G Gallagher

Summary

Publications

  1. ncbi request reprint Cloning, expression and initial characterization of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10)
    G Gallagher
    University of Glasgow Department of Surgery, Queen Elizabeth Building, Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow G312ER, Scotland, UK
    Genes Immun 1:442-50. 2000
  2. ncbi request reprint Structural characterisation of the distal 5' flanking region of the human interleukin-10 gene
    D Kube
    Eberhard Karls Universität Universitätsklinikum, Institut für Tropenmedizin Sektion Humanparasitologie, D 72074 Tubingen, Germany
    Genes Immun 2:181-90. 2001
  3. ncbi request reprint A second polymorphic dinucleotide repeat in the 5' flanking region of the human IL10 gene
    J Eskdale
    University of Glasgow Department of Surgery, Queen Elizabeth Building, Glasgow Royal Infirmary, Glasgow G31 2ER, Scotland
    Immunogenetics 45:82-3. 1996
  4. ncbi request reprint Allele associations reveal four prominent haplotypes at the human interleukin-6 (IL-6) locus
    N Jordanides
    University of Glasgow Department of Surgery, Queen Elizabeth Building, Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow G31 2ER, Scotland
    Genes Immun 1:451-5. 2000
  5. pmc Interleukin 10 secretion in relation to human IL-10 locus haplotypes
    J Eskdale
    University of Glasgow Department of Surgery, Queen Elizabeth Building, Glasgow Royal Infirmary Glasgow G31 2ER, Scotland
    Proc Natl Acad Sci U S A 95:9465-70. 1998
  6. ncbi request reprint A polymorphic dinucleotide repeat in the human IL-10 promoter
    J Eskdale
    University of Glasgow Department of Surgery, Queen Elizabeth Building, Glasgow Royal Infirmary, Glasgow G31 2ER, Scotland
    Immunogenetics 42:444-5. 1995
  7. ncbi request reprint Mapping of the human IL10 gene and further characterization of the 5' flanking sequence
    J Eskdale
    University of Glasgow Department of Surgery, Queen Elizabeth Building, Glasgow Royal Infirmary, Glasgow G31 2ER, Scotland
    Immunogenetics 46:120-8. 1997
  8. ncbi request reprint Interleukin-10 microsatellite polymorphisms and IL-10 locus alleles in rheumatoid arthritis susceptibility
    J Eskdale
    Lancet 352:1282-3. 1998
  9. ncbi request reprint Association between polymorphisms at the human IL-10 locus and systemic lupus erythematosus
    J Eskdale
    Immunology Research Group, University of Glasgow Department of Surgery, United Kingdom
    Tissue Antigens 49:635-9. 1997
  10. ncbi request reprint Interferon lambda-1 (IFN-lambda1/IL-29) induces ELR(-) CXC chemokine mRNA in human peripheral blood mononuclear cells, in an IFN-gamma-independent manner
    V Pekarek
    HUMIGEN, The Institute for Genetic Immunology, Hamilton, NJ 08690 3303, USA
    Genes Immun 8:177-80. 2007

Collaborators

  • R P Donnelly
  • H Rieth
  • S V Kotenko
  • R G Westendorp
  • J Eskdale
  • W J Jordan
  • V Pekarek
  • D Kube
  • S Srinivas
  • M Rodia
  • N Haukim
  • T Huizinga
  • J McNicholl
  • N Jordanides
  • M Boniotto
  • D Kelner
  • D Kellner
  • P Wordsworth
  • M Field
  • L J Keen
  • F Pociot
  • C Hardt
  • M F McDermott
  • A J P Smith
  • R Kimberly
  • J L Bidwell
  • S D'Alfonso
  • J Oksenberg
  • P G Kremsner
  • R Stuart
  • T W Huizinga
  • B Jonas
  • V Keijsers
  • C L Verweij
  • S Bowman
  • H Tesch

