Philippe Hernigou

Summary

Country: France

Publications

  1. pmc Alumina heads minimize wear and femoral osteolysis progression after isolated simple acetabular revision
    Philippe Hernigou
    Department of Orthopaedic Surgery, University Paris East, UPEC, Hopital Henri Mondor, 94010 Creteil, France
    Clin Orthop Relat Res 470:3094-100. 2012
  2. ncbi History of internal fixation (part 1): early developments with wires and plates before World War II
    Philippe Hernigou
    Orthopaedic Surgery, University Paris East UPEC, Hopital Henri Mondor, 94010, Creteil, France
    Int Orthop . 2016
  3. doi Allografts supercharged with bone-marrow-derived mesenchymal stem cells possess equivalent osteogenic capacity to that of autograft: a study with long-term follow-ups of human biopsies
    Philippe Hernigou
    Orthopaedic Surgery Hôpital Henri Mondor, University Paris East UPEC, 94010, Creteil, France
    Int Orthop 41:127-132. 2017
  4. ncbi History of external fixation for treatment of fractures
    Philippe Hernigou
    Hopital Henri Mondor, Creteil, 94010, France
    Int Orthop . 2016
  5. ncbi Outcome of knee revisions for osteoarthritis and inflammatory arthritis with postero-stabilized arthroplasties: a mean ten-year follow-up with 90 knee revisions
    Philippe Hernigou
    Orthopaedic Surgery, Hopital Henri Mondor, University Paris East UPEC, 94010, Creteil, France
    Int Orthop . 2016
  6. ncbi Dual-mobility implants prevent hip dislocation following hip revision in obese patients
    Philippe Hernigou
    Department of Orthopaedic Surgery, University Paris East UPEC, Hopital Henri Mondor, 94010, Creteil, France
    Int Orthop . 2016
  7. ncbi History of traction for treatment of lower limb fractures
    Philippe Hernigou
    Orthopaedic Surgery, University Paris East UPEC, Hopital Henri Mondor, 94010, Creteil, France
    Int Orthop 40:2635-2641. 2016
  8. doi Talar Osteonecrosis Related to Adult Sickle Cell Disease: Natural Evolution from Early to Late Stages
    Philippe Hernigou
    Hopital Henri Mondor, Creteil, France
    J Bone Joint Surg Am 98:1113-21. 2016
  9. pmc Dual-mobility or Constrained Liners Are More Effective Than Preoperative Bariatric Surgery in Prevention of THA Dislocation
    Philippe Hernigou
    Department of Orthopaedic Surgery, Hospital Henri Mondor, University Paris East, 94010, Creteil, France
    Clin Orthop Relat Res 474:2202-10. 2016
  10. doi Plaster of Paris: the orthopaedic surgeon heritage
    Philippe Hernigou
    Hopital Henri Mondor, University Paris East UPEC, 94010, Creteil, France
    Int Orthop 40:1767-79. 2016

Collaborators

  • Nathalie Chevallier
  • Jérome Allain
  • Sebastien Zilber
  • Frederic Galacteros
  • Itaru Yugué
  • Hao Wu
  • Alexis Nogier
  • Gilles Mathieu
  • Alexandre Poignard
  • Charles Henri Flouzat-Lachaniette
  • Helene Rouard
  • Angelique Lebouvier
  • Julie Leotot
  • Philippe Bierling
  • Jacques Hernigou
  • Yasuhiro Homma
  • Charlie Bouthors
  • Laura Coquelin
  • Mohamed Bouhou
  • François Roubineau
  • Clemence Heyberger
  • Madeleine Cavet
  • Alain Rahmouni
  • Alexandra Alves
  • Charles Henri Flouzat-Lachaniete
  • Philippe Dulvadestin
  • Jérôme Amiaud
  • Louis Ratte
  • Laura Coquelin-Salsac
  • Pierre Layrolle
  • Steffen Queinnec
  • Nicolas Jullien
  • Jean Charles Aurégan
  • Yashiuro Homma
  • Isaac Guissou
  • Jonathan Silvera
  • Laure Picard
  • Charles Henri Flouzat Lachaniette
  • Amir Ghazanfari
  • Gwellaouen Bodivit
  • William Delblond
  • Chaib Younes
  • Anne Fialaire-Legendre
  • Nicolas Dupuy
  • Stephan Roux
  • Julien Amzallag
  • Olivier Pidet
  • Olivier Manicom
  • Martin Mukisi Mukasa
  • Xavier Roussignol
  • Alain Gilton
  • Jean Marty

Detail Information

Publications81

  1. pmc Alumina heads minimize wear and femoral osteolysis progression after isolated simple acetabular revision
    Philippe Hernigou
    Department of Orthopaedic Surgery, University Paris East, UPEC, Hopital Henri Mondor, 94010 Creteil, France
    Clin Orthop Relat Res 470:3094-100. 2012
    ..Patients with THA requiring cup revision for acetabular osteolysis may have a stable stem component without loosening. However, it is unclear whether isolated cup revision halts femoral osteolysis progression...
