Didier Guillemot

Summary

Affiliation: Institut Pasteur
Country: France

Publications

  1. pmc Significant reduction of antibiotic use in the community after a nationwide campaign in France, 2002-2007
    Elifsu Sabuncu
    INSERM, U657, Paris, France
    PLoS Med 6:e1000084. 2009
  2. pmc Comparing human papillomavirus prevalences in women with normal cytology or invasive cervical cancer to rank genotypes according to their oncogenic potential: a meta-analysis of observational studies
    Erik Bernard
    Institut Pasteur, Unité de Pharmaco Épidémiologie et Maladies Infectieuses, 25 28 Rue du Dr Roux, 75724 Paris Cedex 15 France
    BMC Infect Dis 13:373. 2013
  3. pmc Benchmarking clinical management of spinal and non-spinal disorders using quality of life: results from the EPI3-LASER survey in primary care
    Michel Rossignol
    Department of Epidemiology, Biostatistics and Occupational Health, McGill University, 4820 Boulevard Saint Laurent, Montreal, QC H2T 1R5, Canada
    Eur Spine J 20:2210-6. 2011
  4. pmc Who seeks primary care for musculoskeletal disorders (MSDs) with physicians prescribing homeopathic and other complementary medicine? Results from the EPI3-LASER survey in France
    Michel Rossignol
    Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Canada and LA SER Centre for Risk Research, Montreal, Canada
    BMC Musculoskelet Disord 12:21. 2011
  5. pmc Antibiotic innovation may contribute to slowing the dissemination of multiresistant Streptococcus pneumoniae: the example of ketolides
    Lulla Opatowski
    Unité de Pharmacoépidémiologie et Maladies Infectieuses, Institut Pasteur, Paris, France
    PLoS ONE 3:e2089. 2008
  6. pmc Antibiotic dose impact on resistance selection in the community: a mathematical model of beta-lactams and Streptococcus pneumoniae dynamics
    Lulla Opatowski
    Institut Pasteur, Unité de Pharmacoépidémiologie et Maladies Infectieuses, Paris, France
    Antimicrob Agents Chemother 54:2330-7. 2010
  7. pmc Intrinsic epidemicity of Streptococcus pneumoniae depends on strain serotype and antibiotic susceptibility pattern
    Matthieu Domenech de Cellès
    Unité de Pharmacoépidémiologie et Maladies Infectieuses, Institut Pasteur, Paris, France
    Antimicrob Agents Chemother 55:5255-61. 2011
  8. pmc Antibiotic reduction campaigns do not necessarily decrease bacterial resistance: the example of methicillin-resistant Staphylococcus aureus
    Lidia Kardas-Sloma
    Laboratoire Modélisation et Surveillance des Risques pour la Sécurité Sanitaire, Conservatoire National des Arts et Metiers, Paris, France
    Antimicrob Agents Chemother 57:4410-6. 2013
  9. pmc Impact of capsular switch on invasive pneumococcal disease incidence in a vaccinated population
    Laura Temime
    CNAM, Paris, France
    PLoS ONE 3:e3244. 2008
  10. pmc S. pneumoniae transmission according to inclusion in conjugate vaccines: Bayesian analysis of a longitudinal follow-up in schools
    Simon Cauchemez
    INSERM U707, Paris, France
    BMC Infect Dis 6:14. 2006

