- Increased HDL cholesterol and apoA-I in humans and mice treated with a novel SR-BI inhibitorDavid Masson
Division of Molecular Medicine, Department of Medicine, Columbia University, New York, USA
Arterioscler Thromb Vasc Biol 29:2054-60. 2009..Increasing HDL levels is a potential strategy for the treatment of atherosclerosis...
- Reduced VLDL clearance in Apoe(-/-)Npc1(-/-) mice is associated with increased Pcsk9 and Idol expression and decreased hepatic LDL-receptor levelsMinako Ishibashi
Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY, USA
J Lipid Res 51:2655-63. 2010..In contrast to modest induction of hepatic IDOL with synthetic LXR ligands, a striking upregulation of IDOL in Apoe(-/-)Npc1(-/-) mice could indicate a role of endogenous LXR ligands in regulation of hepatic IDOL...