L Frangeul

Summary

Affiliation: Institut Pasteur
Country: France

Publications

  1. pmc Growth of Yersinia pseudotuberculosis in human plasma: impacts on virulence and metabolic gene expression
    Marie Laure Rosso
    Inserm U801, Lille, F 59019, université Lille II, faculté de médecine Henri Warembourg, Lille, France
    BMC Microbiol 8:211. 2008
  2. pmc Genome-wide computational prediction of tandem gene arrays: application in yeasts
    Laurence Despons
    Universite de Strasbourg, CNRS UMR7156, Strasbourg, France
    BMC Genomics 11:56. 2010
  3. ncbi request reprint Pattern of HCV antibodies with special reference to NS5A reactivity in HCV-infected patients: relation to viral genotype, cryoglobulinemia and response to interferon
    L Frangeul
    Service de Virologie, CHU Pitie Salpetriere, Paris, France
    J Hepatol 28:538-43. 1998
  4. ncbi request reprint Mutations in NS5A region of hepatitis C virus genome correlate with presence of NS5A antibodies and response to interferon therapy for most common European hepatitis C virus genotypes
    L Frangeul
    Service de Virologie, Centre Hospitalo Universitaire Pitie Salpetriere, Paris, France
    Hepatology 28:1674-9. 1998
  5. pmc Highly plastic genome of Microcystis aeruginosa PCC 7806, a ubiquitous toxic freshwater cyanobacterium
    Lionel Frangeul
    Institut Pasteur, Pasteur Genopole, F 75015, Paris, France
    BMC Genomics 9:274. 2008
  6. ncbi request reprint CAAT-Box, Contigs-Assembly and Annotation Tool-Box for genome sequencing projects
    L Frangeul
    Genopole, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris 15, France
    Bioinformatics 20:790-7. 2004
  7. ncbi request reprint Comparative genomics of Listeria species
    P Glaser
    , , Service d'Informatique Scientifique, Institut Pasteur, 25-28 rue du Dr. Roux, 75724 Paris, France
    Science 294:849-52. 2001
  8. ncbi request reprint Liver/kidney microsome antibody type 1 and hepatitis C virus infection
    F Lunel
    Service de Bactério virologie, Hopital Pitie Salpetriere, Paris, France
    Hepatology 16:630-6. 1992
  9. pmc The 102-kilobase pgm locus of Yersinia pestis: sequence analysis and comparison of selected regions among different Yersinia pestis and Yersinia pseudotuberculosis strains
    C Buchrieser
    Laboratoire de Génomique des Microorganismes Pathogènes, Institut Pasteur, 75724 Paris Cedex 15, France
    Infect Immun 67:4851-61. 1999
  10. ncbi request reprint Transcriptome analysis of Listeria monocytogenes identifies three groups of genes differently regulated by PrfA
    Eliane Milohanic
    Unité des Interactions Bactéries Cellules and Laboratoire de Génomique des Microorganismes Pathogènes, Institut Pasteur, 28, rue du Docteur Roux, 75724 Paris Cedex 15, France
    Mol Microbiol 47:1613-25. 2003

