Helene Budzinski

Summary

Country: France

Publications

  1. ncbi request reprint Analysis of hormonal steroids in fish plasma and bile by coupling solid-phase extraction to GC/MS
    H Budzinski
    Laboratoire de Physico et Toxico Chimie LPTC, UMR 5472 CNRS, Universite Bordeaux I, 351 Cours de la Liberation, 33405 Talence Cedex, France
    Anal Bioanal Chem 386:1429-39. 2006
  2. ncbi request reprint Analytical development for analysis of pharmaceuticals in water samples by SPE and GC-MS
    Anne Togola
    University of Bordeaux 1, CNRS, LPTC, UMR 5472, 351 Crs de la Liberation, 33405, Talence, France
    Anal Bioanal Chem 388:627-35. 2007
  3. doi request reprint Comparative study of different exposure routes on the biotransformation and genotoxicity of PAHs in the flatfish species, Scophthalmus maximus
    Marie Le Dû-Lacoste
    Oceanic and Continental Environments and Paleoenvironments, EPOC, UMR 5805, CNRS, Laboratory of Physico and Toxico Chemistry of the Environment, LPTC, Universite de Bordeaux, 351 Cours de la Liberation, 33405 Talence Cedex, France
    Environ Sci Pollut Res Int 20:690-707. 2013
  4. ncbi request reprint Microcosm tributyltin bioaccumulation and multibiomarker assessment in the blue mussel Mytilus edulis
    Marie Hélène Devier
    Laboratoire de Physico et Toxicochimie des Systèmes Naturels, UMR 5472 CNRS, Universite de Bordeaux 1, 351 Cours de la Liberation, 33405 Talence Cedex, France
    Environ Toxicol Chem 22:2679-87. 2003
  5. ncbi request reprint Biomonitoring in a clean and a multi-contaminated estuary based on biomarkers and chemical analyses in the endobenthic worm Nereis diversicolor
    Cyril Durou
    CNRS, Universite de Nantes, Pôle Mer et Littoral, SMAB, 2 rue de la Houssiniere, BP 92208, F 44322 Nantes Cedex 3, France
    Environ Pollut 148:445-58. 2007
  6. ncbi request reprint Determination of steroidal hormone profiles along the Jalle d'Eysines River (near Bordeaux, France)
    Pierre Labadie
    Laboratoire de Physico and Toxico Chimie des Systèmes Naturels, UMR 5472 CNRS, Universite Bordeaux I, 351 Cours de la Liberation, 33405 Talence, France
    Environ Sci Technol 39:5113-20. 2005
  7. doi request reprint Uptake and elimination, and effect of estrogen-like contaminants in estuarine copepods: an experimental study
    Kevin Cailleaud
    University of Bordeaux 1, CNRS, ISM LPTC UMR 5255, 351 Cours de la Liberation, 33405, Talence, France
    Environ Sci Pollut Res Int 18:226-36. 2011
  8. doi request reprint Pollution biomonitoring in the Bizerte lagoon (Tunisia), using combined chemical and biomarker analyses in grass goby, Zosterisessor ophiocephalus (Teleostei, Gobiidae)
    Badreddine Barhoumi
    Laboratory of Environmental Analytical Chemistry 05 UR 12 03, University of Carthage, Faculty of Sciences of Bizerte, 7021, Zarzouna, Bizerte, Tunisia University of Bordeaux, CNRS, UMR EPOC 5805, Avenue des Facultes, 33405 Talence Cedex, France
    Mar Environ Res 101:184-95. 2014
  9. ncbi request reprint Alteration of steroid hormone profile in juvenile turbot (Psetta maxima) as a consequence of short-term exposure to 17alpha-ethynylestradiol
    Pierre Labadie
    Laboratoire de Physico and Toxico Chimie des Systèmes Naturels, LPTC, UMR 5472 CNRS, Bat A 12, Universite Bordeaux I, 351 Cours de la Liberation, 33405 Talence, France
    Chemosphere 64:1274-86. 2006
  10. doi request reprint PBDE and PCB contamination of eels from the Gironde estuary: from glass eels to silver eels
    Nathalie Tapie
    Universite Bordeaux 1, Laboratoire de Physico Toxico Chimie de l environnement, Institut des Sciences Moléculaires ISM UMR 5255 CNRS, 341 cours de la Libération, Talence, France
    Chemosphere 83:175-85. 2011

Collaborators

Detail Information

Publications40

  1. ncbi request reprint Analysis of hormonal steroids in fish plasma and bile by coupling solid-phase extraction to GC/MS
    H Budzinski
    Laboratoire de Physico et Toxico Chimie LPTC, UMR 5472 CNRS, Universite Bordeaux I, 351 Cours de la Liberation, 33405 Talence Cedex, France
    Anal Bioanal Chem 386:1429-39. 2006
    ..1 to 0.4 ng/g in fish plasma and from 1.6 to 14 ng/g in fish bile. The developed method was successfully applied to the determination of plasma steroids in flounders (Platichthys flesus) collected from two French estuaries...
