Vincent Thibault

Summary

Country: France

Publications

  1. doi request reprint Six-year follow-up of hepatitis B surface antigen concentrations in tenofovir disoproxil fumarate treated HIV-HBV-coinfected patients
    Vincent Thibault
    Virology Laboratory, Hopital Pitie Salpetriere, Assistance Publique, Paris, France
    Antivir Ther 16:199-205. 2011
  2. ncbi request reprint Serum biochemical markers accurately predict liver fibrosis in HIV and hepatitis C virus co-infected patients
    Robert P Myers
    Department of Hepatology and Gastroenterology, hôpital La Pitié Salpêtrière, Paris, France
    AIDS 17:721-5. 2003
  3. ncbi request reprint Hepatitis C virus infection in systemic lupus erythematosus: a case-control study
    Gabriel Perlemuter
    Service d hépatologie et de gastroentérologie, Hopital de Bicetre, Kremlin Bicetre, Paris, France
    J Rheumatol 30:1473-8. 2003
  4. ncbi request reprint Decreased frequencies of virus-specific T helper type 1 cells during interferon alpha plus ribavirin treatment in HIV-hepatitis C virus co-infection
    Nadia Alatrakchi
    Laboratoire d Immunologie Cellulaire et Tissulaire INSERM U543, Centre Hospitalier Universitaire Pitie Salpetriere, Paris, France
    AIDS 18:121-3. 2004
  5. doi request reprint Low levels of hepatitis C virus (HCV) neutralizing antibodies in patients coinfected with HCV and human immunodeficiency virus
    Sandrine Castelain
    Virologie, CHU Hopital Sud, Amiens, France
    J Infect Dis 198:332-5. 2008
  6. pmc Epidemiological, virological and clinical characteristics of HBV infection in 223 HIV co-infected patients: a French multi-centre collaborative study
    Vincent Thibault
    Pitie Salpetriere, Paris, France
    Virol J 10:87. 2013
  7. doi request reprint Hepatitis C transmission in injection drug users: could swabs be the main culprit?
    Vincent Thibault
    Virology Laboratory, Hopital Pitie Salpetriere, Assistance Publique, and Pierre et Marie Curie University, France
    J Infect Dis 204:1839-42. 2011
  8. pmc Molecular analysis of HBV genotypes and subgenotypes in the Central-East region of Tunisia
    Naila Hannachi
    Laboratoire de microbiologie immunologie, UR02SP13, Hôpital Farhat Hached, Sousse, Tunisia
    Virol J 7:302. 2010
  9. pmc Characterization of a new sensitive PCR assay for quantification of viral DNA isolated from patients with hepatitis B virus infections
    Vincent Thibault
    Laboratoire de Virologie CERVI, Hopital de la Pitie Salpetriere, 83 bd de l hopital, 75651, Paris Cedex 13, France
    J Clin Microbiol 45:3948-53. 2007
  10. doi request reprint Impact of hepatitis B virus genotypes and surface antigen variants on the performance of HBV real time PCR quantification
    Vincent Thibault
    Laboratoire de Virologie, AP HP Hôpital de la Pitié Salpêtrière, Paris, France
    J Virol Methods 159:265-70. 2009

Detail Information

Publications67

  1. doi request reprint Six-year follow-up of hepatitis B surface antigen concentrations in tenofovir disoproxil fumarate treated HIV-HBV-coinfected patients
    Vincent Thibault
    Virology Laboratory, Hopital Pitie Salpetriere, Assistance Publique, Paris, France
    Antivir Ther 16:199-205. 2011
    ..Our main objective was to study the kinetics of HBsAg level in HIV-HBV-coinfected patients with undetectable HBV DNA load under treatment containing tenofovir disoproxil fumarate (TDF)...
  2. ncbi request reprint Serum biochemical markers accurately predict liver fibrosis in HIV and hepatitis C virus co-infected patients
    Robert P Myers
    Department of Hepatology and Gastroenterology, hôpital La Pitié Salpêtrière, Paris, France
    AIDS 17:721-5. 2003
    ..Our aim was to determine the operating characteristics of a non-invasive index of biochemical markers for the prediction of fibrosis in patients with HIV/HCV co-infection...
