Ioannis Theodorou

Summary

Country: France

Publications

  1. ncbi request reprint High occurence of DRB1 11 in chronic lymphocytic leukaemia families
    Ioannis Theodorou
    Laboratoire Central d Immunologie Cellulaire Hôpital Pitié Salpêtrière, INSERM U550 Génétique Humaine des Maladies Infectieuses, Hopital Necker Enfants Malades, Paris, France
    Br J Haematol 119:713-5. 2002
  2. pmc Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection
    Etienne Patin
    Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Necker Medical School, INSERM Unité 980, Paris, France
    Gastroenterology 143:1244-52.e1-12. 2012
  3. pmc Impact of IL28B, APOH and ITPA Polymorphisms on Efficacy and Safety of TVR- or BOC-Based Triple Therapy in Treatment-Experienced HCV-1 Patients with Compensated Cirrhosis from the ANRS CO20-CUPIC Study
    Frédégonde About
    Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale INSERM U1163, Paris, France
    PLoS ONE 10:e0145105. 2015
  4. doi request reprint A new 3p25 locus is associated with liver fibrosis progression in human immunodeficiency virus/hepatitis C virus-coinfected patients
    Damien Ulveling
    Equipe Genomique, Bioinformatique et Applications EA4627, Chaire de Bioinformatique, Conservatoire National des Arts et Metiers, Paris, France
    Hepatology 64:1462-1472. 2016
  5. pmc Combined linkage and association studies show that HLA class II variants control levels of antibodies against Epstein-Barr virus antigens
    Vincent Pedergnana
    Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Sante et de la Recherche Medicale, Paris, France University Paris Descartes, Sorbonne Paris Cité, Imagine Institute, Paris, France
    PLoS ONE 9:e102501. 2014
  6. pmc Analysis of IL28B variants in an Egyptian population defines the 20 kilobases minimal region involved in spontaneous clearance of hepatitis C virus
    Vincent Pedergnana
    Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale U980, Paris, France
    PLoS ONE 7:e38578. 2012
  7. ncbi request reprint FAS promoter polymorphisms correlate with activity grade in hepatitis C patients
    Dorian McIlroy
    Laboratoire d Immunologie Cellulaire et Tissulaire bService de Gastroentérologie, Hopital Pitie Salpetriere, Paris, France
    Eur J Gastroenterol Hepatol 17:1081-8. 2005
  8. doi request reprint Genomewide association study of a rapid progression cohort identifies new susceptibility alleles for AIDS (ANRS Genomewide Association Study 03)
    Sigrid Le Clerc
    Conservatoire National des Arts et Metiers, Paris, France
    J Infect Dis 200:1194-201. 2009
  9. ncbi request reprint Deleterious genetic influence of CX3CR1 genotypes on HIV-1 disease progression
    Sophie Faure
    INSERM U543, Hopital Salpetriere, Paris, France
    J Acquir Immune Defic Syndr 32:335-7. 2003
  10. doi request reprint Genomewide association study of an AIDS-nonprogression cohort emphasizes the role played by HLA genes (ANRS Genomewide Association Study 02)
    Sophie Limou
    Conservatoire National des Arts et Metiers, Universite Paris 7, Paris, France
    J Infect Dis 199:419-26. 2009

