E Carniel

Summary

Affiliation: Institut Pasteur
Country: France

Publications

  1. pmc Characterization of a large chromosomal "high-pathogenicity island" in biotype 1B Yersinia enterocolitica
    E Carniel
    Unité de bactériologie moléculaire et médicale, Laboratoire des Yersinia, Institut Pasteur, Paris, France
    J Bacteriol 178:6743-51. 1996
  2. ncbi [The plague]
    Elisabeth Carniel
    Laboratoire des Yersinia, Institut Pasteur, 28, rue du Docteur Roux, 75724 Paris, France
    C R Biol 325:851-3; discussion 879-83. 2002
  3. doi Insights into the infective properties of YpfΦ, the Yersinia pestis filamentous phage
    Iman Chouikha
    Yersinia Research Unit, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Virology 407:43-52. 2010
  4. pmc Growth of Yersinia pseudotuberculosis in human plasma: impacts on virulence and metabolic gene expression
    Marie Laure Rosso
    Inserm U801, Lille, F 59019, université Lille II, faculté de médecine Henri Warembourg, Lille, France
    BMC Microbiol 8:211. 2008
  5. ncbi The Yersinia high-pathogenicity island: an iron-uptake island
    E Carniel
    Laboratoire des Yersinia, Unité des bactériologie moléculaire et médicale, Institut Pasteur, 28, rue du Dr Roux, 75724 Cedex 15, Paris, France
    Microbes Infect 3:561-9. 2001
  6. ncbi The Yersinia high-pathogenicity island
    E Carniel
    Laboratoire des Yersinia, Institut Pasteur, Paris, France
    Int Microbiol 2:161-7. 1999
  7. pmc The 102-kilobase pgm locus of Yersinia pestis: sequence analysis and comparison of selected regions among different Yersinia pestis and Yersinia pseudotuberculosis strains
    C Buchrieser
    Laboratoire de Génomique des Microorganismes Pathogènes, Institut Pasteur, 75724 Paris Cedex 15, France
    Infect Immun 67:4851-61. 1999
  8. pmc Characterization of chromosomal regions conserved in Yersinia pseudotuberculosis and lost by Yersinia pestis
    Flavie Pouillot
    Yersinia Research Unit, Institut Pasteur, Paris Cedex 15, France
    Infect Immun 76:4592-9. 2008
  9. ncbi A putative DNA adenine methyltransferase is involved in Yersinia pseudotuberculosis pathogenicity
    Flavie Pouillot
    Yersinia Research Unit, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Microbiology 153:2426-34. 2007
  10. doi Resistance to plague of Mus spretus SEG/Pas mice requires the combined action of at least four genetic factors
    L Chevallier
    Mouse Functional Genetics Unit, Institut Pasteur, Paris, France
    Genes Immun 14:35-41. 2013

Collaborators

Detail Information

Publications51

  1. pmc Characterization of a large chromosomal "high-pathogenicity island" in biotype 1B Yersinia enterocolitica
    E Carniel
    Unité de bactériologie moléculaire et médicale, Laboratoire des Yersinia, Institut Pasteur, Paris, France
    J Bacteriol 178:6743-51. 1996
    ..enterocolitica strains of biotype 1B indicates that most of the island is conserved, apart from 15 kb at the left-hand end which is variable, especially in the region where three repeated sequences are clustered...
  2. ncbi [The plague]
    Elisabeth Carniel
    Laboratoire des Yersinia, Institut Pasteur, 28, rue du Docteur Roux, 75724 Paris, France
    C R Biol 325:851-3; discussion 879-83. 2002
    ..No efficient and safe vaccines are currently available. The plague bacillus is one of the few organisms that could be used for biological warfare...
  3. doi Insights into the infective properties of YpfΦ, the Yersinia pestis filamentous phage
    Iman Chouikha
    Yersinia Research Unit, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Virology 407:43-52. 2010
    ..In contrast to other filamentous phages, the incoming YpfΦ genome inserts itself between two copies of the resident prophage. This analysis thus unravels infective properties specific to YpfΦ...