  2. ncbi request reprint Analytical development for analysis of pharmaceuticals in water samples by SPE and GC-MS
    Anne Togola
    University of Bordeaux 1, CNRS, LPTC, UMR 5472, 351 Crs de la Liberation, 33405, Talence, France
    Anal Bioanal Chem 388:627-35. 2007
    ..Concentrations varied from several dozens of nanograms per liter for surface waters to several hundreds of nanograms per liter for wastewaters...
  3. doi request reprint Comparative study of different exposure routes on the biotransformation and genotoxicity of PAHs in the flatfish species, Scophthalmus maximus
    Marie Le Dû-Lacoste
    Oceanic and Continental Environments and Paleoenvironments, EPOC, UMR 5805, CNRS, Laboratory of Physico and Toxico Chemistry of the Environment, LPTC, Universite de Bordeaux, 351 Cours de la Liberation, 33405 Talence Cedex, France
    Environ Sci Pollut Res Int 20:690-707. 2013
    ..The quantification of PAH metabolites in bile and DNA damage in erythrocytes appear to be suitable for environmental monitoring of marine pollution either in the case of accidental oil spills or sediment contamination...
  4. ncbi request reprint Microcosm tributyltin bioaccumulation and multibiomarker assessment in the blue mussel Mytilus edulis
    Marie Hélène Devier
    Laboratoire de Physico et Toxicochimie des Systèmes Naturels, UMR 5472 CNRS, Universite de Bordeaux 1, 351 Cours de la Liberation, 33405 Talence Cedex, France
    Environ Toxicol Chem 22:2679-87. 2003
    ..No significant changes were observed in the measured enzyme activities or in TBARS concentration after the 4-d TBT exposure...
  5. ncbi request reprint Biomonitoring in a clean and a multi-contaminated estuary based on biomarkers and chemical analyses in the endobenthic worm Nereis diversicolor
    Cyril Durou
    CNRS, Universite de Nantes, Pôle Mer et Littoral, SMAB, 2 rue de la Houssiniere, BP 92208, F 44322 Nantes Cedex 3, France
    Environ Pollut 148:445-58. 2007
    ..The use of GST and AChE activities and energy reserve concentrations as biomarkers is validated in the field in this keystone species...
  6. ncbi request reprint Determination of steroidal hormone profiles along the Jalle d'Eysines River (near Bordeaux, France)
    Pierre Labadie
    Laboratoire de Physico and Toxico Chimie des Systèmes Naturels, UMR 5472 CNRS, Universite Bordeaux I, 351 Cours de la Liberation, 33405 Talence, France
    Environ Sci Technol 39:5113-20. 2005
    ..Therefore, it is likely that biodegradation plays a major role in the removal of steroids from the river and the different decay rates are probably related to differences in bacterial activity within the river...
  7. doi request reprint Uptake and elimination, and effect of estrogen-like contaminants in estuarine copepods: an experimental study
    Kevin Cailleaud
    University of Bordeaux 1, CNRS, ISM LPTC UMR 5255, 351 Cours de la Liberation, 33405, Talence, France
    Environ Sci Pollut Res Int 18:226-36. 2011
    ..Moreover, the elimination of these compounds in copepods from the Seine Estuary has been investigated by measuring concentrations after 1 week in clean water in comparison to background levels...
