Romain Koszul

Summary

Country: France

Publications

  1. ncbi The complete mitochondrial genome sequence of the pathogenic yeast Candida (Torulopsis) glabrata
    Romain Koszul
    Unité de Génétique Moléculaire des Levures URA 2171 du CNRS, UFR 927 Université Pierre et Marie Curie, Institut Pasteur, 25 rue du Docteur Roux, 75724 Cedex 15, Paris, France
    FEBS Lett 534:39-48. 2003
  2. ncbi Genome evolution in yeasts
    Bernard Dujon
    Unité de Génétique Moléculaire des Levures, URA 2171 CNRS and UFR 927 Université Pierre et Marie Curie
    Nature 430:35-44. 2004
  3. pmc Segmental duplications arise from Pol32-dependent repair of broken forks through two alternative replication-based mechanisms
    Celia Payen
    Institut Pasteur, Unité de Génétique Moléculaire des Levures, CNRS, URA2171, Universite Pierre et Marie Curie Paris 6, UFR927, Paris, France
    PLoS Genet 4:e1000175. 2008
  4. pmc Csm4, in collaboration with Ndj1, mediates telomere-led chromosome dynamics and recombination during yeast meiosis
    Jennifer J Wanat
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, USA
    PLoS Genet 4:e1000188. 2008
  5. pmc Stability of large segmental duplications in the yeast genome
    Romain Koszul
    Unité de Génétique Moléculaire des Levures CNRS URA2171, UFR927 Université Pierre et Marie Curie, Département de Structure et Dynamique des Génomes, Institut Pasteur, Paris, 75724 Cedex 15, France
    Genetics 172:2211-22. 2006
  6. pmc Genome-wide replication landscape of Candida glabrata
    Stéphane Descorps-Declère
    Institut Pasteur, Center of Bioinformatics, Biostatistics and Integrative Biology C3BI, F 75015, Paris, France
    BMC Biol 13:69. 2015
  7. doi Filling annotation gaps in yeast genomes using genome-wide contact maps
    Hervé Marie-Nelly
    Institut Pasteur, Groupe Régulation Spatiale des Génomes, Department of Genomes and Genetics, CNRS, UMR 3525, Institut Pasteur, Unité Imagerie et Modélisation, Department of Cell Biology and Infection, CNRS, URA 2582, F 75015 Paris, France, Institute for Research on Cancer and Ageing of Nice IRCAN, CNRS UMR 7284 INSERM U108, Universite de Nice Sophia Antipolis, 06107 Nice, France, CNRS, UMR7238, Biologie Computationnelle et Quantitative and Sorbonne Universités, UPMC Univ Paris 06, UMR7238, Biologie Computationnelle et Quantitative, F 75005, Paris, FranceInstitut Pasteur, Groupe Régulation Spatiale des Génomes, Department of Genomes and Genetics, CNRS, UMR 3525, Institut Pasteur, Unité Imagerie et Modélisation, Department of Cell Biology and Infection, CNRS, URA 2582, F 75015 Paris, France, Institute for Research on Cancer and Ageing of Nice IRCAN, CNRS UMR 7284 INSERM U108, School of Nursing
    Bioinformatics 30:2105-13. 2014
  8. doi A predictive computational model of the dynamic 3D interphase yeast nucleus
    Hua Wong
    Institut Pasteur, Groupe Imagerie et Modélisation, 75015 Paris, France
    Curr Biol 22:1881-90. 2012
  9. pmc Spatial reorganization of telomeres in long-lived quiescent cells
    Micol Guidi
    Institut Curie, PSL Research University, Paris, F 75248, France
    Genome Biol 16:206. 2015
  10. doi Generation and Analysis of Chromosomal Contact Maps of Yeast Species
    Axel Cournac
    Institut Pasteur, Department Genomes and Genetics, Groupe Régulation Spatiale des Génomes, 75015, Paris, France
    Methods Mol Biol 1361:227-45. 2016