  2. ncbi History of internal fixation (part 1): early developments with wires and plates before World War II
    Philippe Hernigou
    Orthopaedic Surgery, University Paris East UPEC, Hopital Henri Mondor, 94010, Creteil, France
    Int Orthop . 2016
    ..Nevertheless, Arbuthnot Lane (1892) and Albin Lambotte (1905) are considered to be the founders of this method, which was further developed by Sherman in the first part of the 20th century...
  3. doi Allografts supercharged with bone-marrow-derived mesenchymal stem cells possess equivalent osteogenic capacity to that of autograft: a study with long-term follow-ups of human biopsies
    Philippe Hernigou
    Orthopaedic Surgery Hôpital Henri Mondor, University Paris East UPEC, 94010, Creteil, France
    Int Orthop 41:127-132. 2017
    ..After ten years of follow-up, three types of grafts: those initially loaded with BM-MSCs; dead, irradiated allografts; autografts...
  4. ncbi History of external fixation for treatment of fractures
    Philippe Hernigou
    Hopital Henri Mondor, Creteil, 94010, France
    Int Orthop . 2016
    ..Both Parkhill and Lambotte observed that metal pins inserted into bone were tolerated extremely well by the body. Mainly on the basis of their research findings, many external fixation devices have been and are being developed...
  5. ncbi Outcome of knee revisions for osteoarthritis and inflammatory arthritis with postero-stabilized arthroplasties: a mean ten-year follow-up with 90 knee revisions
    Philippe Hernigou
    Orthopaedic Surgery, Hopital Henri Mondor, University Paris East UPEC, 94010, Creteil, France
    Int Orthop . 2016
    ..Patients with rheumatoid arthritis (RA) and osteoarthritis (OA) may require revision total knee replacement. Few studies have compared post-operative complications, results and risk of re-revision in RA and OA patients...
  6. ncbi Dual-mobility implants prevent hip dislocation following hip revision in obese patients
    Philippe Hernigou
    Department of Orthopaedic Surgery, University Paris East UPEC, Hopital Henri Mondor, 94010, Creteil, France
    Int Orthop . 2016
    ..Revision total hip arthroplasty (THA) is associated with increased rates of dislocation in obese patients. It is not known whether dual-mobility implants decrease dislocation in these patients with obesity...
  7. ncbi History of traction for treatment of lower limb fractures
    Philippe Hernigou
    Orthopaedic Surgery, University Paris East UPEC, Hopital Henri Mondor, 94010, Creteil, France
    Int Orthop 40:2635-2641. 2016
    ..Their concern for the welfare of their patients led to substantial improvements in the treatment of all patients with fractures...
  8. doi Talar Osteonecrosis Related to Adult Sickle Cell Disease: Natural Evolution from Early to Late Stages
    Philippe Hernigou
    Hopital Henri Mondor, Creteil, France
    J Bone Joint Surg Am 98:1113-21. 2016
    ..Forty-five of them (75 tali) were diagnosed with talar osteonecrosis, and this group was evaluated for factors influencing the progression of the disease...
  9. pmc Dual-mobility or Constrained Liners Are More Effective Than Preoperative Bariatric Surgery in Prevention of THA Dislocation
    Philippe Hernigou
    Department of Orthopaedic Surgery, Hospital Henri Mondor, University Paris East, 94010, Creteil, France
    Clin Orthop Relat Res 474:2202-10. 2016
    ....
  10. doi Plaster of Paris: the orthopaedic surgeon heritage
    Philippe Hernigou
    Hopital Henri Mondor, University Paris East UPEC, 94010, Creteil, France
    Int Orthop 40:1767-79. 2016
    ....
  11. ncbi Local transplantation of bone marrow concentrated granulocytes precursors can cure without antibiotics infected nonunion of polytraumatic patients in absence of bone defect
    Philippe Hernigou
    Orthopaedic Surgery, University Paris East UPEC, Hopital Henri Mondor, 94010, Creteil, France
    Int Orthop 40:2331-2338. 2016
    ....
  12. doi History of internal fixation with plates (part 2): new developments after World War II; compressing plates and locked plates
    Philippe Hernigou
    Orthopaedic Surgery, Hopital Henri Mondor, University Paris East UPEC, 94010, Creteil, France
    Int Orthop . 2016
    ..Finally, new devices represented by locking plates increased the stability, contributing to the principles of a more biological osteosynthesis while giving enough stability to allow immediate full weight bearing in some patients...
  13. doi Full weight bearing and dynamisation with Limmed® locked plate fixation accelerates bone regeneration in the volume of opening wedge high tibial osteotomy
    Philippe Hernigou
    Hopital Henri Mondor, Orthopaedic Surgery, Creteil, France
    Int Orthop 39:1295-300. 2015
    ....
