Gilles Grateau

Summary

Country: France

Publications

  1. ncbi request reprint Amyloidosis and auto-inflammatory syndromes
    Gilles Grateau
    Service de Medecine Interne, L Hôtel Dieu, Assistance Publique Hopitaux de Paris, Paris, France
    Curr Drug Targets Inflamm Allergy 4:57-65. 2005
  2. ncbi request reprint [Auto-inflammatory syndromes]
    Gilles Grateau
    Service de Medecine Interne, Hopital Tenon, 75970 Paris Cedex 20
    Rev Prat 55:353-9. 2005
  3. ncbi request reprint [Amyloidosis: a model of misfolded protein disorder]
    Gilles Grateau
    Service de Medecine Interne, Hopital Tenon, Paris, France
    Med Sci (Paris) 21:627-33. 2005
  4. pmc The risk of familial Mediterranean fever in MEFV heterozygotes: a statistical approach
    Isabelle Jeru
    UMR_S933, Institut National de la Sante et de la Recherche Medicale, Paris, France
    PLoS ONE 8:e68431. 2013
  5. ncbi request reprint [Hereditary intermittant fever]
    Gilles Grateau
    Service de Medecine Interne, Hotel Dieu, Assistance Publique Hopitaux de Paris
    Presse Med 33:1195-206. 2004
  6. ncbi request reprint The enlarging clinical, genetic, and population spectrum of tumor necrosis factor receptor-associated periodic syndrome
    Catherine Dode
    Hopital Cochin, Institut Cochin, and Institut fédéritif de recherche, de l INSERM, Universite Paris V, Paris, France
    Arthritis Rheum 46:2181-8. 2002
  7. pmc Involvement of the modifier gene of a human Mendelian disorder in a negative selection process
    Isabelle Jeru
    INSERM, U933, Paris, France
    PLoS ONE 4:e7676. 2009
  8. ncbi request reprint Lysozyme amyloidosis: report of 4 cases and a review of the literature
    Brigitte Granel
    Service de Medecine Interne, Hopital Nord, Assistance Publique Hopitaux de Marseille, Marseille, France
    Medicine (Baltimore) 85:66-73. 2006
  9. pmc Prevalence and correlates of metabolic acidosis among patients with homozygous sickle cell disease
    Stéphane Maurel
    Service d Explorations Fonctionnelles, Sickle Cell Centre, and, Internal Medicine Service, Assistance Publique Hopitaux de Paris, Hopital Tenon, Paris, France, Institut National de la Sante et de la Recherche Medicale, UMR_S 1155, Paris, France, Sorbonne Universités, UPMC Univ Paris 06, DHUI2B, Paris, France
    Clin J Am Soc Nephrol 9:648-53. 2014
  10. doi request reprint High lactate dehydrogenase levels at admission for painful vaso-occlusive crisis is associated with severe outcome in adult SCD patients
    Katia Stankovic Stojanovic
    Assistance Publique Hopitaux de Paris, Hopital Tenon, Service de Medecine Interne, Centre de Référence de la Drépanocytose Adulte, Paris, France
    Clin Biochem 45:1578-82. 2012

Collaborators

Detail Information

Publications49

  1. ncbi request reprint Amyloidosis and auto-inflammatory syndromes
    Gilles Grateau
    Service de Medecine Interne, L Hôtel Dieu, Assistance Publique Hopitaux de Paris, Paris, France
    Curr Drug Targets Inflamm Allergy 4:57-65. 2005
    ..Three other types have been recently clinically as well as genetically characterised. A thorough diagnosis is warranted, as clinical and therapeutic management is specific for each of these diseases...
  2. ncbi request reprint [Auto-inflammatory syndromes]
    Gilles Grateau
    Service de Medecine Interne, Hopital Tenon, 75970 Paris Cedex 20
    Rev Prat 55:353-9. 2005
    ..This new group of diseases has already opened new avenues in our understanding of the inflammatory response...
  3. ncbi request reprint [Amyloidosis: a model of misfolded protein disorder]
    Gilles Grateau
    Service de Medecine Interne, Hopital Tenon, Paris, France
    Med Sci (Paris) 21:627-33. 2005
    ....
