Patrick Ritz

Summary

Country: France

Publications

  1. ncbi request reprint Pharmacokinetics and drug toxicity in elderly patients: a case for geriatric core data in clinical trials
    P Ritz
    INSERM UMR 694, Angers, France
    J Nutr Health Aging 11:261-4. 2007
  2. doi request reprint Benefits and risks of bariatric surgery in patients aged more than 60 years
    Patrick Ritz
    Centre Intégré Obésité, Endocrinology Metabolism and Nutrition Department, CHU Toulouse, France USMR 1027 Inserm Université Paul Sabatier, CHU Toulouse, France Electronic address
    Surg Obes Relat Dis . 2014
  3. doi request reprint Usefulness of acarbose and dietary modifications to limit glycemic variability following Roux-en-Y gastric bypass as assessed by continuous glucose monitoring
    Patrick Ritz
    Nutrition Unit, Cardiovascular and Metabolism Division, CHU of Toulouse, Hospital Larrey, Toulouse Cedex 09, France
    Diabetes Technol Ther 14:736-40. 2012
  4. doi request reprint Gastric bypass is not associated with protein malnutrition in morbidly obese patients
    Patrick Ritz
    INSERM UMR 694, Angers, France
    Obes Surg 19:840-4. 2009
  5. doi request reprint Influence of gender and body composition on hydration and body water spaces
    P Ritz
    CHU, Pôle de maladies métaboliques et médecine interne, 4 rue Larrey, 49033 Angers, France
    Clin Nutr 27:740-6. 2008
  6. ncbi request reprint Hormonal regulation of mitochondrial energy production
    Patrick Ritz
    INSERM UMR 694, Angers, France
    Curr Opin Clin Nutr Metab Care 8:415-8. 2005
  7. ncbi request reprint Nutritional risk score is not sensitive enough to predict weight loss in diseased elderly subjects
    P Ritz
    Department of Geriatrics, Inserm UMR694
    J Nutr Health Aging 11:389-92. 2007
  8. ncbi request reprint Effects of changes in water compartments on physiology and metabolism
    P Ritz
    INSERM EMI U 00 18, CHU Angers, France
    Eur J Clin Nutr 57:S2-5. 2003
  9. ncbi request reprint Mitochondrial function, energy expenditure, aging and insulin resistance
    P Ritz
    INSERM UMR 694, Pôle médecine interne et maladies métaboliques, Angers, France
    Diabetes Metab 31:5S67-5S73. 2005
  10. ncbi request reprint Comparison of different methods to assess body composition of weight loss in obese and diabetic patients
    P Ritz
    INSERM UMR 694, Angers, France
    Diabetes Res Clin Pract 77:405-11. 2007

Collaborators

Detail Information

Publications58

  1. ncbi request reprint Pharmacokinetics and drug toxicity in elderly patients: a case for geriatric core data in clinical trials
    P Ritz
    INSERM UMR 694, Angers, France
    J Nutr Health Aging 11:261-4. 2007
    ..They are named geriatric core data and should be collected in each trial...
  2. doi request reprint Benefits and risks of bariatric surgery in patients aged more than 60 years
    Patrick Ritz
    Centre Intégré Obésité, Endocrinology Metabolism and Nutrition Department, CHU Toulouse, France USMR 1027 Inserm Université Paul Sabatier, CHU Toulouse, France Electronic address
    Surg Obes Relat Dis . 2014
    ..The benefits and risks of bariatric surgery are debated in older patients. The objective of this study was to compare the weight changes and adverse outcomes in patients>60 years and in younger ones...
  3. doi request reprint Usefulness of acarbose and dietary modifications to limit glycemic variability following Roux-en-Y gastric bypass as assessed by continuous glucose monitoring
    Patrick Ritz
    Nutrition Unit, Cardiovascular and Metabolism Division, CHU of Toulouse, Hospital Larrey, Toulouse Cedex 09, France
    Diabetes Technol Ther 14:736-40. 2012
    ..The aim of this study was to evaluate the effect of treatment with dietary counseling plus acarbose administration on the symptoms and on the characteristics of the CGM profile...
