Jacques Lepercq

Summary

Country: France

Publications

  1. ncbi [Perinatal complications in infants of women with diabetes mellitus]
    J Lepercq
    Service de Gynecologie Obstetrique, Groupe Hospitalier Cochin Saint Vincent De Paul, 82, avenue Denfert Rochereau 75674, Paris Cedex 14, France
    Arch Pediatr 12:763-5. 2005
  2. ncbi Leptin: a potential marker of placental insufficiency
    Jacques Lepercq
    Service de Gynecologie Obstetrique, Hopital Cochin Saint Vincent de Paul, Paris, France
    Gynecol Obstet Invest 55:151-5. 2003
  3. ncbi [Is there a standard biological screening of gestational diabetes mellitus?]
    J Lepercq
    Service de Gynecologie Obstetrique, Groupe Hospitalier Cochin Saint Vincent De Paul, Paris, France
    Gynecol Obstet Fertil 32:549-55. 2004
  4. ncbi Fetal macrosomia and maternal weight gain during pregnancy
    J Lepercq
    Service de Gynecologie Obstetrique, Hopital Cochin, Saint Vincent de Paul, AP HP, Universite Paris V, France
    Diabetes Metab 28:323-8. 2002
  5. ncbi Factors associated with preterm delivery in women with type 1 diabetes: a cohort study
    Jacques Lepercq
    Service de Gynecologie Obstetrique, Hopital Cochin, Saint Vincent de Paul, AP HP, 82, avenue Denfert Rochereau, 75674 Paris Cedex 14, France
    Diabetes Care 27:2824-8. 2004
  6. ncbi [Leptin during pregnancy]
    J Lepercq
    Service de Gynecologie Obstetrique, Hopital Cochin Saint Vincent de Paul, 82, avenue Denfert Rochereau, 75014 Paris, France
    J Gynecol Obstet Biol Reprod (Paris) 31:167-72. 2002
  7. ncbi Heterogeneity of fetal growth in type 1 diabetic pregnancy
    J Lepercq
    Department of Obstetrics and Gynecology, Cochin Saint Vincent de Paul Hospital, Paris
    Diabetes Metab 27:339-44. 2001
  8. ncbi Prenatal leptin production: evidence that fetal adipose tissue produces leptin
    J Lepercq
    Service de Gynecologie Obstetrique, Hopital Cochin Saint Vincent de Paul, 75674 Paris, France
    J Clin Endocrinol Metab 86:2409-13. 2001
  9. ncbi [The diabetic pregnant woman]
    J Lepercq
    Service de Gynecologie Obstetrique, Hopital Saint Vincent de Paul, F 75674 Paris cedex 14
    Ann Endocrinol (Paris) 64:S7-11. 2003
  10. doi Factors associated with cesarean delivery in nulliparous women with type 1 diabetes
    Jacques Lepercq
    Service de Gynecologie Obstetrique, Service de Diabetologie, Groupe Hospitalier Cochin Saint Vincent De Paul, AP HP, Universite Paris Descartes, Paris, France
    Obstet Gynecol 115:1014-20. 2010

Collaborators

Detail Information

Publications38

  1. ncbi [Perinatal complications in infants of women with diabetes mellitus]
    J Lepercq
    Service de Gynecologie Obstetrique, Groupe Hospitalier Cochin Saint Vincent De Paul, 82, avenue Denfert Rochereau 75674, Paris Cedex 14, France
    Arch Pediatr 12:763-5. 2005
  2. ncbi Leptin: a potential marker of placental insufficiency
    Jacques Lepercq
    Service de Gynecologie Obstetrique, Hopital Cochin Saint Vincent de Paul, Paris, France
    Gynecol Obstet Invest 55:151-5. 2003
    ..60). These data demonstrate that placental insufficiency is associated with a dramatic increase in placental leptin production. This results in a rise in maternal leptinemia that may be taken as an early index of placental dysfunction...
  3. ncbi [Is there a standard biological screening of gestational diabetes mellitus?]
