Yves Colin

Summary

Country: France

Publications

  1. ncbi request reprint Rh proteins: a family of structural membrane proteins with putative transport activity
    Yves Colin
    Inserm U76 Institut National de la Transfusion Sanguine, Paris, France
    Vox Sang 83:179-83. 2002
  2. ncbi request reprint Increased adhesion to endothelial cells of erythrocytes from patients with polycythemia vera is mediated by laminin alpha5 chain and Lu/BCAM
    Marie Paule Wautier
    INSERM U665, Paris, France
    Blood 110:894-901. 2007
  3. ncbi request reprint Protein kinase A-dependent phosphorylation of Lutheran/basal cell adhesion molecule glycoprotein regulates cell adhesion to laminin alpha5
    Emilie Gauthier
    INSERM U665, Paris, F 75015, France
    J Biol Chem 280:30055-62. 2005
  4. doi request reprint Generation and characterisation of Rhd and Rhag null mice
    Dominique Goossens
    Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, Paris, France
    Br J Haematol 148:161-72. 2010
  5. ncbi request reprint Genetic inactivation of the laminin alpha5 chain receptor Lu/BCAM leads to kidney and intestinal abnormalities in the mouse
    Cécile Rahuel
    Institut National de la Sante et de la Recherche Medicale, Unité 665, Institut National de la Transfusion Sanguine, Paris, France
    Am J Physiol Renal Physiol 294:F393-406. 2008
  6. doi request reprint Human RhAG ammonia channel is impaired by the Phe65Ser mutation in overhydrated stomatocytic red cells
    Sandrine Genetet
    INSERM U, Paris, France
    Am J Physiol Cell Physiol 302:C419-28. 2012
  7. doi request reprint Decreased sickle red blood cell adhesion to laminin by hydroxyurea is associated with inhibition of Lu/BCAM protein phosphorylation
    Pablo Bartolucci
    INSERM, Unité Mixte de Recherche en Santé 665, Paris, France
    Blood 116:2152-9. 2010
  8. ncbi request reprint Endothelial Lu/BCAM glycoproteins are novel ligands for red blood cell alpha4beta1 integrin: role in adhesion of sickle red blood cells to endothelial cells
    Wassim El Nemer
    INSERM Unité 665, Paris, France
    Blood 109:3544-51. 2007
  9. pmc Human Rhesus B and Rhesus C glycoproteins: properties of facilitated ammonium transport in recombinant kidney cells
    Nedjma Zidi-Yahiaoui
    INSERM, U665, Paris, F 75015, France
    Biochem J 391:33-40. 2005
  10. pmc Functional reconstitution into liposomes of purified human RhCG ammonia channel
    Isabelle Mouro-Chanteloup
    Inserm UMR_S 665, Paris, France
    PLoS ONE 5:e8921. 2010

