Cedric Moro

Summary

Country: France

Publications

  1. ncbi Atrial natriuretic peptide stimulates lipid mobilization during repeated bouts of endurance exercise
    Cedric Moro
    Franco Czech Laboratory for Clinical Research on Obesity, French Institute of Health and Medical Research INSERM U586, Toulouse, France
    Am J Physiol Endocrinol Metab 290:E864-9. 2006
  2. ncbi Cardiovascular and metabolic effects of natriuretic peptides
    Cedric Moro
    Department of Medical and Clinical Pharmacology, Faculty of Medicine, Toulouse, France
    Fundam Clin Pharmacol 20:41-9. 2006
  3. ncbi [Physiological and pathophysiological features of the control of lipolysis and lipid mobilization by natriuretic peptides]
    Cedric Moro
    INSERM, U586, Unité de Recherche sur les Obésités, F 31432 Toulouse
    J Soc Biol 200:67-76. 2006
  4. ncbi Atrial natriuretic peptide contributes to physiological control of lipid mobilization in humans
    Cedric Moro
    Unité de Recherches sur les Obésités, Institut National de la Santé et de la Recherche Médicale U586, Toulouse, France
    FASEB J 18:908-10. 2004
  5. ncbi Atrial natriuretic peptide contribution to lipid mobilization and utilization during head-down bed rest in humans
    Cedric Moro
    Institut National de la Sante et de la Recherche Medicale, U858, Laboratoire de Recherche sur les Obésités, Toulouse, France
    Am J Physiol Regul Integr Comp Physiol 293:R612-7. 2007
  6. ncbi Training enhances ANP lipid-mobilizing action in adipose tissue of overweight men
    Cedric Moro
    Franco Czech Laboratory for Clinical Research on Obesity, INSERM U586, Institut Louis Bugnard, Centre Hospitalier Universitaire de Toulouse, Universite Paul Sabatier, Toulouse, France
    Med Sci Sports Exerc 37:1126-32. 2005
  7. pmc Perilipin 5 fine-tunes lipid oxidation to metabolic demand and protects against lipotoxicity in skeletal muscle
    Claire Laurens
    INSERM, UMR1048, Institute of Metabolic and Cardiovascular Diseases, Toulouse, France
    Sci Rep 6:38310. 2016
  8. doi Defective Natriuretic Peptide Receptor Signaling in Skeletal Muscle Links Obesity to Type 2 Diabetes
    Marine Coué
    Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases, INSERM, UMR1048, Toulouse, France University of Toulouse, UMR1048, Paul Sabatier University, Toulouse, France
    Diabetes 64:4033-45. 2015
  9. doi Natriuretic peptides and fat metabolism
    Cedric Moro
    aINSERM, UMR1048, Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases I2MC bUMR1048, Paul Sabatier University, Toulouse, France
    Curr Opin Clin Nutr Metab Care 16:645-9. 2013
  10. ncbi Functional and pharmacological characterization of the natriuretic peptide-dependent lipolytic pathway in human fat cells
    Cedric Moro
    Unité de Recherches sur les Obésités, Institut National de la Sante et de la Recherche Medicale, Universitaire Rangueil, Toulouse, France
    J Pharmacol Exp Ther 308:984-92. 2004

