Joel M Gelfand

Summary

Publications

  1. ncbi request reprint Surrogate endpoints for the treatment of venous leg ulcers
    Joel M Gelfand
    Department of Dermatology and the Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Invest Dermatol 119:1420-5. 2002
  2. pmc Patient-reported reasons for the discontinuation of commonly used treatments for moderate to severe psoriasis
    Howa Yeung
    Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Am Acad Dermatol 68:64-72. 2013
  3. pmc Prevalence of metabolic syndrome in patients with psoriasis: a population-based study in the United Kingdom
    Sinead M Langan
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
    J Invest Dermatol 132:556-62. 2012
  4. pmc Variation in dermatologist beliefs about the safety and effectiveness of treatments for moderate to severe psoriasis
    Katrina Abuabara
    Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Am Acad Dermatol 68:262-9. 2013
  5. pmc Comparative effectiveness of commonly used systemic treatments or phototherapy for moderate to severe plaque psoriasis in the clinical practice setting
    Joel M Gelfand
    Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA
    Arch Dermatol 148:487-94. 2012
  6. doi request reprint Immunosuppressant medications and mortality in inflammatory bowel disease
    James D Lewis
    Division of Gastroenterology, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Am J Gastroenterol 103:1428-35; quiz 1436. 2008
  7. pmc Comparative effectiveness of less commonly used systemic monotherapies and common combination therapies for moderate to severe psoriasis in the clinical setting
    Junko Takeshita
    Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania Department of Epidemiology and Biostatistics, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania Electronic address
    J Am Acad Dermatol 71:1167-75. 2014
  8. pmc Risk of moderate to advanced kidney disease in patients with psoriasis: population based cohort study
    Joy Wan
    Department of Dermatology, University of Pennsylvania, Philadelphia, PA 19104, USA
    BMJ 347:f5961. 2013
  9. pmc Psoriasis and cardiovascular risk: strength in numbers, part II
    Joel M Gelfand
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Invest Dermatol 131:1007-10. 2011
  10. pmc Attributable risk estimate of severe psoriasis on major cardiovascular events
    Nehal N Mehta
    Preventive Cardiology, Division of Cardiovascular Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, USA
    Am J Med 124:775.e1-6. 2011

Collaborators

Detail Information

Publications62

  1. ncbi request reprint Surrogate endpoints for the treatment of venous leg ulcers
    Joel M Gelfand
    Department of Dermatology and the Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Invest Dermatol 119:1420-5. 2002
    ....
  2. pmc Patient-reported reasons for the discontinuation of commonly used treatments for moderate to severe psoriasis
    Howa Yeung
    Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Am Acad Dermatol 68:64-72. 2013
    ..Despite widespread dissatisfaction and low treatment persistence in moderate to severe psoriasis, patients' reasons behind treatment discontinuation remain poorly understood...
  3. pmc Prevalence of metabolic syndrome in patients with psoriasis: a population-based study in the United Kingdom
    Sinead M Langan
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
    J Invest Dermatol 132:556-62. 2012
    ..These findings suggest that screening for metabolic disease should be considered for psoriasis, especially when it is severe...
  4. pmc Variation in dermatologist beliefs about the safety and effectiveness of treatments for moderate to severe psoriasis
    Katrina Abuabara
    Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Am Acad Dermatol 68:262-9. 2013
    ..Physician perceptions can influence prescribing patterns and patient outcomes, and may help to explain variations in clinical practice...
  5. pmc Comparative effectiveness of commonly used systemic treatments or phototherapy for moderate to severe plaque psoriasis in the clinical practice setting
    Joel M Gelfand
    Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA
    Arch Dermatol 148:487-94. 2012
    ..To compare the effectiveness of biologic systemic therapy, nonbiologic systemic therapy, and phototherapy for treatment of psoriasis...
  6. doi request reprint Immunosuppressant medications and mortality in inflammatory bowel disease
    James D Lewis
    Division of Gastroenterology, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Am J Gastroenterol 103:1428-35; quiz 1436. 2008
    ..This study examined whether treatment of Crohn's disease (CD) and ulcerative colitis (UC) with immunosuppressant medications was associated with an increased risk of death in the era prior to antitumor necrosis factor (TNF) therapies...