  3. ncbi request reprint Hepatitis C virus infection in systemic lupus erythematosus: a case-control study
    Gabriel Perlemuter
    Service d hépatologie et de gastroentérologie, Hopital de Bicetre, Kremlin Bicetre, Paris, France
    J Rheumatol 30:1473-8. 2003
    ..Reports on the association between SLE and HCV infection are scarce. We investigated the association of HCV infection and SLE...
  4. ncbi request reprint Decreased frequencies of virus-specific T helper type 1 cells during interferon alpha plus ribavirin treatment in HIV-hepatitis C virus co-infection
    Nadia Alatrakchi
    Laboratoire d Immunologie Cellulaire et Tissulaire INSERM U543, Centre Hospitalier Universitaire Pitie Salpetriere, Paris, France
    AIDS 18:121-3. 2004
    ..This suggests that IFN+R therapy might compromise virus-specific immune defenses in immunosuppressed patients...
  5. doi request reprint Low levels of hepatitis C virus (HCV) neutralizing antibodies in patients coinfected with HCV and human immunodeficiency virus
    Sandrine Castelain
    Virologie, CHU Hopital Sud, Amiens, France
    J Infect Dis 198:332-5. 2008
    ..912+/-0.578) (P= .013). Lower HCV nAb titers in coinfected patients could help worsen the outcome of HCV infection. These results favor starting HCV therapy as soon as possible in coinfected patients...
  6. pmc Epidemiological, virological and clinical characteristics of HBV infection in 223 HIV co-infected patients: a French multi-centre collaborative study
    Vincent Thibault
    Pitie Salpetriere, Paris, France
    Virol J 10:87. 2013
    ....
  7. doi request reprint Hepatitis C transmission in injection drug users: could swabs be the main culprit?
    Vincent Thibault
    Virology Laboratory, Hopital Pitie Salpetriere, Assistance Publique, and Pierre et Marie Curie University, France
    J Infect Dis 204:1839-42. 2011
    ..However, HCV RNA was frequently found on syringe pools (38%) and on swabs (82%) at high titers. Our investigation, which was conducted in real injecting settings, highlights swabs as a potential source for HCV transmission...
  8. pmc Molecular analysis of HBV genotypes and subgenotypes in the Central-East region of Tunisia
    Naila Hannachi
    Laboratoire de microbiologie immunologie, UR02SP13, Hôpital Farhat Hached, Sousse, Tunisia
    Virol J 7:302. 2010
    ..HBV genotyping methods were: PCR-RFLP on the pre-S region, a PCR using type-specific primers in the S region (TSP-PCR) and partial sequencing in the pre-S region...
  9. pmc Characterization of a new sensitive PCR assay for quantification of viral DNA isolated from patients with hepatitis B virus infections
    Vincent Thibault
    Laboratoire de Virologie CERVI, Hopital de la Pitie Salpetriere, 83 bd de l hopital, 75651, Paris Cedex 13, France
    J Clin Microbiol 45:3948-53. 2007
    ..Its sensitivity and wide dynamic range should allow optimal monitoring of antiviral therapy and timely treatment adaptation...
  10. doi request reprint Impact of hepatitis B virus genotypes and surface antigen variants on the performance of HBV real time PCR quantification
    Vincent Thibault
    Laboratoire de Virologie, AP HP Hôpital de la Pitié Salpêtrière, Paris, France
    J Virol Methods 159:265-70. 2009
    ..In conclusion, the Abbott RT assay can detect and quantify DNA from different HBV variants with equivalent performance and is thus suitable for routine monitoring of patients with chronic HBV infections...
  11. ncbi request reprint A prospective analysis of the prognostic value of biomarkers (FibroTest) in patients with chronic hepatitis C
    Yen Ngo
    Service d Hepato Gastroenterologie, Groupe Hospitalier Pitie Salpetriere, CNRS, Paris, France
    Clin Chem 52:1887-96. 2006
    ..We compared the 5-year prognostic value of the FibroTest with biopsy staging for predicting cirrhosis decompensation and survival in patients with chronic HCV infection...
  12. ncbi request reprint Efficacy and safety of adefovir dipivoxil plus pegylated interferon-alpha2a for the treatment of lamivudine-resistant hepatitis B virus infection in HIV-infected patients
    Patrick Ingiliz
    Hepatology Department, Pitie Salpetriere Hospital, Paris, France
    Antivir Ther 13:895-900. 2008
    ..Adefovir dipivoxil (ADV) has shown its efficacy for treating 3TC-resistant (3TC-R) HBV in HIV-coinfected patients. ADV combined with pegylated interferon (PEG-IFN) has never been evaluated in this population...