Detail Information

Publications29

  1. pmc Growth of Yersinia pseudotuberculosis in human plasma: impacts on virulence and metabolic gene expression
    Marie Laure Rosso
    Inserm U801, Lille, F 59019, université Lille II, faculté de médecine Henri Warembourg, Lille, France
    BMC Microbiol 8:211. 2008
    ..However, in immunocompromised patients, the microorganism may disseminate from the digestive tract and thus cause a systemic infection with septicemia...
  2. pmc Genome-wide computational prediction of tandem gene arrays: application in yeasts
    Laurence Despons
    Universite de Strasbourg, CNRS UMR7156, Strasbourg, France
    BMC Genomics 11:56. 2010
    ..The originality of this method lies in the search of protein sequence similarities in the vicinity of each coding sequence, which allows the prediction of tandem duplicated gene copies independently of their functionality...
  3. ncbi request reprint Pattern of HCV antibodies with special reference to NS5A reactivity in HCV-infected patients: relation to viral genotype, cryoglobulinemia and response to interferon
    L Frangeul
    Service de Virologie, CHU Pitie Salpetriere, Paris, France
    J Hepatol 28:538-43. 1998
    ..0 Ortho Diagnostic and INNO-LIA HCV Ab III Innogenetics) among patients infected with different hepatitis C virus genotypes, with or without cryoglobulinemia, and in patients treated with interferon...
  4. ncbi request reprint Mutations in NS5A region of hepatitis C virus genome correlate with presence of NS5A antibodies and response to interferon therapy for most common European hepatitis C virus genotypes
    L Frangeul
    Service de Virologie, Centre Hospitalo Universitaire Pitie Salpetriere, Paris, France
    Hepatology 28:1674-9. 1998
    ..For genotype 3, a potential ISD mutation could be located at the codon 2161...
  5. pmc Highly plastic genome of Microcystis aeruginosa PCC 7806, a ubiquitous toxic freshwater cyanobacterium
    Lionel Frangeul
    Institut Pasteur, Pasteur Genopole, F 75015, Paris, France
    BMC Genomics 9:274. 2008
    ..Microcystis blooms are often toxic, potentially fatal to animals and humans, and may cause environmental problems. There has been little investigation of the genomics of these cyanobacteria...
  6. ncbi request reprint CAAT-Box, Contigs-Assembly and Annotation Tool-Box for genome sequencing projects
    L Frangeul
    Genopole, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris 15, France
    Bioinformatics 20:790-7. 2004
    ..Using this strategy, the user works with a group of IPFs independently of the closure phase progression. The IPFs are accessible by a web server and can therefore be modified and commented by different groups...
  7. ncbi request reprint Comparative genomics of Listeria species
    P Glaser
    , , Service d'Informatique Scientifique, Institut Pasteur, 25-28 rue du Dr. Roux, 75724 Paris, France
    Science 294:849-52. 2001
    ..The presence of 270 L. monocytogenes and 149 L. innocua strain-specific genes (clustered in 100 and 63 islets, respectively) suggests that virulence in Listeria results from multiple gene acquisition and deletion events...
  8. ncbi request reprint Liver/kidney microsome antibody type 1 and hepatitis C virus infection
    F Lunel
    Service de Bactério virologie, Hopital Pitie Salpetriere, Paris, France
    Hepatology 16:630-6. 1992
    ..only 17% of the recombinant immunoblot assay-positive patients).(ABSTRACT TRUNCATED AT 250 WORDS)..
  9. pmc The 102-kilobase pgm locus of Yersinia pestis: sequence analysis and comparison of selected regions among different Yersinia pestis and Yersinia pseudotuberculosis strains
    C Buchrieser
    Laboratoire de Génomique des Microorganismes Pathogènes, Institut Pasteur, 75724 Paris Cedex 15, France
    Infect Immun 67:4851-61. 1999
    ..Furthermore, sequence comparisons among 29 Yersinia strains suggest that Y. pestis is a recently emerged pathogen that is probably entering the initial phase of reductive evolution...
  10. ncbi request reprint Transcriptome analysis of Listeria monocytogenes identifies three groups of genes differently regulated by PrfA