Collaborators

Detail Information

Publications17

  1. ncbi Atrial natriuretic peptide stimulates lipid mobilization during repeated bouts of endurance exercise
    Cedric Moro
    Franco Czech Laboratory for Clinical Research on Obesity, French Institute of Health and Medical Research INSERM U586, Toulouse, France
    Am J Physiol Endocrinol Metab 290:E864-9. 2006
    ..The results suggest that ANP is involved in the control of lipolysis during exercise and that it contributes to stimulation of lipolysis during repeated bouts of exercise...
  2. ncbi Cardiovascular and metabolic effects of natriuretic peptides
    Cedric Moro
    Department of Medical and Clinical Pharmacology, Faculty of Medicine, Toulouse, France
    Fundam Clin Pharmacol 20:41-9. 2006
    ..This review will briefly describe the effects of NP on the cardiovascular system and lipid metabolism...
  3. ncbi [Physiological and pathophysiological features of the control of lipolysis and lipid mobilization by natriuretic peptides]
    Cedric Moro
    INSERM, U586, Unité de Recherche sur les Obésités, F 31432 Toulouse
    J Soc Biol 200:67-76. 2006
    ..The molecular basis of this inverse correlation is not yet demonstrated from a functional standpoint. Further studies are needed to clearly define the pathophysiological role of NP in obesity and heart failure...
  4. ncbi Atrial natriuretic peptide contributes to physiological control of lipid mobilization in humans
    Cedric Moro
    Unité de Recherches sur les Obésités, Institut National de la Santé et de la Recherche Médicale U586, Toulouse, France
    FASEB J 18:908-10. 2004
    ..Oral beta-adrenergic receptor blockade, which potentiates exercise-induced ANP release by the heart, may contribute to lipid mobilization in SCAT. The potential relevance of an ANP-related lipid-mobilizing pathway is discussed...
  5. ncbi Atrial natriuretic peptide contribution to lipid mobilization and utilization during head-down bed rest in humans
    Cedric Moro
    Institut National de la Sante et de la Recherche Medicale, U858, Laboratoire de Recherche sur les Obésités, Toulouse, France
    Am J Physiol Regul Integr Comp Physiol 293:R612-7. 2007
    ..In this physiological setting, independent of increasing catecholamines, our study suggests that ANP contributes to lipid mobilization and oxidation in healthy young men...
  6. ncbi Training enhances ANP lipid-mobilizing action in adipose tissue of overweight men
    Cedric Moro
    Franco Czech Laboratory for Clinical Research on Obesity, INSERM U586, Institut Louis Bugnard, Centre Hospitalier Universitaire de Toulouse, Universite Paul Sabatier, Toulouse, France
    Med Sci Sports Exerc 37:1126-32. 2005
    ....
  7. pmc Perilipin 5 fine-tunes lipid oxidation to metabolic demand and protects against lipotoxicity in skeletal muscle
    Claire Laurens
    INSERM, UMR1048, Institute of Metabolic and Cardiovascular Diseases, Toulouse, France
    Sci Rep 6:38310. 2016
    ..These data highlight a key role of PLIN5 in LD function, first by finely adjusting LD FA supply to mitochondrial oxidation, and second acting as a protective factor against lipotoxicity in skeletal muscle...
  8. doi Defective Natriuretic Peptide Receptor Signaling in Skeletal Muscle Links Obesity to Type 2 Diabetes
    Marine Coué
    Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases, INSERM, UMR1048, Toulouse, France University of Toulouse, UMR1048, Paul Sabatier University, Toulouse, France
    Diabetes 64:4033-45. 2015
    ..Collectively, our data show that activation of NPRA signaling in skeletal muscle is important for the maintenance of long-term insulin sensitivity and has the potential to treat obesity-related metabolic disorders. ..
  9. doi Natriuretic peptides and fat metabolism
    Cedric Moro
    aINSERM, UMR1048, Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases I2MC bUMR1048, Paul Sabatier University, Toulouse, France
    Curr Opin Clin Nutr Metab Care 16:645-9. 2013
    ..Cardiac natriuretic peptides have emerged as potent metabolic hormones during the past decade. We here discuss recent work highlighting the potential importance of these hormones in metabolic physiology and diseases...
  10. ncbi Functional and pharmacological characterization of the natriuretic peptide-dependent lipolytic pathway in human fat cells