Collaborators

Detail Information

Publications38

  1. ncbi request reprint Rh proteins: a family of structural membrane proteins with putative transport activity
    Yves Colin
    Inserm U76 Institut National de la Transfusion Sanguine, Paris, France
    Vox Sang 83:179-83. 2002
  2. ncbi request reprint Increased adhesion to endothelial cells of erythrocytes from patients with polycythemia vera is mediated by laminin alpha5 chain and Lu/BCAM
    Marie Paule Wautier
    INSERM U665, Paris, France
    Blood 110:894-901. 2007
    ..Phosphorylation of Lu/BCAM increases RBC adhesion. Our results indicate that JAK2 mutation might be linked to Lu/BCAM modification and increased RBC adhesiveness, which may be a factor favoring thrombosis in PV...
  3. ncbi request reprint Protein kinase A-dependent phosphorylation of Lutheran/basal cell adhesion molecule glycoprotein regulates cell adhesion to laminin alpha5
    Emilie Gauthier
    INSERM U665, Paris, F 75015, France
    J Biol Chem 280:30055-62. 2005
    ..It is postulated that modulation of the phosphorylation state of Lu gp might be a critical factor for the sickle red cells adhesiveness to laminin alpha5 in sickle cell disease...
  4. doi request reprint Generation and characterisation of Rhd and Rhag null mice
    Dominique Goossens
    Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, Paris, France
    Br J Haematol 148:161-72. 2010
    ..These knockout mice should prove useful for further dissecting the physiological roles of Rh and Rhag proteins in the red cell membrane...
  5. ncbi request reprint Genetic inactivation of the laminin alpha5 chain receptor Lu/BCAM leads to kidney and intestinal abnormalities in the mouse
    Cécile Rahuel
    Institut National de la Sante et de la Recherche Medicale, Unité 665, Institut National de la Transfusion Sanguine, Paris, France
    Am J Physiol Renal Physiol 294:F393-406. 2008
    ....
  6. doi request reprint Human RhAG ammonia channel is impaired by the Phe65Ser mutation in overhydrated stomatocytic red cells
    Sandrine Genetet
    INSERM U, Paris, France
    Am J Physiol Cell Physiol 302:C419-28. 2012
    ....
  7. doi request reprint Decreased sickle red blood cell adhesion to laminin by hydroxyurea is associated with inhibition of Lu/BCAM protein phosphorylation
    Pablo Bartolucci
    INSERM, Unité Mixte de Recherche en Santé 665, Paris, France
    Blood 116:2152-9. 2010
    ..We provide evidence that hydroxyurea could reduce abnormal sickle red blood cell adhesion to the vascular wall by regulating the activation state of adhesion molecules independently of their expression level...
  8. ncbi request reprint Endothelial Lu/BCAM glycoproteins are novel ligands for red blood cell alpha4beta1 integrin: role in adhesion of sickle red blood cells to endothelial cells
    Wassim El Nemer
    INSERM Unité 665, Paris, France
    Blood 109:3544-51. 2007
    ..This novel interaction between integrin alpha(4)beta(1) in sickle red cells and endothelial Lu/BCAM proteins could participate in sickle cell adhesion to endothelium and potentially play a role in vaso-occlusive episodes...
  9. pmc Human Rhesus B and Rhesus C glycoproteins: properties of facilitated ammonium transport in recombinant kidney cells
    Nedjma Zidi-Yahiaoui
    INSERM, U665, Paris, F 75015, France
    Biochem J 391:33-40. 2005
    ..Natl. Acad. Sci. U.S.A. 101, 17222-17227] constitute a family of NH3 channels in mammalian cells...
  10. pmc Functional reconstitution into liposomes of purified human RhCG ammonia channel
    Isabelle Mouro-Chanteloup
    Inserm UMR_S 665, Paris, France
    PLoS ONE 5:e8921. 2010
    ..To demonstrate that Rh glycoproteins by themselves transport NH(3), human RhCG was purified to homogeneity and reconstituted into liposomes, giving new insights into its channel functional properties...
  11. doi request reprint JAK2V617F activates Lu/BCAM-mediated red cell adhesion in polycythemia vera through an EpoR-independent Rap1/Akt pathway
    Maria De Grandis
    INSERM U665, Paris, France
    Blood 121:658-65. 2013
    ..This new characteristic of JAK2V617F could play a critical role in initiating abnormal interactions among circulating and endothelial cells in patients with PV...
  12. ncbi request reprint Sequence, evolution and ligand binding properties of mammalian Duffy antigen/receptor for chemokines
    Christophe Tournamille
    INSERM U76, Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, 75015, Paris, France
    Immunogenetics 55:682-94. 2004
    ..Analysis of the deduced amino acid sequences highlighted the conservation of some amino acid residues, which should prove to be critical for the structural and functional properties of DARC...
  13. doi request reprint Rapid Cl⁻/HCO⁻₃exchange kinetics of AE1 in HEK293 cells and hereditary stomatocytosis red blood cells
    Etienne Frumence
    INSERM U665, Paris, France
    Am J Physiol Cell Physiol 305:C654-62. 2013
    ..This technical approach thus provides significant improvements in anion exchange analysis in red blood cells. ..
  14. doi request reprint Novel role for the Lu/BCAM-spectrin interaction in actin cytoskeleton reorganization
    Emmanuel Collec
    INSERM, UMR S 665, Paris, F 00 75015, France
    Biochem J 436:699-708. 2011
    ....