    J Lepercq
    Service de Gynecologie Obstetrique, Groupe Hospitalier Cochin Saint Vincent De Paul, Paris, France
    Gynecol Obstet Fertil 32:549-55. 2004
    ..The actual proposed glucose threshold values for GDM are, respectively, 1.05 and 1.55-1.60 g/l for fasting and 2 h...
  4. ncbi Fetal macrosomia and maternal weight gain during pregnancy
    J Lepercq
    Service de Gynecologie Obstetrique, Hopital Cochin, Saint Vincent de Paul, AP HP, Universite Paris V, France
    Diabetes Metab 28:323-8. 2002
    ..To calculate an adjusted maternal weight gain during pregnancy including infant and placental weights to the actual weight gain and secondarily examine its influence on the occurrence of fetal macrosomia...
  5. ncbi Factors associated with preterm delivery in women with type 1 diabetes: a cohort study
    Jacques Lepercq
    Service de Gynecologie Obstetrique, Hopital Cochin, Saint Vincent de Paul, AP HP, 82, avenue Denfert Rochereau, 75674 Paris Cedex 14, France
    Diabetes Care 27:2824-8. 2004
    ..The reported rate of preterm delivery in women with type 1 diabetes ranges from 22 to 45%, but the reasons are unclear. The purpose of this study was to identify factors associated with preterm delivery in these women...
  6. ncbi [Leptin during pregnancy]
    J Lepercq
    Service de Gynecologie Obstetrique, Hopital Cochin Saint Vincent de Paul, 82, avenue Denfert Rochereau, 75014 Paris, France
    J Gynecol Obstet Biol Reprod (Paris) 31:167-72. 2002
    ..Leptin, the protein encoded by the Ob gene in the adipose cell, is produced by the placenta during pregnancy. This review describes recent findings regarding the putative functions of leptin during pregnancy...
  7. ncbi Heterogeneity of fetal growth in type 1 diabetic pregnancy
    J Lepercq
    Department of Obstetrics and Gynecology, Cochin Saint Vincent de Paul Hospital, Paris
    Diabetes Metab 27:339-44. 2001
    ..To investigate the frequency of macrosomia in an homogeneous cohort of type 1 diabetic mothers and to analyze the influence of maternal factors and glycemic control on the incidence of fetal macrosomia...
  8. ncbi Prenatal leptin production: evidence that fetal adipose tissue produces leptin
    J Lepercq
    Service de Gynecologie Obstetrique, Hopital Cochin Saint Vincent de Paul, 75674 Paris, France
    J Clin Endocrinol Metab 86:2409-13. 2001
    ..By contrast, placental leptin production makes a substantial contribution to maternal circulating leptin levels during pregnancy...
  9. ncbi [The diabetic pregnant woman]
    J Lepercq
    Service de Gynecologie Obstetrique, Hopital Saint Vincent de Paul, F 75674 Paris cedex 14
    Ann Endocrinol (Paris) 64:S7-11. 2003
    ..As well as for a diabetic pregnancy, the therapeutic management of GDM must be instituted early and must be intensive in order to reduce the level of fetal macrosomia to the one of the non-diabetic population...
  10. doi Factors associated with cesarean delivery in nulliparous women with type 1 diabetes
    Jacques Lepercq
    Service de Gynecologie Obstetrique, Service de Diabetologie, Groupe Hospitalier Cochin Saint Vincent De Paul, AP HP, Universite Paris Descartes, Paris, France
    Obstet Gynecol 115:1014-20. 2010
    ..To identify factors associated with cesarean delivery in nulliparous women with type 1 diabetes mellitus...
  11. ncbi [Obstetrical management of progestational diabetes mellitus]
    J Lepercq
    Service de Gynecologie Obstetrique, Hopital Cochin Saint Vincent de Paul, 82, avenue Denfert Rochereau, 75014 Paris, France
    J Gynecol Obstet Biol Reprod (Paris) 31:4S11-4S7. 2002
    ..Pre-conceptional programming and intensive collaborative follow-up of such pregnancies improve the outcome of such pregnancies...
  12. ncbi [Placental leptin and pregnancy pathologies]
    S Hauguel-de Mouzon
    , , 24, rue du Faubourg Saint-Jacques, 75014 Paris, France
    Gynecol Obstet Fertil 29:534-7. 2001
    ..The roles of fetal leptin and consequences of increased placental leptin production in pathological pregnancies have yet to be elucidated...