  8. doi request reprint Pollution biomonitoring in the Bizerte lagoon (Tunisia), using combined chemical and biomarker analyses in grass goby, Zosterisessor ophiocephalus (Teleostei, Gobiidae)
    Badreddine Barhoumi
    Laboratory of Environmental Analytical Chemistry 05 UR 12 03, University of Carthage, Faculty of Sciences of Bizerte, 7021, Zarzouna, Bizerte, Tunisia University of Bordeaux, CNRS, UMR EPOC 5805, Avenue des Facultes, 33405 Talence Cedex, France
    Mar Environ Res 101:184-95. 2014
    ..On the basis of these results, and due to its ecological characteristics, the grass goby appears a suitable indicator species for pollution biomonitoring in coastal marine areas along the Mediterranean Sea. ..
  9. ncbi request reprint Alteration of steroid hormone profile in juvenile turbot (Psetta maxima) as a consequence of short-term exposure to 17alpha-ethynylestradiol
    Pierre Labadie
    Laboratoire de Physico and Toxico Chimie des Systèmes Naturels, LPTC, UMR 5472 CNRS, Bat A 12, Universite Bordeaux I, 351 Cours de la Liberation, 33405 Talence, France
    Chemosphere 64:1274-86. 2006
    ..These results indicate that juvenile male turbots are susceptible to hormonal imbalance as a consequence of short-term exposure to environmentally relevant EE2 levels...
  10. doi request reprint PBDE and PCB contamination of eels from the Gironde estuary: from glass eels to silver eels
    Nathalie Tapie
    Universite Bordeaux 1, Laboratoire de Physico Toxico Chimie de l environnement, Institut des Sciences Moléculaires ISM UMR 5255 CNRS, 341 cours de la Libération, Talence, France
    Chemosphere 83:175-85. 2011
    ..These results are worrying for the local people who regularly eat eels caught in the Gironde estuary...
  11. doi request reprint Simple methodology coupling microwave-assisted extraction to SPE/GC/MS for the analysis of natural steroids in biological tissues: application to the monitoring of endogenous steroids in marine mussels Mytilus sp
    Marie Hélène Devier
    Universite de Bordeaux, UMR 5255, ISM, Groupe LPTC, 351 Cours de la Liberation, Talence F 33405, France
    Anal Chim Acta 657:28-35. 2010
    ..in the Bay. The current challenge for the determination of natural steroids in aquatic invertebrates is also briefly discussed...
  12. doi request reprint Developmental toxicity of PAH mixtures in fish early life stages. Part II: adverse effects in Japanese medaka
    Florane Le Bihanic
    UMR CNRS 5805 EPOC, University of Bordeaux, Avenue des Facultes, 33405, Talence Cedex, France
    Environ Sci Pollut Res Int 21:13732-43. 2014
    ..This study highlights the potential risks posed by environmental mixtures of alkylated and low molecular weight PAHs to early stages of fish development...
  13. ncbi request reprint Alteration of steroid hormone balance in juvenile turbot (Psetta maxima) exposed to nonylphenol, bisphenol A, tetrabromodiphenyl ether 47, diallylphthalate, oil, and oil spiked with alkylphenols
    Pierre Labadie
    Laboratoire de Physico and Toxico Chimie des Systèmes Naturels LPTC, UMR 5472 CNRS, Universite Bordeaux I, 351 Cours de la Liberation, Talence, France
    Arch Environ Contam Toxicol 50:552-61. 2006
    ..Overall, these two chemicals seemingly disrupted the activity of some steroidogenesis enzymes, leading to serious hormonal imbalance in juvenile turbot...
  14. doi request reprint Biliary PAH metabolites, EROD activity and DNA damage in dab (Limanda limanda) from Seine Estuary (France)
    Marie Hélène Devier
    Oceanic and Continental Environments and Paleoenvironments, UMR 5805 CNRS, Laboratory of Physico and Toxico Chemistry of the Environment, Universite de Bordeaux, 351 Cours de la Liberation, 33405, Talence Cedex, France
    Environ Sci Pollut Res Int 20:708-22. 2013
    ....
  15. doi request reprint Developmental toxicity of PAH mixtures in fish early life stages. Part I: adverse effects in rainbow trout
    Florane Le Bihanic
    University of Bordeaux, EPOC, UMR CNRS 5805, 351 Cours de la Liberation, 33405, Talence Cedex, France
    Environ Sci Pollut Res Int 21:13720-31. 2014
    ..The minimal concentration causing developmental defects was as low as 0.7 μg g(-1) sum of PAHs, indicating the high sensitivity of the assay and validating its use for toxicity assessment of particle-bound pollutants...