  13. ncbi request reprint Hepatitis C in 6,865 patients 65 yr or older: a severe and neglected curable disease?
    Dominique Thabut
    Services d Hépato gastroentérologie, Group Hospitalier Pitié Salpêtrièe, Paris, France
    Am J Gastroenterol 101:1260-7. 2006
    ....
  14. ncbi request reprint Safety and efficacy of adefovir dipivoxil in patients infected with lamivudine-resistant hepatitis B and HIV-1
    Yves Benhamou
    Groupe Hospitalier Pitie Salpetriere, Service de d Hépato Gastroentérologie, Paris, France
    J Hepatol 44:62-7. 2006
    ..Adefovir dipivoxil (10 mg once-daily) was added to antiretroviral therapy including lamivudine in 35 HIV/HBV co-infected patients...
  15. ncbi request reprint Pegylated interferon alpha 2b and ribavirin in HIV/hepatitis C virus-co-infected non-responders and relapsers to IFN-based therapy
    Robert P Myers
    Service d Hepato Gastroenterologie, Groupe Hospitalier Pitie Salpetriere, Paris, France
    AIDS 18:75-9. 2004
    ..Pegylated interferon alpha (PEG-IFN-alpha) and ribavirin is the most effective available treatment for chronic hepatitis C virus (HCV) infection. Its role in HIV/HCV-co-infected patients who have failed IFN-based therapy is unclear...
  16. ncbi request reprint In vitro susceptibility of lamivudine-resistant hepatitis B virus to adefovir and tenofovir
    Olivier Lada
    Virology, AP HP Pitié Salpêtrière Hospital, Paris, France
    Antivir Ther 9:353-63. 2004
    ..The excellent activity of TDF on lamivudine-resistant virus independently of the resistance mutation profile offers an interesting treatment alternative to HIV-HBV coinfected patients...
  17. doi request reprint Role of genotype G hepatitis B virus mixed infection on the progression of hepatic fibrosis in HIV positive patients over 5 years of follow-up
    Ruxandra Călin
    AP HP, Service des Maladies Infectieuses, Hopital Pitie Salpetriere, Paris, France
    J Clin Virol 58:408-14. 2013
    ..The dynamic of liver disease in co-infected patients is important to understand for appropriate clinical management. Conflicting data surround the role played by genotype-G HBV (HBV-G) during the course of HIV co-infection...
  18. ncbi request reprint Long-term therapy with lamivudine in renal transplant recipients with chronic hepatitis B
    Dominique Thabut
    Hepato Gastroenterology Unit, Hopital Pitie Salpetriere, Paris, France
    Eur J Gastroenterol Hepatol 16:1367-73. 2004
    ..The clinical features, course and viral mutations associated with the emergence of viral resistance in this population have not been well studied...
  19. doi request reprint Lack of TGF-β production by hepatitis C virus-specific T cells during HCV acute phase is associated with HCV clearance in HIV coinfection
    Sawsan Harfouch
    INSERM, UMRS 945, Laboratoire Immunité et Infection, Hopital Pitie Salpetriere, F 75013 Paris, France
    J Hepatol 56:1259-68. 2012
    ..We investigated whether early T cell responses to HCV producing transforming-growth-factor beta (TGF-β) predict the outcome of acute HCV coinfection, independently of the IL-28B gene polymorphism...
  20. ncbi request reprint Intra-laboratory analytical variability of biochemical markers of fibrosis (Fibrotest) and activity (Actitest) and reference ranges in healthy blood donors
    Francoise Imbert-Bismut
    Service of Biochemistry, hôpital La Pitié Salpêtrière, Paris, France
    Clin Chem Lab Med 42:323-33. 2004
    ..075+/-0.004 and 0.068+/-0.004, respectively. The low intra-laboratory and intra-patient variability in Fibrotest and Actitest results confirm Fibrotest and Actitest reliability...
  21. ncbi request reprint Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C
    Thierry Poynard
    Service d Hepato Gastroenterologie, Groupe Hospitalier Pitie Salpetriere, Universite Paris VI, Paris, France
    Clin Chem 50:1344-55. 2004
    ....