  4. pmc Growth of Yersinia pseudotuberculosis in human plasma: impacts on virulence and metabolic gene expression
    Marie Laure Rosso
    Inserm U801, Lille, F 59019, université Lille II, faculté de médecine Henri Warembourg, Lille, France
    BMC Microbiol 8:211. 2008
    ..However, in immunocompromised patients, the microorganism may disseminate from the digestive tract and thus cause a systemic infection with septicemia...
  5. ncbi The Yersinia high-pathogenicity island: an iron-uptake island
    E Carniel
    Laboratoire des Yersinia, Unité des bactériologie moléculaire et médicale, Institut Pasteur, 28, rue du Dr Roux, 75724 Cedex 15, Paris, France
    Microbes Infect 3:561-9. 2001
    ..Other types of iron-uptake systems are also carried by different pathogenicity islands in enterobacteria...
  6. ncbi The Yersinia high-pathogenicity island
    E Carniel
    Laboratoire des Yersinia, Institut Pasteur, Paris, France
    Int Microbiol 2:161-7. 1999
    ..A unique characteristic of the HPI is its wide distribution in various enterobacteria. Although first identified in Yersinia spp., it has subsequently been detected in other genera such as E. coli, Klebsiella and Citrobacter...
  7. pmc The 102-kilobase pgm locus of Yersinia pestis: sequence analysis and comparison of selected regions among different Yersinia pestis and Yersinia pseudotuberculosis strains
    C Buchrieser
    Laboratoire de Génomique des Microorganismes Pathogènes, Institut Pasteur, 75724 Paris Cedex 15, France
    Infect Immun 67:4851-61. 1999
    ..Furthermore, sequence comparisons among 29 Yersinia strains suggest that Y. pestis is a recently emerged pathogen that is probably entering the initial phase of reductive evolution...
  8. pmc Characterization of chromosomal regions conserved in Yersinia pseudotuberculosis and lost by Yersinia pestis
    Flavie Pouillot
    Yersinia Research Unit, Institut Pasteur, Paris Cedex 15, France
    Infect Immun 76:4592-9. 2008
    ..Therefore, despite their loss in Y. pestis, five of the nine Y. pseudotuberculosis-specific chromosomal loci studied play a role in the survival, growth, or virulence of this species...
  9. ncbi A putative DNA adenine methyltransferase is involved in Yersinia pseudotuberculosis pathogenicity
    Flavie Pouillot
    Yersinia Research Unit, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Microbiology 153:2426-34. 2007
    ..pestis by a horizontally acquired region which potentially encodes another methyltransferase. YamA might thus be dispensable for Y. pestis growth and virulence because this species has acquired another gene fulfilling the same functions...
  10. doi Resistance to plague of Mus spretus SEG/Pas mice requires the combined action of at least four genetic factors
    L Chevallier
    Mouse Functional Genetics Unit, Institut Pasteur, Paris, France
    Genes Immun 14:35-41. 2013
    ..Altogether, this study has clarified and enhanced our understanding of the genetic architecture of resistance to plague in SEG/Pas mice...
  11. ncbi 3 IS-RFLP: a powerful tool for geographical clustering of global isolates of Yersinia pestis
    A J L Leclercq
    Yersinia Research Unit, National Reference Laboratory and WHO Collaborative Center for Yersinia, Institut Pasteur, Paris, France
    Adv Exp Med Biol 603:322-6. 2007
    ..pestis isolates according to their geographical origin, and therefore that this method may be valuable for investigating the origin of new or re-emerging plague foci or for addressing forensic issues...
  12. pmc High-molecular-weight protein 2 of Yersinia enterocolitica is homologous to AngR of Vibrio anguillarum and belongs to a family of proteins involved in nonribosomal peptide synthesis
    I Guilvout
    Unité de bactériologie moléculaire et médicale, Institut Pasteur, Paris, France
    J Bacteriol 175:5488-504. 1993
    ..This finding suggests that HMWP2 may participate in the nonribosomal synthesis of small biologically active peptides...