  14. doi Medieval orthopaedic history in Germany: Hieronymus Brunschwig and Hans von Gersdorff
    Philippe Hernigou
    Department of Orthopedic Surgery, Hopital Henri Mondor, Creteil, France
    Int Orthop 39:2081-6. 2015
    ..His work covers anatomy, surgery, leprosy, and glossaries of anatomical terms, diseases, and medications...
  15. pmc Ceramic-on-ceramic THA associated with fewer dislocations and less muscle degeneration by preserving muscle progenitors
    Philippe Hernigou
    Hospital Henri Mondor, University Paris East, chirurgie orthopédique, 50, avenue du, Marechal de Lattre de Tassigny, 94000, Paris, Creteil, France
    Clin Orthop Relat Res 473:3762-9. 2015
    ....
  16. doi Reduced levels of mesenchymal stem cells at the tendon-bone interface tuberosity in patients with symptomatic rotator cuff tear
    Philippe Hernigou
    Orthopaedic Surgery, Hospital Henri Mondor, Creteil, France
    Int Orthop 39:1219-25. 2015
    ....
  17. doi Percutaneous injection of bone marrow mesenchymal stem cells for ankle non-unions decreases complications in patients with diabetes
    Philippe Hernigou
    Department of Orthopaedic Surgery, Henri Mondor Hospital, University of Paris, Creteil Cedex, France
    Int Orthop 39:1639-43. 2015
    ..One strategy to mitigate issues with wound healing and infection in diabetic patients is to use a percutaneous technique in which autologous, bone marrow-derived, concentrated cells are injected at the site of non-unions...
  18. doi Bone transplantation and tissue engineering, part IV. Mesenchymal stem cells: history in orthopedic surgery from Cohnheim and Goujon to the Nobel Prize of Yamanaka
    Philippe Hernigou
    Orthopedic Surgery, Hopital Henri Mondor, Creteil, France
    Int Orthop 39:807-17. 2015
    ..This manuscript describes the concept of MSCs from the period when it was relegated to the imagination to the beginning of the twenty-first century and their application in orthopaedic surgery...
  19. doi Long, titanium, cemented stems decreased late periprosthetic fractures and revisions in patients with severe bone loss and previous revision
    Philippe Hernigou
    Hopital Henri Mondor, Orthopedic Surgery, Creteil, France
    Int Orthop 39:639-44. 2015
    ....
  20. doi Bone transplantation and tissue engineering, part III: allografts, bone grafting and bone banking in the twentieth century
    Philippe Hernigou
    Orthopaedic Surgery, Hopital Henri Mondor, Paris, France
    Int Orthop 39:577-87. 2015
    ....
  21. doi Osteonecrosis repair with bone marrow cell therapies: state of the clinical art
    Philippe Hernigou
    Orthopaedic Surgery, University Paris East, Hopital Henri Mondor, 94010 Creteil, France Electronic address
    Bone 70:102-9. 2015
    ..Cell-based therapies might aid in overcoming these deficiencies by providing stem cells and other progenitor cells to potentially improve the local cellular environment in the affected hip...
  22. doi Bone transplantation and tissue engineering. Part II: bone graft and osteogenesis in the seventeenth, eighteenth and nineteenth centuries (Duhamel, Haller, Ollier and MacEwen)
    Philippe Hernigou
    Orthopaedic Surgery, Hopital Henri Mondor, Creteil, France
    Int Orthop 39:193-204. 2015
    ..In response to this challenge, many papers were written to defend each side of the argument. ..
  23. doi Supercharging irradiated allografts with mesenchymal stem cells improves acetabular bone grafting in revision arthroplasty
    Philippe Hernigou
    Hopital Henri Mondor, Orthopedic Surgery, Creteil, France
    Int Orthop 38:1913-21. 2014
    ....
  24. doi Regenerative therapy with mesenchymal stem cells at the site of malignant primary bone tumour resection: what are the risks of early or late local recurrence?
    Philippe Hernigou
    Orthopaedic Surgery, Hopital Henri Mondor, Creteil, France
    Int Orthop 38:1825-35. 2014
    ....
  25. doi Biologic augmentation of rotator cuff repair with mesenchymal stem cells during arthroscopy improves healing and prevents further tears: a case-controlled study
    Philippe Hernigou
    Orthopaedic Surgery, Hopital Henri Mondor, 51 Avenue du Marechal de Lattre de Tassigny, 94010, Creteil, France
    Int Orthop 38:1811-8. 2014
    ..The prevalence of healing and prevention of re-tears were correlated with the number of MSCs received at the tendon-to-bone interface...
