Sophie Desplat-Jego

Summary

Country: France

Publications

  1. doi request reprint BioPlex 2200 multiplexed system: simultaneous detection of anti-dsDNA and anti-chromatin antibodies in patients with systemic lupus erythematosus
    Nathalie Bardin
    Laboratoire d Immunologie, Hopital de Conception, Marseille, France
    Autoimmunity 42:63-8. 2009
  2. pmc Update on Anti-Saccharomyces cerevisiae antibodies, anti-nuclear associated anti-neutrophil antibodies and antibodies to exocrine pancreas detected by indirect immunofluorescence as biomarkers in chronic inflammatory bowel diseases: results of a multicent
    S Desplat-Jego
    Laboratoire d Immunologie, CHU de la Conception, 147, Bd Baille, Marseille 13005, France
    World J Gastroenterol 13:2312-8. 2007
  3. ncbi request reprint Evaluation of the BioPlex 2200 ANA screen for the detection of antinuclear antibodies and comparison with conventional methods
    Sophie Desplat-Jego
    Laboratoire d Immunologie, Hopital de la Conception, Marseille, France
    Ann N Y Acad Sci 1109:245-55. 2007
  4. doi request reprint TWEAK is expressed at the cell surface of monocytes during multiple sclerosis
    Sophie Desplat-Jego
    Neurobioligie des Interactions Cellulaires et Neurophysiopathologie, CNRS UMR 6184, IFR Jean Roche, 51 Bd Pierre Dramard, 13 916 Marseille cedex 20, France
    J Leukoc Biol 85:132-5. 2009
  5. ncbi request reprint Anti-TWEAK monoclonal antibodies reduce immune cell infiltration in the central nervous system and severity of experimental autoimmune encephalomyelitis
    Sophie Desplat-Jego
    Universite de la Mediterranee, NICN, CNRS UMR 6184, IFR Jean Roche, Marseille, France
    Clin Immunol 117:15-23. 2005
  6. ncbi request reprint Quantification of immunoglobulin free light chains in cerebrospinal fluid by nephelometry
    Sophie Desplat-Jego
    Laboratoire d Immunologie, Hopital de la Conception, 147, Bd Baille, 13005 Marseille UMR 6184, Faculte de Medecine Timone, 27, Bd Jean Moulin, 13005 Marseille, France
    J Clin Immunol 25:338-45. 2005
  7. ncbi request reprint TWEAK is expressed by glial cells, induces astrocyte proliferation and increases EAE severity
    Sophie Desplat-Jego
    NICN CNRS FRE 2533, IFR Jean Roche, Universite de la Mediterranee, 13 916 Cedex 20, Marseilles, France
    J Neuroimmunol 133:116-23. 2002
  8. pmc TWEAK-binding autoantibodies are generated during psoriatic arthritis and are not influenced by anti-TNF therapy
    Sandrine Guis
    Department of Rheumatology 1, CHU Sainte Marguerite, 270, Bld de Sainte Marguerite, 13009, Marseille, France
    J Transl Med 14:185. 2016
  9. pmc TWEAK/Fn14 pathway modulates properties of a human microvascular endothelial cell model of blood brain barrier
    Delphine Stephan
    Aix Marseille Universite, NICN, Marseille, France
    J Neuroinflammation 10:9. 2013
  10. doi request reprint Anti-mitochondrial-2 antibodies (anti-PDC-E2): a marker for autoimmune hepatitis of children?
    Romain Bailloud
    Laboratoire d Immunologie, pole de biologie, Hopital de Conception, 147, boulevard Baille, Marseille, France
    Clin Res Hepatol Gastroenterol 36:e57-9. 2012

