Bruno Giraudeau

Summary

Country: France

Publications

  1. ncbi Model mis-specification and overestimation of the intraclass correlation coefficient in cluster randomized trials
    Bruno Giraudeau
    INSERM CIC 202, Faculte de Medecine, Tours, France
    Stat Med 25:957-64. 2006
  2. ncbi [The cluster-randomized trial]
    Bruno Giraudeau
    INSERM CIC 202, Faculte de Medecine, 2bis, boulevard Tonnelle, 37032 Tours Cedex, France
    Med Sci (Paris) 20:363-6. 2004
  3. doi Comparison of degree of stenosis and plaque volume for the assessment of carotid atherosclerosis using 2-D ultrasound
    Axel de Labriolle
    Departement de Cardiologie, Centre Hospitalier Universitaire, Tours, France
    Ultrasound Med Biol 35:1436-42. 2009
  4. ncbi Enalapril/amlodipine combination in cyclosporine-treated renal transplant recipients: a prospective randomized trial
    Jean Michel Halimi
    Department of Nephrology and Clinical Immunology, Francois Rabelais University, CHRU Bretonneau, Tours, France
    Clin Transplant 21:277-84. 2007
  5. ncbi Contrast-enhanced sonography helps in discrimination of benign from malignant adnexal masses
    Henri Marret
    Department of Gynecology and Obstetrics, Fetal Medicine, and Human Reproduction, Bretonneau University Hospital, Tours, France
    J Ultrasound Med 23:1629-39; quiz 1641-42. 2004
  6. ncbi Does data rounding-off influence reproducibility index estimates?
    Bruno Giraudeau
    INSERM CIC 202, Faculte de Medecine, 2bis Bd Tonnelle, 37032 Tours Cedex, France
    J Appl Meas 6:100-8. 2005
  7. ncbi A retrospective multicentre study comparing myomectomy by laparoscopy and laparotomy in current surgical practice. What are the best patient selection criteria?
    Henri Marret
    Département de gynécologie, Obstétrique, Medecine Foetale et Reproduction Humaine, Centre Hospitalier Universitaire Hôpital Bretonneau, 2 Bd Tonnelle, 37044 Tours Cedex 1, France
    Eur J Obstet Gynecol Reprod Biol 117:82-6. 2004
  8. ncbi The risk of hypertension in men: direct and indirect effects of chronic smoking
    Jean Michel Halimi
    Centre de Recherche Clinique, Faculte de Medecine, Tours, France
    J Hypertens 20:187-93. 2002
  9. pmc Diet, cancer, and the lipidome
    Philippe Bougnoux
    INSERM E 0211, University Hospital of Tours, 2 boulevard Tonnelle, 37044 Tours Cedex, France
    Cancer Epidemiol Biomarkers Prev 15:416-21. 2006
  10. ncbi Living with a functioning kidney transplant at 74 yr or older: a national epidemiological study
    Matthias Buchler
    Department of Nephrology and Clinical Immunology, CHU Bretonneau, Tours, France
    Clin Transplant 18:681-5. 2004

Detail Information

Publications60

  1. ncbi Model mis-specification and overestimation of the intraclass correlation coefficient in cluster randomized trials
    Bruno Giraudeau
    INSERM CIC 202, Faculte de Medecine, Tours, France
    Stat Med 25:957-64. 2006
    ..This study demonstrates that estimating this parameter with one-way ANOVA and an underlying mixed-effects statistical model leads to biased estimates. The bias depends on the effect size of the studied treatment...
  2. ncbi [The cluster-randomized trial]
    Bruno Giraudeau
    INSERM CIC 202, Faculte de Medecine, 2bis, boulevard Tonnelle, 37032 Tours Cedex, France
    Med Sci (Paris) 20:363-6. 2004
    ..A cluster randomized trial is thus justified only if the context or the question of interest imposes it and biostatistical issues have then to be handled in a rigorous way...
