Laure Carcaillon

Summary

Country: France

Publications

  1. doi Low testosterone and the risk of dementia in elderly men: Impact of age and education
    Laure Carcaillon
    INSERM, CESP Centre for research in Epidemiology and Population Health, UMR S1018, Hormones and Cardiovascular disease, Villejuif, France Université Paris Sud 11, Kremlin Bicetre, France Electronic address
    Alzheimers Dement 10:S306-14. 2014
  2. pmc Sex differences in the association between serum levels of testosterone and frailty in an elderly population: the Toledo Study for Healthy Aging
    Laure Carcaillon
    Fundación para la Investigación Biomédica, Hospital Universitario de Getafe, Madrid, Spain
    PLoS ONE 7:e32401. 2012
  3. ncbi Diagnosis of Alzheimer's disease patients with rapid cognitive decline in clinical practice: interest of the Deco questionnaire
    L Carcaillon
    INSERM, CR897, Universite Victor Segalen Bordeaux 2, Bordeaux, France
    J Nutr Health Aging 15:361-6. 2011
  4. doi A subtest of the MMSE as a valid test of episodic memory? Comparison with the Free and Cued Reminding Test
    Laure Carcaillon
    INSERM, Unit 897, Bordeaux, France
    Dement Geriatr Cogn Disord 27:429-38. 2009
  5. doi Elevated plasma fibrin D-dimer as a risk factor for vascular dementia: the Three-City cohort study
    L Carcaillon
    INSERM Unit 780, Cardiovascular Epidemiology, Villejuif
    J Thromb Haemost 7:1972-8. 2009
  6. doi Increased thrombin generation is associated with acute ischemic stroke but not with coronary heart disease in the elderly: the Three-City cohort study
    Laure Carcaillon
    Institut National de la Sante et de la Recherche Medicale INSERM, Centre for research in Epidemiology and Population Health, U1018, Hormones and Cardiovascular disease, Villejuif, France
    Arterioscler Thromb Vasc Biol 31:1445-51. 2011
  7. doi High plasma estradiol interacts with diabetes on risk of dementia in older postmenopausal women
    Laure Carcaillon
    From Inserm L C, P Y S, CESP Centre for research in Epidemiology and Population Health, UMR S1018, Hormones and Cardiovascular disease, University Paris Sud, Villejuif Hôpital Bicêtre S B T, A G M, APHP, Service de Génétique Moléculaire, Pharmacogénétique et Hormonologie Kremlin Bicêtre Inserm UMR S693 S B T, A G M, Universite Paris Sud 11, Kremlin Bicêtre Inserm U1061 M L A, Universite Montpellier 1, Montpellier CMMR CHU Dijon O R, Dijon Université Victor Segalen Bordeaux 2 J F D, Bordeaux and Inserm U897 J F D, Epidemiology and Neuropsychology of Brain Aging, Bordeaux, France
    Neurology 82:504-11. 2014
  8. doi Gender differences in the prodromal signs of dementia: memory complaint and IADL-restriction. a prospective population-based cohort
    Karine Pérès
    INSERM, U897, Université Victor Segalen Bordeaux2, Bordeaux, France
    J Alzheimers Dis 27:39-47. 2011
  9. doi Endogenous oestradiol as a positive correlate of plasma fibrinogen among older postmenopausal women: a population-based study (the Three-City cohort study)
    Marianne Canonico
    Hormones and Cardiovascular disease, Univ Paris Sud, Villejuif, France
    Clin Endocrinol (Oxf) 77:905-10. 2012
  10. ncbi Fast cognitive decline at the time of dementia diagnosis: a major prognostic factor for survival in the community
    Laure Carcaillon
    INSERM, Unit 593, Bordeaux, France
    Dement Geriatr Cogn Disord 23:439-45. 2007