  4. doi request reprint Gastric bypass is not associated with protein malnutrition in morbidly obese patients
    Patrick Ritz
    INSERM UMR 694, Angers, France
    Obes Surg 19:840-4. 2009
    ..Patients undergoing bariatric surgery with a gastric bypass lose about 66% of excess weight. Although this procedure induces weight loss, it is unknown whether it leads to protein malnutrition, which is studied here...
  5. doi request reprint Influence of gender and body composition on hydration and body water spaces
    P Ritz
    CHU, Pôle de maladies métaboliques et médecine interne, 4 rue Larrey, 49033 Angers, France
    Clin Nutr 27:740-6. 2008
    ..Two indicators of cellular hydration (TBW over fat free mass, and ICW over fat free mass) were studied...
  6. ncbi request reprint Hormonal regulation of mitochondrial energy production
    Patrick Ritz
    INSERM UMR 694, Angers, France
    Curr Opin Clin Nutr Metab Care 8:415-8. 2005
    ..Furthermore, a mismatch between oxygen consumption and energy intake may not be sufficient to understand body weight regulation. It appears that the efficiency of adenosine triphosphate production may play a role...
  7. ncbi request reprint Nutritional risk score is not sensitive enough to predict weight loss in diseased elderly subjects
    P Ritz
    Department of Geriatrics, Inserm UMR694
    J Nutr Health Aging 11:389-92. 2007
    ..Among the tools proposed to define malnutrition and to screen persons at risk of malnutrition, the nutritional risk score (NRS) has been suggested as a simple tool...
  8. ncbi request reprint Effects of changes in water compartments on physiology and metabolism
    P Ritz
    INSERM EMI U 00 18, CHU Angers, France
    Eur J Clin Nutr 57:S2-5. 2003
    ..Further studies are therefore necessary to challenge the cell swelling theory. If confirmed, strategies to modify cellular hydration could be used to improve metabolic orientations especially in the critically ill...
  9. ncbi request reprint Mitochondrial function, energy expenditure, aging and insulin resistance
    P Ritz
    INSERM UMR 694, Pôle médecine interne et maladies métaboliques, Angers, France
    Diabetes Metab 31:5S67-5S73. 2005
    ..Aging and insulin resistance are other regulators of this ratio. Finally there is a rising body of evidence linking diabetes to mitochondrial functions...
  10. ncbi request reprint Comparison of different methods to assess body composition of weight loss in obese and diabetic patients
    P Ritz
    INSERM UMR 694, Angers, France
    Diabetes Res Clin Pract 77:405-11. 2007
    ..No effect of diabetes per se was observed. A 3- or 4-compartmental analysis is necessary to accurately estimate body composition and its changes during weight loss...
  11. ncbi request reprint Factors affecting energy and macronutrient requirements in elderly people
    P Ritz
    Service de Medecine B, Angers, France
    Public Health Nutr 4:561-8. 2001
    ....
  12. ncbi request reprint Bioelectrical impedance analysis estimation of water compartments in elderly diseased patients: the source study
    P Ritz
    Centre Hospitalier Universitaire, Angers, France
    J Gerontol A Biol Sci Med Sci 56:M344-8. 2001
    ..This study validates, in geriatric patients, bioelectrical impedance analysis (BIA) equations that had been derived to estimate total body water (TBW) and extracellular water (ECW) in healthy elderly subjects...
  13. pmc Kinetics and control of oxidative phosphorylation in rat liver mitochondria after dexamethasone treatment
    Damien Roussel
    Laboratoire de Biochimie et Biologie Moleculaire, INSERM EMI U 00 18, 4 rue Larrey, F 49033 Angers Cedex, France
    Biochem J 382:491-9. 2004
    ..They also provide a complete description of the effects of dexamethasone treatment on liver mitochondrial bioenergetics...