  13. ncbi Diagnosis and management of intrauterine growth retardation
    J Lepercq
    Service de Gynecologie Obstetrique, Hopital Saint Vincent de Paul, Paris, France
    Horm Res 49:14-9. 1998
    ..There is no medical treatment for IUGR. Early aspirin treatment reduces the incidence of IUGR in a high-risk population but should not be used routinely in all pregnant women...
  14. ncbi [Gestational diabetes mellitus cannot be simply restricted to hyperglycemia]
    J Lepercq
    Service de Gynecologie Obstetrique, Groupe Hospitalier Cochin Saint Vincent De Paul, 82, avenue Denfert Rochereau, 75674 Paris Cedex 14, France
    Gynecol Obstet Fertil 34:571-3. 2006
  15. ncbi [Indications and modalities of assisted reproductive techniques in infertile women with cystic fibrosis]
    S Epelboin
    Service de gynécologie obstétrique stérilité, Groupe Hospitalier Cochin Saint Vincent De Paul, 74 82, avenue Denfert Rochereau, 75014 Paris, France
    Gynecol Obstet Fertil 31:718-23. 2003
    ..To treat cystic fibrosis women who failed to conceive...
  16. ncbi Management and outcome of fetomaternal Rh alloimmunization in twin pregnancies
    J Lepercq
    Service de Gynecologie Obstetrique, Hopital Saint Vincent de Paul, Paris, France
    Fetal Diagn Ther 14:26-30. 1999
    ..The hemoglobin level was 13.2 (range 9.2-16.5) g/dl. Fetomaternal Rh alloimmunization in twin pregnancy is according to zygosity; each fetus has to be treated separately, except in case of transplacental communication...
  17. ncbi [Etiopathogeny of fetal macrosomia]
    J Lepercq
    Service de Gynecologie Obstetrique, Hopital Saint Vincent de Paul, AD HP, Universite Paris V
    J Gynecol Obstet Biol Reprod (Paris) 29:6-12. 2000
    ..Perinatal morbidity and long term consequences such as obesity and glucose intolerance might be associated with some of the factors leading to fetal overgrowth...
  18. doi Factors associated with urgent cesarean delivery in women with type 1 diabetes mellitus
    Grégoire Miailhe
    Department of Obstetrics and Gynecology, Port Royal, Paris, France
    Obstet Gynecol 121:983-9. 2013
    ..The objective of the present study was to identify factors associated with prelabor urgent cesarean delivery for fetal compromise in women with type 1 DM...
  19. doi Onset of autoimmune type 1 diabetes during pregnancy: Prevalence and outcomes
    Hélène Wucher
    Department of Immunology and Diabetology, Hopital Cochin, APHP, Universite Paris Descartes, France
    Best Pract Res Clin Endocrinol Metab 24:617-24. 2010
    ..We review these studies and discuss the links of autoimmune gestational diabetes with type 1 diabetes mellitus...
  20. ncbi A standardized protocol to achieve normoglycaemia during labour and delivery in women with type 1 diabetes
    J Lepercq
    Department of Obstetrics and Gynecology, AP HP, hospital Cochin Saint Vincent de Paul, Paris 5 University, 82, avenue Denfert Rochereau, 75674 Paris Cedex 14, France
    Diabetes Metab 34:33-7. 2008
    ..To evaluate a standardized protocol for maintaining near-normoglycaemia during labour and delivery in women with type 1 diabetes...
  21. ncbi Placental leptin receptor isoforms in normal and pathological pregnancies
    J Challier
    Universite P and M Curie, Physiopathologie de I Implantation et du Développement, 12 rue Cuvier, Paris, France
    Placenta 24:92-9. 2003
    ..The co-localization of leptin and the soluble receptor isoform suggests that this isoform serves for modulating maternal free leptin levels through modification of leptin binding capacities...