  7. pmc Comparative effectiveness of less commonly used systemic monotherapies and common combination therapies for moderate to severe psoriasis in the clinical setting
    Junko Takeshita
    Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania Department of Epidemiology and Biostatistics, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania Electronic address
    J Am Acad Dermatol 71:1167-75. 2014
    ..The effectiveness of psoriasis therapies in real-world settings remains relatively unknown...
  8. pmc Risk of moderate to advanced kidney disease in patients with psoriasis: population based cohort study
    Joy Wan
    Department of Dermatology, University of Pennsylvania, Philadelphia, PA 19104, USA
    BMJ 347:f5961. 2013
    ..To determine the risk of chronic kidney disease in patients with psoriasis...
  9. pmc Psoriasis and cardiovascular risk: strength in numbers, part II
    Joel M Gelfand
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Invest Dermatol 131:1007-10. 2011
    ....
  10. pmc Attributable risk estimate of severe psoriasis on major cardiovascular events
    Nehal N Mehta
    Preventive Cardiology, Division of Cardiovascular Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, USA
    Am J Med 124:775.e1-6. 2011
    ..We compared the risk of major adverse cardiac events between patients with psoriasis and the general population and estimated the attributable risk of severe psoriasis...
  11. ncbi request reprint The risk of mortality in patients with psoriasis: results from a population-based study
    Joel M Gelfand
    MSCE, Department of Dermatology, University of Pennsylvania School of Medicine, 2 Maloney Bldg, 3600 Spruce St, Philadelphia, PA 19104, USA
    Arch Dermatol 143:1493-9. 2007
    ..To determine the risk of mortality in patients with psoriasis...
  12. pmc Patients with severe psoriasis are at increased risk of cardiovascular mortality: cohort study using the General Practice Research Database
    Nehal N Mehta
    Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Eur Heart J 31:1000-6. 2010
    ..We conducted a cohort study using the General Practice Research Database to determine if severe psoriasis patients have an increased risk of cardiovascular (CV) mortality...
  13. ncbi request reprint Prevalence of cardiovascular risk factors in patients with psoriasis
    Andrea L Neimann
    Dermatology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Am Acad Dermatol 55:829-35. 2006
    ..Limited population-based data exist on this association, and few studies have determined which factors are independently associated with psoriasis...
  14. pmc The risk of stroke in patients with psoriasis
    Joel M Gelfand
    Department of Dermatology, University of Pennsylvania School of Medicine, Pennsylvania, PA 19104, USA
    J Invest Dermatol 129:2411-8. 2009
    ..Patients with psoriasis, particularly if severe, have an increased risk of stroke that is not explained by major stroke risk factors identified in routine medical care...
  15. pmc Risk of mortality in patients with psoriatic arthritis, rheumatoid arthritis and psoriasis: a longitudinal cohort study
    Alexis Ogdie
    Division of Rheumatology, Center for Clinical Epidemiology and Biostatistics, Center for Pharmacoepidemiology Research and Training, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Ann Rheum Dis 73:149-53. 2014
    ..The objective of this study was to examine the risk of mortality in patients with PsA compared with matched controls, patients with psoriasis and those with rheumatoid arthritis (RA)...
  16. pmc Increased risk of diabetes mellitus and likelihood of receiving diabetes mellitus treatment in patients with psoriasis
    Rahat S Azfar
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA 16104, USA
    Arch Dermatol 148:995-1000. 2012
    ..To assess the risk of incident diabetes mellitus (DM) in patients with psoriasis and to evaluate DM treatment patterns among patients with psoriasis and incident DM...
  17. pmc Dermatologist preferences for first-line therapy of moderate to severe psoriasis in healthy adult patients
    Joy Wan
    Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Am Acad Dermatol 66:376-86. 2012
    ..Despite increasing therapies for moderate to severe psoriasis, dermatologists' treatment preferences are unknown...
  18. pmc The risk of depression, anxiety, and suicidality in patients with psoriasis: a population-based cohort study
    Shanu Kohli Kurd
    Department of Medicine, University of Pennsylvania, 3600 Spruce Street, Philadelphia, PA 19104, USA
    Arch Dermatol 146:891-5. 2010
    ..To determine the incidence of depression, anxiety, and suicidality in patients with psoriasis compared with the general population...