  22. ncbi request reprint Prediction of liver histological lesions with biochemical markers in patients with chronic hepatitis B
    Robert P Myers
    Department of Hepatology and Gastroenterology, Groupe Hospitalier Pitie Salpetriere, Paris, France
    J Hepatol 39:222-30. 2003
    ..Liver biopsy is the gold standard for assessing hepatitis B virus (HBV)-related histology. The aim was to determine the diagnostic utility of noninvasive serum markers in patients with chronic hepatitis B...
  23. pmc An accurate definition of the status of inactive hepatitis B virus carrier by a combination of biomarkers (FibroTest-ActiTest) and viral load
    Yen Ngo
    Service d Hepato Gastroenterologie, Groupe Hospitalier Pitie Salpetriere, Universite Paris VI, CNRS UMR 8149, Paris, France
    PLoS ONE 3:e2573. 2008
    ..We compared the 4-year prognostic value of combining FT-AT and viral load for a better definition of the inactive carrier status...
  24. ncbi request reprint Antiviral therapy for hepatitis C virus--associated mixed cryoglobulinemia vasculitis: a long-term followup study
    David Saadoun
    hôpital La Pitié Salpêtrière, Paris, France
    Arthritis Rheum 54:3696-706. 2006
    ..To evaluate the long-term efficacy of anti-hepatitis C virus (HCV) therapy in patients with HCV-associated mixed cryoglobulinemia (HCV-MC) vasculitis and to assess the factors associated with clinical remission of MC...
  25. doi request reprint Anti-hepatitis C virus antibody detection in oral fluid: influence of human immunodeficiency virus co-infection
    Benoit Visseaux
    Laboratoire de Virologie, Hopital Bichat Claude Bernard, Groupe Hospitalier Paris Nord Val de Seine, APHP, 46 rue Henri Huchard, 75018 Paris, France
    J Clin Virol 58:385-90. 2013
    ..Saliva sampling may provide an easier access to hepatitis C virus (HCV) screening test. HIV infection influence on specific salivary antibody detection has not been extensively studied...
  26. pmc Interpretation of real-time PCR results for hepatitis C virus RNA when viral load is below quantification limits
    Syria Laperche
    Centre National de Référence pour les Hépatites B et C en Transfusion, Département des Agents Transmissibles par le Sang, Institut National de la Transfusion Sanguine, Paris, France
    J Clin Microbiol 49:1113-5. 2011
    ..5 to 500 IU/ml) showed a score of correct results of up to 93.5%. However, 55.6% of the laboratories did not follow the recommendations for the interpretation of their results, leading to ambiguous conclusions...
  27. ncbi request reprint Longitudinal assessment of histology surrogate markers (FibroTest-ActiTest) during lamivudine therapy in patients with chronic hepatitis B infection
    Thierry Poynard
    Department of Hepatology and Gastroenterology, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Am J Gastroenterol 100:1970-80. 2005
    ..The aim was to use these markers in a prospective study of patients treated with lamivudine in order to assess the impact of treatment, as well as the factors associated with fibrosis progression...
  28. doi request reprint Influence of the HCV subtype on the virological response to pegylated interferon and ribavirin therapy
    Florence Legrand-Abravanel
    Laboratoire de Virologie, Centre Hospitalier Universitaire, Toulouse, France
    J Med Virol 81:2029-35. 2009
    ..0-2.5; P = 0.04) or subtypes 4a and 4d (OR: 2.03; 95% CI = 1.1-3.8; P = 0.03). In conclusion, among difficult-to-treat genotypes, the subtype 1a is associated with a lower response to anti-HCV therapy than subtypes 1b, 4a, and 4d...
  29. ncbi request reprint Longterm course of mixed cryoglobulinemia in patients infected with hepatitis C virus
    Damien Sene
    Department of Internal Medicine, hôpital La Pitié Salpêtrière, Paris, France
    J Rheumatol 31:2199-206. 2004
    ..To describe epidemiological, clinical, and immunological characteristics and the longterm course of persistent mixed cryoglobulinemia (MC) in patients infected with hepatitis C virus (HCV)...
  30. doi request reprint Acute hepatitis C in HIV-infected patients: rare spontaneous clearance correlates with weak memory CD4 T-cell responses to hepatitis C virus
    Aurelie Schnuriger
    INSERM, UMRS 945, Paris, France
    AIDS 23:2079-89. 2009
    ..To explore the parameters of specific immunity to hepatitis C virus (HCV) associated with virus clearance during acute HCV infection in HIV coinfection...