  13. ncbi The high-pathogenicity island of Yersinia pseudotuberculosis can be inserted into any of the three chromosomal asn tRNA genes
    C Buchrieser
    Unité de bactériologie moléculaire et médicale, Laboratoire des Yersinia, Institut Pasteur, Paris, France
    Mol Microbiol 30:965-78. 1998
    ....
  14. ncbi Evaluation of O-antigen inactivation on Pla activity and virulence of Yersinia pseudotuberculosis harbouring the pPla plasmid
    Flavie Pouillot
    Yersinia Research Unit, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Microbiology 151:3759-68. 2005
    ..pseudotuberculosis a higher pathogenicity potential. These results also suggest that acquisition of pPla may not have been sufficient to confer an immediate higher pathogenic potential to the ancestor Y. pestis strain...
  15. pmc Oral vaccination against bubonic plague using a live avirulent Yersinia pseudotuberculosis strain
    Thierry Blisnick
    Yersinia Research Unit, Institut Pasteur, 28 rue du Dr Roux, Paris 75724, France
    Infect Immun 76:3808-16. 2008
    ..Our results thus validate the concept that an attenuated Y. pseudotuberculosis strain can be an efficient, inexpensive, safe, and easy-to-produce live vaccine for oral immunization against bubonic plague...
  16. ncbi The highly similar TMP kinases of Yersinia pestis and Escherichia coli differ markedly in their AZTMP phosphorylating activity
    V Chenal-Francisque
    Laboratoire des Yersinia, Institut Pasteur, Paris, France
    Eur J Biochem 265:112-9. 1999
    ..coli enzyme suggest that segments lying outside the main regions involved in nucleotide binding and catalysis are responsible for the different rates of AZTMP phosphorylation...
  17. ncbi A horizontally acquired filamentous phage contributes to the pathogenicity of the plague bacillus
    Anne Derbise
    Yersinia Research Unit, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Mol Microbiol 63:1145-57. 2007
    ..Continued maintenance of YpfPhi despite its high in vitro instability suggests that it confers selective advantages to Y. pestis under natural conditions...
  18. pmc Defective innate cell response and lymph node infiltration specify Yersinia pestis infection
    Françoise Guinet
    Unité des Yersinia, Institut Pasteur, Paris, France
    PLoS ONE 3:e1688. 2008
    ..These results shed light on pathophysiological processes that draw the line between a virulent and a hypervirulent pathogen...
  19. ncbi Transcriptome analysis of Yersinia pestis in human plasma: an approach for discovering bacterial genes involved in septicaemic plague
    Sylvie Chauvaux
    Yersinia Research Unit, Institut Pasteur, 28 rue du Dr Roux, F 75724 Paris Cedex 15, France
    Microbiology 153:3112-24. 2007
    ..Eleven of these genes were specifically transcribed at 37 degrees C and may thus represent new virulence factors that are important during the septicaemic phase of human plague...
  20. pmc Horizontal transfer of the high-pathogenicity island of Yersinia pseudotuberculosis
    Biliana Lesic
    Yersinia Research Unit, Institut Pasteur, 75724 Paris Cedex 15, France
    J Bacteriol 187:3352-8. 2005
    ..This lateral transfer also involved the HPI-adjacent sequences, leading to the mobilization of a chromosomal region at least 46 kb in size...
  21. pmc Resistance of Yersinia pestis to antimicrobial agents
    Marc Galimand
    Unite des Agents Antibacteriens, Institut Pasteur, Paris, France
    Antimicrob Agents Chemother 50:3233-6. 2006
  22. ncbi Fatal Yersinia enterocolitica biotype 4 serovar O:3 sepsis after red blood cell transfusion
    Alexandre Leclercq
    From the Pasteur Institute, National Reference Laboratory and WHO Collaborating Center for Yersinia, Paris, France
    Transfusion 45:814-8. 2005
    ..Although posttransfusion bacterial sepsis is rare, this complication is associated with a high mortality rate...