Collaborators

Detail Information

Publications29

  1. pmc Significant reduction of antibiotic use in the community after a nationwide campaign in France, 2002-2007
    Elifsu Sabuncu
    INSERM, U657, Paris, France
    PLoS Med 6:e1000084. 2009
    ..We report the evaluation of this campaign by analyzing the evolution of outpatient antibiotic use in France 2000-2007, according to therapeutic class and geographic and age-group patterns...
  2. pmc Comparing human papillomavirus prevalences in women with normal cytology or invasive cervical cancer to rank genotypes according to their oncogenic potential: a meta-analysis of observational studies
    Erik Bernard
    Institut Pasteur, Unité de Pharmaco Épidémiologie et Maladies Infectieuses, 25 28 Rue du Dr Roux, 75724 Paris Cedex 15 France
    BMC Infect Dis 13:373. 2013
    ..Therefore, it appears essential to rank HPV genotypes according to their oncogenic potential for invasive cervical cancer, independently of their respective prevalences...
  3. pmc Benchmarking clinical management of spinal and non-spinal disorders using quality of life: results from the EPI3-LASER survey in primary care
    Michel Rossignol
    Department of Epidemiology, Biostatistics and Occupational Health, McGill University, 4820 Boulevard Saint Laurent, Montreal, QC H2T 1R5, Canada
    Eur Spine J 20:2210-6. 2011
    ..001). In conclusion, anxiety and depressive disorders were commonly reported by GPs among chronic MSD patients. Their prescriptions of psychotropic and analgesic drugs were consistent with patients' self-rated mental and physical health...
  4. pmc Who seeks primary care for musculoskeletal disorders (MSDs) with physicians prescribing homeopathic and other complementary medicine? Results from the EPI3-LASER survey in France
    Michel Rossignol
    Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Canada and LA SER Centre for Risk Research, Montreal, Canada
    BMC Musculoskelet Disord 12:21. 2011
    ....
  5. pmc Antibiotic innovation may contribute to slowing the dissemination of multiresistant Streptococcus pneumoniae: the example of ketolides
    Lulla Opatowski
    Unité de Pharmacoépidémiologie et Maladies Infectieuses, Institut Pasteur, Paris, France
    PLoS ONE 3:e2089. 2008
    ..The aims of this study were to assess the potential dissemination of newly emerged resistances and to control the selection of strains already multiresistant to existing antimicrobials...
  6. pmc Antibiotic dose impact on resistance selection in the community: a mathematical model of beta-lactams and Streptococcus pneumoniae dynamics
    Lulla Opatowski
    Institut Pasteur, Unité de Pharmacoépidémiologie et Maladies Infectieuses, Paris, France
    Antimicrob Agents Chemother 54:2330-7. 2010
    ..Surveillance networks are therefore encouraged to collect both daily antibiotic exposure frequencies and individual prescribed doses...
  7. pmc Intrinsic epidemicity of Streptococcus pneumoniae depends on strain serotype and antibiotic susceptibility pattern
    Matthieu Domenech de Cellès
    Unité de Pharmacoépidémiologie et Maladies Infectieuses, Institut Pasteur, Paris, France
    Antimicrob Agents Chemother 55:5255-61. 2011
    ..Further quantification of strain-specific epidemic potential is needed, especially in a context of extensive use of conjugate vaccines with the aim of preventing pneumococcal infections...
  8. pmc Antibiotic reduction campaigns do not necessarily decrease bacterial resistance: the example of methicillin-resistant Staphylococcus aureus
    Lidia Kardas-Sloma
    Laboratoire Modélisation et Surveillance des Risques pour la Sécurité Sanitaire, Conservatoire National des Arts et Metiers, Paris, France
    Antimicrob Agents Chemother 57:4410-6. 2013
    ..It also highlights the fact that optimal gains will be obtained by coordinating interventions in hospitals and in the community, since the effect of an intervention in a given setting may be strongly affected by exogenous factors. ..
  9. pmc Impact of capsular switch on invasive pneumococcal disease incidence in a vaccinated population
    Laura Temime
    CNAM, Paris, France
    PLoS ONE 3:e3244. 2008
    ..In particular, pathogenic pneumococci may switch their capsular types and evade vaccine-conferred immunity...
  10. pmc S. pneumoniae transmission according to inclusion in conjugate vaccines: Bayesian analysis of a longitudinal follow-up in schools
    Simon Cauchemez
    INSERM U707, Paris, France
    BMC Infect Dis 6:14. 2006