  15. doi request reprint Functional analysis of human RhCG: comparison with E. coli ammonium transporter reveals similarities in the pore and differences in the vestibule
    Nedjma Zidi-Yahiaoui
    Institut National de la Sante et de la Recherche Medicale, UMR S665, Paris, France
    Am J Physiol Cell Physiol 297:C537-47. 2009
    ..The impact of the mutations suggests that, although having a common function and a similar channel structure, bacterial AmtB and human Rh vary in several aspects of the NH(3) transport mechanisms...
  16. ncbi request reprint Genetic ablation of Rhbg in the mouse does not impair renal ammonium excretion
    Regine Chambrey
    INSERM U652, IFR58, Institut des Cordeliers, Paris, France
    Am J Physiol Renal Physiol 289:F1281-90. 2005
    ..We conclude that Rhbg is not a critical determinant of NH(4)(+) excretion by the kidney and of NH(4)(+) detoxification by the liver in vivo...
  17. ncbi request reprint Rh proteins: key structural and functional components of the red cell membrane
    Caroline Le Van Kim
    Inserm U76 Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, 75015 Paris, France
    Blood Rev 20:93-110. 2006
    ..In RBCs, RhAG may transport NH(3) to detoxifying organs like kidney and liver and with non-erythroid tissues orthologs may contribute to regulation of the acid-base balance...
  18. pmc Evidence of a structural and functional ammonium transporter RhBG·anion exchanger 1·ankyrin-G complex in kidney epithelial cells
    Sandrine Genetet
    From INSERM U1134, 75739 Paris, France, the Université Paris Diderot, Sorbonne Paris Cité, UMR_S1134, 75739 Paris, France, the Institut National de la Transfusion Sanguine, 75739 Paris, France, and the Laboratoire d Excellence GR Ex, 75238 Paris, France
    J Biol Chem 290:6925-36. 2015
    ..This renal complex could participate in the regulation of acid-base homeostasis. ..
  19. doi request reprint Abnormal properties of red blood cells suggest a role in the pathophysiology of Gaucher disease
    Mélanie Franco
    INSERM U665, INTS, 6 rue Alexandre Cabanel, Paris, France
    Blood 121:546-55. 2013
    ..The demonstration that GD RBCs have abnormal rheologic and adhesion properties suggests that they may trigger ischemic events in GD, and possibly phagocytosis by macrophages, leading to the appearance of pathogenic Gaucher cells...
  20. ncbi request reprint A mutant alphaII-spectrin designed to resist calpain and caspase cleavage questions the functional importance of this process in vivo
    Fleur Meary
    INSERM, U665, Paris, France
    J Biol Chem 282:14226-37. 2007
    ..Our finding also argues against a critical role of this particular alphaII-spectrin cleavage in either major cellular functions or in normal development...
  21. ncbi request reprint Direct interaction between the Lu/B-CAM adhesion glycoproteins and erythroid spectrin
    Yolande Kroviarski
    INSERM U76, Institut National de la Transfusion Sanguine, Paris, France
    Br J Haematol 126:255-64. 2004
    ..Since Lu gps are low abundant proteins, we speculate that their interaction with spectrin might be critical for signalling and receptor function rather than for participating in the linkage of the lipid bilayer to the red cell skeleton...
  22. pmc Lutheran/basal cell adhesion molecule accelerates progression of crescentic glomerulonephritis in mice
    Jin Huang
    1 Paris Cardiovascular Research Centre, Institut National de la Sante et de la Recherche Medicale INSERM, Paris, France 2 Université Paris Descartes, Sorbonne Paris Cité, Paris, France
    Kidney Int 85:1123-36. 2014
    ..Thus, Lu/BCAM may have a critical role in facilitating the accumulation of monocytes and macrophages, thereby exacerbating renal injury. ..
  23. doi request reprint AlphaII-spectrin is critical for cell adhesion and cell cycle
    Sylvain Metral
    INSERM, U665, Paris, F 75015, France
    J Biol Chem 284:2409-18. 2009
    ..Our results provide novel insights into spectrin functions by demonstrating the involvement of alphaII-spectrin in cell cycle regulation and actin organization...
  24. ncbi request reprint Structure-function analysis of the extracellular domains of the Duffy antigen/receptor for chemokines: characterization of antibody and chemokine binding sites
    Christophe Tournamille
    INSERM U76, Institut National de la Transfusion Sanguine, Paris, France
    Br J Haematol 122:1014-23. 2003
    ..We also showed that N-glycosylation of DARC occurred on N16SS and did not influence antibody and chemokine binding...
  25. ncbi request reprint Large-scale pre-diagnosis study of fetal RHD genotyping by PCR on plasma DNA from RhD-negative pregnant women
    Christelle Rouillac-Le Sciellour
    Perinatal Hemobiology National Reference Centre CNRHP, Hopital Saint Antoine, Paris, France
    Mol Diagn 8:23-31. 2004
    ..The fetal DNA present in maternal plasma offers an opportunity for risk-free prenatal diagnosis...
  26. ncbi request reprint Evidence that the red cell skeleton protein 4.2 interacts with the Rh membrane complex member CD47
    Isabelle Mouro-Chanteloup
    Institut National de la Santé et de la Recherche Médicale INSERM U76, Institut National de la Transfusion Sanguine, Paris, France
    Blood 101:338-44. 2003
    ..2(-) and Rh(null) red cells...