  3. doi Comparison of degree of stenosis and plaque volume for the assessment of carotid atherosclerosis using 2-D ultrasound
    Axel de Labriolle
    Departement de Cardiologie, Centre Hospitalier Universitaire, Tours, France
    Ultrasound Med Biol 35:1436-42. 2009
    ..The absence of correlation between the PVI and the %ST confirm that these two parameters describe two different processes of the atheromatous development...
  4. ncbi Enalapril/amlodipine combination in cyclosporine-treated renal transplant recipients: a prospective randomized trial
    Jean Michel Halimi
    Department of Nephrology and Clinical Immunology, Francois Rabelais University, CHRU Bretonneau, Tours, France
    Clin Transplant 21:277-84. 2007
    ..Most hypertensive renal transplant recipients require two or more antihypertensive medications to achieve blood pressure control. However, which medications must be combined is still a matter of debate...
  5. ncbi Contrast-enhanced sonography helps in discrimination of benign from malignant adnexal masses
    Henri Marret
    Department of Gynecology and Obstetrics, Fetal Medicine, and Human Reproduction, Bretonneau University Hospital, Tours, France
    J Ultrasound Med 23:1629-39; quiz 1641-42. 2004
    ..To investigate the potential efficacy of real-time contrast-enhanced power Doppler sonography in the differentiation of benign and malignant adnexal masses in a pilot study...
  6. ncbi Does data rounding-off influence reproducibility index estimates?
    Bruno Giraudeau
    INSERM CIC 202, Faculte de Medecine, 2bis Bd Tonnelle, 37032 Tours Cedex, France
    J Appl Meas 6:100-8. 2005
    ..Therefore, in most practical situations the consequences of rounding-off data on the estimation of reproducibility levels can be ignored...
  7. ncbi A retrospective multicentre study comparing myomectomy by laparoscopy and laparotomy in current surgical practice. What are the best patient selection criteria?
    Henri Marret
    Département de gynécologie, Obstétrique, Medecine Foetale et Reproduction Humaine, Centre Hospitalier Universitaire Hôpital Bretonneau, 2 Bd Tonnelle, 37044 Tours Cedex 1, France
    Eur J Obstet Gynecol Reprod Biol 117:82-6. 2004
    ..To determine the differences in myoma characteristics before laparoscopic myomectomy (LM) and abdominal myomectomy (AM) and to compare outcomes in current practice...
  8. ncbi The risk of hypertension in men: direct and indirect effects of chronic smoking
    Jean Michel Halimi
    Centre de Recherche Clinique, Faculte de Medecine, Tours, France
    J Hypertens 20:187-93. 2002
    ..To assess the risk of hypertension associated with smoking status...
  9. pmc Diet, cancer, and the lipidome
    Philippe Bougnoux
    INSERM E 0211, University Hospital of Tours, 2 boulevard Tonnelle, 37044 Tours Cedex, France
    Cancer Epidemiol Biomarkers Prev 15:416-21. 2006
    ....
  10. ncbi Living with a functioning kidney transplant at 74 yr or older: a national epidemiological study
    Matthias Buchler
    Department of Nephrology and Clinical Immunology, CHU Bretonneau, Tours, France
    Clin Transplant 18:681-5. 2004
    ..Renal function in this group of patients was good and quality of life seemed excellent. Cardiovascular disease and malignancies were the main co-morbid conditions...
  11. ncbi Routine ultrasonography in melanoma follow-up?
    Laurent Machet
    Department of Dermatology, University Hospital, Hopital Trousseau, 37044 Tours Cedex 1, France
    Lancet Oncol 6:2; discussion 3. 2005
  12. doi Preoperative measurement of thickness of cutaneous melanoma using high-resolution 20 MHz ultrasound imaging: A monocenter prospective study and systematic review of the literature
    Laurent Machet
    Universite Francois Rabelais de Tours, UMR INSERM U CNRS ERL, France
    Ultrasound Med Biol 35:1411-20. 2009
    ..Preoperative high-resolution ultrasound is a noninvasive examination that can help in choosing appropriate surgical margins and should reduce the need of partial or excisional biopsy before surgery, and the need for further re-excision...
