- The ordered transmission disequilibrium test: detection of modifier genesHervé Perdry
INSERM U535, BP 1000, F 94817 Villejuif, France
Genet Epidemiol 33:1-5. 2009..We investigate the power of the method by simulations under various genetic models and covariate distributions and compare it with a linear regression analysis...
- Modeling the effect of susceptibility factors (HLA and PTPN22) in rheumatoid arthritisHervé Perdry
INSERM U535, Universite Paris Sud, Paris, France
Methods Mol Biol 713:201-14. 2011..BMC Proc 1 (Suppl 1):S37, 2007) show that observed data is not explained by a single variant as initially reported and that using the information on 3 SNPs discriminates the genotypic relative risks (GRRs) from 1 to 4.7...
- An ordered subset approach to including covariates in the transmission disequilibrium testHervé Perdry
INSERM U535, BP 1000, Villejuif, 94817, France
BMC Proc 1:S77. 2007..For a third locus, detectable by the classical transmission-disequilibrium test, a substantial increase of power of detection is shown...