C Brenner

Summary

Country: France

Publications

  1. ncbi Apoptosis. Mitochondria--the death signal integrators
    C Brenner
    Apoptosis, Cancer and Immunity Laboratory, National League Against Cancer, CNRS UMR1599, Institut Gustave Roussy, F 94805 Villejuif, France
    Science 289:1150-1. 2000
  2. ncbi The adenine nucleotide translocator: a target of nitric oxide, peroxynitrite, and 4-hydroxynonenal
    H L Vieira
    Centre National de la Recherche Scientifique, UMR1599, Institut Gustave Roussy, 39 rue Camille-Desmoulins, F-94805 Villejuif, France
    Oncogene 20:4305-16. 2001
  3. pmc Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2
    E Jacotot
    Centre National de la Recherche Scientifique, UMR 1599, Institut Gustave Roussy, F 94805 Villejuif, France
    J Exp Med 193:509-19. 2001
  4. ncbi Mitochondrial permeability transition as a novel principle of hepatorenal toxicity in vivo
    D Haouzi
    Centre National de la Recherche Scientifique, UMR1599, Institut Gustave Roussy, 39 rue Camille Desmoulins, F 94805 Villejuif, France
    Apoptosis 7:395-405. 2002
  5. ncbi Permeabilization of the mitochondrial inner membrane during apoptosis: impact of the adenine nucleotide translocator
    H L Vieira
    Centre National de la Recherche Scientifique, UMR1599, Institut Gustave Roussy, 39 rue Camille Desmoulins, F 94805 Villejuif, France
    Cell Death Differ 7:1146-54. 2000

Collaborators

  • J C Reed
  • G Feldmann
  • B P Roques
  • G Melino
  • G Kroemer
  • H L Vieira
  • D Haouzi
  • A S Belzacq
  • E Jacotot
  • C El Hamel
  • I Cohen
  • K F Ferri
  • M Castedo
  • N Vadrot
  • D Fau
  • D Poncet
  • P Boya
  • H L A Vieira
  • L M Bartle
  • M Geuskens
  • D Metivier
  • S Druillennec
  • M Loeffler
  • C Lenoir
  • J P Briand
  • F Bernassola
  • J Hoebeke
  • V Goldmacher
  • Z H Xie
  • P Rustin
  • N Zamzami
  • L Edelman

Detail Information

Publications5

  1. ncbi Apoptosis. Mitochondria--the death signal integrators
    C Brenner
    Apoptosis, Cancer and Immunity Laboratory, National League Against Cancer, CNRS UMR1599, Institut Gustave Roussy, F 94805 Villejuif, France
    Science 289:1150-1. 2000
    ....
  2. ncbi The adenine nucleotide translocator: a target of nitric oxide, peroxynitrite, and 4-hydroxynonenal
    H L Vieira
    Centre National de la Recherche Scientifique, UMR1599, Institut Gustave Roussy, 39 rue Camille-Desmoulins, F-94805 Villejuif, France
    Oncogene 20:4305-16. 2001
    ..Taken together these data suggest that NO, peroxynitrite, and HNE may directly act on ANT to induce mitochondrial membrane permeabilization and apoptosis...
  3. pmc Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2
    E Jacotot
    Centre National de la Recherche Scientifique, UMR 1599, Institut Gustave Roussy, F 94805 Villejuif, France
    J Exp Med 193:509-19. 2001
    ..Concomitantly, Bcl-2 suppresses channel formation by the ANT-Vpr complex in synthetic membranes. In conclusion, both Vpr and Bcl-2 modulate MMP through a direct interaction with ANT...
  4. ncbi Mitochondrial permeability transition as a novel principle of hepatorenal toxicity in vivo
    D Haouzi
    Centre National de la Recherche Scientifique, UMR1599, Institut Gustave Roussy, 39 rue Camille Desmoulins, F 94805 Villejuif, France
    Apoptosis 7:395-405. 2002
    ..Acetaminophen (paracetamol)-induced acute poisoning was also attenuated by CsA and GSH, both in vitro and in vivo. Altogether these data indicate that PTPC-mediated MMP may determine the hepatorenal toxicity of xenobiotics in vivo...
  5. ncbi Permeabilization of the mitochondrial inner membrane during apoptosis: impact of the adenine nucleotide translocator
    H L Vieira
    Centre National de la Recherche Scientifique, UMR1599, Institut Gustave Roussy, 39 rue Camille Desmoulins, F 94805 Villejuif, France
    Cell Death Differ 7:1146-54. 2000
    ..Although alternative mechanisms of mitochondrial membrane permeabilization may exist, ANT emerges as a major player in the regulation of cell death. Cell Death and Differentiation (2000) 7, 1146 - 1154..