  26. doi Bone transplantation and tissue engineering, part I. Mythology, miracles and fantasy: from Chimera to the Miracle of the Black Leg of Saints Cosmas and Damian and the cock of John Hunter
    Philippe Hernigou
    Orthopaedic Surgery, Hopital Henri Mondor, Creteil Cedex, France
    Int Orthop 38:2631-8. 2014
    ..This first paper explains the concept of tissue transplantation from the period when it was relegated to the imagination to the work of the Scottish surgeon and anatomist, John Hunter, who demonstrated the viability of bone allograft. ..
  27. pmc Crutch art painting in the Middle Ages as orthopaedic heritage (part II: the peg leg, the bent-knee peg and the beggar)
    Philippe Hernigou
    Orthopaedic Surgery, Hopital Henri Mondor, Creteil, France
    Int Orthop 38:1535-42. 2014
    ..Pictures and the history of medieval conceptions of disability appear to provide an interesting chronicle of surgery of the peg leg and the bent-knee peg among the representations of cripples and beggars. ..
  28. pmc Crutch art painting in the middle age as orthopaedic heritage (part I: the lepers, the poliomyelitis, the cripples)
    Philippe Hernigou
    Hopital Henri Mondor, University Paris East UPEC, Creteil, France
    Int Orthop 38:1329-35. 2014
    ..The aim of this paper is to give a view of the different crutches used in this period by different people and to observe the influence of this period on the progress of the design of crutches. ..
  29. pmc Cell therapy of hip osteonecrosis with autologous bone marrow grafting
    Philippe Hernigou
    University Paris XII, Hospital Henri Mondor 94010 Creteil, France
    Indian J Orthop 43:40-5. 2009
    ....
  30. pmc Septic arthritis of the hip in adults with sickle cell anemia
    Alexandre Poignard
    University Paris XII, Hopital Henri Mondor, Creteil, France
    Orthop Rev (Pavia) 3:e1. 2011
    ..With an experienced surgical and medical team and multidisciplinary management of these patients undergoing total hip arthroplasty after hip infection, our rate of complications was acceptable...
  31. pmc Percutaneous implantation of autologous bone marrow osteoprogenitor cells as treatment of bone avascular necrosis related to sickle cell disease
    Philippe Hernigou
    Department of Orthopaedic Surgery, 51 Avenue du Marechal de Lattre de Tassigny, 94010 cedex Créteil, France
    Open Orthop J 2:62-5. 2008
    ..Using this mini-invasive high technology surgical treatment in early stages, a joint replacement could be avoided in many patients...
  32. pmc Enlarged transacromial superior approach with reverse shoulder arthroplasty for fractures
    Alexandre Poignard
    University Paris XII, Hospital Henri Mondor, Creteil, France
    Orthop Rev (Pavia) 3:e2. 2011
    ..Reviewing these different steps helps understanding each rotator cuff individual component's contribution to achieve optimal arthroplasty stability and external rotation with a reverse shoulder arthroplasty...
  33. pmc Multifocal joint osteonecrosis in sickle cell disease
    Charles Henri Flouzat-Lachaniete
    Hospital Henri Mondor, 94010 Creteil, France
    Open Orthop J 3:32-5. 2009
    ..In patients with osteonecrosis of the knee, shoulder or ankle, the patients' hip should be evaluated by radiographs or MRI, regardless of whether the hip is symptomatic...
  34. pmc Fifteen year outcome of the ceraver hermes posterior-stabilized total knee arthroplasty: safety of the procedure with experienced and inexperienced surgeons
    Philippe Hernigou
    University Paris XII, Hospital Henri Mondor, 94010 Creteil, France
    Open Orthop J 3:36-9. 2009
    ..The implant used in this series appears particularly safe since the usual complications observed with posterior stabilized arthroplasties were not observed even with young surgeons...
  35. pmc Treatment of infected hip arthroplasty
    Philippe Hernigou
    University Paris XII
    Open Orthop J 4:126-31. 2010
    ..This paper reports the general principles of management, the treatment of acute infection occurring in the postoperative period or later, and the treatment of chronic infection by exchange arthroplasty or resection arthroplasty...
  36. pmc Fixation of the cemented stem: clinical relevance of the porosity and thickness of the cement mantle
    Philippe Hernigou
    Hôpital Henri Mondor 94010 CRETEIL, France
    Open Orthop J 3:8-13. 2009
    ....
  37. pmc Retrieved Unicompartmental Implants with Full PE Tibial Components: The Effects of Knee Alignment and Polyethylene Thickness on Creep and Wear
    Ph Hernigou
    University Paris XII, Hopital Henri Mondor, 94010 Creteil, France
    Open Orthop J 2:51-6. 2008
    ..There is a risk of increased penetration and decreased thickness of the tibial implant when it is too thin, the knee malaligned, and the patient heavy. All these factors increase creep deformation...
