Michel Negrerie

Summary

Affiliation: Ecole Polytechnique
Country: France

Publications

  1. ncbi request reprint Role of heme iron coordination and protein structure in the dynamics and geminate rebinding of nitric oxide to the H93G myoglobin mutant: implications for nitric oxide sensors
    Michel Negrerie
    INSERM U696, Laboratoire d Optique et Biosciences, Ecole Polytechnique, Palaiseau F91120, 91128 Palaiseau Cedex, France
    J Biol Chem 281:10389-98. 2006
  2. ncbi request reprint Functionality of nitrated acetylcholine receptor: the two-step formation of nitrotyrosines reveals their differential role in effectors binding
    Michel Negrerie
    INSERM U696, UMR7645, Laboratoire d Optique et Biosciences, Ecole Polytechnique, Palaiseau, France
    FEBS Lett 579:2643-7. 2005
  3. ncbi request reprint Dynamic regulation of the inducible nitric-oxide synthase by NO: comparison with the endothelial isoform
    Clement Gautier
    Laboratory for Optics and Biosciences, INSERM U451, CNRS Unite Mixte de Recherche 7645, Ecole Polytechnique, 91128 Palaiseau Cedex, France
    J Biol Chem 279:4358-65. 2004
  4. doi request reprint Absorption band III kinetics probe the picosecond heme iron motion triggered by nitric oxide binding to hemoglobin and myoglobin
    Byung Kuk Yoo
    Laboratoire d Optique et Biosciences, INSERM, Ecole Polytechnique, 91128 Palaiseau, France
    J Phys Chem B 116:4106-14. 2012
  5. pmc Quaternary structure controls ligand dynamics in soluble guanylate cyclase
    Byung Kuk Yoo
    Laboratoire d Optique et Biosciences, INSERM U696, CNRS UMR 7645 Ecole Polytechnique, 91128 Palaiseau, France
    J Biol Chem 287:6851-9. 2012
  6. ncbi request reprint Ligand binding dynamics to the heme domain of the oxygen sensor Dos from Escherichia coli
    Ursula Liebl
    Laboratory for Optical Biosciences, INSERM U451, CNRS UMR 7645, Ecole Polytechnique ENSTA, 91128 Palaiseau Cedex, France
    Biochemistry 42:6527-35. 2003
  7. doi request reprint Picosecond binding of the His ligand to four-coordinate heme in cytochrome c': a one-way gate for releasing proximal NO
    Byung Kuk Yoo
    Laboratoire d Optique et Biosciences, INSERM, Ecole Polytechnique, 91128 Palaiseau Cedex, France
    J Am Chem Soc 135:3248-54. 2013
  8. pmc Picosecond primary structural transition of the heme is retarded after nitric oxide binding to heme proteins
    Sergei G Kruglik
    Laboratoire d Optique et Biosciences, Institut National de la Sante et de la Recherche Medicale, Ecole Polytechnique, 91128 Palaiseau, France
    Proc Natl Acad Sci U S A 107:13678-83. 2010
  9. ncbi request reprint Photodissociation of heme distal methionine in ferrous cytochrome C revealed by subpicosecond time-resolved resonance Raman spectroscopy
    Simona Cianetti
    Laboratory for Optics and Biosciences, INSERM U451, CNRS UMR 7645, Ecole Polytechnique, 91128 Palaiseau Cedex, France
    J Am Chem Soc 126:13932-3. 2004
  10. ncbi request reprint Molecular basis for nitric oxide dynamics and affinity with Alcaligenes xylosoxidans cytochrome c
    Sergei G Kruglik
    Ecole Polytechnique, Laboratoire d Optique et Biosciences, CNRS UMR 7645, 91128 Palaiseau Cedex, France
    J Biol Chem 282:5053-62. 2007