Detail Information

Publications21

  1. doi Low testosterone and the risk of dementia in elderly men: Impact of age and education
    Laure Carcaillon
    INSERM, CESP Centre for research in Epidemiology and Population Health, UMR S1018, Hormones and Cardiovascular disease, Villejuif, France Université Paris Sud 11, Kremlin Bicetre, France Electronic address
    Alzheimers Dement 10:S306-14. 2014
    ..The objective of this study was to examine the association of plasma estradiol and testosterone with risk for dementia in elderly men...
  2. pmc Sex differences in the association between serum levels of testosterone and frailty in an elderly population: the Toledo Study for Healthy Aging
    Laure Carcaillon
    Fundación para la Investigación Biomédica, Hospital Universitario de Getafe, Madrid, Spain
    PLoS ONE 7:e32401. 2012
    ..Although this association has been widely reported in older men, very few data are available in women. We studied the association between testosterone and frailty in women and assessed sex differences in this relationship...
  3. ncbi Diagnosis of Alzheimer's disease patients with rapid cognitive decline in clinical practice: interest of the Deco questionnaire
    L Carcaillon
    INSERM, CR897, Universite Victor Segalen Bordeaux 2, Bordeaux, France
    J Nutr Health Aging 15:361-6. 2011
    ..Patients with Alzheimer's disease (AD) who deteriorate rapidly are likely to have a poorer prognosis. There is a clear need for a clinical assessment tool to detect such a decline in newly diagnosed patients...
  4. doi A subtest of the MMSE as a valid test of episodic memory? Comparison with the Free and Cued Reminding Test
    Laure Carcaillon
    INSERM, Unit 897, Bordeaux, France
    Dement Geriatr Cogn Disord 27:429-38. 2009
    ..Episodic memory impairment is known to be the core of Alzheimer's disease (AD) dementia syndrome and one of the earliest domains to decline. However, episodic memory tests are long and expensive...
  5. doi Elevated plasma fibrin D-dimer as a risk factor for vascular dementia: the Three-City cohort study
    L Carcaillon
    INSERM Unit 780, Cardiovascular Epidemiology, Villejuif
    J Thromb Haemost 7:1972-8. 2009
    ..However, few studies have investigated these associations in the elderly. Moreover, vascular factors may be involved in dementia. Data on the relationship between hemostatic biomarkers and dementia remain scarce...
  6. doi Increased thrombin generation is associated with acute ischemic stroke but not with coronary heart disease in the elderly: the Three-City cohort study
    Laure Carcaillon
    Institut National de la Sante et de la Recherche Medicale INSERM, Centre for research in Epidemiology and Population Health, U1018, Hormones and Cardiovascular disease, Villejuif, France
    Arterioscler Thromb Vasc Biol 31:1445-51. 2011
    ..Whether changes in this biomarker are relevant to arterial disease remains unknown. We investigated the association of thrombin generation with coronary heart disease (CHD) and acute ischemic stroke (AIS) in the elderly...
  7. doi High plasma estradiol interacts with diabetes on risk of dementia in older postmenopausal women
    Laure Carcaillon
    From Inserm L C, P Y S, CESP Centre for research in Epidemiology and Population Health, UMR S1018, Hormones and Cardiovascular disease, University Paris Sud, Villejuif Hôpital Bicêtre S B T, A G M, APHP, Service de Génétique Moléculaire, Pharmacogénétique et Hormonologie Kremlin Bicêtre Inserm UMR S693 S B T, A G M, Universite Paris Sud 11, Kremlin Bicêtre Inserm U1061 M L A, Universite Montpellier 1, Montpellier CMMR CHU Dijon O R, Dijon Université Victor Segalen Bordeaux 2 J F D, Bordeaux and Inserm U897 J F D, Epidemiology and Neuropsychology of Brain Aging, Bordeaux, France
    Neurology 82:504-11. 2014
    ..We aimed to investigate the impact of endogenous estradiol (E2) on dementia and to evaluate the contribution of vascular risk factors and inflammatory and blood coagulation markers to this association...
  8. doi Gender differences in the prodromal signs of dementia: memory complaint and IADL-restriction. a prospective population-based cohort
    Karine Pérès
    INSERM, U897, Université Victor Segalen Bordeaux2, Bordeaux, France
    J Alzheimers Dis 27:39-47. 2011
    ..To conclude, women would report the first symptoms very early in the process by SMC, whereas men would tend to later report their difficulties and only in terms of IADL-restriction...
  9. doi Endogenous oestradiol as a positive correlate of plasma fibrinogen among older postmenopausal women: a population-based study (the Three-City cohort study)
    Marianne Canonico
    Hormones and Cardiovascular disease, Univ Paris Sud, Villejuif, France
    Clin Endocrinol (Oxf) 77:905-10. 2012
    ..However, whether endogenous sex steroid hormones influence the plasma fibrinogen concentrations among postmenopausal women remains unclear...
  10. ncbi Fast cognitive decline at the time of dementia diagnosis: a major prognostic factor for survival in the community
    Laure Carcaillon
    INSERM, Unit 593, Bordeaux, France
    Dement Geriatr Cogn Disord 23:439-45. 2007
    ..Our study aimed at confirming the concept of fast decliners at the time of Alzheimer's disease (AD) diagnosis which best predicts mortality, in an unselected sample...
  11. doi Clustering and switching processes in semantic verbal fluency in the course of Alzheimer's disease subjects: results from the PAQUID longitudinal study
