- Reactive nodular fibrous pseudotumor: a first report of gastric localization and clinicopathologic reviewG Gauchotte
Laboratoire de Pathologie, Hopitaux de Brabois, CHRU, 5 allée du Morvan, Vandoeuvre les Nancy, France
Gastroenterol Clin Biol 33:1076-81. 2009....
- [Metaplastic carcinomas of the breast: a morphological and immunohistochemical study]Guillaume Gauchotte
Laboratoire de Pathologie, Centre Alexis Vautrin, Vandœuvre lès Nancy, France
Ann Pathol 31:18-27. 2011..Metaplastic carcinomas of the breast are rare and form a heterogenic group of tumors, characterized by the presence of squamous or sarcomatoid differentiation...
- [MDCT in the lateral decubitus position with Valsalva maneuver in the evaluation of abdominal wall hernias]G Gauchotte
Service de Radiodiagnostic du Pr Régent, Hopitaux de Brabois, CHU Nancy Hôpital d adulte, rue du Morvan, 54511 Vandoeuvre les Nancy
J Radiol 89:1113-6. 2008..MDCT in the lateral decubitus position during Valsalva is sensitive in the detection of abdominal wall hernias and may increase the hernia size and possibly change its contents...
- BRAF, p53 and SOX2 in anaplastic thyroid carcinoma: evidence for multistep carcinogenesisGuillaume Gauchotte
Department of Pathology, Hopital Central, CHU, Nancy, France
Pathology 43:447-52. 2011..The aim of this study was to genotype a series of papillary thyroid carcinomas (PTCs) and anaplastic thyroid carcinomas (ATCs) for BRAF mutation, and to evaluate p53 and SOX2 expression as factors implicated in tumour progression...
- [Medullomyoblastoma: a medulloblastoma with rhabdomyoblastic differentiation]Guillaume Gauchotte
Laboratoire d anatomie et cytologie pathologiques, Hopital Central, CHU de Nancy, 29, Avenue du Marechal de Lattre de Tassigny, 54000 Nancy, France
Ann Pathol 30:135-8. 2010..The two tumoral populations share the same genetic alterations. The main differential diagnoses are atypical teratoid/rhabdoid tumor, immature teratoma, medulloepithelioma, primitive intracranial rhabdomyosarcoma and myoneurocytoma...
- Methyl(R217)HuR and MCM6 are inversely correlated and are prognostic markers in non small cell lung carcinomaCharlène Vigouroux
Department of Pathology, CHU Nancy, France
Lung Cancer 89:189-96. 2015..Finally, because HuR methylation could be involved in its nucleocytoplasmic shuttling, the expression of methyl(R217)HuR and its relation to cancer survival were determined...
- FVIIIra, CD15, and tryptase performance in the diagnosis of skin stab wound vitality in forensic pathologyGuillaume Gauchotte
Department of Pathology, CHU Nancy, Nancy, France
Int J Legal Med 127:957-65. 2013..Finally, we demonstrated that these markers were not reliable in putrefied or desiccated specimens. In conclusion, CD15 and tryptase, but not FVIIIra, may be useful markers for differentiating recent antemortem from postmortem injuries...
- A combination of smears and cell block preparations provides high diagnostic accuracy for endobronchial ultrasound-guided transbronchial needle aspirationGuillaume Gauchotte
Department of Pathology, CHU Nancy, Nancy, France
Virchows Arch 461:505-12. 2012..42). CBP, as a complement to smears, increases diagnostic yield and sensitivity for both diagnoses of carcinoma and granulomatous inflammation. LBC, if used alone, increases the risk of a false-negative result...
- [Diagnostic accuracy of endobronchial ultrasound-guided transbronchial needle aspiration in mediastinal lymph nodes]Guillaume Gauchotte
Laboratoire de Pathologie, Hopital Central, CHU de Nancy, 29, Avenue du Marechal de Lattre de Tassigny, 54000 Nancy, France
Ann Pathol 31:142-51. 2011..Because it allows collecting only a small amount of materiel, an optimal processing of the samples is needed...
- Methyl donor deficiency affects small-intestinal differentiation and barrier function in ratsAude Bressenot
INSERM U 954, Molecular and Cellular Pathology in Nutrition, Faculte de Medecine, CHU Nancy, Nancy Universite, 9 Avenue de la Forêt de Haye, BP 184, Nancy, 54500 Vandoeuvre, France
Br J Nutr 109:667-77. 2013..15·33%; villus 7 v. 17%). The MDD has dual effects on the small intestine by producing dramatic effects on enterocyte differentiation and barrier function in rats...
- [An isolated vasculitis of uterine cervix and isthmus]E Gauchotte
Service de Gynecologie, Maternite Regionale Universitaire, Hopital Central, CHRU, 10, rue du Docteur Heydenreich, 54000 Nancy, France
J Gynecol Obstet Biol Reprod (Paris) 38:521-3. 2009..At histological examination, necrotizing vasculitis of small and medium-sized arteries was found, suggesting diagnosis of polyarteritis nodosa. There was no argument for systemic vasculitis...
- Skin wounds vitality markers in forensic pathology: An updated reviewJean Matthieu Casse
Department of Pathology, CHU Nancy Inserm U954, Faculty of Medicine, Université de Lorraine, France
Med Sci Law 56:128-37. 2016..Finally, optimal sensitivity and specificity values could probably be reached by combining several markers, validated by large groups of pre- and post-mortem wounds. ..