  22. doi Use of insulin glargine throughout pregnancy in 102 women with type 1 diabetes
    J Lepercq
    Service de Gynecologie Obstetrique, Hopital Cochin Saint Vincent de Paul, AP HP, 82, avenue Denfert Rochereau, 75674 Paris Cedex 14, France
    Diabetes Metab 36:209-12. 2010
    ..The aim of this study was to examine the safety of insulin glargine during pregnancy in women with type 1 diabetes mellitus (T1DM)...
  23. doi Outpatient cervical ripening by nitric oxide donors for prolonged pregnancy: a randomized controlled trial
    Thomas Schmitz
    Assistance Publique Hopitaux de Paris, Service de Gynecologie Obstetrique, Hopital Robert Debre, Hopital Bichat, Hopital Saint Antoine, and Hôpital Saint Vincent de Paul, Assistance Publique Hopitaux de Paris, Maternite Port Royal, Universite Paris Diderot, Universite Pierre et Marie Curie, Universite Rene Descartes, and INSERM UMR 1153 Equipe EPOPé, Paris, Assistance Publique Hopitaux de Paris, Hopital Bicetre, Service de Gynécologie Obstétrique and Université Paris Sud, Le Kremlin Bicetre, Hôpital Jeanne de Flandre and Université Lille 2, Lille, Hopital de Poissy Saint Germain, Département de gynécologie obstétrique, Poissy, Université Versailles Saint Quentin, Saint Quentin en Yvelines, CHU de Nantes, Hopital Mere Enfant, Service de Gynecologie Obstetrique, and Université de Nantes, Nantes, CHRU Bretonneau, centre Olympe de Gouges, and Université François Rabelais, Tours, and CHU de Rouen, Service de Gynecologie Obstetrique, and Université de Rouen, Japan
    Obstet Gynecol 124:1089-97. 2014
    ..To assess whether outpatient cervical ripening at 41 0/7 weeks of gestation with the nitric oxide donor isosorbide mononitrate reduces cesarean delivery rates in nulliparous women with an unfavorable cervix...
  24. pmc Effect of routine controlled cord traction as part of the active management of the third stage of labour on postpartum haemorrhage: multicentre randomised controlled trial (TRACOR)
    Catherine Deneux-Tharaux
    INSERM U953, Epidemiologic Research in Perinatal, Women s, and Children s Health, Pierre et Marie Curie University, Paris, France
    BMJ 346:f1541. 2013
    ..To assess the impact of controlled cord traction on the incidence of postpartum haemorrhage and other characteristics of the third stage of labour in a high resource setting...
  25. ncbi [Pre-existing diabetes and pregnancy]
    Jacques Lepercq
    Maternite Port Royal, Hopital Cochin, AP HP, Universite Paris Descartes, 75014 Paris, France
    Rev Prat 62:917-20. 2012
    ..The improved prognosis of pregnancies in women with pre-existing diabetes relies on preconception programming (therefore an effective contraception), multidisciplinary collaboration and appropriate management of these pregnancies...
  26. ncbi [Leptin in pregnancy: facts, questions and future]
    J Lepercq
    Service de Gynecologie Obstetrique, Groupe Hospitalier Cochin Saint Vincent de Paul APHP, 82, avenue Denfert Rochereau, 75674 Paris Cedex 14, France
    Gynecol Obstet Fertil 35:89-95. 2007
    ..Furthermore, umbilical leptin can be viewed as a biomarker of fetal adiposity. Our aim is to review the putative roles of leptin in pregnancy...
  27. pmc Low rate of pandemic A/H1N1 2009 influenza infection and lack of severe complication of vaccination in pregnant women: a prospective cohort study
    Odile Launay
    Universite Paris Descartes, Paris, France
    PLoS ONE 7:e52303. 2012
    ..The objectives of the COFLUPREG study, initially set up to assess the incidence of serious forms of A/H1N1 influenza, were to assess the consequences of maternal vaccination on pregnancy outcomes and maternal seroprotection at delivery...
  28. ncbi [Principal complications of pregnancy. Part one: gestational diabetes]
    Jacques Lepercq
    Service de Gynecologie Obstetrique, Hopital Cochin Saint Vincent de Paul, 75674 Paris Cedex 14
    Rev Prat 56:891-4. 2006
  29. ncbi [Gestational diabetes mellitus]
    Jacques Lepercq
    Universite Paris 5, Service de Gynecologie Obstetrique, Groupe Hospitalier Cochin Saint Vincent De Paul, AP HP, 75014 Paris
    Rev Prat 60:514-6. 2010
    ..Obese and overweight women have increased risks of perinatal complications...