  19. ncbi request reprint Risk of myocardial infarction in patients with psoriasis
    Joel M Gelfand
    Department of Dermatology and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA 19104, USA
    JAMA 296:1735-41. 2006
    ..Psoriasis has been associated with cardiovascular diseases, but has only been investigated in hospital-based studies that did not control for major cardiovascular risk factors...
  20. ncbi request reprint The prevalence of psoriasis in African Americans: results from a population-based study
    Joel M Gelfand
    Department of Dermatology and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, PA 19104, USA
    J Am Acad Dermatol 52:23-6. 2005
    ..The prevalence of psoriasis in African Americans has been previously reported as rare. However, there have been no population-based studies to assess the prevalence and burden of psoriasis in African Americans...
  21. pmc Biologic therapy adherence, discontinuation, switching, and restarting among patients with psoriasis in the US Medicare population
    Jalpa A Doshi
    Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania Leonard Davis Institute of Health Economics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania Electronic address
    J Am Acad Dermatol 74:1057-1065.e4. 2016
    ..Studies indicate adherence to biologics among patients with psoriasis is low, yet little is known about their use in the Medicare population...
  22. ncbi request reprint Prevalence and treatment of psoriasis in the United Kingdom: a population-based study
    Joel M Gelfand
    Center for Clinical Epidemiology and Biostatistics, and Department of Dermatology, University of Pennsylvania, 3600 Spruce Street, 2 Maloney Building, Philadelphia, PA 19104, USA
    Arch Dermatol 141:1537-41. 2005
    ..To measure the prevalence and treatment of psoriasis in the United Kingdom...
  23. pmc Is there truly a risk of lymphoma from biologic therapies?
    Erica Dommasch
    Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Dermatol Ther 22:418-30. 2009
    ..Continued vigilance is warranted; however, in the appropriate patient, the risk-to-benefit profile of psoriasis treatment with respect to lymphoma risk appears highly favorable...
  24. ncbi request reprint Epidemiology of psoriatic arthritis in the population of the United States
    Joel M Gelfand
    Department of Dermatology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Am Acad Dermatol 53:573. 2005
    ..Estimates of the prevalence of psoriatic arthritis vary widely and are usually not determined by population-based studies...
  25. pmc Patient-reported outcomes for psoriasis patients with clear versus almost clear skin in the clinical setting
    Junko Takeshita
    Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania Electronic address
    J Am Acad Dermatol 71:633-41. 2014
    ..There is little evidence to guide the establishment of treatment goals for moderate to severe psoriasis in the clinical setting...
  26. pmc Risk of major cardiovascular events in patients with psoriatic arthritis, psoriasis and rheumatoid arthritis: a population-based cohort study
    Alexis Ogdie
    Division of Rheumatology, Center for Clinical Epidemiology and Biostatistics, Center for Pharmacoepidemiology Research and Training, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Ann Rheum Dis 74:326-32. 2015
    ....
  27. pmc Prevalence and treatment patterns of psoriatic arthritis in the UK
    Alexis Ogdie
    Division of Rheumatology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, 8 Penn Tower, 1 Convention Ave, Philadelphia, PA 19104, USA
    Rheumatology (Oxford) 52:568-75. 2013
    ....
  28. pmc Oral curcumin in the treatment of moderate to severe psoriasis vulgaris: A prospective clinical trial
    Shanu Kohli Kurd
    Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Am Acad Dermatol 58:625-31. 2008
    ..There is a need for safe, inexpensive, and effective psoriasis therapies. Many anecdotal accounts of patients' successful treatment with the alternative medicine curcumin exist...
  29. pmc Topical resiquimod can induce disease regression and enhance T-cell effector functions in cutaneous T-cell lymphoma
    Alain H Rook
    Department of Dermatology and the Center for Clinical Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
    Blood 126:1452-61. 2015
    ..This trial was registered at www.clinicaltrials.gov as #NCT813320. ..
  30. pmc Reliability and convergent validity of the cutaneous sarcoidosis activity and morphology instrument for assessing cutaneous sarcoidosis
    Misha Rosenbach
    Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA
    JAMA Dermatol 149:550-6. 2013
    ....