  14. pmc Mitochondrial energy metabolism in a model of undernutrition induced by dexamethasone
    Jean Francois Dumas
    Medecine B, CHU, F 49033 Angers cedex 01, France
    Br J Nutr 90:969-77. 2003
    ..In contrast, none of the variables of energy metabolism determined in gastrocnemius mitochondria was altered by DEX treatment. Therefore, it appears that DEX specifically affects mitochondrial energy metabolism in the liver...
  15. ncbi request reprint Food restriction affects energy metabolism in rat liver mitochondria
    Jean Francois Dumas
    INSERM EMI U 00 18, Laboratoire de Biochimie et de Biologie Moleculaire, Medecine B, CHU, F 49033 Angers cedex 01, France
    Biochim Biophys Acta 1670:126-31. 2004
    ..Therefore, it appears that rats not only adapt to food restriction through simple passive mechanisms, such as liver mass loss, but also through decreased mitochondrial energetic metabolism...
  16. doi request reprint Fatty liver and insulin resistance in obese Zucker rats: no role for mitochondrial dysfunction
    Mélissa Flamment
    INSERM, U694, CHU Angers, 4 rue Larrey, F 49033 Angers, France
    Biochimie 90:1407-13. 2008
    ..In conclusion, isolated liver mitochondria from lean and obese insulin-resistant Zucker rats showed strictly the same mitochondrial function. It remains to be elucidated whether adiponectin increase is involved in these results...
  17. ncbi request reprint Oral supplements differing in fat and carbohydrate content: effect on the appetite and food intake of undernourished elderly patients
    Miriam Ryan
    INSERM EMI U 00 18, France
    Clin Nutr 23:683-9. 2004
    ..This study compared the effect of isoenergetic (1050 kJ) high fat or high carbohydrate oral supplements, given at breakfast, on the short-term appetite and energy intake in undernourished elderly subjects...
  18. doi request reprint Cancer cachexia: measured and predicted resting energy expenditures for nutritional needs evaluation
    Gyasi Johnson
    Institut National de la Sante et de la Recherche Medicale, Unité 694, Université d Angers Laboratoire de biochimie et biologie moléculaire, Centre Hospitalier Universitaire, Angers, France
    Nutrition 24:443-50. 2008
    ..The present study evaluated the agreement between measured and predicted REE (mREE and pREE, respectively) and the influence of acute phase response (APR) on REE...
  19. ncbi request reprint Energy requirements are not greater in elderly patients suffering from pressure ulcers
    Bernd Dambach
    Department of Medicine, University Hospital of Angers, Angers, France
    J Am Geriatr Soc 53:478-82. 2005
    ..To estimate energy requirements in diseased elderly patients with pressure ulcers (PUs)...
  20. ncbi request reprint Adenine nucleotide translocator promotes oxidative phosphorylation and mild uncoupling in mitochondria after dexamethasone treatment
    Matthieu Arvier
    Institut National de la Sante et de la Recherche Medicale, Laboratoire de Biochimie et de Biologie Moleculaire, Centre Hospitalier Universitaire, Angers, France
    Am J Physiol Endocrinol Metab 293:E1320-4. 2007
    ..In conclusion, dexamethasone increases mitochondrial capacity to generate ATP by modifying ANT and ATP synthase. The side effect is an increased leak in nonphosphorylating conditions...
  21. ncbi request reprint Short-term effect of a protein load on appetite and food intake in diseased mildly undernourished elderly people
    Paul Irvine
    INSERM EMI U 00 18, Medicine B CHU, 4 rue Larrey, Angers F 49033, Cedex, France
    Clin Nutr 23:1146-52. 2004
    ..We have tested the hypothesis that a protein-rich supplement inhibits appetite and decreases voluntary food intake...