  31. pmc Expertise of laboratories in viral load quantification, genotyping, and precore mutant determination for hepatitis B virus in a multicenter study
    Syria Laperche
    Centre National de Référence pour les Hépatites B et C en Transfusion, Département des Agents Transmissibles par le Sang, Institut National de la Transfusion Sanguine, Paris, France
    J Clin Microbiol 44:3600-7. 2006
    ..Furthermore, the clinical implications of HBV genotyping and the determination of precore/core mutants need to be clearly stated to justify the standardization of these methods...
  32. doi request reprint Evolutionary history of hepatitis C virus genotype 5a in France, a multicenter ANRS study
    Cecile Henquell
    CHU de Clermont Ferrand, Centre de Biologie, Laboratoire de Virologie, F 63003 Clermont Ferrand, France
    Infect Genet Evol 11:496-503. 2011
    ..Phylodynamic analyses give a plausible reconstruction of the evolutionary history of HCV genotype 5a in France, suggesting the concomitant roles of transfusion, iatrogenic route and intra-familial transmission in viral diffusion...
  33. doi request reprint Adjustment of antiretroviral regimen may lead to HBV reactivation even in patients with past HBV infection serological profile
    Sophie Seang
    INSERM UMR S 943 and University Pierre and Marie Curie UPMC Paris VI, Paris, France
    J Infect Chemother 19:987-9. 2013
    ..In HBV-HIV co-infected patients, close monitoring of HBV viral load and serological markers is required for antiretroviral management, particularly after interruption of drugs active for HBV. ..
  34. pmc Multicenter trials need to use the same assay for hepatitis C virus viral load determination
    Syria Laperche
    Centre National de Référence pour les Hépatites B et C en Transfusion, Département des Agents Transmissibles par le Sang, Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, 75015, Paris, France
    J Clin Microbiol 45:3788-90. 2007
    ..This underlines the importance of using the same assay in multicenter studies or when monitoring antiviral therapy...
  35. pmc A focus reduction neutralization assay for hepatitis C virus neutralizing antibodies
    Carole Fournier
    Laboratoire de Virologie, Centre Hospitalo Universitaire, Amiens, France
    Virol J 4:35. 2007
    ..Based on the recent development of a HCV cell culture system using the genotype 2 JFH-1-strain, we developed a focus reduction assay for HCV-neutralizing antibodies...
  36. doi request reprint Fatal fulminant primary hepatitis B virus infections with G1896A precore viral mutants in southeastern France
    Laure Panassié
    Laboratoire de Virologie, Pôle des Maladies Infectieuses et Tropicales Clinique et Biologique, Fédération de Bactériologie Hygiène Virologie, CHU Timone, 264, rue Saint Pierre, 13385 Marseille Cedex 05, France
    Clin Res Hepatol Gastroenterol 36:e1-8. 2012
    ..Primary HBV infection remains a cause of death in France. The impact of the precore G1896A mutation on the severity of AHB deserves to be assessed in larger studies in this country...
  37. doi request reprint Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis
    David Saadoun
    Université Pierre et Marie Curie Université Paris 06, Paris, France
    N Engl J Med 365:2067-77. 2011
    ..We reasoned that interleukin-2, a cytokine that promotes Treg survival and function, could be beneficial for patients with vasculitis that is resistant to HCV therapy...
  38. doi request reprint Staging chronic hepatitis B into seven categories, defining inactive carriers and assessing treatment impact using a fibrosis biomarker (FibroTest®) and elastography (FibroScan®)
    Thierry Poynard
    Assistance Publique Hopitaux de Paris AP HP, Groupe Hospitalier Pitie Salpetriere, Paris, France University Pierre et Marie Curie UPMC University of Paris VI, Paris, France INSERM, UMRS 938, Paris, France Electronic address
    J Hepatol 61:994-1003. 2014
    ..The second aim was to validate a previous definition of an inactive carrier based on normal FT and ActiTest® (normal-FT-AT). The third aim was to assess the long-term dynamics of fibrosis in patients with sustained virological response...
  39. pmc Sequencing assays for failed genotyping with the versant hepatitis C virus genotype assay (LiPA), version 2.0
    Sylvie Larrat
    Laboratoire de Virologie, Département des Agents Infectieux, Pôle Biologie, Centre Hospitalier Universitaire Grenoble, Grenoble, France
    J Clin Microbiol 51:2815-21. 2013
    ..0 assay (LiPA) and also underlines the need for a complex combination of sequences and phylogenetic analyses in order to genotype these particular HCV strains correctly. ..