  4. pmc The risk of familial Mediterranean fever in MEFV heterozygotes: a statistical approach
    Isabelle Jeru
    UMR_S933, Institut National de la Sante et de la Recherche Medicale, Paris, France
    PLoS ONE 8:e68431. 2013
    ..However, heterozygosity might be coincidental in many patients due to the very high rate of mutations in Mediterranean populations...
  5. ncbi request reprint [Hereditary intermittant fever]
    Gilles Grateau
    Service de Medecine Interne, Hotel Dieu, Assistance Publique Hopitaux de Paris
    Presse Med 33:1195-206. 2004
    ....
  6. ncbi request reprint The enlarging clinical, genetic, and population spectrum of tumor necrosis factor receptor-associated periodic syndrome
    Catherine Dode
    Hopital Cochin, Institut Cochin, and Institut fédéritif de recherche, de l INSERM, Universite Paris V, Paris, France
    Arthritis Rheum 46:2181-8. 2002
    ..To characterize the frequency, clinical signs, and genotypic features of tumor necrosis factor receptor-associated periodic syndrome (TRAPS) in a series of 394 patients of various ethnic origins who have recurrent inflammatory syndromes...
  7. pmc Involvement of the modifier gene of a human Mendelian disorder in a negative selection process
    Isabelle Jeru
    INSERM, U933, Paris, France
    PLoS ONE 4:e7676. 2009
    ..Indeed, the SAA1 alpha homozygous genotype and the p.Met694Val homozygous genotype at the MEFV locus are two main risk factors for RA...
  8. ncbi request reprint Lysozyme amyloidosis: report of 4 cases and a review of the literature
    Brigitte Granel
    Service de Medecine Interne, Hopital Nord, Assistance Publique Hopitaux de Marseille, Marseille, France
    Medicine (Baltimore) 85:66-73. 2006
    ....
  9. pmc Prevalence and correlates of metabolic acidosis among patients with homozygous sickle cell disease
    Stéphane Maurel
    Service d Explorations Fonctionnelles, Sickle Cell Centre, and, Internal Medicine Service, Assistance Publique Hopitaux de Paris, Hopital Tenon, Paris, France, Institut National de la Sante et de la Recherche Medicale, UMR_S 1155, Paris, France, Sorbonne Universités, UPMC Univ Paris 06, DHUI2B, Paris, France
    Clin J Am Soc Nephrol 9:648-53. 2014
    ..This study aimed to assess the prevalence of metabolic acidosis and to identify its risk factors and mechanisms...
  10. doi request reprint High lactate dehydrogenase levels at admission for painful vaso-occlusive crisis is associated with severe outcome in adult SCD patients
    Katia Stankovic Stojanovic
    Assistance Publique Hopitaux de Paris, Hopital Tenon, Service de Medecine Interne, Centre de Référence de la Drépanocytose Adulte, Paris, France
    Clin Biochem 45:1578-82. 2012
    ..The aim of this study is to assess biological prognostic factors at the onset of vaso-occlusive crisis (VOC) in adults with sickle cell disease (SCD)...
  11. doi request reprint Autoinflammatory conditions: when to suspect? How to treat?
    Gilles Grateau
    Service de Medecine Interne, Centre de référence des amyloses d origine inflammatoire et de la fièvre méditerranéenne familiale, Hopital Tenon, Assistance Publique Hopitaux de Paris, Universite Paris 6 Pierre et Marie Curie, 4 rue de la Chine, 75970 Paris Cedex 20, France
    Best Pract Res Clin Rheumatol 24:401-11. 2010
    ....
  12. doi request reprint How should we approach classification of autoinflammatory diseases?
    Gilles Grateau
    French Reference Centre for Amyloidosis of Inflammatory Origin and Familial Mediterranean Fever, Hopital Tenon, Assistance Publique Hopitaux de Paris AP HP, 4 rue de la Chine, Paris, F 75020 France
    Nat Rev Rheumatol 9:624-9. 2013
    ..For this purpose, we appeal to the philosophical concepts of family resemblance and signature...