  38. pmc Hip hemiarthroplasty: from Venable and Bohlman to Moore and Thompson
    Philippe Hernigou
    Department of Orthopaedic Surgery, Hopital Henri Mondor, Creteil, France
    Int Orthop 38:655-61. 2014
    ..This prosthesis functioned well and later on influenced the development of long stem femoral head prostheses. ..
  39. pmc Design, operative technique and ten-year results of the Hermes™ patellofemoral arthroplasty
    Philippe Hernigou
    Department of Orthopaedic Surgery, Hospital Henri Mondor, Lyon, France
    Int Orthop 38:437-42. 2014
    ..However, there are very few reports of the experience with the modern generation of patellofemoral arthroplasties. The new patellofemoral arthroplasty Hermes design is described. The design and technique of insertion are detailed...
  40. pmc Smith-Petersen and early development of hip arthroplasty
    Philippe Hernigou
    Orthopedic Surgery, Hopital Henri Mondor, Creteil, France
    Int Orthop 38:193-8. 2014
    ..Glass provided a new, smooth surface for movement, and although proving biocompatible, it could not withstand the stresses of walking and quickly failed. Smith-Petersen succeeded in his endeavour by using Vitallium alloy. ..
  41. doi Cancer risk is not increased in patients treated for orthopaedic diseases with autologous bone marrow cell concentrate
    Philippe Hernigou
    Department of Orthopaedic Surgery P H, C H F L, and A P and EFS Cell Therapy Facility N C and H R, University Paris East, Hospital Henri Mondor, 51 Avenue du Marechal de Lattre de Tassigny, 94010 Creteil, France E mail address for P Hernigou
    J Bone Joint Surg Am 95:2215-21. 2013
    ..We investigated the long-term risks for systemic and site-specific cancers in patients who had received autologous bone marrow-derived stromal progenitor cells to treat orthopaedic lesions...
  42. pmc Safety of a novel high tibial osteotomy locked plate fixation for immediate full weight-bearing: a case-control study
    Philippe Hernigou
    Hopital Henri Mondor, Paris, France
    Int Orthop 37:2377-84. 2013
    ..The safety and efficacy of the novel Limmed® system (locked plate fixation) for immediate full weight-bearing after medial opening wedge high tibial osteotomy (HTO) were evaluated in patients with symptomatic varus gonarthrosis...
  43. pmc Benefits of small volume and small syringe for bone marrow aspirations of mesenchymal stem cells
    Philippe Hernigou
    Orthopedic Surgery Hopital Henri Mondor, University Paris East, Creteil, France
    Int Orthop 37:2279-87. 2013
    ..We compared the concentrations of mesenchymal stem cells obtained under normal conditions with two different size syringes...
  44. pmc Earliest times before hip arthroplasty: from John Rhea Barton to Themistocles Glück
    Philippe Hernigou
    Hopital Henri Mondor, Orthopedic Surgery, Creteil, France
    Int Orthop 37:2313-8. 2013
    ..This evaluation reminds us of the ephemeral nature of human industriousness and how medical research and procedures are not isolated developments but correlate to the social, economical, and cultural framework of their time. ..
  45. pmc Ceramic-on-ceramic bearing decreases the cumulative long-term risk of dislocation
    Philippe Hernigou
    Department of Orthopaedic Surgery, University Paris East UPEC, Hopital Henri Mondor, 94010, Creteil, France
    Clin Orthop Relat Res 471:3875-82. 2013
    ..It is also unknown if alumina-on-alumina bearing couples decrease the risk of late dislocation as a result of the absence of wear and osteolysis...
  46. pmc The risk of dislocation after total hip arthroplasty for fractures is decreased with retentive cups
    Philippe Hernigou
    Department of Orthopaedic Surgery, University Paris East, Hopital Henri Mondor, 94010, Creteil, France
    Int Orthop 37:1219-23. 2013
    ..The purpose of the present study was to determine the cumulative risk of dislocation in these patients with fractures and to investigate if retentive cups decrease the risk of dislocation...
  47. pmc Does primary or secondary chondrocalcinosis influence long-term survivorship of unicompartmental arthroplasty?
    Philippe Hernigou
    Department of Orthopedic Surgery, University Paris East UPEC, Hopital Henri Mondor, 94010, Creteil, France
    Clin Orthop Relat Res 470:1973-9. 2012
    ..Several studies suggest more rapid clinical and radiographic progression with CPPD than with OA alone. However, it is unclear whether chondrocalcinosis predisposes to higher risks of progression of arthritis in other compartments...
  48. pmc Constrained liner in neurologic or cognitively impaired patients undergoing primary THA
    Philippe Hernigou
    Department of Orthopaedic Surgery, University Paris XII, Hopital Henri Mondor, 94010, Creteil, France
    Clin Orthop Relat Res 468:3255-62. 2010
    ..The constrained liner reportedly provides stability in patients with recurrent dislocation. However, achieving stability could be offset by early loosening when used in patients with neurologic diseases...