    Nadine Raoux
    INSERM, U897, Bordeaux Cedex, France University Victor Segalen Bordeaux 2, Bordeaux Cedex, France
    Cortex 44:1188-96. 2008
    ..Therefore the results support the hypothesis that impaired shifting abilities - rather than semantic memory storage degradation - could explain the early decline in semantic fluency performance occurring in the predementia phase of AD...
  12. pmc Multiple imputation for estimating hazard ratios and predictive abilities in case-cohort surveys
    Helena Marti
    INSERM, CESP Centre for research in Epidemiology and Population Health, U1018, Biostatistics team, F 94807 Villejuif, France
    BMC Med Res Methodol 12:24. 2012
    ..However, case-cohort studies represent a special type of incomplete data, and methods for analyzing incomplete data should be appropriate, in particular multiple imputation (MI)...
  13. pmc Postmenopausal Hormone Therapy and Risk of Stroke: Impact of the Route of Estrogen Administration and Type of Progestogen
    Marianne Canonico
    From the Université Paris Saclay, Univ Paris Sud, UVSQ, Centre de Recheche en Epidémiologie et Santé des Populations, Inserm UMRS1018, Villejuif, France M C, E O, A S M, A E, P Y S Institut de veille sanitaire InVS, Département des Maladies Chroniques et des, Traumatismes, F 94415 Saint Maurice, France L C APHP, Hôpitaux Paris Centre, Unité de gynécologie endocrinienne, Paris, 75014, France et Université Paris Descartes G P B Université Paris Saclay, Univ Paris Sud, UVSQ, Biostatistics, Biomathematics, Pharmacoepidemiology and Infectious Diseases, INSERM UMRS1181, Villejuif, France P T B and Institut Pasteur, Paris, France P T B
    Stroke 47:1734-41. 2016
    ..However, the differential association of oral and transdermal estrogens with stroke remains poorly investigated. Furthermore, there are no data regarding the impact of progestogens...
  14. doi Carotid plaque as a predictor of dementia in older adults: the Three-City Study
    Laure Carcaillon
    INSERM, CESP Centre for research in Epidemiology and Population Health, UMR S1018, Hormones and Cardiovascular disease, University Paris Sud, Villejuif, France
    Alzheimers Dement 11:239-48. 2015
    ..We examined the association between carotid plaques (CP) and common carotid intima media thickness (CCA-IMT) with incident dementia and its subtypes, and their added value for dementia risk prediction...
  15. doi Is frailty a prodromal stage of vascular dementia? Results from the Three-City Study
    José Alberto Avila-Funes
    Department of Geriatrics, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico
    J Am Geriatr Soc 60:1708-12. 2012
    ..To investigate the relationship between frailty and incident vascular dementia (VaD)...
  16. ncbi Vasodilators and nootropics as predictors of dementia and mortality in the PAQUID cohort
    Jean Francois Dartigues
    INSERM U 593, Universite de Bordeaux 2, Bordeaux, France
    J Am Geriatr Soc 55:395-9. 2007
    ..To assess the effects of treatment for memory impairment and the Ginkgo biloba extract (EGb 761) on dementia, mortality, and survival without dementia...
  17. doi Higher level of systemic C-reactive protein is independently predictive of coronary heart disease in older community-dwelling adults: the three-city study
    Celine Straczek
    INSERM U970, Paris Cardiovascular Research Center, Paris, France
    J Am Geriatr Soc 58:129-35. 2010
    ..To assess the association between systemic C-reactive protein (CRP) and incident coronary heart disease (CHD) in community-dwelling elderly people...
  18. doi Synergism between oral estrogen therapy and cytochrome P450 3A5*1 allele on the risk of venous thromboembolism among postmenopausal women
    Marianne Canonico
    Institut National de la Santé et de la Recherche Médicale INSERM Unit 780 U780, Cardiovascular Epidemiology Section, 16 Avenue Paul Vaillant Couturier, Villejuif Cedex, F 94807 France
    J Clin Endocrinol Metab 93:3082-7. 2008
    ..This effect may be modulated by the expression of cytochromes P450 3A5 (CYP3A5) and 1A2 (CYP1A2) which are involved in the hepatic metabolism of estrogens...
  19. doi A meta-analysis of genome-wide association studies identifies ORM1 as a novel gene controlling thrombin generation potential
    Ares Rocañín-Arjó
    Pierre and Marie Curie University, INSERM, UMR_S 1166, Paris, France
    Blood 123:777-85. 2014
    ..These results pave the way for novel mechanistic pathways and therapeutic perspectives in the etiology of thrombin-related disorders. ..
  20. pmc Searching for an operational definition of frailty: a Delphi method based consensus statement: the frailty operative definition-consensus conference project
    Leocadio Rodriguez-Manas
    Hospital Universitario de Getafe, Madrid, Spain
    J Gerontol A Biol Sci Med Sci 68:62-7. 2013
    ..There is no consensus regarding the definition of frailty for clinical uses...
  21. doi Postmenopausal hormone therapy and risk of idiopathic venous thromboembolism: results from the E3N cohort study
    Marianne Canonico
    INSERM Unit 780, Cardiovascular Epidemiology Section, Cedex, France
    Arterioscler Thromb Vasc Biol 30:340-5. 2010
    ..Although recent data showed transdermal estrogens may be safe with respect to thrombotic risk, the impact of the route of estrogen administration and concomitant progestogens is not fully established...