  27. ncbi request reprint RhBG and RhCG, the putative ammonia transporters, are expressed in the same cells in the distal nephron
    Fabienne Quentin
    Institut National de la Santé et de la Recherche Médicale Unité 356, Institut Fédératif de Recherche 58, Universite Pierre et Marie Curie, Paris, France
    J Am Soc Nephrol 14:545-54. 2003
    ..In conclusion, RhBG and RhCG are present in a major site of ammonia secretion in the kidney, i.e., the CNT and CD, in agreement with their putative role in ammonium transport...
  28. pmc The human Kell blood group binds the erythroid 4.1R protein: new insights into the 4.1R-dependent red cell membrane complex
    Slim Azouzi
    Institut National de la Transfusion Sanguine, Paris, France
    Br J Haematol 171:862-71. 2015
    ..1. These findings provide novel insights into the structural organization of blood group antigen proteins into the 4.1R complex of the human red cell membrane. ..
  29. pmc Erythroid Adhesion Molecules in Sickle Cell Anaemia Infants: Insights Into Early Pathophysiology
    Valentine Brousse
    Reference Centre for Sickle Cell Disease, Pediatric Department, Hôpital Universitaire Necker Enfants Malades, APHP, Paris, France Université Paris Descartes, Paris, France INSERM, U1134, F 75739 Paris, France Université Paris Diderot, Sorbonne Paris Cité, UMR_S 1134, F 75739 Paris, France Institut National de la Transfusion Sanguine, F 75739 Paris, France Laboratoire d Excellence GR Ex, France
    EBioMedicine 2:154-7. 2015
    ....
  30. doi request reprint Red cell adhesion in human diseases
    Yves Colin
    aInserm U1134 bUniversité Paris Diderot, Sorbonne Paris Cité, UMR_S 1134 cInstitut National de la Transfusion Sanguine dLaboratoire d Excellence GR Ex, Paris, France
    Curr Opin Hematol 21:186-92. 2014
    ..These pathologies share common clinical manifestations, that is vaso-occlusion and/or thrombotic events...
  31. pmc Serotonin is a key factor for mouse red blood cell survival
    Pascal Amireault
    Faculte de Medecine, Université Paris Descartes Sorbonne Paris Cité, Institut Imagine, CNRS UMR 8147, Hôpital Universitaire Necker Enfants Malades, Paris, France Laboratoire d Excellence GR Ex, Paris, France Inserm UMR_S665, Institut National de la Transfusion Sanguine, Paris, France
    PLoS ONE 8:e83010. 2013
    ..We further demonstrate a link between oxidation and the removal of damaged RBC following transfusion, as supplementation with 5-HT improves RBC post-transfusion survival in a mouse model of blood banking. ..
  32. ncbi request reprint Rh-RhAG/ankyrin-R, a new interaction site between the membrane bilayer and the red cell skeleton, is impaired by Rh(null)-associated mutation
    Virginie Nicolas
    INSERM U76, Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, 75015 Paris, France
    J Biol Chem 278:25526-33. 2003
    ..These results identify the Rh/RhAG-ankyrin complex as a new interaction site between the red cell membrane and the spectrin-based skeleton, the disruption of which might result in the stomato-spherocytosis typical of Rhnull red cells...
  33. ncbi request reprint When renal allografts turn DARC
    Stephan Segerer
    Medizinische Poliklinik, Klinikum Innenstadt der Universitat, Pettenkoferstrasse 8a, 80336 Munich, Germany
    Transplantation 75:1030-4. 2003
    ..Because DARC is expressed at the site of C4d deposition and might be involved in inflammatory cell recruitment, the authors evaluated the expression of DARC in different forms of human renal allograft rejection...
  34. pmc Phosphorylation and ankyrin-G binding of the C-terminal domain regulate targeting and function of the ammonium transporter RhBG
    Fabien Sohet
    INSERM, U665, Paris F 75015, the Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, Paris F 75015, France
    J Biol Chem 283:26557-67. 2008
    ..All these results led to a model in which targeting and ammonium transport function of RhBG are regulated by both phosphorylation and membrane skeleton binding of the C-terminal cytoplasmic domain...
  35. ncbi request reprint The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells
    Claude Lopez
    INSERM, U665, Institut National de la Transfusion Sanguine, Paris F 75015, France
    J Biol Chem 280:8221-8. 2005
    ....
  36. ncbi request reprint Fine mapping of the Duffy antigen binding site for the Plasmodium vivax Duffy-binding protein
    Christophe Tournamille
    INSERM U665, Institut National de la Transfusion Sanguine, Universite Paris 7 Denis Diderot, 6 rue Alexandre Cabanel, Paris F 75015, France
    Mol Biochem Parasitol 144:100-3. 2005
  37. pmc Ubc9 interacts with Lu/BCAM adhesion glycoproteins and regulates their stability at the membrane of polarized MDCK cells
    Emmanuel Collec
    INSERM, U665, Paris F 75015, France
    Biochem J 402:311-9. 2007
    ..Our results support a physiological role for the direct interaction between Lu gp and Ubc9 protein and reveal a role for this enzyme in regulating the stability of Lu gp at the cell membrane...
  38. ncbi request reprint Cell-surface expression of RhD blood group polypeptide is posttranscriptionally regulated by the RhAG glycoprotein
    Isabelle Mouro-Chanteloup
    Institut National de la Santé et de la Recherche Médicale U76, Faculte de Medecine Xavier Bichat, Paris, France
    Blood 100:1038-47. 2002
    ....