  40. pmc Human immunodeficiency virus (HIV) Type 1 reverse transcriptase resistance mutations in hepatitis B virus (HBV)-HIV-coinfected patients treated for HBV chronic infection once daily with 10 milligrams of adefovir dipivoxil combined with lamivudine
    Constance Delaugerre
    Department of Virology, Pitie Salpetriere Hospital, Paris, France
    Antimicrob Agents Chemother 46:1586-8. 2002
    ....
  41. pmc Coexistence of hepatitis B surface antigen (HBs Ag) and anti-HBs antibodies in chronic hepatitis B virus carriers: influence of "a" determinant variants
    Olivier Lada
    Departments of Virology, Hepato Gastro Enterology, AP HP Pitié Salpêtrière Hospital, Paris, France
    J Virol 80:2968-75. 2006
    ..The consequences of this selection process with regard to vaccine efficacy, diagnosis, and clinical evolution remain partially unknown...
  42. doi request reprint Hepatitis E infection in patients with severe alcoholic hepatitis: is there a place for systematic screening?
    Marika Rudler
    aAP HP, UPMC, Department of Hepatology and Gastroenterology bAP HP, UPMC, Department of Virology cAP HP, UPMC, Department of Anatomopathology, La Pitie Salpetriere Hospital, 47 80 Boulevard de l Hôpital, Assistance Publique Hopitaux de Paris, Pierre et Marie Curie University, Paris, France
    Eur J Gastroenterol Hepatol 27:1367-71. 2015
    ..6% of patients with severe alcoholic hepatitis (AH). However, validation of these preliminary results is lacking, as well as the impact of HEV infection on the 6-month survival...
  43. doi request reprint Coexistence of circulating HBsAg and anti-HBs antibodies in chronic hepatitis B carriers is not a simple analytical artifact and does not influence HBsAg quantification
    Marie Pancher
    AP HP, Pitie Salpetriere Hospital, Virology Department, Paris, France
    J Clin Virol 62:32-7. 2015
    ..Presence at the same time of HBsAg and anti-HBs antibodies (HBsAg/Ab) is an entity sometimes encountered in chronic hepatitis B (CHB) carriers...
  44. pmc Molecular epidemiology and clinical characteristics of hepatitis B identified through the French mandatory notification system
    Vincent Thibault
    Virology Laboratory, Hopital Pitie Salpetriere, Assistance Publique APHP, and Pierre et Marie Curie University, Paris, France
    PLoS ONE 8:e75267. 2013
    ..This study was first designed to analyze the molecular epidemiology of AHB and second to describe the differences between AHB and chronic hepatitis B (CHB) exacerbations...
  45. ncbi request reprint Interferon-alpha and ribavirin treatment in patients with hepatitis C virus-related systemic vasculitis
    Patrice Cacoub
    Department of Internal Medicine, hôpital La Pitié Salpêtrière, Paris, France
    Arthritis Rheum 46:3317-26. 2002
    ..Therefore, we retrospectively analyzed the response to treatment in patients with chronic hepatitis C complicated by systemic vasculitis who had received antiviral therapy with interferon-alpha (IFNalpha) and ribavirin...
  46. doi request reprint Sexually transmitted hepatitis C virus superinfection in HIV/hepatitis C virus co-infected men who have sex with men
    Jade Ghosn
    AP HP, EA MRT 3620, Universite Paris Descartes, Department of Virology, Necker Hospital, Paris, France
    AIDS 22:658-61. 2008
    ..HCV serology and serum HCV RNA should be examined periodically in HIV-infected men who have sex with men engaging in high-risk sexual behaviours...
  47. ncbi request reprint Strong CD4 Th1 responses to HIV and hepatitis C virus in HIV-infected long-term non-progressors co-infected with hepatitis C virus
    Nadia Alatrakchi
    Laboratoire d Immunologie Cellulaire, GH Pitié Salpétrière, Paris, France
    AIDS 16:713-7. 2002
    ..To compare the T-cell responses to hepatitis C virus (HCV) and HIV in HIV-infected long-term non-progressors (LT-NP) and HIV-positive progressors co-infected with HCV and in HIV-negative HCV-infected patients...