Collaborators

Detail Information

Publications13

  1. doi request reprint BioPlex 2200 multiplexed system: simultaneous detection of anti-dsDNA and anti-chromatin antibodies in patients with systemic lupus erythematosus
    Nathalie Bardin
    Laboratoire d Immunologie, Hopital de Conception, Marseille, France
    Autoimmunity 42:63-8. 2009
    ..Antibodies for double-stranded DNA (anti-dsDNA) and chromatin represent specific markers of systemic lupus erythematosus (SLE)...
  2. pmc Update on Anti-Saccharomyces cerevisiae antibodies, anti-nuclear associated anti-neutrophil antibodies and antibodies to exocrine pancreas detected by indirect immunofluorescence as biomarkers in chronic inflammatory bowel diseases: results of a multicent
    S Desplat-Jego
    Laboratoire d Immunologie, CHU de la Conception, 147, Bd Baille, Marseille 13005, France
    World J Gastroenterol 13:2312-8. 2007
    ..Performing a multicenter study we primarily aimed to determine the performance of ASCA, NANA and PAB tests for IBD diagnosis in children and adults, and secondarily to evaluate the prevalence of these markers in CoD...
  3. ncbi request reprint Evaluation of the BioPlex 2200 ANA screen for the detection of antinuclear antibodies and comparison with conventional methods
    Sophie Desplat-Jego
    Laboratoire d Immunologie, Hopital de la Conception, Marseille, France
    Ann N Y Acad Sci 1109:245-55. 2007
    ..The capability of this multiplexed technology to analyze simultaneously 13 ANA autoantibodies leads to the rapid availability of an "autoimmune connective tissue disease serologic profile."..
  4. doi request reprint TWEAK is expressed at the cell surface of monocytes during multiple sclerosis
    Sophie Desplat-Jego
    Neurobioligie des Interactions Cellulaires et Neurophysiopathologie, CNRS UMR 6184, IFR Jean Roche, 51 Bd Pierre Dramard, 13 916 Marseille cedex 20, France
    J Leukoc Biol 85:132-5. 2009
    ..We demonstrated for the first time that TWEAK is expressed at the cell surface of monocytes during MS, especially in the CISSMS group. Our results support the proposal that TWEAK could be a target for antibody therapy in MS...
  5. ncbi request reprint Anti-TWEAK monoclonal antibodies reduce immune cell infiltration in the central nervous system and severity of experimental autoimmune encephalomyelitis
    Sophie Desplat-Jego
    Universite de la Mediterranee, NICN, CNRS UMR 6184, IFR Jean Roche, Marseille, France
    Clin Immunol 117:15-23. 2005
    ..We observed a reduction of disease severity and leukocyte infiltration when mice were treated after the priming phase...
  6. ncbi request reprint Quantification of immunoglobulin free light chains in cerebrospinal fluid by nephelometry
    Sophie Desplat-Jego
    Laboratoire d Immunologie, Hopital de la Conception, 147, Bd Baille, 13005 Marseille UMR 6184, Faculte de Medecine Timone, 27, Bd Jean Moulin, 13005 Marseille, France
    J Clin Immunol 25:338-45. 2005
    ..In conclusion, FLC kappa index should be considered as a useful complementary test for MS diagnosis. Its pronostic interest remains to be determined on a larger cohort of possible MS patients...
  7. ncbi request reprint TWEAK is expressed by glial cells, induces astrocyte proliferation and increases EAE severity
    Sophie Desplat-Jego
    NICN CNRS FRE 2533, IFR Jean Roche, Universite de la Mediterranee, 13 916 Cedex 20, Marseilles, France
    J Neuroimmunol 133:116-23. 2002
    ..Finally, EAE severity is enhanced in soluble TWEAK-overexpressing transgenic mice. These results support the contention that TWEAK is involved in CNS inflammation...
  8. pmc TWEAK-binding autoantibodies are generated during psoriatic arthritis and are not influenced by anti-TNF therapy
    Sandrine Guis
    Department of Rheumatology 1, CHU Sainte Marguerite, 270, Bld de Sainte Marguerite, 13009, Marseille, France
    J Transl Med 14:185. 2016
    ..However, the role of TNF-alpha in the regulation of TWEAK modulation of inflammation during PsoA remains unknown...
  9. pmc TWEAK/Fn14 pathway modulates properties of a human microvascular endothelial cell model of blood brain barrier
    Delphine Stephan
    Aix Marseille Universite, NICN, Marseille, France
    J Neuroinflammation 10:9. 2013
    ..Nevertheless, the mechanisms involved in such conditions are complex and remain to be explored, especially because there is a lack of data concerning the TWEAK/Fn14 pathway in microvascular cerebral endothelial cells...
  10. doi request reprint Anti-mitochondrial-2 antibodies (anti-PDC-E2): a marker for autoimmune hepatitis of children?
    Romain Bailloud
    Laboratoire d Immunologie, pole de biologie, Hopital de Conception, 147, boulevard Baille, Marseille, France
    Clin Res Hepatol Gastroenterol 36:e57-9. 2012
    ..We described here the second case in the literature of paediatric autoimmune hepatitis associated with well documented AMA-2...
  11. doi request reprint Diagnostic performance of a new vimentin-derived ACPA (CCP high sensitive) in patients with rheumatoid arthritis
    Daniel Bertin
    Service d Immunologie, pole de biologie, Hopital de la Conception, Assistance Publique Hopitaux de Marseille, 147, Bd Baille, 13005, Marseille, France
    Immunol Res 64:455-60. 2016
    ..There was a moderate correlation between CCP hs and CCP3 titers (Pearson's r = 0.43; p < 0.0001). These results support the contention that anti-CCP hs antibodies are new reliable ACPA with high specificity for RA...
  12. pmc Targeting tissular immune response improves diagnostic performance of anti-Saccharomyces cerevisiae antibodies (ASCA) in Crohn's disease
    Daniel Bertin
    Service d Immunologie, pole de biologie, Hopital de la Conception, Assistance Publique Hopitaux de Marseille, Marseille, France Aix Marseille Université, Centre National de la Recherche Scientifique, Neurobiologie des Interactions Cellulaires et Neurophysiopathologie UMR 7259, Marseille, France
    PLoS ONE 8:e80433. 2013
    ..This assaying approach in CD diagnosis should be taken into consideration in the future especially in CD forms with isolated colonic involvement. ..