Jacques Delforge

Summary

Country: France

Publications

  1. ncbi request reprint In vivo quantification and parametric images of the cardiac beta-adrenergic receptor density
    Jacques Delforge
    Service Hospitalier Frederic Joliot, Commissariat à l Energie Atomique Direction des Sciences du Vivant, Orsay, France
    J Nucl Med 43:215-26. 2002
  2. pmc In vivo quantification of monoamine oxidase A in baboon brain: a PET study using [(11)C]befloxatone and the multi-injection approach
    Michel Bottlaender
    CEA, DSV, I2BM, Service Hospitalier Frederic Joliot, 4, place du General Leclerc, F 91401 Orsay, France
    J Cereb Blood Flow Metab 30:792-800. 2010
  3. ncbi request reprint Quantification of cerebral nicotinic acetylcholine receptors by PET using 2-[18F]fluoro-A-85380 and the multiinjection approach
    Jean Dominique Gallezot
    Service Hospitalier Frederic Joliot, I2BM, DSV, CEA, Orsay, France
    J Cereb Blood Flow Metab 28:172-89. 2008
  4. ncbi request reprint Modeling [18 F]MPPF positron emission tomography kinetics for the determination of 5-hydroxytryptamine(1A) receptor concentration with multiinjection
    Nicolas Costes
    Centre d Exploration et de Recherche Médicales par Emission de Positons, Lyon, France
    J Cereb Blood Flow Metab 22:753-65. 2002
  5. ncbi request reprint Seizure-related short-term plasticity of benzodiazepine receptors in partial epilepsy: a [11C]flumazenil-PET study
    Sandrine Bouvard
    EA1880, Federal Institute of Neurosciences, Neurological Hospital, Lyon, France
    Brain 128:1330-43. 2005
  6. ncbi request reprint Consensus nomenclature for in vivo imaging of reversibly binding radioligands
    Robert B Innis
    National Institute of Mental Health, Molecular Imaging Branch, Bethesda, Maryland, USA
    J Cereb Blood Flow Metab 27:1533-9. 2007

Collaborators

Detail Information

Publications6

  1. ncbi request reprint In vivo quantification and parametric images of the cardiac beta-adrenergic receptor density
    Jacques Delforge
    Service Hospitalier Frederic Joliot, Commissariat à l Energie Atomique Direction des Sciences du Vivant, Orsay, France
    J Nucl Med 43:215-26. 2002
    ..The purpose of this study was to improve and confirm the validity of this approach through a better knowledge of the associated ligand-receptor model, estimated for the first time using the multiinjection approach...
  2. pmc In vivo quantification of monoamine oxidase A in baboon brain: a PET study using [(11)C]befloxatone and the multi-injection approach
    Michel Bottlaender
    CEA, DSV, I2BM, Service Hospitalier Frederic Joliot, 4, place du General Leclerc, F 91401 Orsay, France
    J Cereb Blood Flow Metab 30:792-800. 2010
    ..The cerebellum presented the lowest binding site density (66+/-13 pmol/mL). Apparent affinity was found to be similar in all structures (K(d)V(R)=6.4+/-1.5 nmol/L). This study is the first PET-based estimation of the B(max) of an enzyme...
  3. ncbi request reprint Quantification of cerebral nicotinic acetylcholine receptors by PET using 2-[18F]fluoro-A-85380 and the multiinjection approach
    Jean Dominique Gallezot
    Service Hospitalier Frederic Joliot, I2BM, DSV, CEA, Orsay, France
    J Cereb Blood Flow Metab 28:172-89. 2008
    ..The ratio of radioligand concentration in these two compartments then overestimates the true equilibrium value, an unfavorable situation to estimate distribution volumes from late images after a bolus injection...
  4. ncbi request reprint Modeling [18 F]MPPF positron emission tomography kinetics for the determination of 5-hydroxytryptamine(1A) receptor concentration with multiinjection
    Nicolas Costes
    Centre d Exploration et de Recherche Médicales par Emission de Positons, Lyon, France
    J Cereb Blood Flow Metab 22:753-65. 2002
    ..This study confirms the value of MPPF in the investigation of normal and pathologic systems involving the limbic network and 5-HT1A receptors. Standard values can be used for the simulation of simplified protocols...
  5. ncbi request reprint Seizure-related short-term plasticity of benzodiazepine receptors in partial epilepsy: a [11C]flumazenil-PET study
    Sandrine Bouvard
    EA1880, Federal Institute of Neurosciences, Neurological Hospital, Lyon, France
    Brain 128:1330-43. 2005
    ....
  6. ncbi request reprint Consensus nomenclature for in vivo imaging of reversibly binding radioligands
    Robert B Innis
    National Institute of Mental Health, Molecular Imaging Branch, Bethesda, Maryland, USA
    J Cereb Blood Flow Metab 27:1533-9. 2007
    ..An international group of experts in pharmacokinetic modeling recommends a consensus nomenclature to describe in vivo molecular imaging of reversibly binding radioligands...