Claire Wilhelm

Summary

Country: France

Publications

  1. ncbi request reprint Out-of-equilibrium microrheology inside living cells
    Claire Wilhelm
    Laboratoire Matiere et Systemes Complexes MSC, UMR 7057, CNRS and University Paris Diderot, Paris, France
    Phys Rev Lett 101:028101. 2008
  2. ncbi request reprint Acto-myosin cytoskeleton dependent viscosity and shear-thinning behavior of the amoeba cytoplasm
    Sabrina Marion
    Unité de Biologie Cellulaire du Parasitisme, INSERM U389, Institut Pasteur, Paris, France
    Eur Biophys J 34:262-72. 2005
  3. ncbi request reprint Continuous sorting of magnetic cells via on-chip free-flow magnetophoresis
    Nicole Pamme
    National Institute for Materials Science NIMS, International Centre for Young Scientists ICYS, 1 1 Namiki, Tsukuba, Ibaraki 305 0044, Japan
    Lab Chip 6:974-80. 2006
  4. ncbi request reprint Tumour cell toxicity of intracellular hyperthermia mediated by magnetic nanoparticles
    Claire Wilhelm
    Laboratoire Matière et Systèmes Complexes, CNRS UMR 7057, Universite Paris Diderot, Paris, France
    J Nanosci Nanotechnol 7:2933-7. 2007
  5. doi request reprint Can magneto-plasmonic nanohybrids efficiently combine photothermia with magnetic hyperthermia?
    Ana Espinosa
    Laboratoire Matiere et Systemes Complexes MSC, UMR 7057, CNRS and Université Paris Diderot, 75205 Paris Cedex 13, France
    Nanoscale 7:18872-7. 2015
  6. doi request reprint Magnetic engineering of stable rod-shaped stem cell aggregates: circumventing the pitfall of self-bending
    V Du
    Laboratoire Matière et Systèmes Complexes, CNRS UMR 7057, Universite Paris 7, France
    Integr Biol (Camb) 7:170-7. 2015
  7. doi request reprint Cell-derived vesicles as a bioplatform for the encapsulation of theranostic nanomaterials
    Amanda K Andriola Silva
    Laboratoire Matière et Systèmes Complexes, UMR 7057, CNRS and Université Paris Diderot, 10 rue Alice Domon et Leonie Duquet, 75205 Paris Cedex 13, France
    Nanoscale 5:11374-84. 2013
  8. doi request reprint [Magnetic nanoparticles as tools for cell therapy]
    Claire Wilhelm
    Laboratoire Matière et Systèmes Complexes, CNRS Universite Paris Diderot, 75205 Paris Cedex 13, France
    Biol Aujourdhui 206:273-84. 2012
  9. doi request reprint Universal cell labelling with anionic magnetic nanoparticles
    Claire Wilhelm
    Laboratoire Matiere et Systemes Complexes MSC, UMR 7057 CNRS et Université Paris Diderot, Paris, France
    Biomaterials 29:3161-74. 2008
  10. doi request reprint Intracellular trafficking of magnetic nanoparticles to design multifunctional biovesicles
    Claire Wilhelm
    Laboratoire Matière et Systèmes Complexes MSC Université Denis Diderot Paris 7 CNRS UMR 7057, Batiment Condorcet, CC 7056 10 rue Alice Domon et Léonie Duquet, 75205 Paris cedex, France
    Small 4:577-82. 2008

Collaborators

Detail Information

Publications69

  1. ncbi request reprint Out-of-equilibrium microrheology inside living cells
    Claire Wilhelm
    Laboratoire Matiere et Systemes Complexes MSC, UMR 7057, CNRS and University Paris Diderot, Paris, France
    Phys Rev Lett 101:028101. 2008
    ..The combined use of passive microrheology allows one to derive the power spectrum of active forces acting on intracellular phagosomes and to test the validity of the fluctuation-dissipation theorem inside living cells...
  2. ncbi request reprint Acto-myosin cytoskeleton dependent viscosity and shear-thinning behavior of the amoeba cytoplasm
    Sabrina Marion
    Unité de Biologie Cellulaire du Parasitisme, INSERM U389, Institut Pasteur, Paris, France
    Eur Biophys J 34:262-72. 2005
    ..In this study, we also investigated the role of the actin-based motor myosin II and concluded that myosin II stiffens the F-actin gel in living parasites likely by its cross-linking activity...
  3. ncbi request reprint Continuous sorting of magnetic cells via on-chip free-flow magnetophoresis
    Nicole Pamme
    National Institute for Materials Science NIMS, International Centre for Young Scientists ICYS, 1 1 Namiki, Tsukuba, Ibaraki 305 0044, Japan
    Lab Chip 6:974-80. 2006
    ..The experimentally observed deflection matched well with calculations. Furthermore, the separation of magnetic and non-magnetic cells was demonstrated using the same microfluidic device...