  49. pmc Ceramic-ceramic bearing decreases osteolysis: a 20-year study versus ceramic-polyethylene on the contralateral hip
    Philippe Hernigou
    University Paris XII, Hopital Henri Mondor, Creteil, France
    Clin Orthop Relat Res 467:2274-80. 2009
    ..We found no correlation between the volume of osteolysis and the volume of estimated wear in each couple of friction. Hips with osteolysis had a lower Harris score...
  50. pmc The natural progression of shoulder osteonecrosis related to corticosteroid treatment
    Philippe Hernigou
    Department of Orthopaedic Surgery, University Paris XII, Hopital Henri Mondor, 94010, Creteil, France
    Clin Orthop Relat Res 468:1809-16. 2010
    ..Little is known about the rate and factors of progression of shoulder osteonecrosis (ON) related to corticosteroids...
  51. pmc Opening wedge tibial osteotomy for large varus deformity with Ceraver resorbable beta tricalcium phosphate wedges
    Philippe Hernigou
    Hopital Henri Mondor, University Paris XII, 94010 Creteil, France
    Int Orthop 34:191-9. 2010
    ....
  52. pmc Septic arthritis in adults with sickle cell disease often is associated with osteomyelitis or osteonecrosis
    Philippe Hernigou
    Department of Orthopaedic Surgery, University Paris XII, Hopital Henri Mondor, 51 Avenue du Marechal de Lattre de Tassigny, 94010 Creteil, France
    Clin Orthop Relat Res 468:1676-81. 2010
    ..Septic arthritis is a known complication of sickle cell disease (SCD) in children, and the association with osteomyelitis and osteonecrosis has been described. However, it is unclear whether this association applies to adults...
  53. ncbi Open wedge tibial osteotomy with acrylic bone cement as bone substitute
    P Hernigou
    Hopital Henri Mondor, 51 Avenue du Mal Lattrede, Tassigny, 94010 Creteil, France
    Knee 8:103-10. 2001
    ..We recommend opening wedge tibial osteotomy with acrylic cement bone cement as bone substitute, rigid internal fixation, and early motion for patients who undergo high tibial osteotomy...
  54. pmc High dislocation cumulative risk in THA versus hemiarthroplasty for fractures
    Alexandre Poignard
    Department of Orthopaedic Surgery, University Paris East, UPEC, Hopital Henri Mondor, 94010 Creteil, France
    Clin Orthop Relat Res 469:3148-53. 2011
    ..However, a relatively high frequency of early or late dislocation could reduce the potential benefits with THA...
  55. doi In vivo and in vitro comparison of three different allografts vitalized with human mesenchymal stromal cells
    Laura Coquelin
    EA3952, Cellular and Tissular Bioengineering Laboratory, Paris Est University, Creteil, France
    Tissue Eng Part A 18:1921-31. 2012
    ..As healthcare teams around the world require bone-grafting scaffolds that are safe and easy to store, the TPB allograft appears to be a good compromise between efficient bone formation in vivo and convenient storage at room temperature...
  56. pmc Total THA in adult osteonecrosis related to sickle cell disease
    Philippe Hernigou
    Chirurgie Orthopedique et Traumatologique, Hopital Henri Mondor, University Paris XII, 51 avenue de Lattre de Tassigny, 94010 Creteil, APHP, France
    Clin Orthop Relat Res 466:300-8. 2008
    ..Although THA carries a high risk of complication in patients with sickle cell disease, the benefits for the patient are substantial, and the risk of revision for loosening or infection appeared less than described in previous literature...
  57. pmc Development of a simple procedure for the treatment of femoral head osteonecrosis with intra-osseous injection of bone marrow mesenchymal stromal cells: study of their biodistribution in the early time points after injection
    Angelique Lebouvier
    Universite Paris Est, Faculte de Medecine, Laboratoire de Bioingénierie Cellulaire, Tissulaire et Sanguine, EA3952, 5 rue Gustave Eiffel, 94000, Creteil, France
    Stem Cell Res Ther 6:68. 2015
    ..The impact of this approach was evaluated on one natural pig ONFH...
  58. ncbi Posterior slope of the tibial implant and the outcome of unicompartmental knee arthroplasty
    Philippe Hernigou
    University Paris XII, Hopital Henri Mondor, 94010 Creteil, France Clinique de Dracy, 71640 Dracy Le Fort, France
    J Bone Joint Surg Am 86:506-11. 2004
    ..The purpose of the present study was to assess the effect of the posterior slope on the long-term outcome of unicompartmental arthroplasty in knees with intact and deficient anterior cruciate ligaments...
