A O Hueber
- A dominant negative Fas-associated death domain protein mutant inhibits proliferation and leads to impaired calcium mobilization in both T-cells and fibroblastsA O Hueber
Imperial Cancer Research Fund, 44 Lincolns Inn Fields, London WC2A 3PX, United Kingdom
J Biol Chem 275:10453-62. 2000..FADD DN-expressing fibroblasts show a similarly inhibited cell growth and impaired calcium mobilization indicating that the modulation of proliferation and calcium response by death receptors is not cell type-specific...
- Expression of Mad1 in T cells leads to reduced thymic cellularity and impaired mitogen-induced proliferationB Rudolph
Imperial Cancer Research Fund, PO Box 123, 44 Lincoln s Inn Fields, London WC2A 3PX, UK
Oncogene 20:1164-75. 2001..This proliferative defect is not reversed by addition of exogenous IL-2 and is p53-independent. The growth inhibition caused by Mad1 is overcome by expression of active c-Myc...