- In malignant cartilagenous tumors, immunohistochemical expression of procollagen PC1CP peptide is higher and that of PC2CP lower than in benign cartilaginous lesionsCamille Delaunay-Lemarie
Department of Pathology, CHU, Nancy, France
Virchows Arch 467:329-37. 2015..In conclusion, we show that the expression of PC1CP is higher and that of PC2CP lower in malignant cartilaginous tumors. These results support an oncogenic role of PC1CP and anti-oncogenic property of PC2CP in cartilaginous tumors...
- Respiratory epithelial adenomatoid hamartoma of the nose: an updated reviewDuc Trung Nguyen
Department of Ear, Nose, and Throat Head and Neck Surgery, University Hospital of Nancy, University of Lorraine, Nancy, France
Am J Rhinol Allergy 28:187-92. 2014..Data sources included case reports, original articles, and reviews published in English or French in PubMed from 1995 to date...
- Respiratory epithelial adenomatoid hamartoma: a poorly recognized entity with mast cell recruitment and frequently associated with nasal polyposisGuillaume Gauchotte
Departments of Pathology Radiology Centre de Ressources Biologiques Department of Otolaryngology Head and Neck Surgery, CHU INSERM U954, Medical Faculty of Nancy, Université de Lorraine, Nancy, France
Am J Surg Pathol 37:1678-85. 2013..Tryptase-producing MCs, possibly in association with MMP expression, may play a central role in REAH formation...
- Retinoid acid receptor expression is helpful to distinguish between adenoma and well-differentiated carcinoma in the thyroidGuillaume Gauchotte
Department of Pathology, CHU, Nancy, France
Virchows Arch 462:619-32. 2013..Further investigation should be carried out to determine whether the characterization of RR expression might identify patients who could benefit from therapy with RA derivatives...
- Submucosal plexitis as a predictor of postoperative surgical recurrence in Crohn's diseaseAude Bressenot
Inserm U954, Genetic Nutrition and Exposure to Environmental Risks NGERE, Henri Poincare University, Vandoeuvre les Nancy, France
Inflamm Bowel Dis 19:1654-61. 2013..We assessed the value of both submucosal and myenteric plexitis for predicting postoperative surgical recurrence in CD...
- Endothelial Cell Hypertrophy and Microvascular Proliferation in Meningiomas Are Correlated with Higher Histological Grade and Shorter Progression-Free SurvivalCatherine Ling
From the Department of Pathology, CHRU, Nancy, France CL, CP, MT JMC, JMV, GG Department of Neurosurgery, CHRU, Nancy, France FR INSERM U1051, Institut des Neurosciences de Montpellier, Montpellier, France FR INSERM U954, NGERE, Faculte de Medecine de Nancy, Université de Lorraine, Vandoeuvre les Nancy, France RP, JMV, GG Laboratory of Neuropathology, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Paris, France FB, KM INSERM U1127, CNRS UMR 7225, Universite Pierre et Marie Curie Paris 6, institut du cerveau et de la moelle épinière, Paris, France FB, km, MK, MP Centre de Ressources Biologiques, BB 0033 00035, CHRU
J Neuropathol Exp Neurol . 2016..These findings give insight into the use of anti-angiogenic therapies. Further studies are needed to determine whether these markers could allow us to identify patients who could benefit from anti-angiogenic therapies...
- A nonradiated grade II glioma that underwent delayed malignant transformation to a gliosarcoma with meningeal growth and disseminationFabien Rech
Department of Neurosurgery, CHU Nancy, Nancy, France
J Neurol Surg A Cent Eur Neurosurg 75:485-90. 2014..We show a favorable outcome after therapeutic management of this rare entity...
- Predictors of respiratory epithelial adenomatoid hamartomas of the olfactory clefts in patients with nasal polyposisDuc T Nguyen
Department of ENT Head and Neck Surgery, University Hospital of Nancy, Nancy, France Institut National de la Santé et de la Recherche Médicale INSERM CIC EC CIE6, Nancy, France
Laryngoscope 124:2461-5. 2014..To look for predictors of respiratory epithelial adenomatoid hamartomas (REAH) development in patients operated for nasal polyposis (NP) by adjusting on confounding factors...
- [The markers of wound vitality in forensic pathology]Guillaume Gauchotte
Service d Anatomie et Cytologie Pathologiques, Hopital Central, CHU de Nancy, 29, Avenue du Marechal de Lattre de Tassigny, 54000 Nancy, France
Ann Pathol 33:93-101. 2013..g. fibronectin, P-selectin). Finally, optimal sensibility and specificity values would be probably reached by combining several markers, validated with large groups of pre- and post-mortem wounds...
- Expression of minichromosome maintenance MCM6 protein in meningiomas is strongly correlated with histologic grade and clinical outcomeGuillaume Gauchotte
Department of Pathology, Inserm U954, Medical Faculty of Nancy, France
Am J Surg Pathol 36:283-91. 2012..84 (0.73-0.90). In conclusion, because of its strong level of expression and sharp difference in labeling index between indolent and recurrent tumors, MCM6 is the most efficient marker to identify tumors with a high risk of recurrence...
- Salivary gland anlage tumor: a clinicopathological study of two casesGuillaume Gauchotte
Department of Pathology, Central University Hospital CHU Nancy, Nancy, France
Fetal Pediatr Pathol 30:116-23. 2011..Histologically, both lesions were suggestive of SGAT, characterized by epithelial structures that blended with spindle-cells, drawing highly cellular nodules. Connective tissue between nodules contained squamous cystic nests and ducts...