  23. ncbi Excision of the high-pathogenicity island of Yersinia pseudotuberculosis requires the combined actions of its cognate integrase and Hef, a new recombination directionality factor
    Biliana Lesic
    Yersinia Research Unit, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Mol Microbiol 52:1337-48. 2004
    ..The fact that the HPI, and probably several other pathogenicity islands, carry a machinery of integration/excision highly similar to those of bacteriophages argues for a phage-mediated acquisition and transfer of these elements...
  24. ncbi NKT cells-containing inflammatory lesions induced by Yersinia pseudotuberculosis glycolipids
    Françoise Guinet
    Unité de bactériologie moléculaire et médicale, Laboratoire et Centre de Référence des Yersinia, Institut Pasteur, 25 rue du Dr Roux, 75015 Paris, France
    Immunol Lett 80:113-8. 2002
    ..Moreover, the present findings show that invNKT cell response is not unique to mycobacterial glycolipids...
  25. pmc Delineation and analysis of chromosomal regions specifying Yersinia pestis
    Anne Derbise
    Institut Pasteur, Yersinia Research Unit, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Infect Immun 78:3930-41. 2010
    ..Therefore, our results suggest that acquisition of new chromosomal materials has not been of major importance in the dramatic change of life cycle that has accompanied the emergence of Y. pestis...
  26. pmc The Yersinia pestis chromosome encodes active addiction toxins
    Céline Goulard
    Yersinia Research Unit, Institut Pasteur, 28 rue du Dr Roux, F 75724 Paris Cedex 15, France
    J Bacteriol 192:3669-77. 2010
    ..pestis chromosome, at least 5 are functional in E. coli and/or in Y. pestis. This is the first demonstration of active addiction toxins produced by the plague agent...
  27. pmc Relationship between bacterial virulence and nucleotide metabolism: a mutation in the adenylate kinase gene renders Yersinia pestis avirulent
    Helene Munier-Lehmann
    Laboatoire de Chimie Structurale des Macromolécules, Institut Pasteur, Cedex 15, France
    Biochem J 373:515-22. 2003
    ..pestis killed 100% of the mice upon subcutaneous infection, whereas bacterial loads as high as 1.5 x 10(4) CFU of the adk mutant were unable to kill any animals...
  28. ncbi A rapid and simple method for inactivating chromosomal genes in Yersinia
    Anne Derbise
    Unité de bactériologie moléculaire et médicale, Laboratoire des Yersinia, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    FEMS Immunol Med Microbiol 38:113-6. 2003
    ..Using this method, three chromosomal loci were successfully disrupted in Yersinia pseudotuberculosis. The use of this technique allows rapid and efficient large-scale mutagenesis of Yersinia target chromosomal genes...
  29. pmc Transferable plasmid-mediated resistance to streptomycin in a clinical isolate of Yersinia pestis
    A Guiyoule
    Laboratoire des Yersinia, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris, France
    Emerg Infect Dis 7:43-8. 2001
    ..Emergence of resistance to streptomycin in Y. pestis represents a critical public health problem since this antibiotic is used as the first-line treatment against plague in many countries...
  30. ncbi Plasmids and pathogenicity islands of Yersinia
    E Carniel
    Laboratoire des Yersinia, Unité des bactériologie moléculaire et médicale, Institut Pasteur, 28, rue du Dr Roux, 75724 Paris, France
    Curr Top Microbiol Immunol 264:89-108. 2002
  31. ncbi A technique of intradermal injection of Yersinia to study Y. pestis physiopathology
    Françoise Guinet
    Laboratoire des Yersinia, Institut Pasteur, Paris, France
    Adv Exp Med Biol 529:73-8. 2003
  32. ncbi Evolution of pathogenic Yersinia, some lights in the dark
    Elisabeth Carniel
    Institut Pasteur, Laboratoire des Yersinia, 28 rue du Dr Roux, 75724 Paris, France
    Adv Exp Med Biol 529:3-12. 2003
  33. doi Mus spretus SEG/Pas mice resist virulent Yersinia pestis, under multigenic control
    C Blanchet
    Institut Pasteur, Mouse Functional Genetics Unit, Paris, France
    Genes Immun 12:23-30. 2011
    ..pestis challenge. The SEG strain therefore offers an invaluable opportunity to unravel mechanisms and underlying genetic factors of resistance against Y. pestis infection...