  13. doi Absence of inferior labial and lingual frenula in Ehlers-Danlos syndrome: a minor diagnostic criterion in French patients
    Laurent Machet
    INSERM U930 CNRS ERL 3106, Universite Francois Rabelais, Tours, France
    Am J Clin Dermatol 11:269-73. 2010
    ..The absence of the lingual and inferior labial frenula was reported to be a useful diagnostic tool in a series of 12 patients with classical and hypermobile EDS. However, two further reports have contested the value of this sign...
  14. doi Iatrogenic events contributing to ICU admission: a prospective study
    Emmanuelle Mercier
    Service de Reanimation Medicale, Universite Francois Rabelais, Hopital Bretonneau, CHRU, 37044, Tours Cedex 9, France
    Intensive Care Med 36:1033-7. 2010
    ..To determine the incidence, risk factors, severity, and preventability of iatrogenic events (IEs) as a cause of intensive care unit (ICU) admission...
  15. pmc Amoxicillin/clavulanic acid is ineffective at preventing otitis media in children with presumed viral upper respiratory infection: a randomized, double-blind equivalence, placebo-controlled trial
    Elisabeth Autret-Leca
    Department of Clinical Pharmacology, Hospital Bretonneau and University François Rabelais, Tours, France
    Br J Clin Pharmacol 54:652-6. 2002
    ..To assess the equivalence of amoxicillin/clavulanic acid and placebo in the prevention of acute otitis media in children at high risk of acute otitis media who develop upper respiratory tract infection...
  16. ncbi Simultaneous estimation of cyclosporin and mycophenolic acid areas under the curve in stable renal transplant patients using a limited sampling strategy
    Chantal Le Guellec
    Department of Pharmacology, Tours University Hospital, France
    Eur J Clin Pharmacol 57:805-11. 2002
    ..It is the method of choice for mycophenolic acid (MPA). The objective of this study was to develop a limited sampling strategy for simultaneous estimation of CsA and MPA AUCs in long-term renal transplant patients...
  17. pmc Dead space closure with quilting suture versus conventional closure with drainage for the prevention of seroma after mastectomy for breast cancer (QUISERMAS): protocol for a multicentre randomised controlled trial
    Lobna Ouldamer
    Department of Gynecology, CHRU de Tours, Tours, France INSERM Unit 1069, Tours, France
    BMJ Open 6:e009903. 2016
    ..The aim of this trial is to compare seroma formation using quilting suture versus conventional closure with drainage in patients undergoing mastectomy...
  18. doi Deficits in information transfer between hospital-based and primary-care physicians, the case of kidney disease: a cross-sectional study
    Benedicte Sautenet
    Service de néphrologie immunologie clinique, CHU de Tours, Hopital Bretonneau, 37044, Tours, France
    J Nephrol 28:563-70. 2015
    ..Whether it is notified in patients' hospital discharge summary (HDS) is presently largely unknown...
  19. pmc Design effect in multicenter studies: gain or loss of power?
    Emilie Vierron
    INSERM, CIC 202, Tours, France
    BMC Med Res Methodol 9:39. 2009
    ..Such a clustering is usually assessed through the design effect, defined as a ratio of two variances. The aim of this work was to describe and understand situations where the design effect involves a gain or a loss of power...
  20. ncbi Sample size calculation for multicenter randomized trial: taking the center effect into account
    Emilie Vierron
    INSERM CIC 202, Universite Francois Rabelais, Tours, CHRU de Tours, France
    Contemp Clin Trials 28:451-8. 2007
    ..This work allows for adjusting and reducing the sample size according to the magnitude of the center effect and leads to a better consistency in the conduct of multicenter randomized trials...
  21. ncbi Conjugated linoleic acid content in breast adipose tissue of breast cancer patients and the risk of metastasis
    Veronique Chajes
    Inserm Emi U 0211, IFR 120, Tours Bretonneau, Tours, France
    Nutr Cancer 45:17-23. 2003
    ....