  13. pmc Hemoglobin sickle cell disease complications: a clinical study of 179 cases
    François Lionnet
    Service de Medecine Interne, Hopital Tenon, AP HP, Paris
    Haematologica 97:1136-41. 2012
    ..Surprisingly, few studies have been dedicated to this disease, currently considered to be a mild variant of homozygous sickle cell disease. The aim of this study was to update our knowledge about hemoglobin sickle cell disease...
  14. ncbi request reprint Auto inflammatory syndromes: Diagnosis and treatment
    Katia Stankovic
    Internal Medicine Department, Reference Center for Inflammatory Amyloidosis and Familial Mediterranean Fever, Tenon Teaching Hospital, Assistance Publique Hopitaux de Paris, Paris 6 University, France
    Joint Bone Spine 74:544-50. 2007
    ..New pathophysiological insights have led to the development of promising maintenance treatments designed to reduce the number and severity of the inflammatory attacks and to diminish the risk of secondary amyloidosis...
  15. doi request reprint Role of interleukin-1β in NLRP12-associated autoinflammatory disorders and resistance to anti-interleukin-1 therapy
    Isabelle Jeru
    Universite Pierre et Marie Curie Paris 6, UMR S933, Paris, France
    Arthritis Rheum 63:2142-8. 2011
    ....
  16. pmc Glomerular hyperfiltration in adult sickle cell anemia: a frequent hemolysis associated feature
    Jean Philippe Haymann
    Universite Pierre et Marie Curie, Universite Paris 6, Institut National de la Santé et de la Recherche Médicale Unit 702, Physiology, Paris, France
    Clin J Am Soc Nephrol 5:756-61. 2010
    ..Glomerular damage is a common feature revealed by a microalbuminuria or a macroalbuminuria. Although glomerular hyperfiltration has been described for decades in this population, its prevalence in young adults is unknown...
  17. doi request reprint Concordance between CRP and SAA in familial Mediterranean fever during attack-free period: A study of 218 patients
    Katia Stankovic Stojanovic
    Assistance Publique Hopitaux de Paris, Hopital Tenon, Centre de référence adulte de la fièvre méditerranéenne familiale, Service de Medecine Interne, F 75020 Paris, France Sorbonne Universités, UPMC Universite Paris 06, Département Hospitalo Universitaire I2B, F 75013 Paris, France Electronic address
    Clin Biochem . 2016
    ..In countries where this test is not available, C-reactive protein (CRP), another acute phase reactant, is used instead. However, CRP is low and SAA is increased in some patients and vice versa...
  18. ncbi request reprint A family with gastrointestinal amyloidosis associated with variant lysozyme
    Brigitte Granel
    Service de Medecine Interne, Centre Hospitalier et Universitaire Timone, Marseille, France
    Gastroenterology 123:1346-9. 2002
    ..When gastrointestinal amyloidosis is diagnosed, it is important to determine with precision the nature of the amyloid fibril proteins, because various types of amyloidosis can involve the gastrointestinal tract...
  19. ncbi request reprint Mutational spectrum in the MEFV and TNFRSF1A genes in patients suffering from AA amyloidosis and recurrent inflammatory attacks
    Catherine Dode
    Laboratoire de Biochimie et Genetique Moleculaire, Hopital Cochin, Assistance Publique Hopitaux de Paris AP HP, Paris, France
    Nephrol Dial Transplant 17:1212-7. 2002
    ..In this study we have characterized FMF and TRAPS genotypes in 38 unrelated patients suffering from amyloidosis AA and recurrent inflammatory attacks...
  20. doi request reprint Osteo-articular manifestations of amyloidosis
    Pauline M'bappe
    Service de Medecine Interne, Hopital Tenon, Paris, France
    Best Pract Res Clin Rheumatol 26:459-75. 2012
    ..2-Microglobulin amyloidosis occurs in patients under chronic haemodialysis. It is responsible for CTS, arthralgia and above all a specific destructive spondyloarthropathy. The transthyretin amyloidosis also causes CTS...