  4. ncbi request reprint Tumour cell toxicity of intracellular hyperthermia mediated by magnetic nanoparticles
    Claire Wilhelm
    Laboratoire Matière et Systèmes Complexes, CNRS UMR 7057, Universite Paris Diderot, Paris, France
    J Nanosci Nanotechnol 7:2933-7. 2007
    ..These findings pave the way for an efficient cell killing mediated by intracellular magnetic hyperthermia...
  5. doi request reprint Can magneto-plasmonic nanohybrids efficiently combine photothermia with magnetic hyperthermia?
    Ana Espinosa
    Laboratoire Matiere et Systemes Complexes MSC, UMR 7057, CNRS and Université Paris Diderot, 75205 Paris Cedex 13, France
    Nanoscale 7:18872-7. 2015
    ....
  6. doi request reprint Magnetic engineering of stable rod-shaped stem cell aggregates: circumventing the pitfall of self-bending
    V Du
    Laboratoire Matière et Systèmes Complexes, CNRS UMR 7057, Universite Paris 7, France
    Integr Biol (Camb) 7:170-7. 2015
    ..Optimisation of the intra-tissular magnetic forces successfully hindered the transition, in order to produce stable rod-shaped stem cells aggregates. ..
  7. doi request reprint Cell-derived vesicles as a bioplatform for the encapsulation of theranostic nanomaterials
    Amanda K Andriola Silva
    Laboratoire Matière et Systèmes Complexes, UMR 7057, CNRS and Université Paris Diderot, 10 rue Alice Domon et Leonie Duquet, 75205 Paris Cedex 13, France
    Nanoscale 5:11374-84. 2013
    ..The resulting assets for targeting, imaging and therapy converge for the outline of a new generation of nanosystems merging versatility and multifunctionality into a bio-camouflaged and bio-inspired approach. ..
  8. doi request reprint [Magnetic nanoparticles as tools for cell therapy]
    Claire Wilhelm
    Laboratoire Matière et Systèmes Complexes, CNRS Universite Paris Diderot, 75205 Paris Cedex 13, France
    Biol Aujourdhui 206:273-84. 2012
    ..Owing to the clinical approval of iron-oxide nanoparticles as MRI contrast agent, there is no major obstacle in the translation to human clinics of the magnetic methods summarized in this paper...
  9. doi request reprint Universal cell labelling with anionic magnetic nanoparticles
    Claire Wilhelm
    Laboratoire Matiere et Systemes Complexes MSC, UMR 7057 CNRS et Université Paris Diderot, Paris, France
    Biomaterials 29:3161-74. 2008
    ..We also show that the same label provides sufficient magnetization for MRI detection and distal manipulation...
  10. doi request reprint Intracellular trafficking of magnetic nanoparticles to design multifunctional biovesicles
    Claire Wilhelm
    Laboratoire Matière et Systèmes Complexes MSC Université Denis Diderot Paris 7 CNRS UMR 7057, Batiment Condorcet, CC 7056 10 rue Alice Domon et Léonie Duquet, 75205 Paris cedex, France
    Small 4:577-82. 2008
  11. ncbi request reprint Magnetic control of Dictyostelium aggregation
    C Wilhelm
    Laboratoire Matière et Systèmes Complexes, CNRS UMR 7057 Université Paris 7, Paris, France
    Phys Rev E Stat Nonlin Soft Matter Phys 75:041906. 2007
    ..We therefore underline the interplay between external mechanical forces and morphogenesis. This magnetic assay will open new possibilities in the study of morphogenesis in Dictyostelium...
  12. ncbi request reprint Magnetic control of vascular network formation with magnetically labeled endothelial progenitor cells
    C Wilhelm
    Laboratoire Matière et Systèmes Complexes, CNRS UMR 7057, Universite Paris 7, Paris, France
    Biomaterials 28:3797-806. 2007
    ..Magnetic cell targeting opens up new possibilities for vascular tissue engineering and for delivering localized cell-based therapies...
  13. doi request reprint Endothelial cell-derived microparticles loaded with iron oxide nanoparticles: feasibility of MR imaging monitoring in mice
    Achraf Al Faraj
    Laboratoire Matière et Systèmes Complexes, Universite Paris Diderot Paris 7, CNRS UMR 7057, Paris, France
    Radiology 263:169-78. 2012
    ..To assess the feasibility of loading iron oxide nanoparticles in endothelial microparticles (EMPs), thereby enabling their noninvasive monitoring with magnetic resonance (MR) imaging in mice...