    Cedric Moro
    Unité de Recherches sur les Obésités, Institut National de la Sante et de la Recherche Medicale, Universitaire Rangueil, Toulouse, France
    J Pharmacol Exp Ther 308:984-92. 2004
    ..They are unaffected by insulin pretreatments of fat cells but undergo desensitization. In the search of potent and specific natriuretic peptide receptor-A antagonist, in the human fat cell, A71915 was the only reliable one found...
  11. pmc G0/G1 Switch Gene 2 controls adipose triglyceride lipase activity and lipid metabolism in skeletal muscle
    Claire Laurens
    INSERM, UMR1048, Institute of Metabolic and Cardiovascular Diseases, Toulouse, France University of Toulouse, Paul Sabatier University, France
    Mol Metab 5:527-37. 2016
    ..We here investigated the role of the protein G0/G1 Switch Gene 2 (G0S2), recently described as an inhibitor of ATGL in white adipose tissue, in the regulation of lipolysis and oxidative metabolism in skeletal muscle...
  12. doi Natriuretic peptides and cGMP signaling control of energy homeostasis
    Cedric Moro
    Institut National de la Santé et de la Recherche Médicale UPS UMR 1048 I2MC Institute of Metabolic and Cardiovascular Diseases, Toulouse, France
    Am J Physiol Heart Circ Physiol 304:H358-68. 2013
    ..e., white and brown adipose tissues, skeletal muscle, liver, and pancreas). These recent results on NPs are opening a new chapter into the physiological properties and therapeutic usefulness of this family of hormones...
  13. doi Fatty acids from fat cell lipolysis do not activate an inflammatory response but are stored as triacylglycerols in adipose tissue macrophages
    Sylvie Caspar-Bauguil
    INSERM, UMR1048, Institute of Metabolic and Cardiovascular Diseases, I2MC, Obesity Research Laboratory, Team 4, CHU Rangueil, 1 avenue Jean Poulhes, BP 84225, 31432, Toulouse Cedex 4, France
    Diabetologia 58:2627-36. 2015
    ..Here, we investigated the effects of FAs released during adipocyte lipolysis on AT macrophages (ATMs)...
  14. doi Immune cell Toll-like receptor 4 mediates the development of obesity- and endotoxemia-associated adipose tissue fibrosis
    Isabelle K Vila
    Franco Czech Laboratory for Clinical Research on Obesity, INSERM, 31432 Toulouse Cedex 4, France Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases, UMR1048, INSERM, 31432 Toulouse Cedex 4, France UMR1048, Paul Sabatier University, University of Toulouse, 31432 Toulouse Cedex 4, France
    Cell Rep 7:1116-29. 2014
    ..Together, these results indicate that obesity and endotoxemia favor the development of adipose tissue fibrosis, a condition associated with insulin resistance, through immune cell Toll-like receptor 4...
  15. pmc Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass
    Amandine Girousse
    INSERM, UMR1048, Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases, Toulouse, France University of Toulouse, UMR1048, Paul Sabatier University, France
    PLoS Biol 11:e1001485. 2013
    ..Thus, reduction in WAT lipolysis reshapes FA fluxes without increase of fat mass and improves glucose metabolism through cell-autonomous induction of fat cell de novo lipogenesis, which contributes to improved insulin sensitivity...
  16. doi Natriuretic peptide control of energy balance and glucose homeostasis
    Marine Coué
    Inserm UMR1048, Institute of Metabolic and Cardiovascular Diseases, Obesity Research Laboratory, Toulouse, France Paul Sabatier University, Toulouse, France
    Biochimie 124:84-91. 2016
    ..This review will focus on recent human and mouse studies to highlight the metabolic roles of NP and their potential relevance in the context of obesity and type 2 diabetes. ..
  17. doi Dynamics of skeletal muscle lipid pools
    Pierre Marie Badin
    Obesity Research Laboratory, Institut National de la Santé et de la Recherche Médicale INSERM Unité Mixte de Recherche UMR 1048, Institute of Metabolic and Cardiovascular Diseases I2MC, Toulouse, France University of Toulouse, UMR1048, Paul Sabatier University, Toulouse, France
    Trends Endocrinol Metab 24:607-15. 2013
    ..Thus, understanding the factors that control IMTG dynamics is crucial. Here we discuss recent literature describing the regulation of IMTG pools with a particular emphasis on lipases and lipid droplet (LD)-associated proteins. ..