Collaborators

Detail Information

Publications19

  1. ncbi The complete mitochondrial genome sequence of the pathogenic yeast Candida (Torulopsis) glabrata
    Romain Koszul
    Unité de Génétique Moléculaire des Levures URA 2171 du CNRS, UFR 927 Université Pierre et Marie Curie, Institut Pasteur, 25 rue du Docteur Roux, 75724 Cedex 15, Paris, France
    FEBS Lett 534:39-48. 2003
    ..Three group I introns each with an intronic open reading frame are present in the COX1 gene. This sequence is available under accession number AJ511533...
  2. ncbi Genome evolution in yeasts
    Bernard Dujon
    Unité de Génétique Moléculaire des Levures, URA 2171 CNRS and UFR 927 Université Pierre et Marie Curie
    Nature 430:35-44. 2004
    ....
  3. pmc Segmental duplications arise from Pol32-dependent repair of broken forks through two alternative replication-based mechanisms
    Celia Payen
    Institut Pasteur, Unité de Génétique Moléculaire des Levures, CNRS, URA2171, Universite Pierre et Marie Curie Paris 6, UFR927, Paris, France
    PLoS Genet 4:e1000175. 2008
    ....
  4. pmc Csm4, in collaboration with Ndj1, mediates telomere-led chromosome dynamics and recombination during yeast meiosis
    Jennifer J Wanat
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, USA
    PLoS Genet 4:e1000188. 2008
    ....
  5. pmc Stability of large segmental duplications in the yeast genome
    Romain Koszul
    Unité de Génétique Moléculaire des Levures CNRS URA2171, UFR927 Université Pierre et Marie Curie, Département de Structure et Dynamique des Génomes, Institut Pasteur, Paris, 75724 Cedex 15, France
    Genetics 172:2211-22. 2006
    ....
  6. pmc Genome-wide replication landscape of Candida glabrata
    Stéphane Descorps-Declère
    Institut Pasteur, Center of Bioinformatics, Biostatistics and Integrative Biology C3BI, F 75015, Paris, France
    BMC Biol 13:69. 2015
    ..In order to determine the whole replication program of the C. glabrata genome and its general chromosomal organization, we used deep-sequencing and chromosome conformation capture experiments...
  7. doi Filling annotation gaps in yeast genomes using genome-wide contact maps
    Hervé Marie-Nelly
    Institut Pasteur, Groupe Régulation Spatiale des Génomes, Department of Genomes and Genetics, CNRS, UMR 3525, Institut Pasteur, Unité Imagerie et Modélisation, Department of Cell Biology and Infection, CNRS, URA 2582, F 75015 Paris, France, Institute for Research on Cancer and Ageing of Nice IRCAN, CNRS UMR 7284 INSERM U108, Universite de Nice Sophia Antipolis, 06107 Nice, France, CNRS, UMR7238, Biologie Computationnelle et Quantitative and Sorbonne Universités, UPMC Univ Paris 06, UMR7238, Biologie Computationnelle et Quantitative, F 75005, Paris, FranceInstitut Pasteur, Groupe Régulation Spatiale des Génomes, Department of Genomes and Genetics, CNRS, UMR 3525, Institut Pasteur, Unité Imagerie et Modélisation, Department of Cell Biology and Infection, CNRS, URA 2582, F 75015 Paris, France, Institute for Research on Cancer and Ageing of Nice IRCAN, CNRS UMR 7284 INSERM U108, School of Nursing
    Bioinformatics 30:2105-13. 2014
    ....
  8. doi A predictive computational model of the dynamic 3D interphase yeast nucleus
    Hua Wong
    Institut Pasteur, Groupe Imagerie et Modélisation, 75015 Paris, France
    Curr Biol 22:1881-90. 2012
    ..These positional preferences correlate with gene expression and DNA repair, recombination, and replication. Yet the principles that govern nuclear organization remain poorly understood and detailed predictive models are lacking...
  9. pmc Spatial reorganization of telomeres in long-lived quiescent cells
    Micol Guidi
    Institut Curie, PSL Research University, Paris, F 75248, France
    Genome Biol 16:206. 2015
    ..In these conditions, as in most eukaryotic cells, silent chromatin that is mainly found at the 32 telomeres accumulates at the nuclear envelope, forming three to five foci...
  10. doi Generation and Analysis of Chromosomal Contact Maps of Yeast Species
    Axel Cournac
    Institut Pasteur, Department Genomes and Genetics, Groupe Régulation Spatiale des Génomes, 75015, Paris, France
    Methods Mol Biol 1361:227-45. 2016