  14. doi request reprint Biodegradation of iron oxide nanocubes: high-resolution in situ monitoring
    Lenaic Lartigue
    Laboratoire Matières et Systèmes Complexes, UMR 7057, and Laboratoire Matériaux et Phénomènes Quantiques, UMR 7162, CNRS Universite Paris Diderot, 10 rue Alice Domon et Leonie Duquet, F 75205 Paris Cedex 13, France
    ACS Nano 7:3939-52. 2013
    ..Our approach reduces the gap between in situ nanoscale observations in mimicking biological environments and in vivo real tracking of nanoparticle fate...
  15. doi request reprint Magnetophoresis at the nanoscale: tracking the magnetic targeting efficiency of nanovectors
    Amanda K Andriola Silva
    Laboratoire Matière and Systèmes Complexes, UMR 7057, CNRS and Université Paris Diderot, 10 rue Alice Domon and Léonie Duquet, 75205 Paris Cedex 13, France
    Nanomedicine (Lond) 7:1713-27. 2012
    ..We propose herein a miniaturized approach for appraising magnetophoretic mobility at the nanoscale...
  16. doi request reprint Cellular transfer of magnetic nanoparticles via cell microvesicles: impact on cell tracking by magnetic resonance imaging
    Amanda K Andriola Silva
    Laboratoire Matière et Systèmes Complexes, UMR 7057, CNRS Universite Paris Diderot, Sorbonne Paris Cité, 75205 Paris Cedex 13, France
    Pharm Res 29:1392-403. 2012
    ..We investigated a mechanism of intercellular cross-transfer of magnetic nanoparticles to different types of recipient cells via cell microvesicles released under cellular stress...
  17. doi request reprint Design of biomimetic vascular grafts with magnetic endothelial patterning
    Delphine Fayol
    Laboratoire Matiere et Systemes Complexes MSC, UMR 7057 CNRS and Université Paris Diderot, Paris, France
    Cell Transplant 22:2105-18. 2013
    ..In particular, the observation of different cell organizations in a vascular scaffold within the range of resolution of single cells by 4.7 T MRI is reported. ..
  18. doi request reprint The MRI assessment of intraurethrally--delivered muscle precursor cells using anionic magnetic nanoparticles
    Charlotte Rivière
    Laboratoire Matière et Systèmes Complexes, UMR CNRS 7057, University Paris Diderot, Batiment Condorcet, Case 7056, F 75205 Paris Cedex 13, France
    Biomaterials 30:6920-8. 2009
    ..AMNP labeling was thus useful for locating myofiber implant autografts in vivo and for ex vivo monitoring of the biology of this cell transfer method...
  19. doi request reprint Cooperative organization in iron oxide multi-core nanoparticles potentiates their efficiency as heating mediators and MRI contrast agents
    Lenaic Lartigue
    Laboratoire Matières et Systèmes Complexes, UMR 7057 CNRS Université Paris Diderot, 10 rue Alice Domon et Leonie Duquet, 75013 Paris, France
    ACS Nano 6:10935-49. 2012
    ....
  20. doi request reprint Magnetic and photoresponsive theranosomes: translating cell-released vesicles into smart nanovectors for cancer therapy
    Amanda K A Silva
    Laboratoire Matière et Systèmes Complexes, UMR 7057, CNRS and Université Paris Diderot, 10 rue Alice Domon et Leonie Duquet, 75205 Paris Cedex 13, France
    ACS Nano 7:4954-66. 2013
    ..This study reports the first success in translating a cell communication mediator into a smart theranostic nanovector. ..
  21. doi request reprint Nanomagnetic sensing of blood plasma protein interactions with iron oxide nanoparticles: impact on macrophage uptake
    Lenaic Lartigue
    Laboratoire Matiere et Systemes Complexes MSC, UMR 7057 CNRS Université Paris Diderot, PRES Sorbonne Paris Cité, 75205 Paris Cedex 13, France
    ACS Nano 6:2665-78. 2012
    ....
  22. doi request reprint Nanomagnetism reveals the intracellular clustering of iron oxide nanoparticles in the organism
    Michael Levy
    Laboratoire Matière et Systèmes Complexes, UMR 7057 CNRS Université Paris Diderot, 10 rue Alice Domon et Leonie Duquet, 75013 Paris, France
    Nanoscale 3:4402-10. 2011
    ..Nanomagnetism probes the intracellular clustering of iron-oxide NPs and sheds light on the impact of cellular metabolism on their magnetic responsivity...