  22. doi request reprint Are elderly hospitalized patients getting enough protein?
    Cathy Gaillard
    Department of Metabolic Diseases and Internal Medicine, University Hospital of Angers, Angers, France
    J Am Geriatr Soc 56:1045-9. 2008
    ..To determine the protein requirements of elderly hospitalized patients...
  23. doi request reprint Weight loss is more sustained after biliopancreatic diversion with duodenal switch than Roux-en-Y gastric bypass in superobese patients
    Philippe Topart
    Société de Chirurgie Viscérale, Clinique de l Anjou, Angers, France
    Surg Obes Relat Dis 9:526-30. 2013
    ..A total of 83 BPD-DS and 97 RYGB procedures were performed from March 2002 to October 2009 for an initial mean body mass index of 55 kg/m(2)...
  24. doi request reprint One-year weight loss after primary or revisional Roux-en-Y gastric bypass for failed adjustable gastric banding
    Philippe Topart
    Société de Chirurgie Viscérale, Clinique de l Anjou, Angers, France
    Surg Obes Relat Dis 5:459-62. 2009
    ..With a gastric banding failure rate of nearly 40% at 5 years, the need for revisional surgery is increasing. The effect of a failed previous bariatric surgery on the weight loss curve after RYGB is still a controversial issue...
  25. ncbi request reprint Underreporting of food intake in obese diabetic and nondiabetic patients
    Agnes Salle
    Diabetes and Nutrition Department, University Hospital of Angers, Angers, France
    Diabetes Care 29:2726-7. 2006
  26. doi request reprint Comparative early outcomes of three laparoscopic bariatric procedures: sleeve gastrectomy, Roux-en-Y gastric bypass, and biliopancreatic diversion with duodenal switch
    Philippe Topart
    Société de Chirurgie Viscérale, Clinique de l Anjou, Angers, France
    Surg Obes Relat Dis 8:250-4. 2012
    ....
  27. ncbi request reprint Energy requirements in hospitalized elderly people
    Emmanuel Alix
    Department of Geriatrics, General Hospital, Le Mans, France
    J Am Geriatr Soc 55:1085-9. 2007
    ..To estimate energy intake and energy expenditure (EE) in elderly hospitalized patients recovering from an acute illness...
  28. ncbi request reprint Dinitrophenol-induced mitochondrial uncoupling in vivo triggers respiratory adaptation in HepG2 cells
    Valerie Desquiret
    Department of Biochemistry and Molecular Biology, INSERM UMR 694, 4 rue Larrey, F 49033 Angers Cedex, France
    Biochim Biophys Acta 1757:21-30. 2006
    ....
  29. doi request reprint Early prediction of failure to lose weight after obesity surgery
    Patrick Ritz
    Department of Cardiovascular and Metabolic Diseases, CHU Toulouse, Toulouse, France
    Surg Obes Relat Dis 9:118-21. 2013
    ..Our objective was to report the criteria for an early prediction of the failure to lose enough weight in the setting of a private practice and an academic center of obesity surgery...
  30. doi request reprint Weight loss prior to bariatric surgery is not a pre-requisite of excess weight loss outcomes in obese patients
    Guillaume Becouarn
    Société de Chirurgie, Clinique de l Anjou, Angers, France
    Obes Surg 20:574-7. 2010
    ..Although weight loss before bariatric surgery may carry advantages during the surgical procedure (decreased liver volume, operation duration, and blood loss), it is still debated whether it induces a greater long-term weight loss...
  31. doi request reprint Should biliopancreatic diversion with duodenal switch be done as single-stage procedure in patients with BMI > or = 50 kg/m2?
    Philippe Topart
    Société de Chirurgie Viscérale, Clinique de l Anjou, Angers, France
    Surg Obes Relat Dis 6:59-63. 2010
    ..Controversy exists regarding the potentially increased risks of a single-stage procedure compared with the risks of sleeve gastrectomy first followed by the malabsorptive procedure after an initial weight loss...