  48. ncbi request reprint Changing electrolyte and acido-basic profile in HIV-infected patients in the HAART era
    Corinne Isnard Bagnis
    Department of Nephrology, Pitie Salpetriere Hospital, AP HP and CERVI, Paris, France
    Nephron Physiol 103:p131-8. 2006
    ..HIV-infected patients may develop a variety of underreported metabolic abnormalities that may be classified into HIVAN, specific HIV abnormalities, coincidental renal disorders and anti-retroviral-treatment-induced side effects...
  49. ncbi request reprint TaqMan amplification system with an internal positive control for HCV RNA quantitation
    Sandrine Castelain
    Laboratoire de Virologie, CHU Hopital Sud, Faculte de Medecine, 80036 Amiens Cedex, France
    J Clin Virol 31:227-34. 2004
    ..Different quantitative HCV RNA assays have been reported, mainly using techniques based on signal amplification with branched DNA (bDNA) technology or target sequence amplification by reverse-transcription PCR method (RT-PCR)...
  50. doi request reprint Sofosbuvir plus ribavirin for hepatitis C virus-associated cryoglobulinaemia vasculitis: VASCUVALDIC study
    David Saadoun
    Inflammation Immunopathology Biotherapy Department DHU i2B, Sorbonne Universités, UPMC Univ Paris 06, Paris, France INSERM, UMR_S 959, Paris, France CNRS, FRE3632, Paris, France Groupe Hospitalier Pitié Salpêtrière, Department of Internal Medicine and Clinical Immunology, AP HP, Paris, France
    Ann Rheum Dis 75:1777-82. 2016
    ..Hepatitis C virus (HCV) is the aetiological agent for most cases of cryoglobulinaemia vasculitis. Interferon-containing regimens are associated with important side effects and may exacerbate the vasculitis...
  51. doi request reprint Performance of the DiaSorin LIAISON(®) anti-HBs II for the detection of hepatitis B surface antibodies: comparison with the Abbott Architect anti-HBs assay
    Sophie Kinn
    Virology Laboratory, Hopital Pitie Salpetriere, Assistance Publique APHP, and ER 1 Pierre et Marie Curie University, Paris 6, France
    J Clin Virol 50:297-302. 2011
    ..The widespread use of vaccines has highlighted the need for accurate and consistent quantification, yielding comparable quantitative results...
  52. pmc Successful rescue therapy with tenofovir in a patient with hepatic decompensation and adefovir resistant HBV mutant
    Vlad Ratziu
    Service d Hepatogastroenterologie, Hopital Pitié Salpetriere and Université Pierre et Marie Curie, Paris, France
    Comp Hepatol 5:1. 2006
    ..Initial reports of the rtN236T mutation showed preserved sensitivity to lamivudine; however, complex mutations are emerging with reduced susceptibility to lamivudine...
  53. doi request reprint Kinetic profiles and management of hepatitis B virus reactivation in patients with immune-mediated inflammatory diseases
    Nina Droz
    Universite Paris Descartes, AP HP, Hopital Cochin, Paris, France
    Arthritis Care Res (Hoboken) 65:1504-14. 2013
    ..We aimed to describe HBV reactivation in patients receiving treatment for immune-mediated inflammatory diseases (IMIDs) and to evaluate a predefined algorithm for its prevention...
  54. doi request reprint Lateral rectus muscle paralysis induced by ribavirin and pegylated interferon-α2a in a patient with HIV/HCV co-infection
    Guillaume Mellon
    Infectious Diseases Department, La Pitie Salpetriere Hospital, 83 Boulevard de l hopital, 75013 Paris, France
    J Infect Chemother 18:937-8. 2012
    ..Symptoms fully resolved with treatment interruption without any ophthalmological sequelae. This side effect is rare and has never been reported in a HIV-HCV co-infected patient...
  55. doi request reprint Assessment of adrenal function in cirrhotic patients: salivary cortisol should be preferred
    Arnaud Galbois
    Universite Pierre et Marie Curie, Service d Hepato Gastroenterologie, Hôpital de la Pitié Salpêtrière AP HP, Paris, France
    J Hepatol 52:839-45. 2010
    ....
  56. pmc Naturally Occurring Resistance-Associated Variants of Hepatitis C Virus Protease Inhibitors in Poor Responders to Pegylated Interferon-Ribavirin
    Sylvie Larrat
    Centre Hospitalier Universitaire Grenoble, Pôle Biologie, Laboratoire de Virologie, Département des Agents Infectieux, Grenoble, France Université Grenoble Alpes, Unit of Virus Host Cell Interactions UMI 3265 UJF EMBL CNRS, Grenoble, France
    J Clin Microbiol 53:2195-202. 2015
    ....