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Role of heme iron coordination and protein structure in the dynamics and geminate rebinding of nitric oxide to the H93G myoglobin mutant: implications for nitric oxide sensors
    Michel Negrerie
    INSERM U696, Laboratoire d Optique et Biosciences, Ecole Polytechnique, Palaiseau F91120, 91128 Palaiseau Cedex, France
    J Biol Chem 281:10389-98. 2006
    ..Consequently, the heme coordination state together with the energy barriers provided by the protein structure control the dynamics and affinity for NO-binding enzymes...
  2. ncbi request reprint Functionality of nitrated acetylcholine receptor: the two-step formation of nitrotyrosines reveals their differential role in effectors binding
    Michel Negrerie
    INSERM U696, UMR7645, Laboratoire d Optique et Biosciences, Ecole Polytechnique, Palaiseau, France
    FEBS Lett 579:2643-7. 2005
    ..We concluded that at least two residues involved in agonist binding can be nitrated, which bring similar contributions to the binding energy of the neurotransmitter...
  3. ncbi request reprint Dynamic regulation of the inducible nitric-oxide synthase by NO: comparison with the endothelial isoform
    Clement Gautier
    Laboratory for Optics and Biosciences, INSERM U451, CNRS Unite Mixte de Recherche 7645, Ecole Polytechnique, 91128 Palaiseau Cedex, France
    J Biol Chem 279:4358-65. 2004
    ..Q., Wei, C. C., Ghosh, S., Meade, A. L., Hemann, C., Hille, R., and Stuehr, D. J. (2001) Biochemistry 40, 12819-12825)...
  4. doi request reprint Absorption band III kinetics probe the picosecond heme iron motion triggered by nitric oxide binding to hemoglobin and myoglobin
    Byung Kuk Yoo
    Laboratoire d Optique et Biosciences, INSERM, Ecole Polytechnique, 91128 Palaiseau, France
    J Phys Chem B 116:4106-14. 2012
    ..We concluded that, namely, the band III intensity depends on the heme iron out-of-plane position, as theoretically predicted ( Stavrov , S. S. Biopolymers 2004 , 74 , 37 - 40 )...
  5. pmc Quaternary structure controls ligand dynamics in soluble guanylate cyclase
    Byung Kuk Yoo
    Laboratoire d Optique et Biosciences, INSERM U696, CNRS UMR 7645 Ecole Polytechnique, 91128 Palaiseau, France
    J Biol Chem 287:6851-9. 2012
    ..These strains are likely involved in the transmission of the energy and relaxation toward the activated state after Fe(2+)-His bond breaking. This also reveals the heme domain plasticity modulated by the associated domains and subunit...
  6. ncbi request reprint Ligand binding dynamics to the heme domain of the oxygen sensor Dos from Escherichia coli
    Ursula Liebl
    Laboratory for Optical Biosciences, INSERM U451, CNRS UMR 7645, Ecole Polytechnique ENSTA, 91128 Palaiseau Cedex, France
    Biochemistry 42:6527-35. 2003
    ..Further remarkable observations include evidence for stable (>4 ns) photooxidation of six-coordinate ferrous heme, with a quantum yield of 4-8%...
  7. doi request reprint Picosecond binding of the His ligand to four-coordinate heme in cytochrome c': a one-way gate for releasing proximal NO
    Byung Kuk Yoo
    Laboratoire d Optique et Biosciences, INSERM, Ecole Polytechnique, 91128 Palaiseau Cedex, France
    J Am Chem Soc 135:3248-54. 2013
    ....
  8. pmc Picosecond primary structural transition of the heme is retarded after nitric oxide binding to heme proteins
    Sergei G Kruglik
    Laboratoire d Optique et Biosciences, Institut National de la Sante et de la Recherche Medicale, Ecole Polytechnique, 91128 Palaiseau, France
    Proc Natl Acad Sci U S A 107:13678-83. 2010
    ..This observed phenomenon constitutes the primary structural transition in heme proteins induced by NO binding...
  9. ncbi request reprint Photodissociation of heme distal methionine in ferrous cytochrome C revealed by subpicosecond time-resolved resonance Raman spectroscopy
    Simona Cianetti
    Laboratory for Optics and Biosciences, INSERM U451, CNRS UMR 7645, Ecole Polytechnique, 91128 Palaiseau Cedex, France
    J Am Chem Soc 126:13932-3. 2004
    ....
  10. ncbi request reprint Molecular basis for nitric oxide dynamics and affinity with Alcaligenes xylosoxidans cytochrome c
    Sergei G Kruglik
    Ecole Polytechnique, Laboratoire d Optique et Biosciences, CNRS UMR 7645, 91128 Palaiseau Cedex, France
    J Biol Chem 282:5053-62. 2007
    ..These dynamic properties allow the trapping of NO within the protein core and represent an extreme behavior observed among heme proteins...
  11. ncbi request reprint Nitric oxide (NO) traffic in endothelial NO synthase. Evidence for a new NO binding site dependent on tetrahydrobiopterin?
    Anny Slama-Schwok
    Laboratory for Optics and Biosciences, INSERM U451, CNRS Unite Mixte de Recherche 7645, Ecole Polytechnique, 91128 Palaiseau, France
    J Biol Chem 277:7581-6. 2002
    ..The new non-heme site may act as a "doorstep" to the heme pocket and control NO escape from eNOS...
  12. doi request reprint Picosecond to second dynamics reveals a structural transition in Clostridium botulinum NO-sensor triggered by the activator BAY-41-2272
    Byung Kuk Yoo
    Laboratoire d Optique et Biosciences, INSERM U696, CNRS UMR 7645, Ecole Polytechnique, 91128 Palaiseau Cedex, France
    ACS Chem Biol 7:2046-54. 2012
    ..This result demonstrates that the BAY 41-2272 binding site resides in the β(1)(200) sGC heme domain and is the same in sGC and in the NO-sensor from Clostridium botulinum...
  13. ncbi request reprint Ultrafast heme dynamics in ferrous versus ferric cytochrome c studied by time-resolved resonance Raman and transient absorption spectroscopy
    Michel Negrerie
    Laboratory for Optics and Biosciences, CNRS UMR 7645, Ecole Polytechnique, 91128 Palaiseau Cedex, France
    J Phys Chem B 110:12766-81. 2006
    ....
  14. pmc Motion of proximal histidine and structural allosteric transition in soluble guanylate cyclase
    Byung Kuk Yoo
    Laboratoire d Optique et Biosciences, INSERM U1182, Ecole Polytechnique, 91128 Palaiseau Cedex, France and
    Proc Natl Acad Sci U S A 112:E1697-704. 2015
    ..We show here that this structural allosteric transition takes place in the range 1-50 μs. In this context, the detection of NO binding to the proximal side of sGC heme is discussed. ..
  15. pmc Ultrafast ligand rebinding in the heme domain of the oxygen sensors FixL and Dos: general regulatory implications for heme-based sensors
    Ursula Liebl
    Laboratory for Optical Biosciences, Institut National de la Santé et de la Recherche Médicale U451, Centre National de la Recherche Scientifique Unité Mixte de Recherche 7645, France
    Proc Natl Acad Sci U S A 99:12771-6. 2002
    ..The general implications for the functioning of heme-based ligand sensors are discussed in the light of recent studies on heme-based NO and CO sensors...