R Garay

Summary

Publications

  1. ncbi Vascular permeabilization by intravenous arachidonate in the rat peritoneal cavity: antagonism by ethamsylate
    Patrick Hannaert
    INSERM U400, Faculte de Medecine, 8 rue du General Sarrail, Cedex 94010, Creteil, France
    Eur J Pharmacol 466:207-12. 2003
  2. ncbi Therapeutic efficacy and mechanism of action of ethamsylate, a long-standing hemostatic agent
    Ricardo P Garay
    Equipe d Accueil EA2381, LPTIM, Case 7124, Tour 54 5, Universite Paris 7, Paris, France
    Am J Ther 13:236-47. 2006
  3. ncbi Mechanisms of vasomotor rhinitis
    R Garay
    INSERM U400, Faculté de Médecine de Créteil, France
    Allergy 59:4-9; discussion 9-10. 2004
  4. ncbi Calcium dobesilate in the treatment of diabetic retinopathy
    Ricardo P Garay
    Equipe d Accueil EA2381, Laboratoire Pharmacologie Transports Ioniques Membranaires, Universite Paris 7, Paris, France
    Treat Endocrinol 4:221-32. 2005
  5. ncbi Reduction of retinal albumin leakage by the antioxidant calcium dobesilate in streptozotocin-diabetic rats
    Rossella Rota
    Children s Hospital Bambino Gesu, IRCCS, Rome, Italy
    Eur J Pharmacol 495:217-24. 2004
  6. ncbi The hemostatic agent ethamsylate enhances P-selectin membrane expression in human platelets and cultured endothelial cells
    Miriam Alvarez-Guerra
    INSERM U400, Faculte de Medecine, 8 rue du General Sarrail, 94010 Creteil Cedex, France
    Thromb Res 107:329-35. 2002
  7. ncbi Vascular permeabilization by intravenous arachidonate in the rat peritoneal cavity: antagonism by antioxidants
    Miriam Alvarez-Guerra
    INSERM U400, Faculte de Medecine, 8 rue du General Sarrail, 94010 Cedex, Creteil, France
    Eur J Pharmacol 466:199-205. 2003
  8. ncbi The hemostatic agent ethamsylate promotes platelet/leukocyte aggregate formation in a model of vascular injury
    Maria Rosa Hernandez
    Department of Hemotherapy and Hemostasis, Hospital Clinic, Barcelone, Spain
    Fundam Clin Pharmacol 18:423-30. 2004
  9. ncbi Inhibition of choroidal angiogenesis by calcium dobesilate in normal Wistar and diabetic GK rats
    Stéphane Lameynardie
    Laboratoire de Nutrition Humaine et Athérogenèse, Institut Universitaire de Recherche Clinique, Montpellier, France
    Eur J Pharmacol 510:149-56. 2005

Collaborators

  • Carlo Chiavaroli
  • Patrick Hannaert
  • Miriam Alvarez-Guerra
  • Maria Rosa Hernandez
  • Stéphane Lameynardie
  • Rossella Rota
  • Gines Escolar
  • Hamida Hider
  • Pierre Travo
  • Nuria Pares-Herbute

Detail Information

Publications9

  1. ncbi Vascular permeabilization by intravenous arachidonate in the rat peritoneal cavity: antagonism by ethamsylate
    Patrick Hannaert
    INSERM U400, Faculte de Medecine, 8 rue du General Sarrail, Cedex 94010, Creteil, France
    Eur J Pharmacol 466:207-12. 2003
    ..Such a mechanism can explain previous observations that ethamsylate inhibits carrageenan-induced rat paw edema. Whether it also participates in the hemostatic action of ethamsylate deserves further investigation...
  2. ncbi Therapeutic efficacy and mechanism of action of ethamsylate, a long-standing hemostatic agent
    Ricardo P Garay
    Equipe d Accueil EA2381, LPTIM, Case 7124, Tour 54 5, Universite Paris 7, Paris, France
    Am J Ther 13:236-47. 2006
    ..It is suggested that the place of ethamsylate as a hemostatic agent is that of a mild but well-tolerated drug, particularly useful in dysfunctional uterine bleeding when contraception is not needed...
  3. ncbi Mechanisms of vasomotor rhinitis
    R Garay
    INSERM U400, Faculté de Médecine de Créteil, France
    Allergy 59:4-9; discussion 9-10. 2004
    ..Indirect evidence suggests that C-fibres may also play an important role in the pathophysiology of idiopathic rhinitis...
  4. ncbi Calcium dobesilate in the treatment of diabetic retinopathy
    Ricardo P Garay
    Equipe d Accueil EA2381, Laboratoire Pharmacologie Transports Ioniques Membranaires, Universite Paris 7, Paris, France
    Treat Endocrinol 4:221-32. 2005
    ..In addition, it improves diabetic endothelial dysfunction, reduces apoptosis, and slows vascular cell proliferation...
  5. ncbi Reduction of retinal albumin leakage by the antioxidant calcium dobesilate in streptozotocin-diabetic rats
    Rossella Rota
    Children s Hospital Bambino Gesu, IRCCS, Rome, Italy
    Eur J Pharmacol 495:217-24. 2004
    ..These results strongly suggest that calcium dobesilate stabilizes blood-retinal barrier in diabetic retinopathy via an in situ antioxidant action. Further studies in patients are required to confirm such view...
  6. ncbi The hemostatic agent ethamsylate enhances P-selectin membrane expression in human platelets and cultured endothelial cells
    Miriam Alvarez-Guerra
    INSERM U400, Faculte de Medecine, 8 rue du General Sarrail, 94010 Creteil Cedex, France
    Thromb Res 107:329-35. 2002
    ..These results support the view that ethamsylate acts on the first step of hemostasis, by improving platelet adhesiveness and restoring capillary resistance...
  7. ncbi Vascular permeabilization by intravenous arachidonate in the rat peritoneal cavity: antagonism by antioxidants
    Miriam Alvarez-Guerra
    INSERM U400, Faculte de Medecine, 8 rue du General Sarrail, 94010 Cedex, Creteil, France
    Eur J Pharmacol 466:199-205. 2003
    ..This rat peritoneal model can be used to evaluate the in vivo antinflammatory potential of antioxidant drugs...
  8. ncbi The hemostatic agent ethamsylate promotes platelet/leukocyte aggregate formation in a model of vascular injury
    Maria Rosa Hernandez
    Department of Hemotherapy and Hemostasis, Hospital Clinic, Barcelone, Spain
    Fundam Clin Pharmacol 18:423-30. 2004
    ..Res. (2002)107:329-335] confirms and extends the view that ethamsylate acts on the first step of hemostasis, by improving platelet homo- and heterotypic adhesiveness...
  9. ncbi Inhibition of choroidal angiogenesis by calcium dobesilate in normal Wistar and diabetic GK rats
    Stéphane Lameynardie
    Laboratoire de Nutrition Humaine et Athérogenèse, Institut Universitaire de Recherche Clinique, Montpellier, France
    Eur J Pharmacol 510:149-56. 2005
    ..This effect may be due, at least in part, to inhibition of VEGF production. Antiangiogenesis by calcium dobesilate can be involved in its therapeutic benefit in diabetic retinopathy...