  22. doi Propensity score methods for estimating relative risks in cluster randomized trials with low-incidence binary outcomes and selection bias
    Clémence Leyrat
    Inserm U1153, Paris, France INSERM CIC 1415, Tours, France CHRU de Tours, Tours, France
    Stat Med 33:3556-75. 2014
    ....
  23. doi Dichotomizing a continuous outcome in cluster randomized trials: impact on power
    Agnès Caille
    INSERM, UMR 738, Paris, France
    Stat Med 31:2822-32. 2012
    ..Loss of power is reduced with increased initial continuous-outcome ICC and/or prevalence of success for the dichotomized outcome approaching 50%...
  24. doi Tolerance of low-frequency ultrasound sonophoresis: a double-blind randomized study on humans
    Annabel Maruani
    University François Rabelais Tours, Inserm U930 Tours, Service de Dermatologie, CHRU Tours, France
    Skin Res Technol 18:151-6. 2012
    ..Sonophoresis [low-frequency ultrasound (US)] has been used in animals and in vitro to investigate enhanced percutaneous absorption of drugs. No study focused on its clinical human tolerance has been published as yet...
  25. ncbi Assessment of cyclic changes of microvessels in ovine ovaries using Sonovue contrast-enhanced ultrasound
    Henri Marret
    Department of Gynecology, Obstetrics, Fetal Medicine and Human Reproduction, Bretonneau University Hospital, Tours, France
    Ultrasound Med Biol 32:163-9. 2006
    ..Thus, using these parameters in premenopausal women will allow more accurate detection of vascular modifications that may be associated with ovarian cancer...
  26. ncbi Association of donor TNFRSF6 (FAS) gene polymorphism with acute rejection in renal transplant patients: a case-control study
    Sandrine Cappellesso
    UPRES EA 3249 Cellules Hématopoïétiques, Hémostase et Greffe, Universite de Tours, Faculte de Medecine, and Laboratoire d Immunologie and Service de Néphrologie et Immunologie Clinique, CHRU de Tours, Tours Cedex, France
    Nephrol Dial Transplant 19:439-43. 2004
    ....
  27. ncbi Nasal carriage of methicillin-resistant staphylococcus aureus in vascular surgery
    Virginie Morange-Saussier
    Department of Bacteriology and Hospital Hygiene, Trousseau University Hospital, Tours, France
    Ann Vasc Surg 20:767-72. 2006
    ..French recommendations issued for cardiac and orthopedic surgery by the consensus conference on preoperative management of infectious risk on March 5, 2004, should be extended to vascular surgery...
  28. doi Quilting Suture of Mastectomy Dead Space Compared with Conventional Closure with Drain
    Lobna Ouldamer
    Department of Gynecology, CHRU de Tours, Tours, France
    Ann Surg Oncol 22:4233-40. 2015
    ..This study was designed to compare conventional closure with a drain and quilting suture of mastectomy dead space for preventing wound seroma...
  29. pmc Study design and quality of reporting of randomized controlled trials of chronic idiopathic or autoimmune urticaria: review
    Elodie Le Fourn
    CHRU de Tours, Service de Dermatologie, Tours, France
    PLoS ONE 8:e70717. 2013
    ..Numerous recommendations with heterogeneous conclusions have been published. We wondered whether such heterogeneous conclusions were linked to the quality of published studies and their reporting...
  30. doi Second-trimester uterine artery Doppler, PlGF, sFlt-1, sEndoglin, and lipid-related markers for predicting preeclampsia in a high-risk population
    Caroline Diguisto
    Department of Obstetrics, University Hospital Tours, Tours, France University François Rabelais, Tours, France
    Prenat Diagn 33:1070-4. 2013
    ..This study aimed to determine if screening for preeclampsia could be improved between 20 and 24 weeks of gestation by uterine artery Doppler (UAD), biomarkers and lipid-related markers...
  31. pmc Mixing nulliparous and multiparous women in randomised controlled trials of preeclampsia prevention is debatable: evidence from a systematic review
    Emmanuel Simon
    INSERM, UMR S 738, Paris, France
    PLoS ONE 8:e66677. 2013
    ..Nulliparity is a major risk factor of preeclampsia investigated in numerous trials of its prevention...