  31. pmc Metabolic syndrome in patients with psoriatic disease
    Joel M Gelfand
    Department of Dermatology and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA
    J Rheumatol Suppl 89:24-8. 2012
    ..Further research will be necessary to establish the directionality of this association and to explore the effect of treatment on these comorbid diseases...
  32. pmc Systemic and vascular inflammation in patients with moderate to severe psoriasis as measured by [18F]-fluorodeoxyglucose positron emission tomography-computed tomography (FDG-PET/CT): a pilot study
    Nehal N Mehta
    Cardiovascular Institute, University of Pennsylvania School of Medicine, 6 Penn Tower, Philadelphia, PA 19104, USA
    Arch Dermatol 147:1031-9. 2011
    ..To evaluate the feasibility of using [18F]-fluorodeoxyglucose positron emission tomography-computed tomography (FDG-PET/CT) to detect and quantify systemic inflammation in patients with psoriasis...
  33. pmc The risk of infection and malignancy with tumor necrosis factor antagonists in adults with psoriatic disease: a systematic review and meta-analysis of randomized controlled trials
    Erica D Dommasch
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Am Acad Dermatol 64:1035-50. 2011
    ..There is a need to better understand the safety of tumor necrosis factor (TNF) inhibitors in patients with psoriatic disease in whom TNF inhibitors are frequently used as monotherapy...
  34. ncbi request reprint The risk of lymphoma in patients with psoriasis
    Joel M Gelfand
    Department of Dermatology and Center for Clinical Epidemiology and Biostatistics University of Pennsylvania, Philadelphia, 19104, USA
    J Invest Dermatol 126:2194-201. 2006
    ..Although patients with psoriasis have an increased relative risk of lymphoma, the absolute risk attributable to psoriasis is low given that lymphoma is a rare disease and the magnitude of association is modest...
  35. pmc Test characteristics of high-resolution ultrasound in the preoperative assessment of margins of basal cell and squamous cell carcinoma in patients undergoing Mohs micrographic surgery
    Anokhi Jambusaria-Pahlajani
    Department of Dermatology, University of Pennsylvannia, Philadelphia, Pennsylvania, USA
    Dermatol Surg 35:9-15; discussion 15-6. 2009
    ..Noninvasive techniques to assess subclinical spread of nonmelanoma skin cancer (NMSC) may improve surgical precision. High-resolution ultrasound has shown promise in evaluating the extent of NMSC...
  36. doi request reprint The risk of fracture among patients with psoriatic arthritis and psoriasis: a population-based study
    Alexis Ogdie
    Division of Rheumatology, Center for Clinical Epidemiology and Biostatistics, Center for Pharmacoepidemiology Research and Training, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Ann Rheum Dis . 2017
    ..To determine the risk of fracture and osteoporosis among patients with psoriatic arthritis (PsA) and psoriasis, compared with the general population and patients with rheumatoid arthritis (RA)...
  37. pmc Retrospective analysis of beta-blocker instituted for treatment of hemangiomas (RABBIT study)
    Derek H Chu
    Hospital of the University of Pennsylvania, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
    Clin Pediatr (Phila) 53:1084-90. 2014
    ..To evaluate the safety and efficacy of our institutional beta-blocker protocol for treatment of complicated infantile hemangiomas (IH)...
  38. pmc Reliability and validity of mobile teledermatology in human immunodeficiency virus-positive patients in Botswana: a pilot study
    Rahat S Azfar
    Department of Dermatology, University of Pennsylvania, Philadelphia2Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia
    JAMA Dermatol 150:601-7. 2014
    ..Mobile teledermatology may increase access to care...
  39. pmc Aortic vascular inflammation in psoriasis is associated with HDL particle size and concentration: a pilot study
    Yiding Yu
    Cardiovascular Institute, University of Pennsylvania 6 Penn Tower, Philadelphia, Pennsylvania, USA
    Am J Cardiovasc Dis 2:285-92. 2012
    ..These findings suggest that HDL particle characteristics may play an important role in psoriatic vascular inflammation and CVD...