  23. doi request reprint In vivo single cell detection of tumor-infiltrating lymphocytes with a clinical 1.5 Tesla MRI system
    Pierre Smirnov
    Laboratoire Matière et Systèmes Complexes, UMR 7057 CNRS, Universite Paris 7 Denis Diderot, Paris, France
    Magn Reson Med 60:1292-7. 2008
    ..2 pg of iron per cell. The same imaging protocol was used in vivo to monitor infiltration of ovalbumin-expressing tumors by transferred OVA antigen-specific cytotoxic lymphocytes with low iron load...
  24. ncbi request reprint Size-sorted anionic iron oxide nanomagnets as colloidal mediators for magnetic hyperthermia
    Jean Paul Fortin
    Laboratoire Matière et Systèmes Complexes, UMR CNRS 7057, University Paris 7, 140 rue de Lourmel, 75015 Paris, France
    J Am Chem Soc 129:2628-35. 2007
    ..8 kA/m). This comprehensive parametric study provides the groundwork for the use of anionic colloidal nanocrystals to generate magnetically induced hyperthermia in various media, including complex systems and biological materials...
  25. ncbi request reprint Magnetic targeting of nanometric magnetic fluid loaded liposomes to specific brain intravascular areas: a dynamic imaging study in mice
    Charlotte Rivière
    Laboratoire Matière et Systèmes Complexes, CNRS UMR 7057, Universite Paris 7 Denis Diderot, 140, rue de Lourmel, 75015 Paris, France
    Radiology 244:439-48. 2007
    ..To prospectively determine, by using dynamic imaging, whether a magnet placed over a specific area of the mouse brain could target systemically administered rhodamine-labeled magnetic fluid-loaded liposomes (MFLs) to that brain region...
  26. doi request reprint Can magnetic targeting of magnetically labeled circulating cells optimize intramyocardial cell retention?
    Aurélie Chaudeurge
    INSERM U633, Laboratory of Surgical Research, Paris, France
    Cell Transplant 21:679-91. 2012
    ..Magnetic targeting has the potential to enhance myocardial retention of intravascularly delivered endothelial progenitor cells...
  27. doi request reprint How cellular processing of superparamagnetic nanoparticles affects their magnetic behavior and NMR relaxivity
    Michael Levy
    Laboratoire Matière et Systèmes Complexes, UMR CNRS Université Paris Diderot, France
    Contrast Media Mol Imaging 7:373-83. 2012
    ..This study is the first attempt to link up magnetic properties and NMR characterization of iron oxide nanoparticles before and after their cell processing...
  28. doi request reprint Magnetic tagging of cell-derived microparticles: new prospects for imaging and manipulation of these mediators of biological information
    Nidhi Vats
    Laboratoire Matière et Systèmes Complexes, UMR 7057, CNRS and Université Paris Diderot, 10 rue Alice Domon et Leonie Duquet, 75205 Paris Cedex 13, France
    Nanomedicine (Lond) 5:727-38. 2010
    ..We propose the tagging of MPs with magnetic nanoparticles as a new approach allowing imaging, manipulation and targeting of cell-derived MPs...
  29. doi request reprint Cell sorting by endocytotic capacity in a microfluidic magnetophoresis device
    Damien Robert
    Laboratoire Matière et Systèmes Complexes, UMR CNRS et Université Paris Diderot, France
    Lab Chip 11:1902-10. 2011
    ..The introduced method constitutes a viable tool for studies of endocytotic capacity and sorting/selection of cells based on this functionality...
  30. doi request reprint Cancer Cell Internalization of Gold Nanostars Impacts Their Photothermal Efficiency In Vitro and In Vivo: Toward a Plasmonic Thermal Fingerprint in Tumoral Environment
    Ana Espinosa
    Laboratoire Matiere et Systemes Complexes MSC, UMR 7057, CNRS and Université Paris Diderot, 75205, Paris Cedex 13, France
    Adv Healthc Mater 5:1040-8. 2016
    ..The plasmonic heating response thus serves as a signature of nanoparticle internalization in cells, bringing the ultimate goal of nanoparticle-mediated photothermal therapy a step closer. ..
  31. doi request reprint Magnetic hyperthermia efficiency in the cellular environment for different nanoparticle designs
    Riccardo Di Corato
    Laboratoire Matière et Systèmes Complexes, UMR 7057, CNRS and Université Paris Diderot, 75205 Paris Cedex 13, France
    Biomaterials 35:6400-11. 2014
    ..The fall in heating correlated with the magnetic characterization of the samples, demonstrating a complete inhibition of the Brownian relaxation in cellular conditions. ..
  32. ncbi request reprint Intracellular heating of living cells through Néel relaxation of magnetic nanoparticles
    Jean Paul Fortin
    CNRS UMR 7057, Universite Paris 7, Paris, France
    Eur Biophys J 37:223-8. 2008
    ..Hence, we are able to derive the best nanoparticle design for a given material with a view to intracellular hyperthermia-based applications...