  32. pmc Peer review of grant applications: a simple method to identify proposals with discordant reviews
    Bruno Giraudeau
    Institut National de la Sante et de la Recherche Medicale, Tours, France
    PLoS ONE 6:e27557. 2011
    ..We propose a simple method to identify such proposals. Our approach is based on the intraclass correlation coefficient, which is usually used in assessing agreement in studies with continuous ratings...
  33. doi Center effect on ankle-brachial index measurement when using the reference method (Doppler and manometer): results from a large cohort study
    Emilie Vierron
    INSERM, CIC 202, Tours, France
    Am J Hypertens 22:718-22. 2009
    ..We aimed to assess, in a French multicenter cohort, the center effect associated with arterial pressure (AP) and ABI measurements using the reference method and using a semiautomatic device...
  34. ncbi Revascularization algorithm in acute STEMI should take into account age
    Axel de Labriolle
    Departement de Cardiologie, Centre Hospitalier Universitaire Tours, Tours, France
    Cardiovasc Revasc Med 8:90-3. 2007
    ..Moreover, there is a lack of data regarding the effect of time to treatment (TT) on prognosis of STEMI in elderly patients...
  35. pmc Relationship between 5-fluorouracil exposure and outcome in patients receiving continuous venous infusion with or without concomitant radiotherapy
    Maud Beneton
    Department of Pharmacology, CHRU de Tours, Tours, France
    Br J Clin Pharmacol 64:613-21. 2007
    ..We investigated the plasma concentration-effect relationship for this regimen, with the aim of developing recommendations for dose adjustment...
  36. doi Avoidability of adverse drug reactions spontaneously reported to a French regional drug monitoring centre
    Annie Pierre Jonville-Bera
    Pharmacoepidemiology and Clinical Pharmacology Unit Regional Drug Monitoring Centre, CHRU de Tours, Tours, France
    Drug Saf 32:429-40. 2009
    ..Adverse drug reactions (ADRs) are now recognized as a major category of iatrogenic illness in terms of morbidity and mortality...
  37. ncbi [Correcting the critical reading test of the national ranking examination]
    Annabel Maruani
    Faculte de Medecine, Universite Francois Rabelais, Tours
    Presse Med 36:571-4. 2007
    ..The aim of our study was to assess the consistency of grading between this two-part test (critical analysis and summarizing, analyzed separately), and the more classic tests...
  38. pmc A multicentre case-control study of nonsteroidal anti-inflammatory drugs as a risk factor for severe sepsis and septic shock
    Annick Legras
    Department of Intensive Care Unit, University Hospital of Tours, boulevard Tonnelle, 37044 Tours, France
    Crit Care 13:R43. 2009
    ..We aimed to establish whether the use of nonsteroidal anti-inflammatory drugs (NSAIDs) during evolving bacterial community-acquired infection in adults is associated with severe sepsis or septic shock...
  39. ncbi Renal arterial resistance index
    Bruno Giraudeau
    N Engl J Med 349:1573-4; author reply 1573-4. 2003
  40. pmc Planning a cluster randomized trial with unequal cluster sizes: practical issues involving continuous outcomes
    Lydia Guittet
    Département d Epidémiologie, Biostatistique et Recherche Clinique, Groupe Hospitalier Bichat Claude Bernard AP HP, Université Xavier Bichat, Paris, France
    BMC Med Res Methodol 6:17. 2006
    ..At the planning stage, sample size calculations usually consider an average cluster size without taking into account any potential imbalance in cluster size. However, there may exist high discrepancies in cluster sizes...
  41. ncbi Ovine model to evaluate ovarian vascularization by using contrast-enhanced sonography
    Henri Marret
    Department of Gynecology, Obstetrics, Fetal Medicine and Human Reproduction, Bretonneau University Hospital, 2 boulevard Tonnelle, 37044 Tours cedex 1 France
    Comp Med 55:150-5. 2005
    ..001), but the enhancement time was the same. We concluded that the sheep is an excellent animal model to illustrate microcirculation enhancement by using Sonovue to demonstrate ovarian vascular changes...