  40. pmc Curcuminoids activate p38 MAP kinases and promote UVB-dependent signalling in keratinocytes
    Elias E Ayli
    Department of Dermatology, University of Pennsylvania Medical School, Philadelphia, PA, USA
    Exp Dermatol 19:493-500. 2010
    ..Curcuminoids also synergize with UVB to enhance p53 phosphorylation. The findings provide a rationale for testing curcuminoids in disorders associated with impaired p53 function or in which UVB-treatment is efficacious...
  41. pmc The prevalence of previously diagnosed and undiagnosed psoriasis in US adults: results from NHANES 2003-2004
    Shanu Kohli Kurd
    Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Am Acad Dermatol 60:218-24. 2009
    ..Psoriasis is a predictor of morbidity. It is important to determine the extent to which psoriasis remains undiagnosed...
  42. pmc Quantification of atherosclerotic plaque activity and vascular inflammation using [18-F] fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT)
    Nehal N Mehta
    Division of Cardiovascular Medicine, University of Pennsylvania, Perelman School of Medicine, USA
    J Vis Exp . 2012
    ..These approaches may be applied to assess vascular inflammation in various study samples of interest in a consistent fashion as we have shown in several prior publications...
  43. pmc Psoriasis and Cardiovascular Risk: Strength in Numbers Part 3
    Alexis Ogdie
    Departmnet of Medicine Rheumatology, Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennslyvania, USA
    J Invest Dermatol 135:2148-50. 2015
    ....
  44. doi request reprint High clinical response rate of Sezary syndrome to immunomodulatory therapies: prognostic markers of response
    Brian A Raphael
    Department of Dermatology, The Hospital at the University of Pennsylvania, Philadelphia, USA
    Arch Dermatol 147:1410-5. 2011
    ..To quantify response rates of Sézary syndrome (SS) to multimodality immunomodulatory therapy and to identify the important prognostic parameters that affect overall response to treatment...
  45. doi request reprint A randomized, double-blind comparison of the total dose of 1.0% lidocaine with 1:100,000 epinephrine versus 0.5% lidocaine with 1:200,000 epinephrine required for effective local anesthesia during Mohs micrographic surgery for skin cancers
    Pamela A Morganroth
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Am Acad Dermatol 60:444-52. 2009
    ..We sought to compare total lidocaine dose and patient comfort when using 1.0% lidocaine with 1:100,000 epinephrine versus 0.5% lidocaine with 1:200,000 epinephrine during Mohs micrographic surgery...
  46. doi request reprint Patient-reported outcomes and health-care resource utilization in patients with psoriasis treated with etanercept: continuous versus interrupted treatment
    Joel M Gelfand
    Department of Dermatology and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA
    Value Health 11:400-7. 2008
    ..The objective of this analysis was to assess patient-reported outcomes (PROs) and health-care resource utilization (HRU) data from the EASE study...
  47. pmc Psoriasis and cardiovascular risk: strength in numbers
    Joel M Gelfand
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Invest Dermatol 130:919-22. 2010
    ..This negative result should be interpreted in light of the study's limitations, the complex relationship among levels of psoriasis severity, patient age, and cardiovascular (CV) risk, and the context of the rapidly growing literature...
  48. pmc A prospective clinical trial of open-label etanercept for the treatment of hidradenitis suppurativa
    Robert A Lee
    Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Am Acad Dermatol 60:565-73. 2009
    ..Medical therapies for hidradenitis suppurativa (HS) are often ineffective. Tumor necrosis factor-alpha inhibitors may be a potential treatment for patients with moderate to severe HS...
  49. pmc Synergistic enhancement of cellular immune responses by the novel Toll receptor 7/8 agonist 3M-007 and interferon-γ: implications for therapy of cutaneous T-cell lymphoma
    Maria Wysocka
    Department of Dermatology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Leuk Lymphoma 52:1970-9. 2011
    ..These results further support our hypothesis that combinations of biological modifiers activating different arms of the immune system may provide significant therapeutic benefits for patients with advanced CTCL...
  50. ncbi request reprint Surrogate end points for the treatment of diabetic neuropathic foot ulcers
    David J Margolis
    Department of Dermatology and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Diabetes Care 26:1696-700. 2003
    ....