  16. ncbi request reprint Solid-phase extraction and purification for the quantification of polycyclic aromatic hydrocarbon metabolites in fish bile
    Olivier Mazéas
    Laboratoire de Physico et Toxico Chimie des Systèmes Naturels, UMR 5472 CNRS, Universite Bordeaux I, 351, Cours de la Liberation, 33405 Talence, France
    Anal Bioanal Chem 383:985-90. 2005
    ..Different PAH metabolites could be detected in those natural samples and their quantification allowed us to distinguish different levels of fish exposure...
  17. doi request reprint Ultra-trace analysis of hormones, pharmaceutical substances, alkylphenols and phthalates in two French natural mineral waters
    Marie Hélène Devier
    Environnements et Paléoenvironnements Océaniques et Continentaux EPOC, UMR 5805 CNRS, Laboratoire de Physico et Toxico Chimie de l Environnement LPTC, Universite de Bordeaux, 351 Cours de la Liberation, 33405 Talence Cedex, France
    Sci Total Environ 443:621-32. 2013
    ....
  18. ncbi request reprint Development of polar organic integrative samplers for analysis of pharmaceuticals in aquatic systems
    Anne Togola
    University of Bordeaux 1, ISM LPTC, UMR 5255 CNRS, 351 Cours de la Liberation, 33405, Talence, France
    Anal Chem 79:6734-41. 2007
    ..The uniformity or reproducibility of the sampling matrix and, on the other hand, the ability to detect compounds at low concentration levels below detection limits of discrete sampling have been highlighted...
  19. doi request reprint Environmental Occurrence of Perfluoroalkyl Acids and Novel Fluorotelomer Surfactants in the Freshwater Fish Catostomus commersonii and Sediments Following Firefighting Foam Deployment at the Lac-Mégantic Railway Accident
    Gabriel Munoz
    Universite de Bordeaux, EPOC, UMR 5805, LPTC Research Group, 351 Cours de la Liberation, F 33400 Talence, France
    Environ Sci Technol . 2017
    ..Levels of PFAAs remained moderate in fish muscle (e.g...
  20. doi request reprint Transcriptional responses and embryotoxic effects induced by pyrene and methylpyrene in Japanese medaka (Oryzias latipes) early life stages exposed to spiked sediments
    Iris Barjhoux
    EPOC UMR CNRS 5805, Universite de Bordeaux, Avenue des Facultes, 33405, Talence, Cedex, France
    Environ Sci Pollut Res Int 21:13850-66. 2014
    ..Results reported in the present study have brought new insights into the modes of action of Pyr, and the effects of MePyr exposure have been investigated in fish ELS for the first time...
  21. ncbi request reprint Development of an analytical procedure for determination of selected estrogens and progestagens in water samples
    Pierre Labadie
    Laboratoire de Physico Chimie and Toxico Chimie des systèmes naturels LPTC, UMR 5472 CNRS, Universite Bordeaux I, 351 Cours de la Liberation, 33405, Talence, France
    Anal Bioanal Chem 381:1199-205. 2005
    ..Overall, for 162 out of 168 measurements levels were below the detection limits of the developed procedure...
  22. ncbi request reprint Multi-residue analysis of pharmaceutical compounds in aqueous samples
    Anne Togola
    University of Bordeaux 1, CNRS, ISM LPTC, UMR 5255, 351 Crs de la Liberation, 33405 Talence, France
    J Chromatogr A 1177:150-8. 2008
    ..In both cases, the level of pharmaceuticals was totally unknown. Results obtained have demonstrated the suitability of the method for multi-residue analysis of different types of water matrices...
  23. doi request reprint Uptake and elimination of hydrophobic organic contaminants in estuarine copepods: an experimental study
    Kevin Cailleaud
    Universite Bordeaux 1, CNRS, ISM LPTC UMR 5255, 351 Cours de la Liberation, 33405 Talence, France
    Environ Toxicol Chem 28:239-46. 2009
    ..These results suggest the importance of copepods in the biogeochemical cycles of hydrophobic organic contaminants in estuarine ecosystems...