  32. ncbi request reprint Biliopancreatic diversion with duodenal switch or gastric bypass for failed gastric banding: retrospective study from two institutions with preliminary results
    Philippe Topart
    Société de Chirurgie Viscérale, Clinique de l Anjou, Angers, France
    Surg Obes Relat Dis 3:521-5. 2007
    ....
  33. doi request reprint Usefulness of continuous glucose monitoring for the diagnosis of hypoglycemia after a gastric bypass in a patient previously treated for type 2 diabetes
    Hélène Hanaire
    Pôle Cardio Vasculaire et Métabolique, Service de Diabetologie, CHU Toulouse, Hopital Larrey, TSA 30030, 31059 Toulouse Cedex 9, France
    Obes Surg 20:126-9. 2010
    ..Because hypoglycemia can be difficult to diagnose from dumping syndrome, continuous glucose monitoring is a very useful tool revealing the episodes in free living circumstances and can be used to monitor the treatment success...
  34. doi request reprint Pouch size after gastric bypass does not correlate with weight loss outcome
    Philippe Topart
    Société de Chirurgie Viscérale, Clinique de l Anjou, Angers, France
    Obes Surg 21:1350-4. 2011
    ..Behavorial factors such as recurrent eating disorders and failure to adapt to the changes induced by the surgery may explain at least in part weight loss failure...
  35. ncbi request reprint Maternal smoking is associated with mitochondrial DNA depletion and respiratory chain complex III deficiency in placenta
    Natacha Bouhours-Nouet
    Institut National de la Santé et de la Recherche Médicale EMI U 00 18, Laboratory of Biochemistry and Molecular Biology, University Hospital of Angers, Angers, France
    Am J Physiol Endocrinol Metab 288:E171-7. 2005
    ..74, P < 0.01), a marker of fetal growth. These results show that maternal smoking is associated with placental mitochondrial dysfunction, which might contribute to restricted fetal growth by limiting energy availability in cells...
  36. ncbi request reprint A practical approach to estimate resting energy expenditure in frail elderly people
    C Gaillard
    Pôle de médecine interne et maladies métaboliques, Angers, France
    J Nutr Health Aging 12:277-80. 2008
    ..The aim of the present study was to assess the accuracy of those equations in sick elderly patients, using the Bland and Altman methods with our database of 187 REE measurements...
  37. ncbi request reprint Energy requirements in frail elderly people: a review of the literature
    C Gaillard
    Pôle de médecine interne et maladies métaboliques, Angers, France
    Clin Nutr 26:16-24. 2007
    ....
  38. ncbi request reprint Dexamethasone treatment specifically increases the basal proton conductance of rat liver mitochondria
    Damien Roussel
    Laboratoire de Biochimie et de Biologie Moleculaire, INSERM EMI U 00 18, Angers, France
    FEBS Lett 541:75-9. 2003
    ..This effect would have a modest impact on energy expenditure in rats...
  39. ncbi request reprint 'Glucose control-related' and 'non-glucose control-related' effects of insulin on weight gain in newly insulin-treated type 2 diabetic patients
    A Salle
    Inserm UMR694, CHU Angers, France
    Br J Nutr 94:931-7. 2005
    ..Therefore, in the initial 6 months, weight gain can be attributed to a 'glucose control-related effect' and further gain appears to be due to a 'non-glucose control-related' effect of insulin treatment...
  40. doi request reprint Glucose Profiles in Pregnant Women After a Gastric Bypass : Findings from Continuous Glucose Monitoring
    Camille Bonis
    Department of Diabetology, Metabolic Diseases, and Nutrition, CHU Toulouse, Toulouse, France
    Obes Surg 26:2150-5. 2016
    ..We aimed here at describing continuous glucose monitoring (CGM) profile of pregnant women after RYGB...