Collaborators

  • Laurent Abel
  • Stanislas Pol
  • Markus H Heim
  • Dominique Salmon
  • Patrick Marcellin
  • Fabien Zoulim
  • Christophe Hezode
  • Matthew L Albert
  • Olivier Hermine
  • Pierre Yves Bochud
  • David R Booth
  • Jean Laurent Casanova
  • Jacob George
  • Ira M Jacobson
  • Jean Francois Dufour
  • Andrew H Talal
  • Christian Brechot
  • Vincent Pedergnana
  • Patrice Debre
  • Sigrid Le Clerc
  • Wassila Carpentier
  • Aurelie Cobat
  • Julien Guergnon
  • Taoufik Labib
  • Yves Levy
  • Jean Francois Zagury
  • Cedric Coulonges
  • Thierry Poynard
  • Sophie Limou
  • Dorian McIlroy
  • Damien Ulveling
  • Laurence Meyer
  • Frédégonde About
  • Andreas Cerny
  • Bertrand Nalpas
  • Etienne Patin
  • Jean Louis Spadoni
  • Christiane Deveau
  • Lieng Taing
  • Philippe Broet
  • Matthieu Montes
  • Serge Hercberg
  • Olivier Delaneau
  • Christian Dina
  • Amu Therwath
  • Philippe Froguel
  • Cyril Dalmasso
  • Christine Rouzioux
  • Ivo Gut
  • Jean Daniel Lelievre
  • François Schächter
  • Jean Francois Delfraissy
  • Rob Sladek
  • Rojo Ratsimandresy
  • Fumihiko Matsuda
  • Lokesh Agrawal
  • Asma Jlizi
  • Philippe Pellet
  • Sophie Faure
  • Francois Dabis
  • Josselin Noirel
  • Vincent Laville
  • Stephanie Dominguez
  • Jonathan Niay
  • Darragh Duffy
  • Tiphaine Oudot-Mellakh
  • Philippe Sultanik
  • Carole Cagnot
  • Pascaline Rabiega
  • Jean Pierre Bronowicki
  • Helene Fontaine
  • Fabrice Carrat
  • Dominique Larrey
  • Christophe Ferme
  • Catherine Le-Pendeven
  • Pauline Brice
  • Patrice Carde
  • Caroline Besson
  • Laurène Syx
  • Alexandre Alcais
  • Corinne Amiel
  • Yassine Taoufik
  • Darius Moradpour
  • Sabine Plancoulaine
  • Vijayaprakash Suppiah
  • David Semela
  • Charles M Rice
  • Graeme Stewart
  • Laurence Bousquet
  • Amira Mohsen