  24. ncbi request reprint Consequences of treated water recycling as regards pharmaceuticals and drugs in surface and ground waters of a medium-sized Mediterranean catchment
    Marion Rabiet
    Laboratoire Hydrosciences Montpellier, UMR 5569, CNRS, IRD, University of Montpellier I and II, cc MSE, 34095 Montpellier 5, France
    Environ Sci Technol 40:5282-8. 2006
    ..The monitoring of pharmaceuticals along the Lergue River shows that dilution is sufficient to decrease pharmaceutical values...
  25. ncbi request reprint Spatio-temporal dynamics of per and polyfluoroalkyl substances (PFASs) and transfer to periphytic biofilm in an urban river: case-study on the River Seine
    Gabriel Munoz
    University of Bordeaux, EPOC, UMR 5805, LPTC Research Group, 351 Cours de la Liberation, F 33400, Talence, France
    Environ Sci Pollut Res Int . 2016
    ..Biofilm community characteristics (C/N ratio) may also be an influential determinant of PFAS bioaccumulation. Graphical abstract ᅟ...
  26. doi request reprint Detecting the exposure to Cd and PCBs by means of a non-invasive transcriptomic approach in laboratory and wild contaminated European eels (Anguilla anguilla)
    Lucie Baillon
    Univ Bordeaux, UMR EPOC CNRS 5805, F 33400, Talence, France
    Environ Sci Pollut Res Int 23:5431-41. 2016
    ..This study thus highlights the applicability and usefulness of performing gene transcription assays on non-invasive tissue sampling in order to detect the in situ exposure to Cd and PCBs in fish...
  27. doi request reprint Psychotropic drugs in mixture alter swimming behaviour of Japanese medaka (Oryzias latipes) larvae above environmental concentrations
    Axelle Chiffre
    Laboratoire EPOC, UMR CNRS 5805, Universite de Bordeaux, Avenue des Facultes, 33405, Talence Cedex, France
    Environ Sci Pollut Res Int 23:4964-77. 2016
    ..Realistic environmental mixture of the six psychotropic compounds induced disruption of larval locomotor behaviour at concentrations about 10- to 100-fold greater than environmental concentrations...
  28. doi request reprint Development of a reference artificial sediment for chemical testing adapted to the MELA sediment contact assay
    Florane Le Bihanic
    University of Bordeaux, EPOC UMR CNRS 5805, 33405, Avenue des Facultes, Talence Cedex, France
    Environ Sci Pollut Res Int 21:13689-702. 2014
    ..Studies with other hydrophobic and metallic contaminants and mixtures should be performed to further validate this artificial sediment...
  29. ncbi request reprint Analysis of polycyclic aromatic hydrocarbons adsorbed on particles of atmospheric interest using pressurised fluid extraction
    Emilie Perraudin
    Laboratoire de Physico et Toxico Chimie des Systèmes Naturels, UMR 5472 CNRS, Universite Bordeaux I, 33405 Talence Cedex, France
    Anal Bioanal Chem 383:122-31. 2005
    ..Extraction conditions (toluene, 130 degrees C, 130 bar, 2 x 8-min static cycles) were optimised to extract PAHs when strongly interacting with solid matrices and were validated by the analysis of two PAH-certified materials...
  30. ncbi request reprint One-year monitoring survey of organic compounds (PAHs, PCBs, TBT), heavy metals and biomarkers in blue mussels from the Arcachon Bay, France
    Marie Hélène Devier
    Laboratoire de Physico et Toxicochimie des Systemes Naturels LPTC, UMR 5472 CNRS, Universite de Bordeaux 1, 351 Cours de la Liberation, 33405 Talence Cedex, France
    J Environ Monit 7:224-40. 2005
    ..It is the first time that such an integrated monitoring is performed in the Arcachon Bay, also taking into account seasonal variations of chemical contents and biomarkers levels in mussel tissues...
  31. doi request reprint ASE extraction method for simultaneous carbon and nitrogen stable isotope analysis in soft tissues of aquatic organisms
    Nathalie Bodin
    ISM LPTC, UMR 5255 CNRS, Universite de Bordeaux 1, 351 Cours de la Liberation, 33405 Talence, France
    Anal Chim Acta 643:54-60. 2009
    ..The results were discussed in terms of lipid extraction efficiency as well as delta13C and delta15N variability...