  42. ncbi Antipyretic drug use in children in French office based medical practice
    Jean Deligne
    CANAM, Caisse Nationale d Assurance Maladie des Professions Indépendantes, France
    Pharmacoepidemiol Drug Saf 16:812-7. 2007
    ..To analyse antipyretics (APs) prescriptions profile in children, particularly the frequency of AP combinations...
  43. pmc A priori postulated and real power in cluster randomized trials: mind the gap
    Lydia Guittet
    Département d Epidémiologie, Biostatistique et Recherche Clinique, Groupe Hospitalier Bichat Claude Bernard AP HP Université Paris 7, Paris, France
    BMC Med Res Methodol 5:25. 2005
    ..The intraclass correlation coefficient (ICC) defines the clustering effect and be specified during planning. The aim of this work is to study the influence of the ICC on power in cluster randomized trials...
  44. ncbi The methods for handling missing data in clinical trials influence sample size requirements
    Guy Robert Auleley
    université Paris V René Descartes, Faculté de Médecine Cochin Port Royal and Clinique de Rhumatologie, Hopital Cochin, AP HP, Paris, France
    J Clin Epidemiol 57:447-53. 2004
    ..Results of studies estimating osteoarthritis progression may be affected by missing values. In clinical trials assessing disease-modifying osteoarthritis drugs, sample sizes should be calculated using close estimates of outcome variables...
  45. ncbi Methodological differences in clinical trials evaluating nonpharmacological and pharmacological treatments of hip and knee osteoarthritis
    Isabelle Boutron
    Département d Epidémiologie, Biostatistique et Recherche Clinique, Groupe Hospitalier Bichat Claude Bernard, Assistance Publique des Hopitaux de Paris, Faculte Xavier Bichat, Universite Paris VII, Paris, France
    JAMA 290:1062-70. 2003
    ....
  46. pmc Frequency of adverse drug reactions in children: a prospective study
    Annie Pierre Jonville-Bera
    Department of Clinical Pharmacology and Regional Drug Monitoring Centre, University Hospital of Tours, 2 Boulevard Tonellé, 37044 Tours Cedex, France
    Br J Clin Pharmacol 53:207-10. 2002
    ..To assess the frequency of adverse drug reactions (ADRs) in children in France...
  47. ncbi Blinding was judged more difficult to achieve and maintain in nonpharmacologic than pharmacologic trials
    Isabelle Boutron
    INSERM EMI 03 57, Département d Epidémiologie, Biostatistique et Recherche Clinique, Groupe Hospitalier Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Faculte Xavier Bichat, Universite Paris 7, France
    J Clin Epidemiol 57:543-50. 2004
    ..To compare the feasibility of blinding and the perceived risk of unblinding in trials evaluating pharmacologic (PT) and nonpharmacologic treatments (NPT) of hip or knee osteoarthritis...
  48. ncbi Safety study of intraarticular injection of interleukin 1 receptor antagonist in patients with painful knee osteoarthritis: a multicenter study
    Xavier Chevalier
    Department of Rheumatology, Hospital Henri Mondor, University Paris XII, Paris, France
    J Rheumatol 32:1317-23. 2005
    ..In animal models of OA, IL-1 blockade by IL-1 receptor antagonist (IL-1Ra) can slow the progression of disease. We examined the safety of intraarticular (IA) injections of recombinant human IL-1Ra in patients with knee OA...
  49. ncbi A checklist to evaluate a report of a nonpharmacological trial (CLEAR NPT) was developed using consensus
    Isabelle Boutron
    INSERM U738, Paris, France
    J Clin Epidemiol 58:1233-40. 2005
    ..To develop a checklist of items measuring the quality of reports of randomized clinical trials (RCTs) assessing nonpharmacological treatments (NPTs)...