  41. doi request reprint Impact of Carbohydrate Content and Glycemic Load on Postprandial Glucose After Roux-en-Y Gastric Bypass
    Blandine Tramunt
    Department of Diabetology, Metabolic Diseases, and Nutrition, CHU Toulouse, Toulouse, France
    Obes Surg 26:1487-92. 2016
    ..Abnormal glucose profiles have been described after Roux-en-Y gastric bypass (RYGB) with intense postprandial hyperglycemic peaks in some but not all the patients. The underlying mechanisms of these anomalies are not totally understood...
  42. ncbi request reprint The importance of good hydration for day-to-day health
    Patrick Ritz
    Medecine B, Centre Hospitalier Universitaire, F 49033 Angers 01, France
    Nutr Rev 63:S6-13. 2005
    ..However, due to the lack of suitable tools for assessment of hydration status, the effects of hydration on other aspects of day-to-day health and well-being remain to be demonstrated...
  43. ncbi request reprint Chronic cellular dehydration in the aged patient
    P Ritz
    Centre Hospitalier Universitaire, Angers, France
    J Gerontol A Biol Sci Med Sci 56:M349-52. 2001
    ..The present study compared water spaces and cellular hydration in adults, healthy and diseased aged patients...
  44. ncbi request reprint Physiology of aging with respect to gastrointestinal, circulatory and immune system changes and their significance for energy and protein metabolism
    P Ritz
    Service de Medecine B, Centre Hospitalier Universitaire, Angers, France
    Eur J Clin Nutr 54:S21-5. 2000
    ..However, aging is associated with difficulties in adapting to new environmental conditions that lead to stress. Repeated episodes of stress might lead to accumulation of deficits that can affect energy and protein balances...
  45. ncbi request reprint Resting energy expenditure is not increased in mildly hyperglycaemic obese diabetic patients
    M Ryan
    Department of Diabetes and Nutrition, CHU, Angers, F 49033, France
    Br J Nutr 96:945-8. 2006
    ..We conclude that REE is not necessarily increased by the presence of diabetes in obese people...
  46. ncbi request reprint Body water spaces and cellular hydration during healthy aging
    P Ritz
    Service de Medecine B, Centre Hospitalier Universitaire, Angers, France
    Ann N Y Acad Sci 904:474-83. 2000
    ..The same finding holds for the proportion of intracellular water to fat-free mass. We conclude that hydration of fat-free mass and cellular hydration are not affected in healthy aging...
  47. ncbi request reprint Effect of insulin treatment on the body composition of Type 2 diabetic patients
    A Salle
    Department of Medicine and Inserm EMI U 00 18, CHU Angers, France
    Diabet Med 21:1298-303. 2004
    ..The composition of this weight gain is poorly understood. Predominant increases in fat mass could increase cardiovascular risks. The aim of the study was to evaluate insulin-induced body composition changes...
  48. doi request reprint Is skeletal muscle mitochondrial dysfunction a cause or an indirect consequence of insulin resistance in humans?
    J F Dumas
    INSERM U694, 49033 Angers, France
    Diabetes Metab 35:159-67. 2009
    ..Finally, we also consider whether or not these aberrations could be the cause of the development of the disease or whether mitochondrial dysfunction may simply be the consequence of an insulin-resistant state...
  49. ncbi request reprint Estimation of calorie and protein intake in aged patients: validation of a method based on meal portions consumed
    Gilles Berrut
    Unité de Gérontologie Clinique, Centre Hospitalier Universitaire, Angers, France
    J Gerontol A Biol Sci Med Sci 57:M52-6. 2002
    ..We performed three studies to investigate the meal-portion (MP) method as a tool for estimating calorie and protein intakes in clinical situations...