  33. doi request reprint Heat-generating iron oxide nanocubes: subtle "destructurators" of the tumoral microenvironment
    Jelena Kolosnjaj-Tabi
    Laboratoire Matière et Systèmes Complexes, UMR 7057 CNRS Université Paris Diderot, 10 rue Alice Domon et Leonie Duquet, F 75205 Paris Cedex 13, France
    ACS Nano 8:4268-83. 2014
    ....
  34. doi request reprint High-resolution cellular MRI: gadolinium and iron oxide nanoparticles for in-depth dual-cell imaging of engineered tissue constructs
    Riccardo Di Corato
    Laboratoire Matière et Systèmes Complexes, UMR 7057, CNRS and Université Paris Diderot, France
    ACS Nano 7:7500-12. 2013
    ..In addition, endothelial cells labeled with iron oxide nanoparticles could be remotely manipulated by applying a magnetic field, allowing the creation of vessel substitutes with in-depth detection of individual cellular components. ..
  35. doi request reprint Long term in vivo biotransformation of iron oxide nanoparticles
    Michael Levy
    Laboratoire Matières et Systèmes Complexes MSC, UMR 7057 CNRS Université Paris Diderot, 10 rue Alice Domon et Leonie Duquet, 75205 Paris Cedex 13, France
    Biomaterials 32:3988-99. 2011
    ..A putative mechanism is proposed for the biotransformation of iron-oxide nanoparticles...
  36. doi request reprint Real-time high-resolution magnetic resonance tracking of macrophage subpopulations in a murine inflammation model: a pilot study with a commercially available cryogenic probe
    Achraf Al Faraj
    Laboratoire Matiere et Systemes Complexes MSC, CNRS UMR7057, Universite Paris Diderot, Paris, France
    Contrast Media Mol Imaging 8:193-203. 2013
    ..Coupled to whole body imaging, HR-MRI provides quantitative information on the time course of migration of ex vivo-polarized intravenously injected macrophages...
  37. doi request reprint Managing magnetic nanoparticle aggregation and cellular uptake: a precondition for efficient stem-cell differentiation and MRI tracking
    Delphine Fayol
    Laboratoire Matière et Systèmes Complexes, UMR 7057 CNRS and University Paris Diderot, Paris, France
    Adv Healthc Mater 2:313-25. 2013
    ..Magnetic labeling conditions with perfectly stable nanoparticles-suitable for obtaining differentiation-capable magnetic stem cells for use in cell therapy-are subsequently identified...
  38. doi request reprint Optimizing magnetic nanoparticle design for nanothermotherapy
    Florence Gazeau
    Laboratoire Matiere et Systemes Complexes MSC, UMR 7057 CNRS, Université Paris Diderot Bâtiment Condorcet, Paris Cedex 13, France
    Nanomedicine (Lond) 3:831-44. 2008
    ..Towards therapy, achievements and promises of magnetic nanoparticles for cancer-localized hyperthermia, targeting strategies and multivalent functionalities are exposed...
  39. doi request reprint Duality of Iron Oxide Nanoparticles in Cancer Therapy: Amplification of Heating Efficiency by Magnetic Hyperthermia and Photothermal Bimodal Treatment
    Ana Espinosa
    Laboratoire Matière et Systèmes Complexes, UMR 7057, CNRS and University Paris Diderot, 75205 Paris Cedex 13, France
    ACS Nano 10:2436-46. 2016
    ....
  40. doi request reprint Combining magnetic nanoparticles with cell derived microvesicles for drug loading and targeting
    Amanda K A Silva
    Laboratoire Matière et Systèmes Complexes, UMR 7057, CNRS and Université Paris Diderot, France INSERM, U1148, Cardiovascular Bio engineering, X Bichat Hospital, Université Paris Diderot Paris, France Université Paris 13, Sorbonne Paris Cité, France
    Nanomedicine 11:645-55. 2015
    ..They showed that the microvesicles could be manipulated by magnetic force for targeting and subsequent delivery of the drug payload against cancer cells. This smart method could provide a novel way for future fight against cancer...
  41. doi request reprint Combining magnetic hyperthermia and photodynamic therapy for tumor ablation with photoresponsive magnetic liposomes
    Riccardo Di Corato
    Laboratoire Matière et Systèmes Complexes, UMR 7057, CNRS and University Paris Diderot, 75205 Paris Cedex 13, France
    ACS Nano 9:2904-16. 2015
    ..These liposomes address both therapeutic agents within tumor cells, and the combined PDT/MHT therapy resulted in complete cancer cell death in vitro while total solid-tumor ablation was achieved in an in vivo rodent model. ..