  34. pmc Characterization of atypical isolates of Yersinia intermedia and definition of two new biotypes
    Liliane Martin
    Institut Pasteur, Paris, France
    J Clin Microbiol 47:2377-80. 2009
    ..intermedia species. We thus propose that Brenner's biotyping scheme be updated by adding two new biotypes: 9 (for variant 1) and 10 (for variant 2) to the species Y. intermedia...
  35. pmc Evaluation of ribotyping as a tool for molecular typing of Yersinia pseudotuberculosis strains of worldwide origin
    Ekaterina Voskressenskaya
    Institut Pasteur, Yersinia Research Unit, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    J Clin Microbiol 43:6155-60. 2005
    ..pseudotuberculosis but that it has some limitations due to the small number of hybridizing bands that generate the diversity of the profiles...
  36. pmc Comparison of the effects of deferiprone versus deferoxamine on growth and virulence of Yersinia enterocolitica
    Biliana Lesic
    Laboratoire des Yersinia, Institut Pasteur, 75724 Paris Cedex 15, France
    Antimicrob Agents Chemother 46:1741-5. 2002
    ..enterocolitica septicemia in a mouse model of infection. Deferiprone may thus represent a useful alternative iron-chelation therapy during invasive Y. enterocolitica infections...
  37. pmc Efficient tracing of global isolates of Yersinia pestis by restriction fragment length polymorphism analysis using three insertion sequences as probes
    Gabriela Torrea
    Yersinia Research Unit, National Reference Laboratory and WHO Collaborating Center for Yersinia, Institut Pasteur, 75724 Paris Cedex 15, France
    J Clin Microbiol 44:2084-92. 2006
    ..Finally, this technique could be useful for the tracing of a Y. pestis isolate that has been used as a biological terrorism threat...
  38. pmc Palindromic unit-independent transposition of IS1397 in Yersinia pestis
    Caroline Wilde
    Unite de Programmation Moleculaire et Toxicologie Genetique, CNRS URA 1444, Laboratoire des Yersinia, Institut Pasteur, 25 rue du Dr Roux, 75724 Paris Cedex 15, France
    J Bacteriol 184:4739-46. 2002
    ..In this study, we show that for Yersinia pestis, a species deprived of PUs, IS1397 can transpose onto its chromosome, with transpositional hot spots. Our results are in favor of a direct recognition of target DNA by IS1397 transposase...
  39. pmc Plague: past, present, and future
    Nils Chr Stenseth
    Centre for Ecological and Evolutionary Synthesis, Department of Biology, University of Oslo, Oslo, Norway
    PLoS Med 5:e3. 2008
  40. ncbi High-frequency conjugative transfer of antibiotic resistance genes to Yersinia pestis in the flea midgut
    B Joseph Hinnebusch
    Laboratory of Human Bacterial Pathogenesis, National Institute of Allergy and Infectious Diseases, Hamilton, MT 59840, USA
    Mol Microbiol 46:349-54. 2002
    ..Horizontal gene transfer in the flea may be the source of antibiotic-resistant Y. pestis strains recently isolated from plague patients in Madagascar...