    ..The eventual extent of this replacement is however unknown and depends on serotype-specific carriage and transmission characteristics...
  11. pmc Identifying more epidemic clones during a hospital outbreak of multidrug-resistant Acinetobacter baumannii
    Matthieu Domenech de Cellès
    Unité de Pharmacoépidémiologie et Maladies Infectieuses, Institut Pasteur, Paris, France
    PLoS ONE 7:e45758. 2012
    ..Building on these results, more epidemic clones could be identified, and could lead to follow-up studies dissecting the functional basis for variation in transmissibility of MDRAB lineages...
  12. doi request reprint Variability of intestinal colonization with third-generation cephalosporin-resistant Enterobacteriaceae and antibiotic use in intensive care units
    Anne C M Thiebaut
    INSERM, U657, Paris, France
    J Antimicrob Chemother 67:1525-36. 2012
    ..We assessed and compared β-lactam use, the prevalence of colonization with CRE at admission and the incidence of CRE acquisition across ICUs...
  13. doi request reprint Inhaled therapies, azithromycin and Mycobacterium abscessus in cystic fibrosis patients
    Emilie Catherinot
    Laboratoire de Microbiologie, Hôpital Raymond Poincaré et Hôpital Ambroise Paré, Assistance Publique Hopitaux de Paris, Paris, France
    Eur Respir J 41:1101-6. 2013
    ..In conclusion, there is no evidence for a link between M. abscessus complex lung disease and inhaled therapies or low-dose azithromycin in patients with CF...
  14. doi request reprint Emergence and dissemination of extended-spectrum beta-lactamase-producing Escherichia coli in the community: lessons from the study of a remote and controlled population
    Paul Louis Woerther
    Equipe d Accueil EA 3964 Université Paris Diderot and Centre National de Référence, Résistance bactérienne dans les flores commensales, Hopital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris AP HP, Paris, France
    J Infect Dis 202:515-23. 2010
    ..To overcome this problem, we studied a highly stable group of Amerindians for whom we reported an ESBL carriage prevalence of 3.2% in 2001...
  15. doi request reprint Antibiotics for nasopharyngitis are associated with a lower risk of office-based physician visit for acute otitis media within 14 days for 3- to 6-year-old children
    Jerome Salomon
    INSERM, U657, Paris, France
    J Eval Clin Pract 14:595-9. 2008
    ....
  16. pmc Outpatient antibiotic use in France between 2000 and 2010: after the nationwide campaign, it is time to focus on the elderly
    Adeline Bernier
    INSERM, U 657, Paris, France
    Antimicrob Agents Chemother 58:71-7. 2014
    ..9 to +29.6%) in 2009 (P < 0.0001). These results highlight the need for a better understanding of antibiotic use by the elderly, requiring research with targeted and tailored public health actions for this population. ..
  17. pmc Limits of patient isolation measures to control extended-spectrum beta-lactamase-producing Enterobacteriaceae: model-based analysis of clinical data in a pediatric ward
    Matthieu Domenech de Cellès
    Unité de Pharmacoépidémiologie et Maladies Infectieuses, Institut Pasteur, Paris, France
    BMC Infect Dis 13:187. 2013
    ..How to control the nosocomial ESBL-E transmission is a matter of debate. Contact isolation of patients has been recommended but evidence supporting it in non-outbreak settings has been inconclusive...
  18. pmc Prior caspofungin exposure in patients with hematological malignancies is a risk factor for subsequent fungemia due to decreased susceptibility in Candida spp.: a case-control study in Paris, France
    Elodie Blanchard
    INSERM U 657, Paris, France
    Antimicrob Agents Chemother 55:5358-61. 2011
    ..25; 95% confidence interval [95% CI], 1.68-16.35) and with an age of ≤ 65 years (OR = 3.27; 95% CI, 1.26-8.50)...
  19. pmc Impact of antibiotic exposure patterns on selection of community-associated methicillin-resistant Staphylococcus aureus in hospital settings
    Lidia Kardas-Sloma
    UPMC Universite Paris 06, F 75005, Paris, France
    Antimicrob Agents Chemother 55:4888-95. 2011
    ..This study demonstrates that antibiotic exposure strategies could participate in this control. This is all the more important in wards such as ICUs, which may play the role of incubators, promoting CA-MRSA selection in hospitals...
  20. doi request reprint Contribution of mathematical modeling to the fight against bacterial antibiotic resistance
    Lulla Opatowski