  21. doi request reprint Association of hidradenitis suppurativa and familial Mediterranean fever: A case series of 6 patients
    Salam Abbara
    Service de Medecine Interne, Centre de référence des amyloses d origine inflammatoire et de la fièvre méditerranéenne familiale, Hopital Tenon, Assistance Publique Hopitaux de Paris AP HP, Universite Paris 6, Pierre et Marie Curie UPMC, 20, rue de la Chine, 75020 Paris, France
    Joint Bone Spine . 2016
    ..Hidradenitis suppurativa (HS) is an inflammatory cutaneous disease. Those diseases can occur simultaneously among the same individual. Our objective was to describe the features of patients displaying both FMF and HS...
  22. ncbi request reprint Association of the R92Q TNFRSF1A mutation and extracranial deep vein thrombosis in patients with Behçet's disease
    Zahir Amoura
    Hopital Pitie Salpetriere, Paris, France
    Arthritis Rheum 52:608-11. 2005
    ..One of the 2 TNFalpha receptors is TNF receptor superfamily 1A (TNFRSF1A). We searched for R92Q TNFRSF1A mutations in patients with Behçet's disease...
  23. ncbi request reprint [Hereditary recurrent fever syndromes]
    Gilles Grateau
    Medecine Interne, Hopital Tenon, 4, rue de la Chine, 75970 Paris Cedex 20
    Bull Acad Natl Med 189:1235-46; discussion 1246-8. 2005
    ..Proper diagnosis of these entities is needed to begin specific clinical and therapeutic management...
  24. doi request reprint [Auto-inflammatory syndromes and pregnancy]
    Katia Stankovic
    Service de Medecine Interne, Centre de référence des amyloses d origine inflammatoire et de la fièvre méditerranéenne familiale, Hopital Tenon, Assistance Publique Hopitaux de Paris, Universite Paris 6, Paris Cedex 20, France
    Presse Med 37:1676-82. 2008
    ..Breast-feeding is allowed under colchicine with no risk for the baby. There is no indication for systematic amniocentesis in FMF patients treated with colchicine...
  25. ncbi request reprint [Hereditary intermittent fevers, other than familial Mediterranean fevers]
    Gilles Grateau
    Service de médecine interne L Hôtel Dieu 75181 Paris
    Rev Prat 52:155-9. 2002
    ..A thorough diagnosis of these diseases is crucial for appropriate management and treatment...
  26. ncbi request reprint Recurrent Escherichia coli meningitis associated with aspergillar sphenoidal sinusitis
    Amelie Passeron
    Départment de Médecine Interne, Hopital Europeen Georges Pompidou, Paris, France
    Scand J Infect Dis 36:492-3. 2004
    ..We report on the case of a 43-y-old man with 4 recurrent spontaneous episodes of E. coli meningitis related to aspergillar sphenoidal sinusitis. Surgical treatment of sinusitis cured the patient...
  27. ncbi request reprint [What has become of inflammatory amyloidosis?]
    Gilles Grateau
    Service de médecine interne L Hôtel Dieu 75181 Paris
    Rev Prat 53:516-9. 2003
    ..When amyloidosis is progressive in the course of one chronic disease, powerful anti-inflammatory and immunosuppressive drugs can be used...
  28. ncbi request reprint TNFRSF1A-associated periodic syndrome (TRAPS), Muckle-Wells syndrome (MWS) and renal amyloidosis
    Catherine Dode
    Department of Biochemical Genetics, Cochin Hospital, Paris
    J Nephrol 16:435-7. 2003
    ..Missense mutations found in these genes are probably responsible for an improvement in function. Renal AA amyloidosis can also be observed...
  29. ncbi request reprint Is recurrent aseptic meningitis a manifestation of familial Mediterranean fever? A systematic review
    Jean Capron
    Neurology Department, AP HP, Hopital Saint Antoine, Paris, France
    Clin Exp Rheumatol 31:127-32. 2013
    ..Due to the rarity of both diseases, this claim cannot be assessed with epidemiological methods. We therefore decided to perform a systematic review of the literature to assess the number and validity of published case reports...
  30. doi request reprint Dramatic beneficial effect of interleukin-1 inhibitor treatment in patients with familial Mediterranean fever complicated with amyloidosis and renal failure
    Katia Stankovic Stojanovic
    Service de Medecine Interne, Hopital Tenon, Assistance Publique Hopitaux de Paris AP HP, Université Paris 6 Pierre et Marie Curie UPMC, Paris, France
    Nephrol Dial Transplant 27:1898-901. 2012
    ..The aim of this series study was to evaluate anakinra in patients with FMF complicated with amyloidosis and renal failure...