  59. pmc Stem Cell Therapy for the Treatment of Hip Osteonecrosis: A 30-Year Review of Progress
    Philippe Hernigou
    Department of Orthopaedic Surgery, University Paris East UPEC, Hopital Henri Mondor, Creteil, France
    Clin Orthop Surg 8:1-8. 2016
    ..We undertook a systematic review of the medical literature to examine the progress in cell therapy during the last 30 years for the treatment of early stage osteonecrosis. ..
  60. doi Multifocal osteonecrosis related to corticosteroid: ten years later, risk of progression and observation of subsequent new osteonecroses
    Charles Henri Flouzat-Lachaniette
    Hopital Henri Mondor, 94010, Creteil, France
    Int Orthop 40:669-72. 2016
    ..An analysis of the time-course to other sites of osteonecrosis, as well as the effects of underlying corticosteroid risk factor on the evolution of asymptomatic lesions at the time of diagnosis, is presented...
  61. doi Autologous bone marrow stromal cells are promising candidates for cell therapy approaches to treat bone degeneration in sickle cell disease
    Angelique Lebouvier
    Universite Paris Est, Faculte de Medecine, Laboratoire de Bioingénierie Cellulaire, Tissulaire et Sanguine, EA3952, Creteil, France Etablissement Français du Sang d Ile de France, Unité d Ingénierie et de Thérapie Cellulaire, Creteil, France
    Stem Cell Res 15:584-94. 2015
    ..This work provides important preclinical data that is necessary for the clinical application of expanded BMSCs in advanced therapies and medical products...
  62. pmc The natural progression of adult elbow osteonecrosis related to corticosteroid treatment
    Charles Henri Flouzat-Lachaniette
    Department of Orthopaedic Surgery, University Paris East, Hopital Henri Mondor, 94010 Creteil, France
    Clin Orthop Relat Res 470:3478-82. 2012
    ..In patients with corticosteroid treatment, the elbow is a rare site of osteonecrosis; there is little information about the rate and risk factors of disease progression in symptomatic and asymptomatic elbows...
  63. doi Osteogenic progenitors in bone marrow aspirates have clinical potential for tibial non-unions healing in diabetic patients
    Charles Henri Flouzat-Lachaniette
    Orthopaedic Surgery, Hopital Henri Mondor, University Paris East UPEC, 94010, Creteil, France
    Int Orthop 40:1375-9. 2016
    ....
  64. doi Minimally invasive anterior lumbar interbody fusion for adult degenerative scoliosis with 1 or 2 dislocated levels
    Charles Henri Flouzat-Lachaniette
    Hôpital Henri Mondor AP HP UPEC, Institut du Rachis, Service de Chirurgie Orthopedique et Traumatologique, Creteil, France
    J Neurosurg Spine 23:739-46. 2015
    ..The purpose of this study was to evaluate the midterm outcomes of 1- or 2-level minimally invasive ALIFs in ADS patients with 1- or 2-level dislocations...
  65. doi Platelet lysate coating on scaffolds directly and indirectly enhances cell migration, improving bone and blood vessel formation
    Julie Leotot
    Universite Paris Est, Faculte de Medecine, Laboratoire de Bioingénierie Cellulaire, Tissulaire et Sanguine, Creteil, France
    Acta Biomater 9:6630-40. 2013
    ..This study highlights the potential of functionalizing biomaterials with hPL and shows that this growth factor combination can have synergistic effects leading to enhanced bone and blood vessel formation...
  66. doi Bone-Forming Capacity and Biodistribution of Bone Marrow-Derived Stromal Cells Directly Loaded Into Scaffolds: A Novel and Easy Approach for Clinical Application of Bone Regeneration
    Julie Leotot
    Université Paris Est Créteil, Faculte de Medecine, Laboratoire de Bioingénierie Cellulaire, Tissulaire et Sanguine, Creteil, France
    Cell Transplant 24:1945-55. 2015
    ....
  67. doi New preclinical porcine model of femoral head osteonecrosis to test mesenchymal stromal cell efficiency in regenerative medicine
    Alexandre Poignard
    Faculte de Medecine, Laboratoire de Bioingénierie Cellulaire, Tissulaire et Sanguine, Universite Paris Est, EA3952, Creteil, France
    Int Orthop 38:1837-44. 2014
    ..In order to evaluate new therapeutic approaches to human osteonecrosis of the femoral head (ONFH), this study proposed to improve the existing animal model by developing a new surgically induced pig model...
  68. doi The natural progression of symptomatic humeral head osteonecrosis in adults with sickle cell disease
    Alexandre Poignard
    University Paris Est Creteil, Hopital Henri Mondor, 94010 Creteil, France
    J Bone Joint Surg Am 94:156-62. 2012
    ..However, little is known about the rate of, and the factors influencing, progression of symptomatic shoulder osteonecrosis in patients with this disease...
