Affiliation: CHU de Nancy
- Is sugammadex economically viable for routine useThomas Fuchs-Buder
Departement d Anesthesie Reanimation, Université de Lorraine, Nancy, France
Curr Opin Anaesthesiol 25:217-20. 2012..However, compared with the classical acetylcholine esterase inhibitor-based reversal treatment costs are significantly higher. On the basis of the current literature, the cost-effectiveness of sugammadex will be evaluated...
- [Neuromuscular blockade with cisatracurium in infants andchildren. Its course under sevoflurane anesthesia]S Soltesz
Klinik für Anästhesie und Operative Intensivmedizin, Klinikum Leverkusen gGmbH, Dhunnberg 60, 51375 Leverkusen
Anaesthesist 51:374-7. 2002..To compare the onset, duration and maximum effect of 0.1 mg/kg cisatracurium during balanced anesthesia with sevoflurane and remifentanil between infants and children...
- Low-dose neostigmine to antagonise shallow atracurium neuromuscular block during inhalational anaesthesia: A randomised controlled trialThomas Fuchs-Buder
Centre Hospitalier Universitaire de Nancy Université de Lorraine, Nancy, Cedex, France
Eur J Anaesthesiol 30:594-8. 2013..Inhalational anaesthesia may enhance neuromuscular block and delay recovery. It is not known whether low doses of neostigmine are still effective in the context of inhalational anaesthesia...
- Concentration of rocuronium in cerebrospinal fluid of patients undergoing cerebral aneurysm clippingT Fuchs-Buder
Department of Anaesthesia and Critical Care, University of Saarland, Homburg Saar, Germany
Br J Anaesth 92:419-21. 2004....
- [Residual neuromuscular blockades. Clinical consequences, frequency and avoidance strategies]T Fuchs-Buder
Departement d Anesthesie Reanimation, Centre Hospitalier Universitaire de Nancy Brabois
Anaesthesist 55:7-16. 2006..g. TOF-watch) promises an adequate neuromuscular recovery from the effects of muscle relaxants...
- Good clinical research practice in pharmacodynamic studies of neuromuscular blocking agents II: the Stockholm revisionT Fuchs-Buder
Department of Anaesthesiology and Intensive Care Medicine, University of Nancy, France
Acta Anaesthesiol Scand 51:789-808. 2007..It is hoped that these guidelines will continue to help researchers in the field and assist the pharmaceutical industry and equipment manufacturers in enhancing the standards of the studies they sponsor...
- [Application of neuromuscular monitoring in Germany]T Fuchs-Buder
Departement d Anesthesie Reanimation, CHU Nancy Brabois, Nancy Brabois
Anaesthesist 57:908-14. 2008..In both hospital departments and private practices, clinical signs were the most often applied criteria for timing of reinjection of myorelaxants as well as for evaluation of neuromuscular recovery...
- Monitoring neuromuscular block: an updateT Fuchs-Buder
Department of Anaesthesia and Critical Care, Centre Hospitalier Universitaire, Nancy Brabois, France
Anaesthesia 64:82-9. 2009..The second part focuses on current developments and ongoing discussion. The authors describe the performance of acceleromyography and the need for initial calibration when using these quantitative devices...
- [Monitoring of neuromuscular block and prevention of residual paralysis]T Fuchs-Buder
Service d Anesthésie Réanimation Chirurgicale, Hopitaux de Brabois, CHU de Nancy, rue du Morvan, 54500 Vandoeuvre, France
Ann Fr Anesth Reanim 28:S46-50. 2009..The article aims to revise the principles of neuromuscular monitoring and evaluate whether its use is still mandatory when sugammadex is used...
- Antagonism of low degrees of atracurium-induced neuromuscular blockade: dose-effect relationship for neostigmineThomas Fuchs-Buder
Department of Anesthesia and Critical Care, Centre Hospitalier Universitaire, Institut de la Sante et de la Recherche Medicale, CIC EC CIE6, Nancy, France
Anesthesiology 112:34-40. 2010..The purpose of this study was to investigate the dose-effect relationship of neostigmine to antagonize residual paralysis corresponding to a TOF ratio of 0.4 and 0.6...
- [The use of neuromuscular monitoring in Germany]T Fuchs-Buder
Departement d Anesthesie Reanimation, Klinik fur Anasthesiologie, Universitat des Saarlandes
Anaesthesist 52:522-6. 2003..The aim of the study was to compare the use of muscle relaxants between German anaesthesia departments. In the present part of the presentation we focused on neuromuscular monitoring (NMM) and management of residual paralysis...
- Single acceleromyographic train-of-four, 100-Hertz tetanus or double-burst stimulation: which test performs better to detect residual paralysis?Amir Samet
Department of Anesthesia and Critical Care, CHU Nancy Brabois, Nancy, France
Anesthesiology 102:51-6. 2005..The second part of the study investigated whether uncalibrated acceleromyographic TOF ratio can predict time to complete recovery...
- Can acceleromyography detect low levels of residual paralysis? A probability approach to detect a mechanomyographic train-of-four ratio of 0.9Florent Capron
Department of Anesthesia and Critical Care, Centre Hospitalier Universitaire, Nancy Brabois, France
Anesthesiology 100:1119-24. 2004..The current study aimed to determine (1) the acceleromyographic TOF ratio that detects residual paralysis with a 95% probability, and (2) the impact of calibration and normalization on this predictive acceleromyographic value...
- [Postobstructif pulmonary oedema after endotracheal extubation at the recovery of general anaesthesia]A Samet
Departement d Anesthesie Reanimation, CHU de Brabois, rue du Morvan, 54511 Vandoeuvre les Nancy, France
Ann Fr Anesth Reanim 24:1287-90. 2005..The underlying pathophysiology seems to be the mechanical disruption of the alveolar-capillary membrane...