  31. doi request reprint A clinical criterion to exclude the hyperimmunoglobulin D syndrome (mild mevalonate kinase deficiency) in patients with recurrent fever
    Olivier Steichen
    Service de Medecine Interne, Hopital Tenon, 4 rue de la Chine, F 75020 Paris, France
    J Rheumatol 36:1677-81. 2009
    ..Our objective was to define a clinical criterion able to exclude HIDS without the need of genetic testing...
  32. pmc New mutations of CIAS1 that are responsible for Muckle-Wells syndrome and familial cold urticaria: a novel mutation underlies both syndromes
    Catherine Dode
    INSERM EMI 00 05, Institut Cochin, Hopital Cochin, Universite Paris V, Paris, France
    Am J Hum Genet 70:1498-506. 2002
    ..Identification of this gene (or these genes) is likely to have significant therapeutic implications for these severe diseases...
  33. doi request reprint [Amyloidosis AA]
    Katia Stankovic
    Service de Medecine Interne, Hopital Tenon, Assistance Publique Hopitaux de Paris AP HP, Paris Cedex 20, France
    Nephrol Ther 4:281-7. 2008
    ..Current treatment aim at decreasing the inflammatory response; drugs targeting other steps of amyloid deposition are currently developed...
  34. doi request reprint Cystic fibrosis and AA amyloidosis: a survey in the French cystic fibrosis network
    Katia Stankovic Stojanovic
    Centre de Reference pour les Amyloses d Origine Inflammatoire et de la Fièvre Mediterraneenne Familiale, Service de Medecine Interne, Assistance Publique Hopitaux de Paris, Hopital Tenon, Paris France
    Amyloid 21:231-7. 2014
    ..To define the characteristics of CF patients developing AA amyloidosis...
  35. ncbi request reprint Hereditary renal amyloidosis caused by a new variant lysozyme W64R in a French family
    Sophie Valleix
    Laboratoire de Biochimie et Biologie Moleculaire, Hopital Cochin, Assistance Publique Hôpitaux de Paris AP HP et INSERM EMI 00 05, Paris, France
    Kidney Int 61:907-12. 2002
    ..Five proteins--transthyretin, fibrinogen alpha-A chain, apolipoprotein AI, lysozyme, apolipoprotein AII, cystatin C and gelsolin--can be associated with hereditary amyloidosis involving the kidney...
  36. ncbi request reprint Tuberculosis in adult patients with sickle cell disease
    François Lionnet
    centre de la drépanocytose, Hopital Tenon, 4, rue de la Chine, 75020 Paris, France
    J Infect 55:439-44. 2007
    ..We conducted a study to assess the epidemiological and clinical pattern of tuberculosis in adult patients with SCD...
  37. ncbi request reprint Musculoskeletal disorders in secondary amyloidosis and hereditary fevers
    Gilles Grateau
    Service de Medecine Interne, L Hôtel Dieu, I, Place du Parvis Notre Dame, 75181 Paris Cedex 04, France
    Best Pract Res Clin Rheumatol 17:929-44. 2003
    ..Three other types have been recently characterized clinically as well as genetically. A thorough diagnosis is warranted, as clinical and therapeutic management is specific for each of these diseases...
  38. pmc Chronic myelomonocytic leukemia as a cause of fatal uncontrolled inflammation in familial Mediterranean fever
    Fawaz Awad
    Sorbonne Universités, UPMC University Paris 06, INSERM UMR_S933, Hopital Armand Trousseau, Paris, F 75012, France
    Orphanet J Rare Dis 10:76. 2015
    ..Early chemotherapy with interleukin inhibitors could be proposed in such unusual situations. ..
  39. ncbi request reprint Thoracic spinal cord compression indicating Wegener's granulomatosis in a patient with a previous presumptive diagnosis of microscopic polyangiitis
    Claude Bachmeyer
    Service de Medecine Interne, CHU Tenon AP HP, 4 rue de la Chine, 75020 Paris, France
    Joint Bone Spine 74:382-4. 2007
    ..No other site of involvement was found. Slight clinical improvement was observed under immunosuppressive treatment probably because of spinal cord vessels lesions...