Detail Information

Publications13

  1. ncbi request reprint High occurence of DRB1 11 in chronic lymphocytic leukaemia families
    Ioannis Theodorou
    Laboratoire Central d Immunologie Cellulaire Hôpital Pitié Salpêtrière, INSERM U550 Génétique Humaine des Maladies Infectieuses, Hopital Necker Enfants Malades, Paris, France
    Br J Haematol 119:713-5. 2002
    ..009). A similar trend was also observed in a second series of nine French families (P = 0.002). Larger studies are needed to determine whether non-inherited paternal or maternal DRB1 antigens play a role in familial CLL development...
  2. pmc Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection
    Etienne Patin
    Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Necker Medical School, INSERM Unité 980, Paris, France
    Gastroenterology 143:1244-52.e1-12. 2012
    ..Only a fraction of patients with chronic HCV infection develop liver fibrosis, a process that might also be affected by genetic factors. We performed a 2-stage GWA study of liver fibrosis progression related to HCV infection...
  3. pmc Impact of IL28B, APOH and ITPA Polymorphisms on Efficacy and Safety of TVR- or BOC-Based Triple Therapy in Treatment-Experienced HCV-1 Patients with Compensated Cirrhosis from the ANRS CO20-CUPIC Study
    Frédégonde About
    Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale INSERM U1163, Paris, France
    PLoS ONE 10:e0145105. 2015
    ..We explored the role of IL28B, APOH and ITPA SNPs on the outcomes of triple therapy including telaprevir or boceprevir in patients with compensated cirrhosis chronically infected with HCV-1...
  4. doi request reprint A new 3p25 locus is associated with liver fibrosis progression in human immunodeficiency virus/hepatitis C virus-coinfected patients
    Damien Ulveling
    Equipe Genomique, Bioinformatique et Applications EA4627, Chaire de Bioinformatique, Conservatoire National des Arts et Metiers, Paris, France
    Hepatology 64:1462-1472. 2016
    ..The second signal, obtained with rs11790131 (P = 9.3 × 10-9 ) on chromosome region 9p22, was not replicated...
  5. pmc Combined linkage and association studies show that HLA class II variants control levels of antibodies against Epstein-Barr virus antigens
    Vincent Pedergnana
    Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Sante et de la Recherche Medicale, Paris, France University Paris Descartes, Sorbonne Paris Cité, Imagine Institute, Paris, France
    PLoS ONE 9:e102501. 2014
    ..02). In summary, this study shows that HLA class II variants influenced anti-EBNA-1 IgG titers in a European population. It further shows the role of the same variants in the risk of HL...
  6. pmc Analysis of IL28B variants in an Egyptian population defines the 20 kilobases minimal region involved in spontaneous clearance of hepatitis C virus
    Vincent Pedergnana
    Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale U980, Paris, France
    PLoS ONE 7:e38578. 2012
    ..HCV clearance in Egypt was associated with a region of IL28B smaller than that identified in European populations, and involved the non-synonymous IL28B SNP, rs8103142...
  7. ncbi request reprint FAS promoter polymorphisms correlate with activity grade in hepatitis C patients
    Dorian McIlroy
    Laboratoire d Immunologie Cellulaire et Tissulaire bService de Gastroentérologie, Hopital Pitie Salpetriere, Paris, France
    Eur J Gastroenterol Hepatol 17:1081-8. 2005
    ..Hepatocytes are susceptible to FAS-mediated apoptosis. The impact of polymorphisms in the FAS gene on histopathological features of HCV infection was therefore investigated...
  8. doi request reprint Genomewide association study of a rapid progression cohort identifies new susceptibility alleles for AIDS (ANRS Genomewide Association Study 03)
    Sigrid Le Clerc
    Conservatoire National des Arts et Metiers, Paris, France
    J Infect Dis 200:1194-201. 2009
    ..The discovery of genetic factors that predispose individuals to rapid progression to AIDS should also reveal new insights into the molecular etiology of the pathology...
  9. ncbi request reprint Deleterious genetic influence of CX3CR1 genotypes on HIV-1 disease progression
    Sophie Faure
    INSERM U543, Hopital Salpetriere, Paris, France
    J Acquir Immune Defic Syndr 32:335-7. 2003
    ..These results may explain the conflicting results published on the impact of CX3CR1 polymorphism in seroconverters...
  10. doi request reprint Genomewide association study of an AIDS-nonprogression cohort emphasizes the role played by HLA genes (ANRS Genomewide Association Study 02)
    Sophie Limou
    Conservatoire National des Arts et Metiers, Universite Paris 7, Paris, France
    J Infect Dis 199:419-26. 2009
    ..The present study, the first GWAS of HIV-1 nonprogressors, underscores the potential for some HLA genes to control disease progression soon after infection...
  11. pmc CCR5Delta32 protein expression and stability are critical for resistance to human immunodeficiency virus type 1 in vivo
    Lokesh Agrawal
    Indiana University School of Medicine, Department of Microbiology and Immunology, 635 Barnhill Drive, Room 420, Indianapolis, IN 46202, USA
    J Virol 81:8041-9. 2007
    ..The results also suggest that other cellular or virally induced factors may be involved in the stability of CCR5Delta32 protein...
  12. doi request reprint Identification of the CCR5-Delta32 HIV resistance allele and new mutations of the CCR5 gene in different Tunisian populations
    Asma Jlizi
    Laboratoire de Genetique, Immunologie et Pathologies Humaines, Faculte des Sciences de Tunis, Universite Tunis El Manar, Tunis, Tunisie
    Hum Immunol 68:993-1000. 2007
    ..The frequency of the CCR5-Delta32 variant was significantly different between the two groups, leading us to conclude that this mutation might confer protection against HIV infection in Tunisian populations...
  13. pmc A triple-mutated allele of granzyme B incapable of inducing apoptosis
    Dorian McIlroy
    Laboratoire d Immunologie Cellulaire et Tissulaire, Institut National de la Sante et de la Recherche Medicale U543, Faculté de Médecine Pitié Salpêtrière, 75013 Paris, France
    Proc Natl Acad Sci U S A 100:2562-7. 2003
    ....