  51. doi request reprint High prevalence of aquagenic wrinkling of the palms in patients with cystic fibrosis and association with measurable increases in transepidermal water loss
    Lisa M Arkin
    Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Pediatr Dermatol 29:560-6. 2012
    ..Aquagenic wrinkling of the palms is prevalent in children with CF and is associated with increased TEWL...
  52. pmc Assessing long-term drug safety: lessons (re) learned from raptiva
    Nicole M Seminara
    Department of Dermatology, University of Pennsylvania, Philadelphia, PA, USA
    Semin Cutan Med Surg 29:16-9. 2010
    ..Patients and clinicians need to be aware of the relative completeness and limitations of existing safety data of a drug when selecting a treatment...
  53. doi request reprint Update on the epidemiology and systemic treatment of psoriasis
    Shanu Kohli Kurd
    Jefferson Medical College, Philadelphia, PA, USA
    Expert Rev Clin Immunol 3:171-85. 2007
    ..In this article, we focus on recent developments in the epidemiology and systemic treatment of psoriasis...
  54. pmc Psoriasis and metabolic disease: epidemiology and pathophysiology
    Rahat S Azfar
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Curr Opin Rheumatol 20:416-22. 2008
    ..Increasingly, epidemiological studies are establishing the directionality of these associations and psoriasis' role as an independent risk factor in developing these outcomes...
  55. ncbi request reprint Determinants of quality of life in patients with psoriasis: a study from the US population
    Joel M Gelfand
    Department of Dermatology and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, USA
    J Am Acad Dermatol 51:704-8. 2004
    ..Psoriasis is a common disease with substantial effects on quality of life. Few quality of life studies have been performed in psoriasis patients from the general US population...
  56. ncbi request reprint Increased risk for demyelinating diseases in patients with inflammatory bowel disease
    Gauree Gupta
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6021, USA
    Gastroenterology 129:819-26. 2005
    ..However, the underlying relationship between IBD and these neurologic conditions has not been established...
  57. ncbi request reprint The epidemiology of sunburn in the US population in 2003
    Tamu T Brown
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Am Acad Dermatol 55:577-83. 2006
    ..Sunburn is a major preventable risk factor for skin cancer...
  58. ncbi request reprint Epstein-Barr virus and human herpesvirus type 6 infection in patients with psoriasis
    Andrea L Neimann
    Department of Dermatology, University of Pennsylvania, 3600 Spruce Street, 2 Maloney Building, Philadelphia, PA 19104, USA
    Eur J Dermatol 16:548-52. 2006
    ..11). The results of this study suggest that neither severe psoriasis alone, nor in combination with immunosuppressive therapy, is associated with an increase in Epstein-Barr virus or human herpesvirus 6 replication in white blood cells...
  59. pmc Psoriasis in the US Medicare Population: Prevalence, Treatment, and Factors Associated with Biologic Use
    Junko Takeshita
    Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA
    J Invest Dermatol 135:2955-63. 2015
    ..16-0.60). This analysis identified potential financial and racial barriers to receipt of biologic therapies and underscores the need for additional studies to further define the epidemiology and treatment of psoriasis among the elderly. ..
  60. ncbi request reprint Lymphoma rates are low but increased in patients with psoriasis: results from a population-based cohort study in the United Kingdom
    Joel M Gelfand
    Department of Dermatology and the Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadephia 19104, USA
    Arch Dermatol 139:1425-9. 2003
    ..To determine if the rate of lymphoma in patients with a history of psoriasis is different from the rate of lymphoma in patients without psoriasis...
  61. ncbi request reprint Synthetic imidazoquinolines potently and broadly activate the cellular immune response of patients with cutaneous T-cell lymphoma: synergy with interferon-gamma enhances production of interleukin-12
    Maria Wysocka
    Department of Dermatology, University of Pennsylvania, PA 19104, USA
    Clin Lymphoma Myeloma 7:524-34. 2007
    ....
  62. ncbi request reprint Srcasm overexpression in psoriasis-insights into pathogenesis
    Melissa Pulitzer
    Department of Dermatology, University of Pennsylvania Medical School, Philadelphia, PA, USA
    J Cutan Pathol 34:160-5. 2007
    ..In this study, the levels of Srcasm mRNA and protein are characterized, and the relationship of these experimental observations to the psoriasis pathogenesis is discussed...