  41. ncbi Molecular epidemiological characterization of Yersinia pseudotuberculosis circulating in different geographic areas of the Russian Federation
    Ekaterina A Voskressenskaya
    St Petersburg Pasteur Institute
    Adv Exp Med Biol 529:391-4. 2003
  42. pmc Use of O-antigen gene cluster-specific PCRs for the identification and O-genotyping of Yersinia pseudotuberculosis and Yersinia pestis
    Tatiana Bogdanovich
    Department of Medical Biochemistry, University of Turku, Turku, Finland
    J Clin Microbiol 41:5103-12. 2003
    ..pseudotuberculosis isolates that had lost the expression of the O-antigen. The PCR-based O-genotyping can easily be applied in conventional laboratories, without the need for tedious preparation of a large set of specific antisera...
  43. pmc Microevolution and history of the plague bacillus, Yersinia pestis
    Mark Achtman
    Department of Molecular Biology, Max Planck Institut für Infektionsbiologie, D 10117 Berlin, Germany
    Proc Natl Acad Sci U S A 101:17837-42. 2004
    ..pestis inferred here is compatible with the dates of historical pandemic plague. However, it is premature to infer an association between any modern molecular grouping and a particular pandemic wave that occurred before the 20th century...
  44. pmc Sudden onset of pseudotuberculosis in humans, France, 2004-05
    Pascal Vincent
    Institut National de la Sante et de la Recherche Medicale INSERM, Lille, France
    Emerg Infect Dis 14:1119-22. 2008
    ..This increase represents transient amplification of a pathogen endemic to the area and may be related to increased prevalence of the pathogen in rodent reservoirs...
  45. ncbi Role of pathogenicity island-associated integrases in the genome plasticity of uropathogenic Escherichia coli strain 536
    Bianca Hochhut
    Institut für Molekulare Infektionsbiologie, Universitat Wurzburg, 97070 Wurzburg, Germany
    Mol Microbiol 61:584-95. 2006
    ..This work also demonstrates for the first time the existence of a cross-talk between integrases of different PAIs and shows that this cross-talk is unidirectional...
  46. doi Delineation of the recombination sites necessary for integration of pathogenicity islands II and III into the Escherichia coli 536 chromosome
    Caroline Wilde
    Universitat Wurzburg, Institut für Molekulare Infektionsbiologie, 97070 Wurzburg, Germany
    Mol Microbiol 68:139-51. 2008
    ..These data suggest that PAI intasomes differ from those of lambda and P4 integrase paradigms...
  47. pmc The complete genome sequence of Yersinia pseudotuberculosis IP31758, the causative agent of Far East scarlet-like fever
    Mark Eppinger
    J Craig Venter Institute The Institute for Genomic Research, Microbial Genomics, Rockville, Maryland, United States of America
    PLoS Genet 3:e142. 2007
    ....
  48. ncbi From the recent lessons of the Malagasy foci towards a global understanding of the factors involved in plague reemergence
    Jean Marc Duplantier
    Programme RAMSE, IRD Madagascar, Madagascar
    Vet Res 36:437-53. 2005
    ..pestis to survive, to be transmitted to new hosts, and to colonize new environments. Therefore, any environmental change should be taken as a warning signal and active surveillance programs should be initiated...
  49. ncbi Genetic (sero) typing of Yersinia pseudotuberculosis
    Tatiana M Bogdanovich
    Department of Medical Biochemistry and Molecular Biology, University of Turku, Finland
    Adv Exp Med Biol 529:337-40. 2003
  50. ncbi Development and testing of a rapid diagnostic test for bubonic and pneumonic plague
    Suzanne Chanteau
    Institut Pasteur de Madagascar, WHO Collaborating Centre for Plague, Antananarivo, Madagascar
    Lancet 361:211-6. 2003
    ..Late diagnosis is one of the major causes of human death and spread of the disease, since it limits the effectiveness of control measures. We aimed to develop and assess a rapid diagnostic test (RDT) for plague...
  51. pmc Plague reappearance in Algeria after 50 years, 2003
    Eric Bertherat
    World Health Organization, Geneva, Switzerland
    Emerg Infect Dis 13:1459-62. 2007
    ..It also demonstrates that the danger of plague reoccurrence is not limited to the currently indexed natural foci...