  57. doi request reprint PegIFNα/ribavirin/protease inhibitor combination in severe hepatitis C virus-associated mixed cryoglobulinemia vasculitis
    David Saadoun
    Department of Internal Medicine and Clinical Immunology, AP HP, Hopital Pitie Salpetriere, DHU i2B, Immunopathology, Inflammation, Biotherapy, Paris, France Université Pierre et Marie Curie, Paris VI, UMR CNRS 7211, INSERM U959, Hopital Pitie Salpetriere, Paris, France Electronic address
    J Hepatol 62:24-30. 2015
    ..The aim of this study was to analyse the safety and efficacy of the PegIFNα/ribavirin/protease inhibitor combination in severe and/or refractory hepatitis C virus (HCV)-mixed cryoglobulinemia (MC) vasculitis...
  58. doi request reprint [Beware of immunoglobulin's passive transfer when interpreting serological analyses!]
    Laëtitia Pinte
    CERVI hôpitaux universitaires La Pitié Salpêtrière Charles Foix, Laboratoire de Virologie, 75013 Paris, France
    Presse Med 45:676-81. 2016
    ..Interpretation of any serological test after IVIg administration should be particularly cautious. ..
  59. ncbi request reprint Human leukocyte antigen class II alleles may contribute to the severity of hepatitis C virus-related liver disease
    Sophie Hue
    Laboratory of Immunology, Hopital Necker, Paris, France
    J Infect Dis 186:106-9. 2002
    ..HLA class II alleles may weakly contribute to the severity of HCV liver disease. Of persons infected with HCV, only 15%-20% spontaneously clear the virus, and the rest become chronically infected...
  60. pmc Unique NS5b hepatitis C virus gene sequence consensus database is essential for standardization of genotype determinations in multicenter epidemiological studies
    Syria Laperche
    Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, 75015 Paris, France
    J Clin Microbiol 44:614-6. 2006
    ....
  61. ncbi request reprint Efficacy of early treatment of acute hepatitis C infection with pegylated interferon and ribavirin in HIV-infected patients
    Stephanie Dominguez
    Department of Infectious and Tropical Diseases INSERM U 720, CHU Pitie Salpetriere, 47 83 boulevard de l Hopital, 75651 Paris Cedex 13, France
    AIDS 20:1157-61. 2006
    ..Treatment of acute hepatitis C (HCV) in HIV-infected patients has been poorly addressed...
  62. ncbi request reprint Unusual selection of rtA181V HBV mutants cross-resistant to adefovir following prolonged lamivudine monotherapy: report of two cases
    Rene Gerolami
    Service d Hepato Gastroenterologie, Centre Hospitalier Universitaire Conception, Marseille, France
    Antivir Ther 11:1103-6. 2006
    ..Moreover, they highlight that HBV sequence analysis is an essential tool to optimize therapeutic management of HBV chronic infection in clinical practice in order to choose the appropriate nucleos(t)ide analogues...
  63. ncbi request reprint Interleukin 2 treatment does not modify hepatitis B or C replication in human immunodeficiency virus-infected patients: results from a randomized control trial
    Vincent Thibault
    Hepatology 35:238-9. 2002
  64. ncbi request reprint Tenofovir disoproxil fumarate in patients with HIV and lamivudine-resistant hepatitis B virus
    Yves Benhamou
    N Engl J Med 348:177-8. 2003
  65. ncbi request reprint Primary infection with a lamivudine-resistant hepatitis B virus
    Vincent Thibault
    AIDS 16:131-3. 2002
  66. pmc Comparison of hepatitis C virus NS5b and 5' noncoding gene sequencing methods in a multicenter study
    Syria Laperche
    Centre National de Référence pour les Hépatites B et C en Transfusion, Département des Agents Transmissible par le Sang, Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, 75015 Paris, France
    J Clin Microbiol 43:733-9. 2005
    ....
  67. ncbi request reprint Hepatitis B virus genotypes and extrahepatic manifestations
    Patrice Cacoub
    Department of Internal Medicine, hôpital La Pitié Salpêtrière, 83 Boulevard de l hopital, 75651 Paris Cedex 13, France
    J Hepatol 43:764-70. 2005
    ..This study aimed at correlating the presence of extrahepatic manifestations with hepatitis B virus (HBV) genotypes in patients with chronic HBV infection...