- A constraint-based model analysis of the metabolic consequences of increased NADPH oxidation in Saccharomyces cerevisiaeMagalie Celton
INRA, UMR1083, Sciences Pour l OEnologie, 2 place Viala, F 34060 Montpellier, France
Metab Eng 14:366-79. 2012..Our findings emphasize the robustness of yeast to alterations in NADPH metabolism and highlight the role of the glycerol-DHA cycle as a redox valve, providing additional NADPH from NADH under conditions of very high demand...
- Comparative analysis of missing value imputation methods to improve clustering and interpretation of microarray experimentsMagalie Celton
INSERM UMR S 726, Equipe de Bioinformatique Genomique et Moleculaire, DSIMB, Universite Paris Diderot Paris 7, 2 place Jussieu, Paris, France
BMC Genomics 11:15. 2010..In this study, we have evaluated twelve different usable methods, and their influence on the quality of gene clustering. Interestingly we have used several datasets, both kinetic and non kinetic experiments from yeast and human...
- A comparative transcriptomic, fluxomic and metabolomic analysis of the response of Saccharomyces cerevisiae to increases in NADPH oxidationMagalie Celton
INRA, UMR1083 SPO, Montpellier, France
BMC Genomics 13:317. 2012..Here, we studied the mechanisms underlying this metabolic response, through a combination of gene expression profiling and analyses of extracellular and intracellular metabolites and 13 C-flux analysis...