  42. doi request reprint Biodegradation mechanisms of iron oxide monocrystalline nanoflowers and tunable shield effect of gold coating
    Yasir Javed
    Laboratoire Matériaux et Phénomènes Quantiques, UMR 7162 CNRS Université Paris Diderot, 10 rue Alice Domon et Leonie Duquet, F 75205, Paris Cedex 13, France
    Small 10:3325-37. 2014
    ..Such inorganic nanoshields could be a relevant strategy to modulate the degradability and ultimately the long term fate of nanomaterials in the organism...
  43. doi request reprint Magnetic labeling, imaging and manipulation of endothelial progenitor cells using iron oxide nanoparticles
    Florence Gazeau
    Laboratoire Matière et Systèmes Complexes, UMR 7057 CNRS Université Paris Diderot, Paris, France florence gazeau univ paris diderot fr
    Future Med Chem 2:397-408. 2010
    ..Finally, we show that remotely applied magnetic forces may enable intracellular manipulation and may optimize cell-delivery strategies for localizing cell therapy to target sites...
  44. doi request reprint Degradability of superparamagnetic nanoparticles in a model of intracellular environment: follow-up of magnetic, structural and chemical properties
    Michael Levy
    Laboratoire Matière et Systèmes Complexes, UMR 7057, CNRS and Université Paris Diderot, Paris, France
    Nanotechnology 21:395103. 2010
    ..This result suggests a model for nanoparticle degradation with rapidly dissolved nanocrystals and a reservoir of intact nanoparticles...
  45. pmc Massive release of extracellular vesicles from cancer cells after photodynamic treatment or chemotherapy
    Kelly Aubertin
    Laboratoire Matière et Systèmes Complexes, UMR 7057, CNRS and Université Paris Diderot, 10 rue Alice Domon et Leonie Duquet, 75205 Paris Cedex 13, France
    Sci Rep 6:35376. 2016
    ..In vivo, photodynamic treatment and chemotherapy increased the levels of circulating EVs several fold, confirming the vast induction of cancer cell vesiculation triggered by anti-cancer therapies...
  46. pmc In vivo determination of fluctuating forces during endosome trafficking using a combination of active and passive microrheology
    Damien Robert
    Laboratoire Matiere et Systemes Complexes MSC, UMR 7057 CNRS et Université Paris Diderot, Paris, France
    PLoS ONE 5:e10046. 2010
    ..Regulation of intracellular trafficking is a central issue in cell biology. The forces acting on intracellular vesicles (endosomes) can be assessed in living cells by using a combination of active and passive microrheology...
  47. doi request reprint Magnetic micro-manipulations to probe the local physical properties of porous scaffolds and to confine stem cells
    Damien Robert
    Laboratoire Matiere et Systemes Complexes MSC, UMR 7057 CNRS and Université Paris Diderot, Paris, France
    Biomaterials 31:1586-95. 2010
    ..The magnetic forces were also successfully applied to the stem cells to enhance the cell seeding process and impose a well defined spatial organization into the scaffold...
  48. pmc Impact of photosensitizers activation on intracellular trafficking and viscosity
    Kelly Aubertin
    Laboratoire Matiere et Systemes Complexes MSC, CNRS and Université Paris Diderot, Paris, France
    PLoS ONE 8:e84850. 2013
    ..These two agents demonstrated different intracellular impact. ..
  49. doi request reprint The role of cell-released microvesicles in the intercellular transfer of magnetic nanoparticles in the monocyte/macrophage system
    Nathalie Luciani
    Laboratoire Matière et Systèmes Complexes, UMR 7057, CNRS and Université Paris Diderot, 10 rue Alice Domon et Leonie Duquet, Paris Cedex 13, France
    Biomaterials 31:7061-9. 2010
    ..Intercellular transfer of magnetic label, mediated by cell-released vesicles, complicates the picture of nanoparticles outcome in the organism and their use as MRI cell tracers...
  50. doi request reprint Formation of a three-dimensional multicellular assembly using magnetic patterning
    Guillaume Frasca
    Laboratoire Matiere et Systemes Complexes MSC, UMR 7057 CNRS and Université Paris Diderot, Paris Cedex 13, F 75205, France
    Langmuir 25:2348-54. 2009
    ....