  50. ncbi request reprint Dexamethasone impairs muscle energetics, studied by (31)P NMR, in rats
    J F Dumas
    INSERM EMI U 00 18, Laboratoire de Biochimie et de Biologie Moleculaire, CHU, 4 rue Larrey, 49033 Angers Cedex, France
    Diabetologia 48:328-35. 2005
    ..Glucocorticoid treatments are associated with increased whole-body oxygen consumption. We hypothesised that an impairment of muscle energy metabolism can participate in this increased energy expenditure...
  51. doi request reprint The prevalence of abnormal eating behaviour in a representative sample of the French diabetic population
    M Ryan
    Pôle de maladies métaboliques et médecine interne, EDN CHU d Angers, 4, rue Larrey, 49033 Angers Cedex, France
    Diabetes Metab 34:581-6. 2008
    ..To assess the relationship between abnormal eating behaviour (AEB) and diabetes in a sample of French adult patients with type 1 (T1D) and type 2 (T2D) diabetes...
  52. ncbi request reprint Effect of equilibrated hydration changes on total body water estimates by bioelectrical impedance analysis
    Vincent Pialoux
    Laboratoire de Physiologie Biologie du Sport, Faculte de Medecine, Universite d Auvergne, 28 Place Henri Dunant, Clermont Ferrand 63000, France
    Br J Nutr 91:153-9. 2004
    ..However, it is not a valid technique for assessing FM and FFM under these conditions...
  53. ncbi request reprint Is a failure to recognize an increase in food intake a key to understanding insulin-induced weight gain?
    Miriam Ryan
    Department of Diabetes and Nutrition, CHU Angers F 49033, France
    Diabetes Care 31:448-50. 2008
    ..However, it is not being recognized because of significant underestimation of self-reported food intake, which appears to be associated with increased dietary restraint...
  54. ncbi request reprint Influence of intensity of food restriction on skeletal muscle mitochondrial energy metabolism in rats
    Gyasi Johnson
    Institut National de la Sante et de la Recherche Medicale, Unité 694, Universite d Angers, F 49033 Angers cedex 01, France
    Am J Physiol Endocrinol Metab 291:E460-7. 2006
    ..Our study highlights an early step in mitochondrial adaptation to FR and the influence of the severity of restriction on this adaptation. This step may be involved in an aging-retardation process...
  55. ncbi request reprint Muscle fat oxidative capacity is not impaired by age but by physical inactivity: association with insulin sensitivity
    Virginie Rimbert
    Protein and Energy Metabolism Research Unit, Auvergne University, Human Nutrition Research Centre of Auvergne, Clermont Ferrand, France
    FASEB J 18:737-9. 2004
    ..79, P<0.01). We concluded that mitochondrial functions, OXFA and ISI, are not impaired by age but by physical inactivity and are closely correlated...
  56. doi request reprint The effect of an incremental increase in exercise on appetite, eating behaviour and energy balance in lean men and women feeding ad libitum
    Stephen Whybrow
    The Rowett Research Institute, Greenburn Road, Aberdeen AB21 9SB, UK
    Br J Nutr 100:1109-15. 2008
    ..However, the degree of compensation varied considerably among individuals. The present study captured the initial compensation in EI for exercise-induced energy deficits. Total compensation would take a matter of weeks...
  57. doi request reprint Mitochondrial effects of dexamethasone imply both membrane and cytosolic-initiated pathways in HepG2 cells
    Valerie Desquiret
    INSERM, U694, Angers F 49033, France
    Int J Biochem Cell Biol 40:1629-41. 2008
    ..We concluded that mitochondria are the target of multiple dexamethasone-induced regulatory pathways that are set up gradually after the beginning of hormone exposure and that durably influence mitochondrial oxidative phosphorylation...
  58. ncbi request reprint Thyroxine therapy in euthyroid patients does not affect body composition or muscular function
    Séverine Dubois
    Pôle de maladies métaboliques et médecine interne Centre Hospitalier Universitaire d Angers, Angers Cedex 01, France
    Thyroid 18:13-9. 2008
    ..The secondary objective was to assess the effect of the therapy on energy expenditure and muscular function...