    Eliane Milohanic
    Unité des Interactions Bactéries Cellules and Laboratoire de Génomique des Microorganismes Pathogènes, Institut Pasteur, 28, rue du Docteur Roux, 75724 Paris Cedex 15, France
    Mol Microbiol 47:1613-25. 2003
    ..This study reveals that PrfA can act as an activator or a repressor and suggests that PrfA may directly or indirectly activate different sets of genes in association with different sigma factors...
  11. ncbi request reprint The complete mitochondrial genome sequence of the pathogenic yeast Candida (Torulopsis) glabrata
    Romain Koszul
    Unité de Génétique Moléculaire des Levures URA 2171 du CNRS, UFR 927 Université Pierre et Marie Curie, Institut Pasteur, 25 rue du Docteur Roux, 75724 Cedex 15, Paris, France
    FEBS Lett 534:39-48. 2003
    ..Three group I introns each with an intronic open reading frame are present in the COX1 gene. This sequence is available under accession number AJ511533...
  12. ncbi request reprint Transcriptome analysis of Yersinia pestis in human plasma: an approach for discovering bacterial genes involved in septicaemic plague
    Sylvie Chauvaux
    Yersinia Research Unit, Institut Pasteur, 28 rue du Dr Roux, F 75724 Paris Cedex 15, France
    Microbiology 153:3112-24. 2007
    ..Eleven of these genes were specifically transcribed at 37 degrees C and may thus represent new virulence factors that are important during the septicaemic phase of human plague...
  13. pmc Pleiotropic role of quorum-sensing autoinducer 2 in Photorhabdus luminescens
    Evelyne Krin
    Unite de Genetique des Genomes Bacteriens URA2171, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Appl Environ Microbiol 72:6439-51. 2006
    ..Finally, we showed that the luxS-deficient strain had attenuated virulence against the lepidopteran Spodoptera littoralis. We concluded that AI-2 is involved mainly in early steps of insect invasion in P. luminescens...
  14. ncbi request reprint Genome evolution in yeasts
    Bernard Dujon
    Unité de Génétique Moléculaire des Levures, URA 2171 CNRS and UFR 927 Université Pierre et Marie Curie
    Nature 430:35-44. 2004
    ....
  15. ncbi request reprint The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens
    Eric Duchaud
    Laboratoire de Génomique des Microorganismes Pathogènes, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Nat Biotechnol 21:1307-13. 2003
    ..Moreover, newly identified insecticidal proteins may be effective alternatives for the control of insect pests...
  16. pmc DNA macroarray for identification and typing of Staphylococcus aureus isolates
    Salim Trad
    Département Ecosystèmes et Epidémiologie des Maladies Infectieuses, Institut Pasteur, Paris, France
    J Clin Microbiol 42:2054-64. 2004
    ..In conclusion, the macroarray designed for this study offers an attractive and rapid typing method which has the advantage of providing additional information concerning the gene content of the isolate of interest...
  17. pmc CandidaDB: a genome database for Candida albicans pathogenomics
    C d'Enfert
    Unité Postulante Biologie et Pathogénicité Fongiques, INRA USC 2019, Institut Pasteur, Paris, France
    Nucleic Acids Res 33:D353-7. 2005
    ..CandidaDB is accessible at http://genolist.pasteur.fr/CandidaDB...
  18. ncbi request reprint Lessons from a multicentre study of the detectability of viral genomes based on a two-round quality control of GB virus C (GBV-C)/hepatitis G virus (HGV) polymerase chain reaction assay
    J J Lefrere
    Unité de recherches biocliniques, Institut National de la Transfusion Sanguine, Paris, France
    J Virol Methods 85:117-24. 2000
    ....
  19. ncbi request reprint Genome sequence of Streptococcus agalactiae, a pathogen causing invasive neonatal disease
    Philippe Glaser
    Laboratoire de Génomique des Microorganismes Pathogènes, Institute Pasteur, Paris, France
    Mol Microbiol 45:1499-513. 2002
    ..Compared with other pathogenic streptococci, S. agalactiae shows the unique feature that pathogenicity islands may have an important role in virulence acquisition and in genetic diversity...