    Institut Pasteur, Unité de Pharmacoépidémiologie et Maladies Infectieuses, INSERM U 657, Paris, France
    Curr Opin Infect Dis 24:279-87. 2011
    ..Herein, we summarize the main published studies to illustrate the contribution of models for understanding both within-host and population-based phenomena. We then suggest possible topics for future studies...
  21. ncbi request reprint Reduction of antibiotic use in the community reduces the rate of colonization with penicillin G-nonsusceptible Streptococcus pneumoniae
    Didier Guillemot
    Centre de Resource en Biostatistiques, Epidémiologie et Pharmacoépidemiologie, Institut Pasteur, Unit 657, INSERM, France
    Clin Infect Dis 41:930-8. 2005
    ..This study evaluates the effect of community-based intervention strategies on the prevalence of pnsp colonization...
  22. doi request reprint Organic and conventional fruits and vegetables contain equivalent counts of Gram-negative bacteria expressing resistance to antibacterial agents
    Raymond Ruimy
    EA 6934 lt lt Résistance Bactérienne in vivo gt gt Université Paris Diderot, and Centre National de Référence sur la Résistance aux Antibiotiques, Hopital Bichat Claude Bernard, APHP, Paris, France
    Environ Microbiol 12:608-15. 2010
    ..which grouped into two phylotypes and all carrying the bla(RAHN) gene. Thus, both organic and conventional fruits and vegetables may constitute significant sources of resistant bacteria and of resistance genes...
  23. pmc Insights into persistence mechanisms of a zoonotic virus in bat colonies using a multispecies metapopulation model
    Margarita Pons-Salort
    Institut Pasteur, Unité de Pharmaco Épidémiologie et Maladies Infectieuses, Paris, France INSERM, U657, Paris, France Univ Versailles Saint Quentin en Yvelines, EA 4499, Faculte de Medecine Paris Ile de France Ouest, Garches, France
    PLoS ONE 9:e95610. 2014
    ..schreibersii's incubation- and immune-period durations, but not the infectious period length, were the most relevant factors driving virus persistence. ..
  24. pmc Imported episodic rabies increases patient demand for and physician delivery of antirabies prophylaxis
    Zélie Lardon
    INSERM, U657 and Institut Pasteur, PhEMI, Paris, France
    PLoS Negl Trop Dis 4:e723. 2010
    ....
  25. doi request reprint Vaccines: specific features, simulation of impact and medico-economic modelling
    Odile Launay
    Universite Paris Descartes, AP HP, INSERM, CIC de vaccinologie Cochin Pasteur, Paris, France
    Therapie 65:357-65, 347-55. 2010
    ..The Round Table has also proposed the creation of a working group to be responsible for pursuing, monitoring and implementing the proposals formulated...
  26. ncbi request reprint Effect of mutator P. aeruginosa on antibiotic resistance acquisition and respiratory function in cystic fibrosis
    Agnes Ferroni
    Laboratoire de Microbiologie, Assistance Publique Hopitaux de Paris, Hopital Necker Enfants Malades, Paris, France
    Pediatr Pulmonol 44:820-5. 2009
    ..We determined the relationship between the presence of P. aeruginosa mutator strains and cystic fibrosis clinical characteristics...
  27. pmc Did media attention of the 2009 A(H1N1) influenza epidemic increase outpatient antibiotic use in France?: A time-series analysis
    Adeline Bernier
    INSERM, U 657, Paris, France
    PLoS ONE 8:e69075. 2013
    ..We first determined the period when media coverage was high, and then compared, during this period, observed outpatient antibiotic consumption to estimated outpatient antibiotic consumption "without media attention"...
  28. ncbi request reprint Antibodies to tetanus, diphtheria and pertussis among healthy adults vaccinated according to the French vaccination recommendations
    Odile Launay
    Faculte de Medecine, Universite Paris Descartes, Paris, France
    Hum Vaccin 5:341-6. 2009
    ..They also indicate the need for better implementation of the current recommendations for pertussis-vaccine boosters in adults...
  29. pmc Major role for amphotericin B-flucytosine combination in severe cryptococcosis
    Francoise Dromer
    Institut Pasteur, Mycologie Moléculaire, Centre National de Référence Mycologie et Antifongiques, CNRS URA3012, Paris, France
    PLoS ONE 3:e2870. 2008
    ..We assessed here the optimal therapeutic strategies for severe cryptococcosis using the observational prospective CryptoA/D study after analyzing routine clinical care of cryptococcosis in university or tertiary care hospitals...