Detail Information

Publications13

  1. ncbi request reprint Cloning, expression and initial characterization of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10)
    G Gallagher
    University of Glasgow Department of Surgery, Queen Elizabeth Building, Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow G312ER, Scotland, UK
    Genes Immun 1:442-50. 2000
    ..IL-19 does not bind or signal through the canonical IL-10 receptor complex, suggesting existence of an IL-19 specific receptor complex, the identity of which remains to be discovered...
  2. ncbi request reprint Structural characterisation of the distal 5' flanking region of the human interleukin-10 gene
    D Kube
    Eberhard Karls Universität Universitätsklinikum, Institut für Tropenmedizin Sektion Humanparasitologie, D 72074 Tubingen, Germany
    Genes Immun 2:181-90. 2001
    ..The SNPs at -8571 C/T and -8531 G/A are contained within an Alu-repeat. These data should further the understanding of how the IL-10 gene is controlled in man and how its function may vary between individuals...
  3. ncbi request reprint A second polymorphic dinucleotide repeat in the 5' flanking region of the human IL10 gene
    J Eskdale
    University of Glasgow Department of Surgery, Queen Elizabeth Building, Glasgow Royal Infirmary, Glasgow G31 2ER, Scotland
    Immunogenetics 45:82-3. 1996
  4. ncbi request reprint Allele associations reveal four prominent haplotypes at the human interleukin-6 (IL-6) locus
    N Jordanides
    University of Glasgow Department of Surgery, Queen Elizabeth Building, Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow G31 2ER, Scotland
    Genes Immun 1:451-5. 2000
    ..We propose that these haplotypes be identified as IL6.0103, IL6.0204, IL6.0207 and IL6.0307, in recognition of their frequency in this population and the alleles that they contain...
  5. pmc Interleukin 10 secretion in relation to human IL-10 locus haplotypes
    J Eskdale
    University of Glasgow Department of Surgery, Queen Elizabeth Building, Glasgow Royal Infirmary Glasgow G31 2ER, Scotland
    Proc Natl Acad Sci U S A 95:9465-70. 1998
    ..R3/IL10.G7 was associated with lowest IL-10 secretion. These data demonstrate that the ability to secrete IL-10 can vary in man according to the genetic composition of the IL-10 locus...
  6. ncbi request reprint A polymorphic dinucleotide repeat in the human IL-10 promoter
    J Eskdale
    University of Glasgow Department of Surgery, Queen Elizabeth Building, Glasgow Royal Infirmary, Glasgow G31 2ER, Scotland
    Immunogenetics 42:444-5. 1995
  7. ncbi request reprint Mapping of the human IL10 gene and further characterization of the 5' flanking sequence
    J Eskdale
    University of Glasgow Department of Surgery, Queen Elizabeth Building, Glasgow Royal Infirmary, Glasgow G31 2ER, Scotland
    Immunogenetics 46:120-8. 1997
    ..These data should further the understanding of how the IL10 gene is controlled in humans and how its function may vary between individuals...
  8. ncbi request reprint Interleukin-10 microsatellite polymorphisms and IL-10 locus alleles in rheumatoid arthritis susceptibility
    J Eskdale
    Lancet 352:1282-3. 1998
  9. ncbi request reprint Association between polymorphisms at the human IL-10 locus and systemic lupus erythematosus
    J Eskdale
    Immunology Research Group, University of Glasgow Department of Surgery, United Kingdom
    Tissue Antigens 49:635-9. 1997
    ..Although the moderate sample size described in this study requires that the results be interpreted carefully, they provide an interesting and useful framework for future study...
  10. ncbi request reprint Interferon lambda-1 (IFN-lambda1/IL-29) induces ELR(-) CXC chemokine mRNA in human peripheral blood mononuclear cells, in an IFN-gamma-independent manner
    V Pekarek
    HUMIGEN, The Institute for Genetic Immunology, Hamilton, NJ 08690 3303, USA
    Genes Immun 8:177-80. 2007
    ..Overall the action of IFN-lambda1 was similar to that previously reported for IFN-gamma and may invite more detailed investigation of the role of IFN-lambda1 at the innate/adaptive interface...
  11. ncbi request reprint Cytokine gene polymorphism in human disease: on-line databases, supplement 2
    N Haukim
    Department of Pathology and Microbiology, University of Bristol, Homoeopathic Hospital Site, Cotham, Bristol BS6 6JU, UK
    Genes Immun 3:313-30. 2002
  12. ncbi request reprint Modulation of the human cytokine response by interferon lambda-1 (IFN-lambda1/IL-29)
    W J Jordan
    Department of Oral Biology, New Jersey Dental School, Newark, NJ, USA
    Genes Immun 8:13-20. 2007
    ....
  13. ncbi request reprint Human interferon lambda-1 (IFN-lambda1/IL-29) modulates the Th1/Th2 response
    W J Jordan
    Department of Oral Biology, New Jersey Dental School, Newark, NJ, USA
    Genes Immun 8:254-61. 2007
    ..These functions were independent of IL-10. Our data support a hitherto unsuspected role for IFN-lambda1 in modulating the development of Th1 and Th2 cells, with an apparent emphasis on the diminution of IL-13 secretion...