  40. ncbi request reprint Clinical and histological characteristics of renal AA amyloidosis: a retrospective study of 68 cases with a special interest to amyloid-associated inflammatory response
    Jérôme Verine
    AP HP, Hopital Saint Louis, Service d Anatomie Pathologique, F 75010 Paris, France
    Hum Pathol 38:1798-809. 2007
    ..AA amyloidosis-related inflammation could partly result from an immune response directed against AA fibrils and could induce amyloid resolution and crescents...
  41. ncbi request reprint Intrafamilial variable phenotypic expression of a CIAS1 mutation: from Muckle-Wells to chronic infantile neurological cutaneous and articular syndrome
    Véronique Hentgen
    Departement de medecine de l Enfant et de l Adolescent, Service de Dermatologie, Centre Hospitalier Regional et Universitaire de Rennes, Rennes, France
    J Rheumatol 32:747-51. 2005
    ..Clinical and genetic observations suggest that Muckle-Wells syndrome, CINCA, and familial cold urticaria are various phenotypic expressions of the same disease...
  42. ncbi request reprint Diagnostic tools for amyloidosis
    Eric Hachulla
    Internal Medicine Department, Centre Hospitalier Regional et Universitaire, Hopital Claude Huriez, 59037, Lille Cedex, France
    Joint Bone Spine 69:538-45. 2002
    ..Deposits are usually seen in the liver and spleen. SAP component scintigraphy can provide support for the diagnosis of amyloidosis in patients with negative histological studies. Tissue retention of radioactivity predicts survival...
  43. ncbi request reprint [Familial Mediterranean fever and other hereditary recurrent inflammatory diseases]
    Gilles Grateau
    Presse Med 34:907. 2005
  44. ncbi request reprint Localized amyloidosis: a survey of 35 French cases
    Marc Paccalin
    Department of Internal Medicine, Hopital Jean Bernard, BP 577, 86021, Poitiers Cedex, France
    Amyloid 12:239-45. 2005
    ..Such patients should be referred to specialist centers for further evaluation. Management requires close follow-up to exclude recurrence and to determine the appropriate symptomatic treatment...
  45. ncbi request reprint Prevalence and distribution of MEFV mutations among Arabs from the Maghreb patients suffering from familial Mediterranean fever
    Latifa Belmahi
    Laboratoire de Genetique, Institut National D Hygiene, 11400 Rabat, Morocco
    C R Biol 329:71-4. 2006
    ..We estimated the frequency of MEFV mutation carriers among the Arab Maghrebian population at around 1%, which is significantly lower than in non-Ashkenazi Jews, Armenians or Turks...
  46. ncbi request reprint Analysis of the NOD2/CARD15 gene in patients affected with the aseptic abscesses syndrome with or without inflammatory bowel disease
    Marc François Jean André
    INSERM, U384, Clermont Ferrand, 63001, France
    Dig Dis Sci 53:490-9. 2008
    ..It is associated in two cases out of three with inflammatory bowel disease (IBD), and in particular with CD. We wanted to assess if changes on gene NOD2/CARD15 could contribute to the development of AA in patients with and without IBD...
  47. ncbi request reprint Transthyretin mutation (TTRGly47Ala) associated with familial amyloid polyneuropathy in a French family
    Nadine Magy
    Service de médecine interne et immunologie clinique, Centre Hospitalo Universitaire Jean Minjoz, Besancon, France
    Amyloid 9:272-5. 2002
    ..This mutation (G47A) was previously identified in two different families of Italian origin both of which had FAP and cardiomyopathy. Here we report the first identification of this mutation in a non-Italian family...
  48. ncbi request reprint Allogenic bone marrow transplantation: not a treatment yet for familial Mediterranean fever
    Isabelle Touitou
    Blood 102:409. 2003
  49. ncbi request reprint Underdiagnosed amyloidosis: amyloidosis of lysozyme variant
    Brigitte Granel
    Am J Med 118:321-2. 2005