  30. ncbi Intravenous fetal exchange transfusion before 22 weeks of gestation in early and severe red-cell fetomaternal alloimmunization
    Marie Helene Poissonnier
    Service de Gynecologie Obstetrique, Hopital Cochin Saint Vincent de Paul, Universite Paris V, Paris, France
    Fetal Diagn Ther 18:467-71. 2003
    ..To determine the perinatal outcome in severe red-cell fetomaternal alloimmunization...
  31. pmc Evaluation of cefotaxime and desacetylcefotaxime concentrations in cord blood after intrapartum prophylaxis with cefotaxime
    Jacques Lepercq
    Universite Paris Descartes, and Service de Gynécologie Obstétrique, Groupe Hospitalier Cochin Saint Vincent De Paul, 82, avenue Denfert Rochereau, Paris 75014, FranceParis, France
    Antimicrob Agents Chemother 53:2342-5. 2009
    ..The effectiveness of this regimen for the prevention of neonatal sepsis needs to be evaluated with a larger population...
  32. doi Factor H, membrane cofactor protein, and factor I mutations in patients with hemolysis, elevated liver enzymes, and low platelet count syndrome
    Fadi Fakhouri
    Department of Nephrology, Assistance Publique Hopitaux de Paris, Hopital Necker, Universite Paris Descartes, INSERM U845, Paris, France
    Blood 112:4542-5. 2008
    ..Our results suggest that an abnormal control of the complement alternative pathway is a risk factor for the occurrence of HELLP syndrome...
  33. ncbi Identification of distinct quantitative trait Loci affecting length or weight variability at birth in humans
    Delphine Fradin
    Institut National de la Santé et de la Recherche Médicale U561, Hopital Saint Vincent de Paul, 82 avenue Denfert Rochereau, 75014 Paris, France
    J Clin Endocrinol Metab 91:4164-70. 2006
    ..The variability of human fetal growth is multifactorial. Twin and family studies demonstrate that genetic determinants influence normal fetal growth, but the responsible genetic polymorphisms are unknown...
  34. ncbi 'Non-Mendelian' genetics of fetal growth
    D Fradin
    Department of Pediatric Endocrinology and INSERM U561, Hopital Saint Vincent de Paul, Paris, France
    J Endocrinol Invest 29:11-5. 2006
    ....
  35. ncbi Venous thromboembolism during pregnancy: a retrospective study of enoxaparin safety in 624 pregnancies
    J Lepercq
    , , Paris, France
    BJOG 108:1134-40. 2001
    ..3%) were reported. CONCLUSIONS: The incidence of adverse events reported could be explained by the high risk profile of the study population. Overall, this retrospective study suggests enoxaparin is well tolerated during pregnancy...
  36. ncbi TNF-alpha is a predictor of insulin resistance in human pregnancy
    John P Kirwan
    Department of Reproductive Biology, Case Western Reserve University School of Medicine at MetroHealth Medical Center, Bell Greve Building Rm G 232E, 2500 MetroHealth Drive, Cleveland, OH 44109 1998, USA
    Diabetes 51:2207-13. 2002
    ....
  37. ncbi The known and unknown of leptin in pregnancy
    Sylvie Hauguel-De Mouzon
    Case Western Reserve University, MetroHealth Medical Center, Cleveland, OH 44109, USA
    Am J Obstet Gynecol 194:1537-45. 2006
    ..We aim to demonstrate that studies of leptin in pregnancy largely have contributed to insight into the mechanisms of leptin action, both as a hormone and as a cytokine...
  38. ncbi French multicentric survey of outcome of pregnancy in women with pregestational diabetes
    Pierre Boulot
    Diabetes Care 26:2990-3. 2003
    ..To evaluate perinatal outcome in pregnancies in women with type 1 and type 2 diabetes and the influence of preconception care 10 years after the St. Vincent's declaration...