  51. doi request reprint Photothermal Therapy: Cancer Cell Internalization of Gold Nanostars Impacts Their Photothermal Efficiency In Vitro and In Vivo: Toward a Plasmonic Thermal Fingerprint in Tumoral Environment (Adv. Healthcare Mater. 9/2016)
    Ana Espinosa
    Laboratoire Matiere et Systemes Complexes MSC, UMR 7057, CNRS and Université Paris Diderot, 75205, Paris Cedex 13, France
    Adv Healthc Mater 5:1112. 2016
    ..Wilhelm and team provide the first in vitro and in vivo photothermal measurements in cancer cells with gold nanostars. They demonstrate that once nanostars are internalized within endosomes, heat generation can change significantly. ..
  52. doi request reprint Massive Intracellular Biodegradation of Iron Oxide Nanoparticles Evidenced Magnetically at Single-Endosome and Tissue Levels
    Francois Mazuel
    Laboratoire Matiere et Systemes Complexes MSC, UMR 7057, CNRS and Université Paris Diderot, 75205 Cedex 05 Paris, France
    ACS Nano 10:7627-38. 2016
    ....
  53. doi request reprint Intercellular carbon nanotube translocation assessed by flow cytometry imaging
    Iris Marangon
    CNRS Universite Paris Diderot, PRES Sorbonne Paris Cité, Laboratoire Matiere et Systemes Complexes MSC, UMR7057, 75205 Paris Cedex 13, France
    Nano Lett 12:4830-7. 2012
    ..This finding raises new critical issues for nanotoxicology, since carbon nanotubes could be disseminated by circulating extracellular cell-released vesicles and visiting several cells in the course of their passage into the organism...
  54. ncbi request reprint Magnetic nanomanipulations inside living cells compared with passive tracking of nanoprobes to get consensus for intracellular mechanics
    Damien Robert
    Laboratoire Matière et Systèmes Complexes, CNRS UMR 7057, Universite Paris 7, 75013 Paris, France
    Phys Rev E Stat Nonlin Soft Matter Phys 85:011905. 2012
    ..However, when data on these probes' viscoelastic microenvironment is available, such passive probe movements can yield useful information on the forces responsible for intracellular activity...
  55. doi request reprint Managing magnetic nanoparticle aggregation and cellular uptake: a precondition for efficient stem-cell differentiation and MRI tracking (adv. Healthcare mater. 2/2013)
    Delphine Fayol
    Laboratoire Matiere et Systemes Complexes MSC, UMR 7057 CNRS and University Paris Diderot, Paris, France
    Adv Healthc Mater 2:312. 2013
    ..aggregation and the amount of internalized iron on capacity for stem-cell differentiation is examined by Claire Wilhelm and co-workers on page 313...
  56. ncbi request reprint Magnetic targeting of magnetoliposomes to solid tumors with MR imaging monitoring in mice: feasibility
    Jean Paul Fortin-Ripoche
    Laboratoire Matière et Systèmes Complexes, Groupe Physique du Vivant, Universite Paris 7, MSc, 140 rue de Lourmel, 75015 Paris, France
    Radiology 239:415-24. 2006
    ..To establish the feasibility of magnetoliposome tumor targeting with an extracorporeal magnet...
  57. ncbi request reprint Magnetic nanomanipulations inside living cells compared with passive tracking of nanoprobes to get consensus for intracellular mechanics
    Damien Robert
    Laboratoire Matière et Systèmes Complexes, CNRS UMR 7057, Universite Paris 7, 75013 Paris, France
    Phys Rev E Stat Nonlin Soft Matter Phys 85:011905. 2012
    ..However, when data on these probes' viscoelastic microenvironment is available, such passive probe movements can yield useful information on the forces responsible for intracellular activity...
  58. ncbi request reprint Linear patterning of magnetically labeled Dictyostelium cells to display confined development
    Guillaume Frasca
    Laboratoire Matiere et Systemes Complexes MSC, UMR 7057 CNRS et Université Paris Diderot, Paris, France
    J Phys Condens Matter 20:204149. 2008
    ..This structure evolves during the aggregation phase, forming periodic aggregative centers along the linear initial pattern...
  59. ncbi request reprint Magnetically induced hyperthermia: size-dependent heating power of γ-Fe(2)O(3) nanoparticles
    Michael Levy
    Laboratoire Matiere et Systemes Complexes MSC, UMR CNRS 7057, Universite Paris Diderot, Bâtiment Condorcet Case 7056, F 75205 Paris Cedex 13, France
    J Phys Condens Matter 20:204133. 2008
    ..In agreement with theoretical predictions, the heating efficiency shows a maximum for an optimal size of about 15 nm...
  60. ncbi request reprint Myosin Ib modulates the morphology and the protein transport within multi-vesicular sorting endosomes
    Laura Salas-Cortes
    Institut Curie, CNRS UMR144, 26 Rue d Ulm, 75248, Paris, Cedex 05, France
    J Cell Sci 118:4823-32. 2005
    ..All together, these observations suggest that myosin 1b controls the traffic of protein cargo in multivesicular endosomes most probably through its ability to modulate with actin the morphology of these sorting endosomes...