- [Pharmacology of sugammadex]C Meistelman
Departement d Anesthesie Reanimation, CHU de Brabois, rue du Morvan, 54500 Vandoeuvre Nancy, France
Ann Fr Anesth Reanim 28:S51-6. 2009..The use of sugammadex was not associated with recurrence of block when an adequate dose was administered...
- Use of reversal agents in day care procedures (with special reference to postoperative nausea and vomiting)T Fuchs-Buder
Department of Anaesthesia and Critical Care, University of the Saarland, D 66421 Homburg Saar, Germany
Eur J Anaesthesiol Suppl 23:53-9. 2001..Neuromuscular recovery should therefore be routinely monitored in ambulatory patients and residual paralysis prevented by reversing neuromuscular block...
- Laryngeal morbidity and quality of tracheal intubation: a randomized controlled trialThomas Mencke
Department of Anesthesia and Critical Care, University of the Saarland, Homburg Saar, Germany
Anesthesiology 98:1049-56. 2003..Several risk factors leading to laryngeal injury have been identified in the past. However, whether the quality of tracheal intubation affects their incidence or severity is still unclear...
- [Precurarization of succinylcholine with cisatracurium: the influence of the precurarization interval]T Mencke
Klinik für Anästhesiologie und Intensivmedizin, Universitatskliniken des Saarlandes, Homburg Saar, Germany
Anaesthesist 51:721-5. 2002..To determine the influence of two different pretreatment intervals, i.e. 3 and 6 min, on the efficacy of 0.01 mg/kg cisatracurium in preventing succinylcholine-induced fasciculations and myalgia...
- [Application of muscle relaxants for rapid-sequence induction of anaesthesia]R Hofmockel
Klinik für Anästhesiologie und Intensivtherapie, Universitat Rostock
Anaesthesist 52:516-21. 2003..It is the opinion of the authors that timing but also drugs with a slow onset (e.g., alcuronium and Pancuronium) are obsolete in the context of RSI...
- [Neuromuscular blockades. Agents, monitoring and antagonism]J U Schreiber
Klinik fur Anasthesiologie, Intensivmedizin und Schmerztherapie, Universitatsklinikum des Saarlandes, 66421 Homburg Saar
Anaesthesist 55:1225-35; quiz 1236. 2006..Therefore, the monitoring of neuromuscular recovery plays an important role in the prevention of postoperative complications due to residual paralysis. In case of residual paralysis, cholinesterase inhibitors are suitable for reversal...
- [Muscle relaxants in Germany 2005: a comparison of application customs in hospitals and private practices]H Fink
Klinik fur Anasthesiologie, Klinikum rechts der Isar, Technische Universitat, Ismaninger Strasse 22, 81675 Munchen
Anaesthesist 55:668-78. 2006..The results of this nationwide survey suggest that time pressure in combination with an increased specialization of anesthetists in private practice are the main factors for availability and use of muscle relaxants in routine anesthesia...
- [The use of muscle relaxants for routine induction of anesthesia in Germany]G Geldner
Klinik für Anästhesiologie und Intensivmedizin, Philipps Universitat Marburg, Germany
Anaesthesist 52:435-41. 2003..Precurarization, priming and timing are used frequently in patients not at risk of aspiration. This should be reduced by on-going teaching...
- [Application of muscle relaxants in Germany. A survey of German anaesthesia departments]M Blobner
Klinik fur Anaesthesiologie, Klinikum rechts der Isar, Technische Universitat Munchen, Munich
Anaesthesist 52:427-34. 2003..The aim of this study was to evaluate the use and application of muscle relaxants and neuromuscular monitoring in Germany...
- Risk of recurarization during retransfusion of autologous blood withdrawn after injection of muscle relaxants: a comparison of rocuronium and mivacuriumR G Rohling
Institute of Anesthesiology, University Hospital Zurich, Zurich, Switzerland
J Clin Anesth 15:85-90. 2003..The present study for the first time examined this risk for rocuronium and mivacurium...
- Tracheal intubation with and without muscular relaxationT Mencke
Eur J Anaesthesiol 23:354-5; author reply 355-6. 2006
- [Succinylcholine: once written off...]T Fuchs-Buder
Anaesthesist 51:564. 2002
- Cerebrospinal fluid concentrations of atracurium, laudanosine and vecuronium following clinical subarachnoid hemorrhageE Tassonyi
Department of Anesthesia, Pharmacology and Surgical Intensive Care, University Hospitals and University Medical Center CMU, Geneva, Switzerland
Acta Anaesthesiol Scand 46:1236-41. 2002..This study assessed the concentrations and the time course of passage of vecuronium, atracurium, and its metabolite laudanosine in the cerebrospinal fluid (CSF) of patients undergoing intracranial aneurysm clipping...
- Anesthesia for laparoscopic cholecystectomy: don't let evidence confuse youT Fuchs-Buder
Acta Anaesthesiol Scand 52:581-2. 2008
- Spontaneous movements, local reactions and pain on injection of rocuronium. A comparison between female and male patientsT Mencke
Department of Anaesthesia and Critical Care, University of the Saarland, Homburg/Saar, Germany
Acta Anaesthesiol Scand 45:1002-5. 2001..This was not associated with adverse clinical consequences for the patient's outcome...
- Blockade and activation of the human neuronal nicotinic acetylcholine receptors by atracurium and laudanosineF Chiodini
Department of Physiology, Geneva Medical Centre, Switzerland
Anesthesiology 94:643-51. 2001..CONCLUSION: Adverse effects observed during atracurium administration may be attributed, at least partly, to an interaction with neuronal nicotinic receptors...