  20. ncbi request reprint Characterization of the flexible genome complement of the commensal Escherichia coli strain A0 34/86 (O83 : K24 : H31)
    Jana Hejnova
    Unité de Génomique des Microorganismes Pathogènes and CNRS URA 2171, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris, France
    Microbiology 151:385-98. 2005
    ..These results highlight the thin line between bacterial 'virulence' and 'fitness' or 'colonization' factors, and question the definition of enterobacterial virulence factors...
  21. pmc Genome microevolution of chikungunya viruses causing the Indian Ocean outbreak
    Isabelle Schuffenecker
    Centre National de Référence des Arbovirus, Institut Pasteur, Lyon, France
    PLoS Med 3:e263. 2006
    ..Besides the arthralgic form, 123 patients with a confirmed chikungunya infection have developed severe clinical signs, i.e., neurological signs or fulminant hepatitis...
  22. ncbi request reprint The complete mitochondrial genome of the yeast Kluyveromyces thermotolerans
    Emmanuel Talla
    Unité de Génétique Moléculaire des Levures URA 2171 CNRS, UFR 927 Université PM Curie, Institut Pasteur, 25 rue du Docteur Roux, F 75724 Paris Cedex 15, France
    FEBS Lett 579:30-40. 2005
    ..Interestingly, the predicted secondary structure of the abnormal tRNAThr1 contains 10 nucleotides in its anticodon loop. This sequence is available under EMBL Accession No. AJ634268...
  23. pmc New aspects regarding evolution and virulence of Listeria monocytogenes revealed by comparative genomics and DNA arrays
    Michel Doumith
    Laboratoire des Listeria, Centre National de Référence des Listeria, World Health Organization Collaborating Center for Foodborne Listeriosis, Institut Pasteur, 75724 Paris 15, France
    Infect Immun 72:1072-83. 2004
    ..monocytogenes strains...
  24. pmc Sequence of conjugative plasmid pIP1206 mediating resistance to aminoglycosides by 16S rRNA methylation and to hydrophilic fluoroquinolones by efflux
    Bruno Perichon
    Unite des Agents Antibacteriens, Institut Pasteur, Paris, France
    Antimicrob Agents Chemother 52:2581-92. 2008
    ....
  25. ncbi request reprint Surface proteins and the pathogenic potential of Listeria monocytogenes
    Didier Cabanes
    Unité des Interactions Bactéries Cellules, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Trends Microbiol 10:238-45. 2002
    ..We describe these families and discuss their putative implications for host-pathogen interactions...
  26. pmc Stress by heat shock induces massive down regulation of genes and allows differential allelic expression of the Gal/GalNAc lectin in Entamoeba histolytica
    Christian Weber
    Unité Biologie Cellulaire du Parasitisme, INSERM 786, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Eukaryot Cell 5:871-5. 2006
    ....
  27. pmc Complete nucleotide sequence of the LE1 prophage from the spirochete Leptospira biflexa and characterization of its replication and partition functions
    Pascale Bourhy
    Laboratoire des Spirochètes, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    J Bacteriol 187:3931-40. 2005
    ..These results enable the construction of new shuttle vectors for studying the genetics of Leptospira spp. This study will also contribute to a better knowledge of phages unrelated to lambdoid phages...
  28. ncbi request reprint Horizontal gene transfer of two cytoskeletal elements from a eukaryote to a cyanobacterium
    Arthur Guljamow
    Humboldt University, Institute of Biology, Department of Molecular Ecology, Chausseestr 117, 10115, Berlin, Germany
    Curr Biol 17:R757-9. 2007
  29. pmc A comparison of random sequence reads versus 16S rDNA sequences for estimating the biodiversity of a metagenomic library
    Chaysavanh Manichanh
    Digestive System Research Unit, University Hospital Vall d Hebron, CIBERehd, Bioinformatics and Genomics Program, Center for Genomic Regulation, Barcelona, Spain
    Nucleic Acids Res 36:5180-8. 2008
    ..RSRs can thus provide a good estimate of the biodiversity of a metagenomic library and, as an alternative to 16S, this approach is both faster and cheaper...