  32. doi request reprint Quantitative analysis of poly- and perfluoroalkyl compounds in water matrices using high resolution mass spectrometry: optimization for a laser diode thermal desorption method
    Gabriel Munoz
    Universite de Bordeaux, EPOC, UMR 5805, LPTC, 351 Cours de la Liberation, F 33400 Talence, France Department of Chemistry, Universite de Montreal, C P 6128, Succursale Centre Ville, Montreal, QC H3C 3J7, Canada
    Anal Chim Acta 881:98-106. 2015
    ....
  33. doi request reprint Spatial distribution and partitioning behavior of selected poly- and perfluoroalkyl substances in freshwater ecosystems: a French nationwide survey
    Gabriel Munoz
    University of Bordeaux, EPOC, UMR 5805, LPTC, 351 Cours de la Liberation, F 33400 Talence, France
    Sci Total Environ 517:48-56. 2015
    ..Multiple regression results suggest that PFAS levels in the dissolved phase and sediment characteristics (organic carbon fraction and grain size) may be significant controlling factors of PFAS levels in the sediment...
  34. doi request reprint Transcriptome profile analysis reveals specific signatures of pollutants in Atlantic eels
    Lucie Baillon
    Univ Bordeaux, UMR EPOC CNRS 5805, 33400, Talence, France
    Ecotoxicology 24:71-84. 2015
    ..Genes associated with HSI were involved in protein, lipid and iron metabolisms. Our study proposes specific gene signatures of pollutants and their impacts in fish exposed to multi-stress conditions. ..
  35. doi request reprint Development of solid-phase microextraction to study dissolved organic matter--polycyclic aromatic hydrocarbon interactions in aquatic environment
    Chloé de Perre
    Universite de Bordeaux, UMR 5805, EPOC LPTC, 351 Cours de la Liberation, Talence Cedex F 33405, France CNRS, UMR 5805, EPOC LPTC, F 33405 Talence Cedex, France
    Anal Chim Acta 807:51-60. 2014
    ....
  36. doi request reprint Assessment of pollution in the Bizerte lagoon (Tunisia) by the combined use of chemical and biochemical markers in mussels, Mytilus galloprovincialis
    Badreddine Barhoumi
    University of Carthage, Faculty of Sciences of Bizerte, Laboratory of Environmental Analytical Chemistry 05 UR 12 03, 7021 Zarzouna, Bizerte, Tunisia University of Bordeaux, CNRS, UMR EPOC 5805, Avenue des Facultes, 33405 Talence Cedex, France
    Mar Pollut Bull 84:379-90. 2014
    ..Our results confirmed the usefulness of combining biomarker and chemical analyses in mussels to assess chemical pollution in the Bizerte lagoon. ..
  37. doi request reprint Development of the performance reference compound approach for the calibration of "polar organic chemical integrative sampler" (POCIS)
    Angel Belles
    EPOC, UMR 5805, University of Bordeaux, 33400, Talence, France
    Anal Bioanal Chem 406:1131-40. 2014
    ....
  38. ncbi request reprint Effects of salinity and temperature on the expression of enzymatic biomarkers in Eurytemora affinis (Calanoida, Copepoda)
    K Cailleaud
    Universite Bordeaux 1, CNRS, LPTC UMR 5472 Laboratory of Physico and Toxico Chemistry, 351 Crs de la Liberation, 33405 Talence, France
    Comp Biochem Physiol A Mol Integr Physiol 147:841-9. 2007
    ....
  39. doi request reprint Fast and efficient extraction methods for the analysis of polychlorinated biphenyls and polybrominated diphenyl ethers in biological matrices
    N Tapie
    Laboratoire de Physico Toxico Chimie des systèmes naturels UMR 5472 CNRS, Universite Bordeaux 1, 341 cours de la Libération, 33405, Talence, France
    Anal Bioanal Chem 391:2169-77. 2008
    ..These methods allowed at least 24 samples to be handled per day, and could easily be used for routine analysis...
  40. ncbi request reprint Multi-residue analysis of polycyclic aromatic hydrocarbons, polychlorobiphenyls, and organochlorine pesticides in marine sediments
    S Thompson
    Laboratory of Environmental and Toxicological Chemistry, UMR 5472 CNRS, University of Bordeaux, Talence, France
    Anal Bioanal Chem 372:196-204. 2002
    ..Quantification problems encountered for two pesticides (cis-chlordane and trans-nonachlor) were attributed to PAH interference in the GC-ECD chromatogram...