Mathias Chamaillard

Summary

Affiliation: CHRU de Lille
Country: France

Publications

  1. ncbi request reprint Advances and perspectives in the genetics of inflammatory bowel diseases
    Mathias Chamaillard
    INSERM 0114, Hôpital Swynghedauw, Rue A Verhaeghe, F 59037 Lille, France
    Clin Gastroenterol Hepatol 4:143-51. 2006
  2. ncbi request reprint NODs in defence: from vulnerable antimicrobial peptides to chronic inflammation
    Laurent Peyrin-Biroulet
    INSERM U795, University of Lille 2, Huriez Hospital, Digestive Tract Diseases and Nutrition Department, F 59037 Lille, France
    Trends Microbiol 14:432-8. 2006
  3. pmc Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon
    Laurent Peyrin-Biroulet
    Institut National de la Sante et de la Recherche Medicale, U795, F 59037 Lille, France
    Proc Natl Acad Sci U S A 107:8772-7. 2010
  4. pmc CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease
    Suzanne Lesage
    Fondation Jean Dausset CEPH, 27 rue Juliette Dodu, 75010 Paris, France
    Am J Hum Genet 70:845-57. 2002
  5. ncbi request reprint Detection of antisynthetic mannoside antibodies (ASigmaMA) reveals heterogeneity in the ASCA response of Crohn's disease patients and contributes to differential diagnosis, stratification, and prediction
    Peggy Vandewalle-El Khoury
    INSERM, U799, Lille, France
    Am J Gastroenterol 103:949-57. 2008
  6. ncbi request reprint IBD serological panels: facts and perspectives
    Laurent Peyrin-Biroulet
    INSERM, U795, Lille, F 59037, France
    Inflamm Bowel Dis 13:1561-6. 2007
  7. ncbi request reprint NOD2 and defensins: translating innate to adaptive immunity in Crohn's disease
    Laurent Peyrin-Biroulet
    INSERM, U795, Lille, France
    J Endotoxin Res 13:135-9. 2007
  8. ncbi request reprint How NOD2 mutations predispose to Crohn's disease?
    Cecile Vignal
    INSERM, U 795, Lille, F 59037 France
    Microbes Infect 9:658-63. 2007
  9. ncbi request reprint Vascular and cellular stress in inflammatory bowel disease: revisiting the role of homocysteine
    Laurent Peyrin-Biroulet
    INSERM, U724, Laboratory of Cellular and Molecular Pathology in Nutrition, Faculty of Medicine, Nancy Universitè Vandoeuvre les Nancy, F 54511, France
    Am J Gastroenterol 102:1108-15. 2007
  10. pmc Mesenteric fat in Crohn's disease: a pathogenetic hallmark or an innocent bystander?
    Laurent Peyrin-Biroulet
    INSERM U795, F 59037 Lille Cedex, France
    Gut 56:577-83. 2007

