Benjamin Descours

Summary

Country: France

Publications

  1. pmc SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells
    Benjamin Descours
    Institut de Genetique Humaine, CNRS UPR1142, Laboratoires de Virologie Moléculaire, Montpellier, France
    Retrovirology 9:87. 2012
  2. doi request reprint Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1
    Alexandra Cribier
    Institut de Genetique Humaine, CNRS UPR1142, Laboratoires de Virologie Moléculaire, Montpellier 34000, France
    Cell Rep 3:1036-43. 2013
  3. doi request reprint CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses
    Benjamin Descours
    Institut de G n tique Humaine, Laboratoire de Virologie Mol culaire, UMR9002, CNRS, Universit de Montpellier, Montpellier, France
    Nature 543:564-567. 2017

Detail Information

Publications3

  1. pmc SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells
    Benjamin Descours
    Institut de Genetique Humaine, CNRS UPR1142, Laboratoires de Virologie Moléculaire, Montpellier, France
    Retrovirology 9:87. 2012
    ..Quiescent CD4+ T lymphocytes are highly refractory to HIV-1 infection due to a block at reverse transcription...
  2. doi request reprint Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1
    Alexandra Cribier
    Institut de Genetique Humaine, CNRS UPR1142, Laboratoires de Virologie Moléculaire, Montpellier 34000, France
    Cell Rep 3:1036-43. 2013
    ..Our results uncover the phosphorylation of SAMHD1 at Thr592 by cyclin A2/CDK1 as a key regulatory mechanism of its antiviral activity...
  3. doi request reprint CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses
    Benjamin Descours
    Institut de G n tique Humaine, Laboratoire de Virologie Mol culaire, UMR9002, CNRS, Universit de Montpellier, Montpellier, France
    Nature 543:564-567. 2017
    ..Our discovery that CD32a(+) lymphocytes represent the elusive HIV-1 reservoir may lead to insights that will facilitate the specific targeting and elimination of this reservoir...