    ..e., pair-end sequences) are influenced by these parameters. Here, we describe a complete pipeline to generate 3C-seq libraries and compute chromosomal contact maps of yeast species...
  11. doi Condensin- and Replication-Mediated Bacterial Chromosome Folding and Origin Condensation Revealed by Hi-C and Super-resolution Imaging
    Martial Marbouty
    Institut Pasteur, Department of Genomes and Genetics, Group Spatial Regulation of Genomes, 75015 Paris, France CNRS, UMR 3525, 75015 Paris, France
    Mol Cell 59:588-602. 2015
    ..Our results suggest that the precise 3D folding pattern of the origin domain plays a role in the regulation of replication initiation, chromosome organization, and DNA segregation. ..
  12. pmc Metagenomic chromosome conformation capture (meta3C) unveils the diversity of chromosome organization in microorganisms
    Martial Marbouty
    Groupe Régulation Spatiale des Génomes, Département Génomes et Génétique, Institut Pasteur, Paris, France
    elife 3:e03318. 2014
    ..Overall, this first meta3C study highlights the remarkable diversity of microorganisms chromosome organization, while providing an elegant and integrated approach to metagenomic analysis. ..
  13. pmc The centenary of Janssens's chiasmatype theory
    Romain Koszul
    Institut Pasteur, Group Spatial Regulation of Genomes, Department of Genomes and Genetics, F 75015 Paris, France
    Genetics 191:309-17. 2012
    ..This Perspectives aims to highlight the novelty of Janssens's chiasmatype theory by examining the historical background and our actual understanding of meiotic recombination...
  14. pmc Dynamic chromosome movements during meiosis: a way to eliminate unwanted connections?
    Romain Koszul
    CNRS URA2171, Institut Pasteur, Unité de Génétique Moléculaire des Levures, 25 rue du Dr Roux, 75015 Paris, France
    Trends Cell Biol 19:716-24. 2009
    ..Recent advances shed light on the contribution of protein complexes involved in the meiotic movements in chromosome dynamics during the mitotic program...
  15. pmc Filling the gap: Micro-C accesses the nucleosomal fiber at 100-1000 bp resolution
    Julien Mozziconacci
    Theoretical Physics for Condensed Matter Laboratory, UPMC, CNRS UMR 7600, Sorbonne Universités, place Jussieu, 75005, Paris, France
    Genome Biol 16:169. 2015
    ..These domains encompass one to five consecutive genes and are delimited by highly active promoters. ..
  16. doi Metagenome Analysis Exploiting High-Throughput Chromosome Conformation Capture (3C) Data
    Martial Marbouty
    Institut Pasteur, Department of Genomes and Genetics, Groupe Régulation Spatiale des Génomes, 75015 Paris, France CNRS, UMR 3525, 75015 Paris, France
    Trends Genet 31:673-82. 2015
    ..It also has the potential to assign correctly extra-chromosomal elements, such as plasmids, mobile elements and phages, to their host cells. ..
  17. doi Purification of G1 daughter cells from different Saccharomycetes species through an optimized centrifugal elutriation procedure
    Martial Marbouty
    Institut Pasteur, Group Spatial Regulation of Genomes, Department of Genomes and Genetics, F 75015, Paris, France CNRS, UMR3525, F 75015, Paris, France
    Yeast 31:159-66. 2014
    ..cerevisiae, Candida glabrata, Lachancea kluyveri and Pichia sorbitophila) and could theoretically be applied to any culture of single, individual cells...
  18. pmc Eucaryotic genome evolution through the spontaneous duplication of large chromosomal segments
    Romain Koszul
    Unité de Génétique Moléculaire des Levures, Département de Structure et Dynamique des Génomes, Institut Pasteur, Paris, France
    EMBO J 23:234-43. 2004
    ..Aneuploidization events or suppressor mutations that do not involve large-scale rearrangements accounted for the rest of the reversion events (in 26 and 16% of the strains, respectively)...
  19. pmc Large-scale exploration of growth inhibition caused by overexpression of genomic fragments in Saccharomyces cerevisiae
    Jeanne Boyer
    Unité de Génétique Moléculaire des Levures, URA2171 CNRS and UFR 927 Université Pierre et Marie Curie, Paris Cedex 15, France
    Genome Biol 5:R72. 2004
    ....