygenation (VA-ECMO)...
  60. doi request reprint Acute kidney injury after aortic valve replacement: incidence, risk factors and outcomes
    Marc Najjar
    Division of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University New York Presbyterian Hospital, MHB 7GN 435, 177 Fort Washington Ave, New York, NY 10032, USA
    Expert Rev Cardiovasc Ther 13:301-16. 2015
    ..AKI confers up to a fourfold increase in 1-year mortality. Finally, hospital length of stay was significantly increased in patients with AKI in both SAVR and TAVR groups, with increases up to 3- and 2.5-times, respectively. ..
  61. doi request reprint Tetrahydrobiopterin determines vascular remodeling through enhanced endothelial cell survival and regeneration
    Ziad A Ali
    Center for Interventional Vascular Therapy, Division of Cardiology, New York Presbyterian Hospital and Columbia University, New York, NY Z A A, W Q, I G Cardiovascular Research Foundation, New York, NY Z A A Department of Cardiovascular Medicine, John Radcliffe Hospital and University of Oxford, Oxford, United Kingdom Z A A, R R, G D, E M, C B, K M C Cardiovascular Division, King s College Hospital, London, United Kingdom Y H, Q Xiao, Q Xu and Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom D R G
    Circulation 128:S50-8. 2013
    ..Nitric oxide (NO) is a key regulator of EC and endothelial progenitor cell function, but the pathophysiological mechanisms that regulate endothelial NO synthase in endothelial regeneration remain unclear...
  62. ncbi request reprint Bradycardic therapy improves left ventricular function and remodeling in dogs with coronary embolization-induced chronic heart failure
    Yanping Cheng
    The Institute of Molecular and Experimental Therapeutics, East China Normal University, Shanghai, and Department of Cardiac Nephrology, Chinese PLA General Hospital, Beijing, People s Republic of China
    J Pharmacol Exp Ther 321:469-76. 2007
    ..Restored protein levels of SERCA2a and improved function of RyR2 may be important mechanisms associated with cilobradine therapy...