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Advances and perspectives in the genetics of inflammatory bowel diseases
    Mathias Chamaillard
    INSERM 0114, Hôpital Swynghedauw, Rue A Verhaeghe, F 59037 Lille, France
    Clin Gastroenterol Hepatol 4:143-51. 2006
    ..This is a prerequisite for rational clinical management of IBD. Genetic, functional, serologic testing and development of therapeutics in IBD are discussed...
  2. ncbi request reprint NODs in defence: from vulnerable antimicrobial peptides to chronic inflammation
    Laurent Peyrin-Biroulet
    INSERM U795, University of Lille 2, Huriez Hospital, Digestive Tract Diseases and Nutrition Department, F 59037 Lille, France
    Trends Microbiol 14:432-8. 2006
    ..Further work is required to clarify how gastrointestinal CAPs are regulated and to assess their role in maintaining epithelial homeostasis and triggering adaptive immunity...
  3. pmc Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon
    Laurent Peyrin-Biroulet
    Institut National de la Sante et de la Recherche Medicale, U795, F 59037 Lille, France
    Proc Natl Acad Sci U S A 107:8772-7. 2010
    ..These findings support the development of PPARgamma-targeting therapeutic and/or nutritional approaches to prevent colonic inflammation by restoring antimicrobial immunity in CD...
  4. pmc CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease
    Suzanne Lesage
    Fondation Jean Dausset CEPH, 27 rue Juliette Dodu, 75010 Paris, France
    Am J Hum Genet 70:845-57. 2002
    ..These findings provide tools for a DNA-based test of susceptibility and for genetic counseling in inflammatory bowel disease...
  5. ncbi request reprint Detection of antisynthetic mannoside antibodies (ASigmaMA) reveals heterogeneity in the ASCA response of Crohn's disease patients and contributes to differential diagnosis, stratification, and prediction
    Peggy Vandewalle-El Khoury
    INSERM, U799, Lille, France
    Am J Gastroenterol 103:949-57. 2008
    ....
  6. ncbi request reprint IBD serological panels: facts and perspectives
    Laurent Peyrin-Biroulet
    INSERM, U795, Lille, F 59037, France
    Inflamm Bowel Dis 13:1561-6. 2007
    ..Better understanding of the serological response in IBD might also provide new insights into their epidemiology and pathophysiology...
  7. ncbi request reprint NOD2 and defensins: translating innate to adaptive immunity in Crohn's disease
    Laurent Peyrin-Biroulet
    INSERM, U795, Lille, France
    J Endotoxin Res 13:135-9. 2007
    ....
  8. ncbi request reprint How NOD2 mutations predispose to Crohn's disease?
    Cecile Vignal
    INSERM, U 795, Lille, F 59037 France
    Microbes Infect 9:658-63. 2007
    ..Further work should now focus on restoring abnormal NOD2 function by modulating antimicrobial function and regulatory mechanisms of the adaptive immune system...
  9. ncbi request reprint Vascular and cellular stress in inflammatory bowel disease: revisiting the role of homocysteine
    Laurent Peyrin-Biroulet
    INSERM, U724, Laboratory of Cellular and Molecular Pathology in Nutrition, Faculty of Medicine, Nancy Universitè Vandoeuvre les Nancy, F 54511, France
    Am J Gastroenterol 102:1108-15. 2007
    ....
  10. pmc Mesenteric fat in Crohn's disease: a pathogenetic hallmark or an innocent bystander?
    Laurent Peyrin-Biroulet
    INSERM U795, F 59037 Lille Cedex, France
    Gut 56:577-83. 2007
  11. ncbi request reprint Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
    Stephen E Girardin
    Unite de Pathogenie Microbienne Moleculaire, INSERM U389, Paris Cedex 15, France
    J Biol Chem 278:8869-72. 2003
    ..Additionally, the characterization of Nod2 as the first pathogen-recognition molecule that detects MDP will help to unravel the well known biological activities of this immunomodulatory compound...
  12. pmc Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases
    Mathias Chamaillard
    Fondation Jean Dausset, Centre d Etude du Polymorphisme Humain, 27 rue Juliette Dodu, 75010 Paris, France
    Proc Natl Acad Sci U S A 100:3455-60. 2003
    ....
  13. ncbi request reprint Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
    Koichi S Kobayashi
    Section of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA
    Science 307:731-4. 2005
    ..The Nod2 protein is thus a critical regulator of bacterial immunity within the intestine, providing a possible mechanism for Nod2 mutations in CD...
  14. ncbi request reprint [Regulatory role of Nod2 in intestinal immunity]
    Mathias Chamaillard
    University of Michigan Medical School, Ann Arbor 48109, USA
    Gastroenterol Clin Biol 28:1189-91. 2004
  15. pmc Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition
    Tsuyoshi Tanabe
    Department of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA
    EMBO J 23:1587-97. 2004
    ..These results provide new insights into the molecular function and regulation of NOD2 and related NOD family proteins...
  16. ncbi request reprint An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid
    Mathias Chamaillard
    Department of Pathology, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
    Nat Immunol 4:702-7. 2003
    ..Thus, NOD1 mediates selective recognition of bacteria through detection of iE-DAP-containing peptidoglycan...
  17. ncbi request reprint Clustering of Crohn's disease within affected sibships
    Jean Pierre Hugot
    Fondation Jean Dausset CEPH, Paris, France
    Eur J Hum Genet 11:179-84. 2003
    ..More generally, the CAST statistics may be widely applicable to estimate the involvement of environmental factors in the aetiology of other binary traits which may be observed in multiple members of the same sibship...