  69. doi Osteoblastic differentiation of human mesenchymal stem cells with platelet lysate
    Nathalie Chevallier
    EA3952, Cellular and Tissular Bioengineering Laboratory, Henri Mondor Hospital, Paris Est University, France
    Biomaterials 31:270-8. 2010
    ..In conclusion, allogenic human PL accelerates MSC proliferation and enhances MSC osteogenic differentiation...
  70. doi Understanding bone safety zones during bone marrow aspiration from the iliac crest: the sector rule
    Jacques Hernigou
    Department of Orthopedic Surgery, Hopital Henri Mondor, Creteil, France
    Int Orthop 38:2377-84. 2014
    ..The anatomy of the ilium and the structures adjacent to the iliac bone were studied to determine the danger of breach by a trocar introduced into the iliac crest...
  71. doi Anatomy of the ilium for bone marrow aspiration: map of sectors and implication for safe trocar placement
    Jacques Hernigou
    Orthopedic Surgery, Hopital Henri Mondor, Creteil, France
    Int Orthop 38:2585-90. 2014
    ..For example, with an 8-gauge (3.26 mm) trocar, one can consider that if the transverse thickness of the spongiousus bone of the iliac wing is <3 mm, it will be difficult to insert the trocar safely between the two tables...
  72. doi Bone union rate with recombinant human bone morphogenic protein-2 versus autologous iliac bone in PEEK cages for anterior lumbar interbody fusion
    Charles Henri Flouzat-Lachaniette
    Hopital Henri Mondor, AP HP UPEC, Institut du Rachis Service de Chirurgie Orthopédique et Traumatologique, 51, Avenue du Marechal de Lattre de Tassigny, 94010, Creteil Cedex, France
    Int Orthop 38:2001-7. 2014
    ..The objective of this study was to compare bone fusion rates after anterior lumbar interbody fusion (ALIF) between ICBG and rhBMP-2 by examining thin-cut computed tomography (CT) images at the one year follow-up...
  73. ncbi [Hip prosthesis in sickle cell anemia: a delicate affair]
    Philippe Hernigou
    Chirurgie Orthopedique et Traumatologique, Hopital Henri Mondor, Creteil
    Rev Prat 54:1570. 2004
  74. ncbi Treatment ischemic necrosis of the femoral head with vascularized iliac graft in young patients with sickle-cell disease
    Hao Wu
    Orthopedic and Traumatic Department of Henri Mondor Hospital, Creteil, 94010, France
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 19:717-20. 2005
    ..To investigate the therapeutic effects of the vascularized iliac graft for ischemic necrosis of the femoral head in Niger young patients with sickle cell disease...
  75. pmc Tissue bioengineering in orthopedics
    Philippe Hernigou
    Hospital Henri Mondor, University Paris East, Paris, France
    Clin Cases Miner Bone Metab 9:21-3. 2012
    ..This new field is rapidly expanding the armamentarium of orthopedic surgeons in every setting in which bone healing is required. Composites of cells and matrices are at the core of this revolution...
  76. doi The onset time of atracurium is prolonged in patients with sickle cell disease
    Philippe Dulvadestin
    Department of Anesthesia and Intensive Care, Hopital Henri Mondor, Assistance Publique Hopitaux de Paris, Universite Paris, Creteil, France philippe
    Anesth Analg 107:113-6. 2008
    ..The pharmacodynamics of anesthetics may be altered in patients with SCD due to microcirculatory abnormalities or anemia...
  77. doi [Metal/alumine metallosis on tibial osteotomy. A case report]
    G Mathieu
    Service d Orthopedie, Hopital Henri Mondor, 51, Avenue du Marechal de Lattre de Tassigny, 94000 Creteil, France
    Rev Chir Orthop Reparatrice Appar Mot 94:297-300. 2008
    ..Removal of the plate and cleaning of the metallosis zone led to full relief of the pain at one and a half months...
  78. ncbi Unrecognized shoulder joint penetration during fixation of proximal fractures of the humerus
    Philippe Hernigou
    Hopital Henri Mondor, Creteil, France
    Acta Orthop Scand 73:140-3. 2002
    ..Using orthogonal frontal and lateral radiographs, we found unrecognized pin penetration in 8 of 30 patients during fixation of unstable neck fractures of the humerus...
  79. ncbi Patellar impingement following unicompartmental arthroplasty
    P Hernigou
    Henri Mondor Hospital, Creteil, France
    J Bone Joint Surg Am 84:1132-7. 2002
    ..The purpose of the present study was to analyze these complications following unicondylar arthroplasty...
  80. ncbi Routine use of adjusted low-dose oral anticoagulants during the first three postoperative months after hip fracture in patients without comorbidity factors
    P Hernigou
    Hopital Henri Mondor, 94010 Creteil, France
    J Orthop Trauma 15:535-41. 2001
    ..Only one patient developed a postoperative hematoma requiring surgical reoperation. CONCLUSIONS: In the absence of poorly controlled systemic illness, low-dose oral anticoagulants can be used after hip fracture...