  61. ncbi request reprint Magnetic flattening of stem-cell spheroids indicates a size-dependent elastocapillary transition
    Francois Mazuel
    Laboratoire Matière et Systèmes Complexes, UMR 7057, CNRS, Universite Paris Diderot, 75013 Paris, France
    Phys Rev Lett 114:098105. 2015
    ....
  62. ncbi request reprint Single-cell detection by gradient echo 9.4 T MRI: a parametric study
    P Smirnov
    Laboratoire Matière et Systèmes Complexes, Universite Paris 7, Denis Diderot and CNRS UMR 7057, 140, rue de Lourmel, 75015 Paris, France
    Contrast Media Mol Imaging 1:165-74. 2006
    ..We then conducted a systematic study in order to determine the gradient echo sequence parameters (echo time, cell magnetization and resolution) most suitable for in vivo identification of single cells...
  63. ncbi request reprint Signaling through the phosphatidylinositol 3-kinase regulates mechanotaxis induced by local low magnetic forces in Entamoeba histolytica
    C Riviere
    Pôle Matière et Systèmes Complexes, Universite Paris 7, Denis Diderot, CNRS UMR7057, 140, rue de Lourmel, 75015 Paris, France
    J Biomech 40:64-77. 2007
    ..This result demonstrated that the applied mechanical stimulus was transduced and amplified into an intracellular biochemical signal, a process that allows such low-intensity force to strongly modify the migration behavior of the cell...
  64. ncbi request reprint Overexpression of myosin IB in living Entamoeba histolytica enhances cytoplasm viscosity and reduces phagocytosis
    Sabrina Marion
    Unité de Biologie Cellulaire du Parasitisme, INSERM U389, Institut Pasteur, 28 rue du Dr Roux 75724, Paris Cedex 15, France
    J Cell Sci 117:3271-9. 2004
    ..The gelation state of cell cytoplasm and the dynamics of cortical F-actin during phagocytosis seem to be modulated by the myosin IB structuring cytoskeleton activity...
  65. doi request reprint The effect of magnetic targeting on the uptake of magnetic-fluid-loaded liposomes by human prostatic adenocarcinoma cells
    Marie Sophie Martina
    Equipe Physico Chimie des Systèmes Polyphasés, CNRS UMR 8612, F 92296 Châtenay, Malabry Cedex, France
    Biomaterials 29:4137-45. 2008
    ..This demonstrated that MFL associate with tumor cells as intact vesicle structures which conserve their internal content...
  66. doi request reprint Different microtubule motors move early and late endocytic compartments
    Sylvain Loubéry
    Institut Curie, Centre de Recherche, Paris 75248, France
    Traffic 9:492-509. 2008
    ..These data provide new insights into the complex regulation of endosomes' motility and suggest that dynein is not the major motor required to move late endosomes toward the minus end of microtubules...
  67. pmc In vivo imaging of transplanted hepatocytes with a 1.5-T clinical MRI system--initial experience in mice
    Alain Luciani
    Assistance Publique Hopitaux de Paris, Radiology Department, CHU Henri Mondor, Creteil, France
    Eur Radiol 18:59-69. 2008
    ..01) with minimal T2 values demonstrated 8 days after transplantation. Conventional MRI can demonstrate the presence of transplanted iron-labeled mature hepatocytes in mouse liver...
  68. ncbi request reprint The in vitro kinetics of the interactions between PEG-ylated magnetic-fluid-loaded liposomes and macrophages
    Marie Sophie Martina
    Equipe Physico Chimie des Systèmes Polyphasés, CNRS UMR 8612, F 92296 Chatenay Malabry Cedex, France
    Biomaterials 28:4143-53. 2007
    ..Moreover, lipids and iron oxide particle uptakes were perfectly correlated, indicating that MFL vesicle structure and encapsulation rate were preserved upon cell penetration...
  69. ncbi request reprint Fluorescence-modified superparamagnetic nanoparticles: intracellular uptake and use in cellular imaging
    Franck Bertorelle
    Laboratoire des Liquides Ioniques et Interfaces Chargées, Équipe Colloïdes Inorganiques, UMR 7612 CNRS Université Pierre et Marie Curie Paris 6, 4 place Jussieu, case 63, 75252 Paris, Cedex 05, France
    Langmuir 22:5385-91. 2006
    ..Finally, by measuring the critical cellular magnetic load (quantitated by magnetophoresis), we have demonstrated the potential of this new magneto-fluorescent nanoagent for medical use...