  50. ncbi Reporting of drug tolerance in randomized clinical trials: when data conflict with authors' conclusions
    Annie Pierre Jonville-Bera
    Ann Intern Med 144:306-7. 2006
  51. ncbi Quality of reporting of noninferiority and equivalence randomized trials
    Anne Le Henanff
    Institut National de la Santé et de la Recherche Médicale INSERM U738, Paris, France
    JAMA 295:1147-51. 2006
    ..These study objectives imply particular planning and analysis...
  52. ncbi Treatment of chronic hepatitis C in patients unresponsive to interferon. Interest of re-treatment combining interferon induction therapy and ribavirin (a multicenter pilot study)
    Xavier Causse
    Service d Hepato Gastroenterologie, CHR La Source, BP 6709, 45067 Orleans Cedex 2
    Gastroenterol Clin Biol 29:117-21. 2005
    ....
  53. ncbi Predictive factors for fibroids recurrence after uterine artery embolisation
    Henri Marret
    Department of Gynaecology, Obstetrics, Fetal Medicine and Human Reproduction, Bretonneau University Hospital, 2 boulevard Tonnelle, 37044 Tours Cedex 1, France
    BJOG 112:461-5. 2005
    ..To assess clinical failure and symptom recurrence after uterine artery embolisation (UAE) and to define predictive factors...
  54. ncbi [Impact of a recall campaign of the rules of the elimination of the injection equipment used for the treatment of hepatitis C in the centre region of France]
    Louis d'Alteroche
    Gastroenterol Clin Biol 30:492-3. 2006
  55. pmc Reporting of radiographic methods in randomised controlled trials assessing structural outcomes in rheumatoid arthritis
    Gabriel Baron
    Département d Epidémiologie Biostatistique et Recherche Clinique, INSERM, U738, Groupe Hospitalier Bichat Claude Bernard, 46 rue Henri Huchard, 75018 Paris, France
    Ann Rheum Dis 66:651-7. 2007
    ....
  56. ncbi Anisotropy changes in post-menopausal osteoporosis: characterization by a new index applied to trabecular bone radiographic images
    Christine Chappard
    INSERM ERIT M0101, CHR Orleans, 1 rue Porte Madeleine, 45032 Orleans Cedex 1, France
    Osteoporos Int 16:1193-202. 2005
    ..These data suggest that we can improve the fracture risk evaluation by adding information related to the directional organization of trabecular bone derived from the FFT spectrum on conventional radiographic images...
  57. ncbi Reporting of harm in randomized, controlled trials of nonpharmacologic treatment for rheumatic disease
    Morgane Ethgen
    Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France
    Ann Intern Med 143:20-5. 2005
    ..Reports of clinical trials usually emphasize benefits and give less attention to harms...
  58. ncbi Lack of association between rifampicin plasma concentration and treatment-related side effects in osteoarticular infections
    France Roblot
    CHRU de Tours, Service des Maladies Infectieuses, 2 boulevard Tonnelle, 37044 Tours Cedex, France
    Fundam Clin Pharmacol 21:363-9. 2007
    ..GSE occur frequently in patients receiving rifampicin for osteoarticular infection but without an association with rifampicin plasma concentrations. Thus, therapeutic drug monitoring of rifampicin is irrelevant in the management of GSE...
  59. doi Missing data in randomized controlled trials of rheumatoid arthritis with radiographic outcomes: a simulation study
    Gabriel Baron
    AP HP, Hopital Bichat, Biostatistique et Recherche Clinique, INSERM, U738, and Université Paris, France
    Arthritis Rheum 59:25-31. 2008
    ..To assess the impact, in terms of statistical power and bias of treatment effect, of approaches to dealing with missing data in randomized controlled trials of rheumatoid arthritis with radiographic outcomes...
  60. ncbi Violation of the intent-to-treat principle and rate of missing data in superiority trials assessing structural outcomes in rheumatic diseases
    Gabriel Baron
    INSERM U 738, Groupe Hospitalier Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Paris, France
    Arthritis Rheum 52:1858-65. 2005
    ..To evaluate the methodologic quality of and identify methodologic issues in superiority trials assessing structural outcomes in rheumatic diseases...